Caenorhabditis elegans

32 known processes

ptc-3 (CELE_Y110A2AL.8)

Protein PTC-3

ptc-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.618
embryo development GO:0009790 3052 0.488
vesicle mediated transport GO:0016192 852 0.460
Worm Fly
sexual reproduction GO:0019953 546 0.430
Worm Fly
locomotion GO:0040011 1634 0.406
cell cycle process GO:0022402 482 0.364
transport GO:0006810 1093 0.333
Worm Fly
organelle organization GO:0006996 783 0.309
death GO:0016265 547 0.305
Fly
cellular localization GO:0051641 360 0.258
Fly
endocytosis GO:0006897 819 0.223
Worm Fly
cell death GO:0008219 547 0.212
Fly
establishment of localization GO:0051234 1171 0.189
Worm Fly
single organism reproductive process GO:0044702 1196 0.185
Worm Fly
apoptotic process GO:0006915 478 0.185
Fly
organelle fission GO:0048285 363 0.182
organic substance catabolic process GO:1901575 294 0.179
protein catabolic process GO:0030163 162 0.172
determination of adult lifespan GO:0008340 812 0.164
multicellular organismal aging GO:0010259 812 0.162
regulation of metabolic process GO:0019222 478 0.155
cell cycle GO:0007049 526 0.154
Mouse Fly
female gamete generation GO:0007292 254 0.148
Worm Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.146
sex differentiation GO:0007548 909 0.145
Fly
regulation of cell cycle GO:0051726 194 0.144
Mouse Fly
phosphate containing compound metabolic process GO:0006796 232 0.144
multi organism reproductive process GO:0044703 867 0.139
Worm Fly
programmed cell death GO:0012501 500 0.138
Fly
receptor mediated endocytosis GO:0006898 715 0.134
Worm Fly
nucleobase containing compound metabolic process GO:0006139 406 0.129
single organism transport GO:0044765 447 0.128
Fly
meiotic nuclear division GO:0007126 300 0.122
protein metabolic process GO:0019538 422 0.121
Mouse
aging GO:0007568 812 0.119
hermaphrodite genitalia development GO:0040035 734 0.119
establishment of localization in cell GO:0051649 318 0.117
Fly
cell surface receptor signaling pathway GO:0007166 149 0.115
Zebrafish Mouse Fly
single organism localization GO:1902578 518 0.111
Fly
establishment of cell polarity GO:0030010 46 0.109
signal transduction GO:0007165 317 0.100
Zebrafish Mouse Fly
catabolic process GO:0009056 318 0.100
nucleobase containing compound catabolic process GO:0034655 114 0.098
reproductive structure development GO:0048608 850 0.097
Fly
developmental process involved in reproduction GO:0003006 1165 0.096
Worm Fly
cellular response to stress GO:0033554 162 0.088
establishment or maintenance of cell polarity GO:0007163 63 0.088
positive regulation of developmental process GO:0051094 408 0.085
secretion GO:0046903 147 0.084
microtubule based process GO:0007017 182 0.083
cellular protein metabolic process GO:0044267 279 0.082
multicellular organismal reproductive process GO:0048609 815 0.081
Worm Fly
negative regulation of biological process GO:0048519 567 0.080
Zebrafish Mouse Fly
regulation of developmental process GO:0050793 684 0.080
multicellular organism growth GO:0035264 385 0.079
growth GO:0040007 562 0.079
establishment of organelle localization GO:0051656 123 0.075
localization of cell GO:0051674 313 0.074
Fly
gamete generation GO:0007276 461 0.074
Worm Fly
regulation of cytoplasmic transport GO:1903649 3 0.074
Fly
cytoskeleton organization GO:0007010 339 0.072
macromolecule catabolic process GO:0009057 202 0.070
meiotic cell cycle GO:0051321 335 0.069
developmental growth GO:0048589 412 0.068
establishment of mitotic spindle orientation GO:0000132 28 0.067
gonad development GO:0008406 840 0.066
Fly
cell development GO:0048468 696 0.066
Zebrafish Worm Fly
phosphorus metabolic process GO:0006793 232 0.065
multi organism reproductive behavior GO:0044705 387 0.065
Worm
regulation of post embryonic development GO:0048580 260 0.063
cell migration GO:0016477 306 0.062
Fly
maintenance of location GO:0051235 580 0.062
Worm
head development GO:0060322 1 0.062
Mouse
macromolecule localization GO:0033036 771 0.062
Mouse Worm Fly
cell motility GO:0048870 313 0.062
