Caenorhabditis elegans

7 known processes

mel-46 (CELE_T06A10.1)

Protein MEL-46

mel-46 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.294
single organism reproductive process GO:0044702 1196 0.218
Mouse
embryo development GO:0009790 3052 0.216
establishment of localization GO:0051234 1171 0.168
growth GO:0040007 562 0.145
regulation of developmental process GO:0050793 684 0.143
multicellular organism reproduction GO:0032504 819 0.134
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.122
Human Mouse
post embryonic development GO:0009791 2152 0.120
organelle organization GO:0006996 783 0.119
regulation of metabolic process GO:0019222 478 0.119
Mouse
multicellular organismal reproductive process GO:0048609 815 0.115
Mouse
development of primary sexual characteristics GO:0045137 840 0.110
gamete generation GO:0007276 461 0.106
Mouse
locomotion GO:0040011 1634 0.106
organ development GO:0048513 1102 0.103
regulation of multicellular organismal process GO:0051239 726 0.101
vesicle mediated transport GO:0016192 852 0.100
determination of adult lifespan GO:0008340 812 0.093
aging GO:0007568 812 0.093
positive regulation of multicellular organismal process GO:0051240 417 0.093
transport GO:0006810 1093 0.093
multi organism reproductive process GO:0044703 867 0.088
Mouse
negative regulation of biological process GO:0048519 567 0.087
Mouse
receptor mediated endocytosis GO:0006898 715 0.085
developmental process involved in reproduction GO:0003006 1165 0.081
Mouse
developmental growth GO:0048589 412 0.081
sex differentiation GO:0007548 909 0.080
multicellular organismal aging GO:0010259 812 0.079
organic substance catabolic process GO:1901575 294 0.078
nucleic acid metabolic process GO:0090304 299 0.077
Human Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.075
Mouse
neuron projection development GO:0031175 187 0.074
endocytosis GO:0006897 819 0.074
negative regulation of metabolic process GO:0009892 240 0.073
Mouse
generation of neurons GO:0048699 235 0.073
cell death GO:0008219 547 0.072
Human Mouse
catabolic process GO:0009056 318 0.072
axon development GO:0061564 163 0.071
regulation of gene expression GO:0010468 366 0.070
Mouse
organelle fission GO:0048285 363 0.069
neuron differentiation GO:0030182 217 0.067
cell projection organization GO:0030030 231 0.066
regulation of primary metabolic process GO:0080090 292 0.066
Mouse
nervous system development GO:0007399 253 0.064
multicellular organism growth GO:0035264 385 0.064
programmed cell death GO:0012501 500 0.063
Human Mouse
meiotic cell cycle GO:0051321 335 0.063
neurogenesis GO:0022008 236 0.063
regulation of growth GO:0040008 409 0.061
negative regulation of cellular process GO:0048523 239 0.061
Mouse
regulation of biological quality GO:0065008 741 0.061
macromolecule localization GO:0033036 771 0.060
single organism localization GO:1902578 518 0.059
gene expression GO:0010467 412 0.057
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.057
negative regulation of macromolecule metabolic process GO:0010605 229 0.056
Mouse
lipid localization GO:0010876 573 0.056
sexual reproduction GO:0019953 546 0.056
Mouse
cellular biosynthetic process GO:0044249 315 0.055
Mouse
positive regulation of growth GO:0045927 369 0.054
lipid storage GO:0019915 565 0.054
regulation of multicellular organism growth GO:0040014 373 0.054
regulation of developmental growth GO:0048638 389 0.054
behavior GO:0007610 527 0.054
Fly
regulation of vulval development GO:0040028 248 0.053
maintenance of location GO:0051235 580 0.052
positive regulation of developmental process GO:0051094 408 0.050
positive regulation of developmental growth GO:0048639 354 0.050
regulation of nitrogen compound metabolic process GO:0051171 222 0.050
Mouse
regulation of response to stimulus GO:0048583 243 0.049
protein metabolic process GO:0019538 422 0.048
organic substance biosynthetic process GO:1901576 323 0.048
Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.047
neuron development GO:0048666 199 0.047
death GO:0016265 547 0.047
Human Mouse
organic cyclic compound catabolic process GO:1901361 119 0.045
reproductive structure development GO:0048608 850 0.045
cell cycle GO:0007049 526 0.044
cell development GO:0048468 696 0.044
Mouse
multi organism reproductive behavior GO:0044705 387 0.043
