Caenorhabditis elegans

70 known processes

tomm-40 (CELE_C18E9.6)

Protein TOMM-40

tomm-40 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.729
embryo development GO:0009790 3052 0.724
vesicle mediated transport GO:0016192 852 0.606
establishment of localization GO:0051234 1171 0.573
endocytosis GO:0006897 819 0.558
receptor mediated endocytosis GO:0006898 715 0.507
post embryonic development GO:0009791 2152 0.449
transport GO:0006810 1093 0.385
development of primary sexual characteristics GO:0045137 840 0.321
single organism reproductive process GO:0044702 1196 0.307
sexual reproduction GO:0019953 546 0.303
reproductive structure development GO:0048608 850 0.298
single organism localization GO:1902578 518 0.283
reproductive system development GO:0061458 850 0.269
macromolecular complex subunit organization GO:0043933 320 0.268
organelle organization GO:0006996 783 0.251
Human
gamete generation GO:0007276 461 0.250
single organism transport GO:0044765 447 0.244
developmental process involved in reproduction GO:0003006 1165 0.208
organic substance biosynthetic process GO:1901576 323 0.208
gonad development GO:0008406 840 0.203
determination of adult lifespan GO:0008340 812 0.200
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.198
multicellular organism reproduction GO:0032504 819 0.188
female gamete generation GO:0007292 254 0.185
aging GO:0007568 812 0.171
death GO:0016265 547 0.162
cellular component biogenesis GO:0044085 297 0.149
macromolecule biosynthetic process GO:0009059 250 0.146
multicellular organismal aging GO:0010259 812 0.144
multi organism reproductive process GO:0044703 867 0.134
germ cell development GO:0007281 351 0.132
hermaphrodite genitalia development GO:0040035 734 0.128
gene expression GO:0010467 412 0.127
oogenesis GO:0048477 229 0.125
organ development GO:0048513 1102 0.123
cellular protein metabolic process GO:0044267 279 0.121
cellular component assembly GO:0022607 293 0.121
protein complex subunit organization GO:0071822 280 0.121
multicellular organismal reproductive process GO:0048609 815 0.119
organic cyclic compound biosynthetic process GO:1901362 195 0.113
cellular biosynthetic process GO:0044249 315 0.108
regulation of macromolecule metabolic process GO:0060255 421 0.105
positive regulation of growth GO:0045927 369 0.101
sex differentiation GO:0007548 909 0.098
apoptotic process GO:0006915 478 0.095
positive regulation of multicellular organism growth GO:0040018 352 0.083
negative regulation of gene expression GO:0010629 217 0.083
negative regulation of biological process GO:0048519 567 0.079
cell development GO:0048468 696 0.079
macromolecular complex assembly GO:0065003 193 0.075
positive regulation of developmental growth GO:0048639 354 0.075
protein metabolic process GO:0019538 422 0.074
mitochondrion organization GO:0007005 20 0.074
Human
protein complex assembly GO:0006461 186 0.072
regulation of developmental process GO:0050793 684 0.071
small molecule metabolic process GO:0044281 186 0.070
positive regulation of developmental process GO:0051094 408 0.070
cell death GO:0008219 547 0.069
single organism organelle organization GO:1902589 501 0.063
aromatic compound biosynthetic process GO:0019438 192 0.061
cellular localization GO:0051641 360 0.060
nucleoside monophosphate metabolic process GO:0009123 46 0.060
programmed cell death GO:0012501 500 0.059
multicellular organism growth GO:0035264 385 0.059
regulation of metabolic process GO:0019222 478 0.057
genitalia development GO:0048806 741 0.054
developmental growth GO:0048589 412 0.054
growth GO:0040007 562 0.053
pronuclear migration GO:0035046 51 0.053
regulation of multicellular organismal process GO:0051239 726 0.053
organelle fission GO:0048285 363 0.053
protein targeting to mitochondrion GO:0006626 2 0.053
Human
macromolecule localization GO:0033036 771 0.052
signal transduction GO:0007165 317 0.052
lipid localization GO:0010876 573 0.051
heterocycle biosynthetic process GO:0018130 187 0.051
intracellular receptor signaling pathway GO:0030522 2 0.050
cellular macromolecular complex assembly GO:0034622 184 0.050
lipid storage GO:0019915 565 0.050
cellular protein complex assembly GO:0043623 178 0.050
regulation of gene expression GO:0010468 366 0.049
maintenance of location GO:0051235 580 0.049
nucleoside metabolic process GO:0009116 99 0.048
phagocytosis GO:0006909 115 0.046
