Caenorhabditis elegans

25 known processes

his-50 (CELE_F07B7.9)

Protein HIS-50

his-50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 170 0.942
Yeast
reproductive system development GO:0061458 850 0.938
gonad development GO:0008406 840 0.912
genitalia development GO:0048806 741 0.888
pharynx development GO:0060465 51 0.885
Worm
reproductive structure development GO:0048608 850 0.875
hermaphrodite genitalia development GO:0040035 734 0.864
embryo development GO:0009790 3052 0.863
development of primary sexual characteristics GO:0045137 840 0.861
embryo development ending in birth or egg hatching GO:0009792 2992 0.858
digestive tract development GO:0048565 122 0.848
Worm
digestive system development GO:0055123 122 0.842
Worm
developmental process involved in reproduction GO:0003006 1165 0.784
sex differentiation GO:0007548 909 0.766
single organism reproductive process GO:0044702 1196 0.760
organ development GO:0048513 1102 0.697
post embryonic development GO:0009791 2152 0.679
tube development GO:0035295 126 0.634
Worm
locomotion GO:0040011 1634 0.630
Worm
defense response GO:0006952 296 0.572
Worm
multicellular organism reproduction GO:0032504 819 0.568
meiotic cell cycle GO:0051321 335 0.564
Yeast
regulation of rna biosynthetic process GO:2001141 165 0.551
Yeast Worm
multi organism reproductive process GO:0044703 867 0.543
Yeast
cellular macromolecule biosynthetic process GO:0034645 247 0.524
Yeast Worm
sexual reproduction GO:0019953 546 0.506
Yeast
negative regulation of gene expression epigenetic GO:0045814 2 0.476
Yeast
negative regulation of transcription dna templated GO:0045892 53 0.472
Yeast
multicellular organismal reproductive behavior GO:0033057 384 0.465
macromolecule biosynthetic process GO:0009059 250 0.461
Yeast Worm
oviposition GO:0018991 364 0.458
histone modification GO:0016570 30 0.450
Yeast
multicellular organismal reproductive process GO:0048609 815 0.437
rna biosynthetic process GO:0032774 169 0.435
Yeast Worm
innate immune response GO:0045087 190 0.426
gene expression GO:0010467 412 0.417
Yeast Worm
nucleobase containing compound biosynthetic process GO:0034654 184 0.397
Yeast Worm
gene silencing GO:0016458 143 0.370
Yeast
organelle organization GO:0006996 783 0.369
Yeast Worm
cell cycle GO:0007049 526 0.369
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 102 0.365
Worm
transcription dna templated GO:0006351 168 0.361
Yeast Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.360
Yeast Worm
negative regulation of biological process GO:0048519 567 0.350
Yeast
receptor mediated endocytosis GO:0006898 715 0.349
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.340
Yeast Worm
regulation of gene expression GO:0010468 366 0.331
Yeast Worm
regulation of macromolecule metabolic process GO:0060255 421 0.328
Yeast Worm
organic substance biosynthetic process GO:1901576 323 0.322
Yeast Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.319
Yeast Worm
regulation of macromolecule biosynthetic process GO:0010556 189 0.315
Yeast Worm
cellular localization GO:0051641 360 0.290
Worm
transport GO:0006810 1093 0.279
Worm
regulation of nitrogen compound metabolic process GO:0051171 222 0.270
Yeast Worm
negative regulation of metabolic process GO:0009892 240 0.260
Yeast
regulation of gene expression epigenetic GO:0040029 163 0.258
Yeast
establishment of localization GO:0051234 1171 0.255
Worm
nucleic acid metabolic process GO:0090304 299 0.255
Yeast Worm
positive regulation of gene expression GO:0010628 112 0.249
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.239
Yeast Worm
biosynthetic process GO:0009058 323 0.238
Yeast Worm
vesicle mediated transport GO:0016192 852 0.232
Worm
aromatic compound biosynthetic process GO:0019438 192 0.229
Yeast Worm