meiotic nuclear division GO:0007126 300 0.043
cellular component biogenesis GO:0044085 297 0.041
Human Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.041
Mouse
post embryonic organ development GO:0048569 336 0.041
aromatic compound biosynthetic process GO:0019438 192 0.041
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.040
reproductive behavior GO:0019098 387 0.040
reproductive system development GO:0061458 850 0.040
response to external stimulus GO:0009605 289 0.040
multi multicellular organism process GO:0044706 390 0.040
cell division GO:0051301 262 0.040
cellular nitrogen compound catabolic process GO:0044270 119 0.039
signal transduction GO:0007165 317 0.039
rrna metabolic process GO:0016072 3 0.039
heterocycle catabolic process GO:0046700 119 0.039
regulation of cell communication GO:0010646 176 0.038
signaling GO:0023052 401 0.037
nucleobase containing compound catabolic process GO:0034655 114 0.037
ribose phosphate metabolic process GO:0019693 99 0.036
response to wounding GO:0009611 4 0.036
ribonucleotide metabolic process GO:0009259 99 0.035
chromosome segregation GO:0007059 180 0.035
posttranscriptional gene silencing GO:0016441 143 0.035
cellular protein metabolic process GO:0044267 279 0.035
apoptotic process GO:0006915 478 0.034
Human Mouse
negative regulation of gene expression GO:0010629 217 0.034
Mouse
regulation of nematode larval development GO:0061062 260 0.034
cellular component assembly GO:0022607 293 0.034
Human Fly
single organism signaling GO:0044700 401 0.033
germ cell development GO:0007281 351 0.033
Mouse
phosphorus metabolic process GO:0006793 232 0.033
carbohydrate derivative metabolic process GO:1901135 141 0.033
intracellular signal transduction GO:0035556 96 0.033
hermaphrodite genitalia development GO:0040035 734 0.032
gene silencing by rna GO:0031047 143 0.032
multi organism behavior GO:0051705 389 0.032
rna interference GO:0016246 137 0.032
oviposition GO:0018991 364 0.032
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.032
posttranscriptional gene silencing by rna GO:0035194 143 0.032
gene silencing GO:0016458 143 0.032
regulation of rna metabolic process GO:0051252 173 0.032
Mouse
nucleoside catabolic process GO:0009164 78 0.032
regulation of signaling GO:0023051 172 0.031
female gamete generation GO:0007292 254 0.030
Mouse
purine ribonucleotide metabolic process GO:0009150 95 0.030
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.030
Mouse
regulation of signal transduction GO:0009966 135 0.030
cellular component movement GO:0006928 388 0.030
glycosyl compound metabolic process GO:1901657 100 0.030
regulation of cellular metabolic process GO:0031323 305 0.030
Mouse
regulation of cellular component organization GO:0051128 248 0.030
positive regulation of cellular process GO:0048522 332 0.029
Human Mouse
oogenesis GO:0048477 229 0.029
Mouse
nucleoside phosphate metabolic process GO:0006753 108 0.029
rna metabolic process GO:0016070 228 0.028
Human Mouse
gonad development GO:0008406 840 0.028
regulation of gene expression epigenetic GO:0040029 163 0.028
phosphate containing compound metabolic process GO:0006796 232 0.028
body morphogenesis GO:0010171 620 0.028
regulation of intracellular signal transduction GO:1902531 77 0.028
small molecule metabolic process GO:0044281 186 0.028
multicellular organismal reproductive behavior GO:0033057 384 0.027
meiotic chromosome segregation GO:0045132 139 0.027
vulval development GO:0040025 333 0.027
regulation of biosynthetic process GO:0009889 189 0.027
Mouse
regulation of response to wounding GO:1903034 1 0.027
single organism transport GO:0044765 447 0.026
nucleobase containing small molecule metabolic process GO:0055086 115 0.025
purine containing compound metabolic process GO:0072521 95 0.025
molting cycle GO:0042303 281 0.025
biosynthetic process GO:0009058 323 0.025
Mouse
defense response GO:0006952 296 0.025
response to chemical GO:0042221 356 0.025
regulation of multicellular organismal development GO:2000026 317 0.025
positive regulation of neurogenesis GO:0050769 4 0.024
cellular catabolic process GO:0044248 199 0.024
small gtpase mediated signal transduction GO:0007264 32 0.024
cellular response to stress GO:0033554 162 0.023
regulation of post embryonic development GO:0048580 260 0.023
macromolecule catabolic process GO:0009057 202 0.023