Fly
nucleotide metabolic process GO:0009117 108 0.061
regulation of biological quality GO:0065008 741 0.061
Mouse Worm Fly
positive regulation of multicellular organism growth GO:0040018 352 0.058
positive regulation of growth GO:0045927 369 0.057
lipid localization GO:0010876 573 0.057
Worm
single organism signaling GO:0044700 401 0.054
Zebrafish Mouse Fly
negative regulation of nematode larval development GO:0061064 208 0.054
lipid storage GO:0019915 565 0.053
Worm
taxis GO:0042330 128 0.052
Zebrafish Fly
purine nucleoside triphosphate metabolic process GO:0009144 87 0.052
regulation of nitrogen compound metabolic process GO:0051171 222 0.052
macromolecule modification GO:0043412 218 0.051
oogenesis GO:0048477 229 0.050
Worm Fly
regulation of macromolecule metabolic process GO:0060255 421 0.050
response to chemical GO:0042221 356 0.050
Zebrafish Mouse Fly
regulation of nematode larval development GO:0061062 260 0.049
cellular component movement GO:0006928 388 0.049
Zebrafish Fly
phagocytosis GO:0006909 115 0.048
cell division GO:0051301 262 0.048
Mouse
genitalia development GO:0048806 741 0.047
response to external stimulus GO:0009605 289 0.046
Zebrafish Fly
positive regulation of multicellular organismal process GO:0051240 417 0.044
cellular component assembly involved in morphogenesis GO:0010927 183 0.043
organ development GO:0048513 1102 0.043
Zebrafish Mouse Fly
germ cell development GO:0007281 351 0.042
Worm Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.042
Worm Fly
cellular component morphogenesis GO:0032989 318 0.041
Zebrafish Fly
nucleic acid metabolic process GO:0090304 299 0.041
mitotic cell cycle process GO:1903047 194 0.040
regulation of macromolecule biosynthetic process GO:0010556 189 0.040
positive regulation of cellular process GO:0048522 332 0.040
regulation of nucleocytoplasmic transport GO:0046822 3 0.039
Fly
macromolecular complex subunit organization GO:0043933 320 0.039
negative regulation of multicellular organismal process GO:0051241 236 0.039
Zebrafish Mouse
cellular component biogenesis GO:0044085 297 0.038
body morphogenesis GO:0010171 620 0.037
negative regulation of vulval development GO:0040027 206 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.037
establishment of spindle localization GO:0051293 51 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
establishment of spindle orientation GO:0051294 34 0.035
regulation of vulval development GO:0040028 248 0.035
cellular response to chemical stimulus GO:0070887 129 0.035
Mouse
regulation of growth GO:0040008 409 0.034
defense response GO:0006952 296 0.034
adult behavior GO:0030534 3 0.034
organelle localization GO:0051640 127 0.033
single organism organelle organization GO:1902589 501 0.033
regulation of signal transduction GO:0009966 135 0.033
Zebrafish Mouse Fly
regulation of developmental growth GO:0048638 389 0.033
negative regulation of cellular process GO:0048523 239 0.032
Zebrafish Mouse Fly
purine ribonucleotide catabolic process GO:0009154 75 0.031
macromolecule biosynthetic process GO:0009059 250 0.031
striated muscle cell development GO:0055002 157 0.031
regulation of cellular component organization GO:0051128 248 0.031
cellular protein modification process GO:0006464 207 0.031
biosynthetic process GO:0009058 323 0.031
multi organism behavior GO:0051705 389 0.030
Worm
multicellular organism reproduction GO:0032504 819 0.030
Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.030
development of primary sexual characteristics GO:0045137 840 0.029
Fly
small molecule metabolic process GO:0044281 186 0.029
establishment of mitotic spindle localization GO:0040001 41 0.029
purine nucleotide metabolic process GO:0006163 95 0.029
negative regulation of metabolic process GO:0009892 240 0.028
spindle localization GO:0051653 51 0.028
single organism cellular localization GO:1902580 72 0.028
Fly
regulation of cellular metabolic process GO:0031323 305 0.028
secretion by cell GO:0032940 138 0.028
negative regulation of macromolecule metabolic process GO:0010605 229 0.027