multi organism behavior GO:0051705 389 0.225
negative regulation of macromolecule metabolic process GO:0010605 229 0.224
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.224
Yeast Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.223
Yeast Worm
cell cycle process GO:0022402 482 0.223
Yeast
covalent chromatin modification GO:0016569 30 0.221
Yeast
single organism localization GO:1902578 518 0.216
Worm
regulation of transcription dna templated GO:0006355 164 0.213
Yeast Worm
regulation of cellular biosynthetic process GO:0031326 189 0.209
Yeast Worm
regulation of rna metabolic process GO:0051252 173 0.207
Yeast Worm
negative regulation of cellular process GO:0048523 239 0.206
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 250 0.203
Yeast Worm
chromatin assembly or disassembly GO:0006333 1 0.196
regulation of nucleic acid templated transcription GO:1903506 165 0.196
Yeast Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.182
Yeast
establishment of localization in cell GO:0051649 318 0.182
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.182
Worm
negative regulation of gene expression GO:0010629 217 0.178
Yeast
nucleic acid templated transcription GO:0097659 169 0.177
Yeast Worm
endocytosis GO:0006897 819 0.174
Worm
nucleobase containing compound metabolic process GO:0006139 406 0.170
Yeast Worm
protein metabolic process GO:0019538 422 0.170
Yeast
heterocycle biosynthetic process GO:0018130 187 0.169
Yeast Worm
apoptotic process GO:0006915 478 0.165
secretion GO:0046903 147 0.165
Worm
regulation of biosynthetic process GO:0009889 189 0.164
Yeast Worm
positive regulation of metabolic process GO:0009893 187 0.161
Worm
multi organism reproductive behavior GO:0044705 387 0.161
regulation of cellular metabolic process GO:0031323 305 0.160
Yeast Worm
single organism transport GO:0044765 447 0.155
Worm
cell development GO:0048468 696 0.154
Worm
positive regulation of cellular process GO:0048522 332 0.151
Worm
regulation of primary metabolic process GO:0080090 292 0.151
Yeast Worm
chromatin modification GO:0016568 32 0.149
Yeast
macromolecular complex subunit organization GO:0043933 320 0.147
Yeast Worm
muscle cell differentiation GO:0042692 171 0.144
Worm
body morphogenesis GO:0010171 620 0.144
Worm
positive regulation of rna biosynthetic process GO:1902680 102 0.144
Worm
cellular protein complex assembly GO:0043623 178 0.143
Worm
positive regulation of macromolecule metabolic process GO:0010604 149 0.143
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.142
Yeast
positive regulation of cellular biosynthetic process GO:0031328 109 0.139
Worm
dna repair GO:0006281 23 0.139
chromosome organization GO:0051276 104 0.139
Yeast
secretion by cell GO:0032940 138 0.136
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.135
Worm
cellular component assembly GO:0022607 293 0.135
Worm
determination of adult lifespan GO:0008340 812 0.134
regulation of biological quality GO:0065008 741 0.134
Worm
regulation of metabolic process GO:0019222 478 0.131
Yeast Worm
macromolecule localization GO:0033036 771 0.129
Worm
cellular protein modification process GO:0006464 207 0.127
Yeast
cellular component assembly involved in morphogenesis GO:0010927 183 0.126
Worm
cytoskeleton organization GO:0007010 339 0.125
Worm
cellular component morphogenesis GO:0032989 318 0.123
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.117
Worm
rna metabolic process GO:0016070 228 0.117
Yeast Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.116
Worm
protein complex subunit organization GO:0071822 280 0.114
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.114
Yeast
cellular biosynthetic process GO:0044249 315 0.113
Yeast Worm
cellular response to dna damage stimulus GO:0006974 41 0.112
behavior GO:0007610 527 0.109