organophosphate metabolic process GO:0019637 125 0.023
negative regulation of cellular metabolic process GO:0031324 95 0.023
Mouse
negative regulation of developmental process GO:0051093 227 0.023
neuron recognition GO:0008038 83 0.023
regulation of neuron projection development GO:0010975 31 0.023
cell proliferation GO:0008283 116 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.022
negative regulation of cellular biosynthetic process GO:0031327 65 0.022
Mouse
macromolecule biosynthetic process GO:0009059 250 0.022
Mouse
aromatic compound catabolic process GO:0019439 116 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.022
protein modification process GO:0036211 207 0.022
dna metabolic process GO:0006259 74 0.022
nucleoside metabolic process GO:0009116 99 0.021
cell migration GO:0016477 306 0.021
ribonucleoside metabolic process GO:0009119 98 0.021
inductive cell migration GO:0040039 145 0.021
negative regulation of nematode larval development GO:0061064 208 0.020
cellular component morphogenesis GO:0032989 318 0.020
genitalia development GO:0048806 741 0.020
ribonucleotide catabolic process GO:0009261 75 0.020
phagocytosis GO:0006909 115 0.020
nucleotide metabolic process GO:0009117 108 0.020
carbohydrate derivative catabolic process GO:1901136 82 0.020
purine containing compound catabolic process GO:0072523 75 0.020
rna localization GO:0006403 3 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
purine nucleoside catabolic process GO:0006152 75 0.019
purine nucleoside triphosphate catabolic process GO:0009146 72 0.019
developmental cell growth GO:0048588 39 0.019
response to other organism GO:0051707 101 0.019
positive regulation of response to stimulus GO:0048584 55 0.019
purine nucleoside triphosphate metabolic process GO:0009144 87 0.019
cellular protein modification process GO:0006464 207 0.019
cell part morphogenesis GO:0032990 152 0.019
regulation of apoptotic signaling pathway GO:2001233 1 0.018
macromolecular complex assembly GO:0065003 193 0.018
Human Fly
nucleoside triphosphate metabolic process GO:0009141 87 0.018
regulation of meiosis GO:0040020 94 0.018
glycosyl compound catabolic process GO:1901658 79 0.018
regulation of cell cycle GO:0051726 194 0.018
cellular localization GO:0051641 360 0.018
positive regulation of neuron differentiation GO:0045666 4 0.018
ribonucleoside triphosphate catabolic process GO:0009203 72 0.018
cell motility GO:0048870 313 0.018
cell type specific apoptotic process GO:0097285 4 0.018
regulation of cell differentiation GO:0045595 81 0.018
cell projection morphogenesis GO:0048858 148 0.018
positive regulation of macromolecule metabolic process GO:0010604 149 0.017
cell cycle process GO:0022402 482 0.017
macromolecular complex subunit organization GO:0043933 320 0.017
Human Fly
head development GO:0060322 1 0.017
ribonucleoside monophosphate metabolic process GO:0009161 45 0.017
epithelial tube morphogenesis GO:0060562 1 0.017
rna biosynthetic process GO:0032774 169 0.017
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 87 0.017
regulation of transcription dna templated GO:0006355 164 0.017
Mouse
nucleic acid templated transcription GO:0097659 169 0.016
Mouse
single organism catabolic process GO:0044712 129 0.016
neuron projection morphogenesis GO:0048812 114 0.016
positive regulation of metabolic process GO:0009893 187 0.016
negative regulation of vulval development GO:0040027 206 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
purine nucleotide catabolic process GO:0006195 75 0.016
single organism organelle organization GO:1902589 501 0.016
positive regulation of signaling GO:0023056 66 0.016
establishment of localization in cell GO:0051649 318 0.016
regulation of meiotic cell cycle GO:0051445 136 0.016
localization of cell GO:0051674 313 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.016
Mouse
apoptotic cell clearance GO:0043277 111 0.016
regulation of localization GO:0032879 194 0.016
regulation of molecular function GO:0065009 89 0.016
skeletal muscle organ development GO:0060538 3 0.016
regulation of neurogenesis GO:0050767 40 0.015
purine nucleoside metabolic process GO:0042278 92 0.015
axonogenesis GO:0007409 102 0.015
regulation of organelle organization GO:0033043 164 0.015
negative regulation of post embryonic development GO:0048581 208 0.015