regulation of multicellular organismal process GO:0051239 726 0.027
negative regulation of developmental process GO:0051093 227 0.027
Zebrafish Mouse
regulation of multicellular organismal development GO:2000026 317 0.027
Zebrafish Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.026
organelle assembly GO:0070925 214 0.026
regulation of gene expression GO:0010468 366 0.026
muscle cell development GO:0055001 158 0.026
rna metabolic process GO:0016070 228 0.026
protein modification process GO:0036211 207 0.026
regulation of signaling GO:0023051 172 0.026
Zebrafish Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.026
Mouse
single organism intracellular transport GO:1902582 70 0.026
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.025
inductive cell migration GO:0040039 145 0.024
phagocytosis engulfment GO:0006911 98 0.024
regulation of protein localization GO:0032880 50 0.024
Mouse Fly
fertilization GO:0009566 63 0.024
negative regulation of cellular metabolic process GO:0031324 95 0.024
mitotic nuclear division GO:0007067 89 0.023
regulation of cell communication GO:0010646 176 0.023
Zebrafish Mouse Fly
gene silencing GO:0016458 143 0.023
positive regulation of developmental growth GO:0048639 354 0.023
reproductive system development GO:0061458 850 0.022
Fly
protein complex subunit organization GO:0071822 280 0.022
regulation of cell cycle process GO:0010564 145 0.022
nucleoside metabolic process GO:0009116 99 0.022
striated muscle cell differentiation GO:0051146 158 0.021
nucleoside phosphate metabolic process GO:0006753 108 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.020
defense response to gram negative bacterium GO:0050829 64 0.020
positive regulation of protein transport GO:0051222 4 0.020
post embryonic organ development GO:0048569 336 0.020
Fly
embryonic morphogenesis GO:0048598 152 0.020
Mouse
nucleic acid templated transcription GO:0097659 169 0.020
membrane invagination GO:0010324 98 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
peptidyl amino acid modification GO:0018193 58 0.019
reproductive behavior GO:0019098 387 0.019
Worm
ribonucleotide metabolic process GO:0009259 99 0.019
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
response to external biotic stimulus GO:0043207 101 0.019
ribonucleoside triphosphate metabolic process GO:0009199 87 0.019
aromatic compound catabolic process GO:0019439 116 0.019
adult locomotory behavior GO:0008344 1 0.018
heterocycle catabolic process GO:0046700 119 0.018
embryonic body morphogenesis GO:0010172 49 0.018
nucleoside triphosphate metabolic process GO:0009141 87 0.018
cellular nitrogen compound catabolic process GO:0044270 119 0.018
positive regulation of intracellular transport GO:0032388 2 0.018
regulation of organelle organization GO:0033043 164 0.018
purine ribonucleotide metabolic process GO:0009150 95 0.018
single organism catabolic process GO:0044712 129 0.018
negative regulation of gene expression GO:0010629 217 0.018
neuron projection guidance GO:0097485 82 0.017
Zebrafish Fly
actin cytoskeleton organization GO:0030036 184 0.017
nucleobase containing small molecule metabolic process GO:0055086 115 0.017
organophosphate metabolic process GO:0019637 125 0.017
actomyosin structure organization GO:0031032 154 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
response to other organism GO:0051707 101 0.017
molting cycle GO:0042303 281 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
nucleotide catabolic process GO:0009166 77 0.017
cellular catabolic process GO:0044248 199 0.017
nuclear migration GO:0007097 54 0.017
macromolecular complex assembly GO:0065003 193 0.017
posttranscriptional regulation of gene expression GO:0010608 166 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.016
myosin filament organization GO:0031033 138 0.016
positive regulation of metabolic process GO:0009893 187 0.016
myofibril assembly GO:0030239 154 0.016
multi multicellular organism process GO:0044706 390 0.016
Worm