gamete generation GO:0007276 461 0.108
cellular protein metabolic process GO:0044267 279 0.106
Yeast
positive regulation of rna metabolic process GO:0051254 103 0.104
Worm
actomyosin structure organization GO:0031032 154 0.101
Worm
organelle assembly GO:0070925 214 0.101
Worm
multi multicellular organism process GO:0044706 390 0.100
muscle cell development GO:0055001 158 0.100
Worm
macromolecule modification GO:0043412 218 0.099
Yeast
actin filament based process GO:0030029 191 0.098
Worm
cellular component biogenesis GO:0044085 297 0.096
Worm
lipid localization GO:0010876 573 0.096
Worm
actin cytoskeleton organization GO:0030036 184 0.095
Worm
positive regulation of cellular metabolic process GO:0031325 178 0.094
Worm
single organism organelle organization GO:1902589 501 0.091
Yeast Worm
protein complex assembly GO:0006461 186 0.089
Worm
negative regulation of cellular metabolic process GO:0031324 95 0.088
Yeast
dna metabolic process GO:0006259 74 0.088
reproductive behavior GO:0019098 387 0.088
positive regulation of biosynthetic process GO:0009891 109 0.087
Worm
striated muscle cell development GO:0055002 157 0.087
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.087
muscle structure development GO:0061061 191 0.085
Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.083
Yeast
multicellular organismal aging GO:0010259 812 0.083
germ cell development GO:0007281 351 0.081
maintenance of location GO:0051235 580 0.081
Worm
striated muscle cell differentiation GO:0051146 158 0.078
Worm
cell death GO:0008219 547 0.078
fertilization GO:0009566 63 0.077
lipid storage GO:0019915 565 0.077
Worm
aging GO:0007568 812 0.074
negative regulation of biosynthetic process GO:0009890 65 0.074
Yeast
negative regulation of cellular biosynthetic process GO:0031327 65 0.073
Yeast
negative regulation of rna biosynthetic process GO:1902679 53 0.072
Yeast
chromatin organization GO:0006325 32 0.071
Yeast
myofibril assembly GO:0030239 154 0.070
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.070
Yeast
striated muscle myosin thick filament assembly GO:0071688 138 0.069
Worm
cellular macromolecular complex assembly GO:0034622 184 0.068
Worm
negative regulation of nucleic acid templated transcription GO:1903507 53 0.067
Yeast
macromolecular complex assembly GO:0065003 193 0.067
Worm
death GO:0016265 547 0.066
protein modification process GO:0036211 207 0.066
Yeast
protein complex biogenesis GO:0070271 186 0.064
Worm
myosin filament assembly GO:0031034 138 0.063
Worm
negative regulation of rna metabolic process GO:0051253 53 0.060
Yeast
meiotic chromosome segregation GO:0045132 139 0.056
cell division GO:0051301 262 0.054
defense response to bacterium GO:0042742 86 0.051
myosin filament organization GO:0031033 138 0.050
Worm
meiotic nuclear division GO:0007126 300 0.048
oogenesis GO:0048477 229 0.048
female gamete generation GO:0007292 254 0.048
pronuclear migration GO:0035046 51 0.045
inductive cell migration GO:0040039 145 0.041
single fertilization GO:0007338 61 0.035
vulval development GO:0040025 333 0.035
organelle fission GO:0048285 363 0.032
regulation of multicellular organism growth GO:0040014 373 0.031
programmed cell death GO:0012501 500 0.031
regulation of cell cycle GO:0051726 194 0.031
regulation of cellular component organization GO:0051128 248 0.030
regulation of meiotic cell cycle GO:0051445 136 0.029
positive regulation of developmental growth GO:0048639 354 0.029
multicellular organism growth GO:0035264 385 0.028
oocyte axis specification GO:0007309 2 0.027
defense response to other organism GO:0098542 100 0.026
regulation of cell division GO:0051302 142 0.026
regulation of vulval development GO:0040028 248 0.026
positive regulation of multicellular organism growth GO:0040018 352 0.025
growth GO:0040007 562 0.024