response to wounding GO:0009611 4 0.045
nucleobase containing compound metabolic process GO:0006139 406 0.045
protein complex biogenesis GO:0070271 186 0.045
positive regulation of metabolic process GO:0009893 187 0.044
cellular macromolecule biosynthetic process GO:0034645 247 0.044
catabolic process GO:0009056 318 0.042
regulation of multicellular organism growth GO:0040014 373 0.042
biosynthetic process GO:0009058 323 0.041
regulation of growth GO:0040008 409 0.041
positive regulation of multicellular organismal process GO:0051240 417 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.040
regulation of biological quality GO:0065008 741 0.039
cellular nitrogen compound biosynthetic process GO:0044271 192 0.038
negative regulation of macromolecule metabolic process GO:0010605 229 0.038
body morphogenesis GO:0010171 620 0.037
transmembrane transport GO:0055085 110 0.035
carbohydrate derivative metabolic process GO:1901135 141 0.034
translation GO:0006412 37 0.034
negative regulation of metabolic process GO:0009892 240 0.034
regulation of primary metabolic process GO:0080090 292 0.033
cellular component assembly involved in morphogenesis GO:0010927 183 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.032
transcription dna templated GO:0006351 168 0.031
establishment of organelle localization GO:0051656 123 0.031
translational initiation GO:0006413 2 0.031
nucleic acid metabolic process GO:0090304 299 0.031
regulation of rna biosynthetic process GO:2001141 165 0.029
behavior GO:0007610 527 0.029
generation of precursor metabolites and energy GO:0006091 18 0.029
organonitrogen compound metabolic process GO:1901564 151 0.028
purine ribonucleotide metabolic process GO:0009150 95 0.028
molting cycle GO:0042303 281 0.027
cellular response to stress GO:0033554 162 0.027
apoptotic cell clearance GO:0043277 111 0.027
organelle assembly GO:0070925 214 0.027
regulation of transcription dna templated GO:0006355 164 0.027
nucleotide metabolic process GO:0009117 108 0.027
system process GO:0003008 136 0.026
regulation of developmental growth GO:0048638 389 0.025
ribose phosphate metabolic process GO:0019693 99 0.025
gene silencing GO:0016458 143 0.025
single organism catabolic process GO:0044712 129 0.025
oxoacid metabolic process GO:0043436 47 0.024
single fertilization GO:0007338 61 0.023
ribonucleoside triphosphate metabolic process GO:0009199 87 0.023
meiotic chromosome segregation GO:0045132 139 0.023
nucleobase containing small molecule metabolic process GO:0055086 115 0.023
mitochondrial respiratory chain complex assembly GO:0033108 1 0.022
regulation of response to wounding GO:1903034 1 0.022
phagocytosis engulfment GO:0006911 98 0.022
establishment of localization in cell GO:0051649 318 0.022
cellular protein modification process GO:0006464 207 0.022
nucleoside phosphate metabolic process GO:0006753 108 0.022
negative regulation of cellular process GO:0048523 239 0.022
phosphate containing compound metabolic process GO:0006796 232 0.022
transcription from rna polymerase ii promoter GO:0006366 149 0.022
organic substance catabolic process GO:1901575 294 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.022
single organism biosynthetic process GO:0044711 91 0.021
cytoskeleton organization GO:0007010 339 0.021
nucleobase containing compound biosynthetic process GO:0034654 184 0.021
locomotion GO:0040011 1634 0.021
ribonucleoside catabolic process GO:0042454 77 0.020
chromosome organization GO:0051276 104 0.020
secretion GO:0046903 147 0.020
secretion by cell GO:0032940 138 0.020
regulation of atp catabolic process GO:1903289 3 0.020
protein modification process GO:0036211 207 0.020
nucleic acid templated transcription GO:0097659 169 0.020
regulation of gene expression epigenetic GO:0040029 163 0.019
dna metabolic process GO:0006259 74 0.019
organic acid metabolic process GO:0006082 47 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.019
oxidation reduction process GO:0055114 59 0.019
purine containing compound metabolic process GO:0072521 95 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.019
phosphorus metabolic process GO:0006793 232 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
organophosphate metabolic process GO:0019637 125 0.019
purine nucleoside metabolic process GO:0042278 92 0.018
negative regulation of nucleic acid templated transcription GO:1903507 53 0.018
membrane invagination GO:0010324 98 0.018