dauer larval development GO:0040024 92 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.016
response to abiotic stimulus GO:0009628 152 0.016
protein localization GO:0008104 205 0.016
Mouse Fly
regulation of gene expression epigenetic GO:0040029 163 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.015
apoptotic cell clearance GO:0043277 111 0.015
defense response to other organism GO:0098542 100 0.015
protein transport GO:0015031 45 0.015
Fly
nervous system development GO:0007399 253 0.015
Zebrafish Mouse Fly
vulval development GO:0040025 333 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
cell cell signaling GO:0007267 118 0.015
cytokinesis GO:0000910 80 0.015
glycosyl compound catabolic process GO:1901658 79 0.015
regulation of locomotion GO:0040012 161 0.015
Fly
nucleoside catabolic process GO:0009164 78 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
chemotaxis GO:0006935 120 0.014
Zebrafish Fly
organophosphate catabolic process GO:0046434 81 0.014
regulation of phosphorus metabolic process GO:0051174 81 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
tissue development GO:0009888 112 0.014
Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 184 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.014
cell maturation GO:0048469 26 0.014
golgi vesicle transport GO:0048193 3 0.014
regulation of cell division GO:0051302 142 0.013
Mouse
cellular component assembly GO:0022607 293 0.013
positive regulation of cell projection organization GO:0031346 4 0.013
actin filament based process GO:0030029 191 0.013
positive regulation of catalytic activity GO:0043085 59 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
epithelial cell proliferation GO:0050673 1 0.013
Mouse
myosin filament assembly GO:0031034 138 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
regulation of biosynthetic process GO:0009889 189 0.012
organic substance biosynthetic process GO:1901576 323 0.012
transcription dna templated GO:0006351 168 0.012
intracellular signal transduction GO:0035556 96 0.012
neurogenesis GO:0022008 236 0.012
Zebrafish Mouse Fly
regulation of phosphate metabolic process GO:0019220 81 0.012
glycosyl compound metabolic process GO:1901657 100 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
ribonucleoside monophosphate metabolic process GO:0009161 45 0.012
ribonucleoside catabolic process GO:0042454 77 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
response to bacterium GO:0009617 86 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
chromosome organization GO:0051276 104 0.012
protein complex assembly GO:0006461 186 0.012
establishment of nucleus localization GO:0040023 55 0.012
regulation of intracellular signal transduction GO:1902531 77 0.011
single fertilization GO:0007338 61 0.011
cellular biosynthetic process GO:0044249 315 0.011
protein phosphorylation GO:0006468 85 0.011
axon development GO:0061564 163 0.011
Zebrafish Fly
positive regulation of cellular metabolic process GO:0031325 178 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
cell projection organization GO:0030030 231 0.011
Zebrafish Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.011
regulation of primary metabolic process GO:0080090 292 0.011
positive regulation of intracellular protein transport GO:0090316 2 0.011
purine nucleoside triphosphate catabolic process GO:0009146 72 0.010
digestive tract morphogenesis GO:0048546 76 0.010
pronuclear migration GO:0035046 51 0.010
organic substance transport GO:0071702 113 0.010
Fly
posttranscriptional gene silencing GO:0016441 143 0.010
cellular macromolecular complex assembly GO:0034622 184 0.010
membrane organization GO:0061024 135 0.010

ptc-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.065
muscular disease DOID:0080000 0 0.065
heart disease DOID:114 0 0.065
cardiomyopathy DOID:0050700 0 0.065
disease of anatomical entity DOID:7 0 0.065
cardiovascular system disease DOID:1287 0 0.065
musculoskeletal system disease DOID:17 0 0.065
muscle tissue disease DOID:66 0 0.065