rho protein signal transduction GO:0007266 2 0.015
regulation of neuron differentiation GO:0045664 40 0.015
protein complex assembly GO:0006461 186 0.015
muscle tissue development GO:0060537 1 0.015
regulation of macromolecule biosynthetic process GO:0010556 189 0.015
Mouse
nucleoside phosphate catabolic process GO:1901292 77 0.014
organophosphate catabolic process GO:0046434 81 0.014
negative regulation of multicellular organismal process GO:0051241 236 0.014
ribonucleoside catabolic process GO:0042454 77 0.014
regulation of anatomical structure size GO:0090066 46 0.014
purine ribonucleotide catabolic process GO:0009154 75 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
nucleoside triphosphate catabolic process GO:0009143 72 0.014
positive regulation of cell communication GO:0010647 69 0.014
response to abiotic stimulus GO:0009628 152 0.014
purine ribonucleoside metabolic process GO:0046128 92 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.014
rrna processing GO:0006364 3 0.014
neuromuscular junction development GO:0007528 2 0.014
Fly
purine ribonucleoside catabolic process GO:0046130 75 0.014
response to external biotic stimulus GO:0043207 101 0.014
phagocytosis engulfment GO:0006911 98 0.014
actin cytoskeleton organization GO:0030036 184 0.013
protein complex biogenesis GO:0070271 186 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
innate immune response GO:0045087 190 0.013
regulation of cell division GO:0051302 142 0.013
cellular protein complex assembly GO:0043623 178 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
Mouse
nucleotide catabolic process GO:0009166 77 0.013
cellular nitrogen compound biosynthetic process GO:0044271 192 0.013
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
regulation of cellular biosynthetic process GO:0031326 189 0.013
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.013
cell morphogenesis involved in differentiation GO:0000904 112 0.013
positive regulation of cellular metabolic process GO:0031325 178 0.013
regulation of cell development GO:0060284 49 0.012
intraspecies interaction between organisms GO:0051703 3 0.012
cytoskeleton organization GO:0007010 339 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
membrane invagination GO:0010324 98 0.012
macromolecule modification GO:0043412 218 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
cuticle development GO:0042335 100 0.012
regulation of rna biosynthetic process GO:2001141 165 0.012
Mouse
immune response GO:0006955 192 0.012
response to organic substance GO:0010033 131 0.012
cellular response to chemical stimulus GO:0070887 129 0.012
muscle cell differentiation GO:0042692 171 0.012
regulation of nucleic acid templated transcription GO:1903506 165 0.011
Mouse
adult locomotory behavior GO:0008344 1 0.011
Fly
chromosome organization GO:0051276 104 0.011
axonal fasciculation GO:0007413 79 0.011
response to biotic stimulus GO:0009607 101 0.011
nucleobase containing compound biosynthetic process GO:0034654 184 0.011
Mouse
muscle structure development GO:0061061 191 0.011
protein complex subunit organization GO:0071822 280 0.011
regulation of cell death GO:0010941 65 0.011
Human Mouse
chemotaxis GO:0006935 120 0.011
regulation of cell projection organization GO:0031344 38 0.011
embryonic morphogenesis GO:0048598 152 0.011
myosin filament organization GO:0031033 138 0.011
cell morphogenesis GO:0000902 163 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
Mouse
regulation of cell proliferation GO:0042127 105 0.011
cellular ketone metabolic process GO:0042180 14 0.011
cell recognition GO:0008037 85 0.010
regulation of reproductive process GO:2000241 66 0.010
regeneration GO:0031099 4 0.010
secretion GO:0046903 147 0.010
purine nucleoside monophosphate metabolic process GO:0009126 43 0.010
adult behavior GO:0030534 3 0.010
Fly
heterocycle biosynthetic process GO:0018130 187 0.010
Mouse
regulation of cell cycle process GO:0010564 145 0.010
secretion by cell GO:0032940 138 0.010
negative regulation of response to stimulus GO:0048585 73 0.010
response to bacterium GO:0009617 86 0.010
neuron projection guidance GO:0097485 82 0.010
neuron projection extension GO:1990138 37 0.010
regulation of ras protein signal transduction GO:0046578 41 0.010

mel-46 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.012