actin cytoskeleton organization GO:0030036 184 0.018
cellular respiration GO:0045333 9 0.018
gene silencing by rna GO:0031047 143 0.018
protein refolding GO:0042026 1 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.018
oxidative phosphorylation GO:0006119 11 0.018
response to abiotic stimulus GO:0009628 152 0.018
macromolecule catabolic process GO:0009057 202 0.018
ribonucleoside metabolic process GO:0009119 98 0.017
macromolecule modification GO:0043412 218 0.017
ribonucleoside monophosphate metabolic process GO:0009161 45 0.017
regulation of cellular biosynthetic process GO:0031326 189 0.017
posttranscriptional gene silencing GO:0016441 143 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.017
regulation of cellular metabolic process GO:0031323 305 0.017
chromatin modification GO:0016568 32 0.017
regulation of behavior GO:0050795 97 0.016
regulation of macromolecule biosynthetic process GO:0010556 189 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
meiotic cell cycle process GO:1903046 170 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
purine nucleoside triphosphate metabolic process GO:0009144 87 0.016
proteolysis GO:0006508 61 0.016
ion transmembrane transport GO:0034220 91 0.016
single organism signaling GO:0044700 401 0.015
myosin filament organization GO:0031033 138 0.015
rna biosynthetic process GO:0032774 169 0.015
regulation of nucleic acid templated transcription GO:1903506 165 0.015
feeding behavior GO:0007631 70 0.015
microtubule based process GO:0007017 182 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
rna interference GO:0016246 137 0.015
inorganic ion transmembrane transport GO:0098660 54 0.014
striated muscle cell differentiation GO:0051146 158 0.014
regulation of rna metabolic process GO:0051252 173 0.014
cellular nitrogen compound catabolic process GO:0044270 119 0.014
inorganic cation transmembrane transport GO:0098662 46 0.014
organonitrogen compound catabolic process GO:1901565 90 0.014
purine ribonucleoside metabolic process GO:0046128 92 0.014
localization of cell GO:0051674 313 0.014
actomyosin structure organization GO:0031032 154 0.014
muscle cell differentiation GO:0042692 171 0.014
atp metabolic process GO:0046034 42 0.014
positive regulation of cellular process GO:0048522 332 0.014
muscle tissue development GO:0060537 1 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
negative regulation of transcription dna templated GO:0045892 53 0.014
fertilization GO:0009566 63 0.014
multi multicellular organism process GO:0044706 390 0.013
regeneration GO:0031099 4 0.013
cation transmembrane transport GO:0098655 59 0.013
myosin filament assembly GO:0031034 138 0.013
signaling GO:0023052 401 0.013
negative regulation of rna biosynthetic process GO:1902679 53 0.013
purine nucleotide metabolic process GO:0006163 95 0.013
muscle structure development GO:0061061 191 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.012
negative regulation of rna metabolic process GO:0051253 53 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
synaptic transmission GO:0007268 106 0.012
response to external stimulus GO:0009605 289 0.012
negative regulation of biosynthetic process GO:0009890 65 0.012
ion transport GO:0006811 113 0.011
cation transport GO:0006812 78 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
cellular component morphogenesis GO:0032989 318 0.011
digestive tract development GO:0048565 122 0.011
engulfment of apoptotic cell GO:0043652 94 0.011
protein localization to mitochondrion GO:0070585 2 0.011
Human
multicellular organismal reproductive behavior GO:0033057 384 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.011
anatomical structure formation involved in morphogenesis GO:0048646 250 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
regulation of response to stimulus GO:0048583 243 0.011
rna metabolic process GO:0016070 228 0.011
cellular component movement GO:0006928 388 0.011
myofibril assembly GO:0030239 154 0.011
chromosome segregation GO:0007059 180 0.010
regulation of signaling GO:0023051 172 0.010
regulation of biosynthetic process GO:0009889 189 0.010
cellular catabolic process GO:0044248 199 0.010

tomm-40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.048
disease of anatomical entity DOID:7 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
inherited metabolic disorder DOID:655 0 0.012