molting cycle GO:0042303 281 0.024
nucleus organization GO:0006997 38 0.024
regulation of multicellular organismal process GO:0051239 726 0.023
regulation of multicellular organismal development GO:2000026 317 0.023
negative regulation of nematode larval development GO:0061064 208 0.022
defense response to gram negative bacterium GO:0050829 64 0.022
immune response GO:0006955 192 0.022
cellular response to stress GO:0033554 162 0.021
regulation of cell cycle process GO:0010564 145 0.021
mitotic cell cycle process GO:1903047 194 0.021
regulation of developmental process GO:0050793 684 0.020
positive regulation of growth GO:0045927 369 0.020
cell motility GO:0048870 313 0.019
regulation of organelle organization GO:0033043 164 0.019
macromolecule catabolic process GO:0009057 202 0.019
oocyte construction GO:0007308 2 0.019
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.019
phagocytosis GO:0006909 115 0.019
developmental growth GO:0048589 412 0.018
positive regulation of transcription dna templated GO:0045893 102 0.018
Worm
microtubule based process GO:0007017 182 0.018
regulation of developmental growth GO:0048638 389 0.018
sensory organ morphogenesis GO:0090596 2 0.017
positive regulation of developmental process GO:0051094 408 0.017
protein catabolic process GO:0030163 162 0.017
negative regulation of post embryonic development GO:0048581 208 0.017
cell migration GO:0016477 306 0.016
negative regulation of vulval development GO:0040027 206 0.016
single organism catabolic process GO:0044712 129 0.015
regulation of nematode larval development GO:0061062 260 0.015
regulation of post embryonic development GO:0048580 260 0.015
response to external stimulus GO:0009605 289 0.014
chromosome segregation GO:0007059 180 0.014
oocyte differentiation GO:0009994 45 0.014
response to biotic stimulus GO:0009607 101 0.014
neuromuscular junction development GO:0007528 2 0.014
rna interference GO:0016246 137 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
posttranscriptional gene silencing by rna GO:0035194 143 0.014
spindle organization GO:0007051 92 0.014
posttranscriptional gene silencing GO:0016441 143 0.013
phagocytosis engulfment GO:0006911 98 0.013
oocyte development GO:0048599 44 0.013
response to wounding GO:0009611 4 0.013
regulation of growth GO:0040008 409 0.013
localization of cell GO:0051674 313 0.013
apoptotic cell clearance GO:0043277 111 0.013
regulation of nuclear division GO:0051783 115 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
filopodium assembly GO:0046847 2 0.013
gene silencing by rna GO:0031047 143 0.013
regulation of localization GO:0032879 194 0.013
ribonucleoside metabolic process GO:0009119 98 0.012
regulation of cell projection assembly GO:0060491 3 0.012
protein localization GO:0008104 205 0.012
protein oligomerization GO:0051259 4 0.012
negative regulation of developmental process GO:0051093 227 0.012
response to bacterium GO:0009617 86 0.012
regulation of protein targeting GO:1903533 3 0.012
response to external biotic stimulus GO:0043207 101 0.012
phosphorus metabolic process GO:0006793 232 0.011
skeletal muscle organ development GO:0060538 3 0.011
regulation of filopodium assembly GO:0051489 2 0.011
membrane invagination GO:0010324 98 0.011
cellular component movement GO:0006928 388 0.011
purine containing compound metabolic process GO:0072521 95 0.011
regulation of synapse assembly GO:0051963 2 0.010
catabolic process GO:0009056 318 0.010
regulation of cytoplasmic transport GO:1903649 3 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
negative regulation of multicellular organismal process GO:0051241 236 0.010
organic substance transport GO:0071702 113 0.010

his-50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of metabolism DOID:0014667 0 0.012