Caenorhabditis elegans

121 known processes

hmp-2 (CELE_K05C4.6)

Protein HMP-2

hmp-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sex differentiation GO:0007548 909 0.797
Mouse Worm
reproductive system development GO:0061458 850 0.740
Mouse Worm
developmental process involved in reproduction GO:0003006 1165 0.722
Mouse Worm Fly
single organism reproductive process GO:0044702 1196 0.686
Mouse Worm Fly
genitalia development GO:0048806 741 0.680
Mouse Worm
organ development GO:0048513 1102 0.581
Human Zebrafish Mouse Worm Fly
gonad development GO:0008406 840 0.577
Worm
vulval development GO:0040025 333 0.574
Worm
embryo development GO:0009790 3052 0.553
development of primary sexual characteristics GO:0045137 840 0.539
Worm
regulation of vulval development GO:0040028 248 0.492
Worm
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.485
Mouse Fly
multicellular organism reproduction GO:0032504 819 0.470
Mouse Worm Fly
locomotion GO:0040011 1634 0.468
regulation of nematode larval development GO:0061062 260 0.428
Worm
establishment of localization GO:0051234 1171 0.426
multicellular organismal reproductive process GO:0048609 815 0.382
Mouse Worm Fly
negative regulation of biological process GO:0048519 567 0.378
Human Mouse Worm Fly
regulation of response to stimulus GO:0048583 243 0.372
Mouse
cell death GO:0008219 547 0.366
Human Mouse Fly
regulation of multicellular organismal process GO:0051239 726 0.339
Human Mouse Worm Fly
cell migration GO:0016477 306 0.336
hermaphrodite genitalia development GO:0040035 734 0.326
Worm
germ cell development GO:0007281 351 0.325
Mouse Fly
signaling GO:0023052 401 0.297
Human Mouse Worm Fly
cell surface receptor signaling pathway GO:0007166 149 0.278
Human Mouse Worm Fly
negative regulation of vulval development GO:0040027 206 0.278
regulation of developmental process GO:0050793 684 0.277
Human Mouse Worm Fly
post embryonic organ development GO:0048569 336 0.259
Worm Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.255
negative regulation of post embryonic development GO:0048581 208 0.244
cell motility GO:0048870 313 0.240
transport GO:0006810 1093 0.217
generation of neurons GO:0048699 235 0.214
Mouse Fly
post embryonic development GO:0009791 2152 0.210
Worm Fly
vesicle mediated transport GO:0016192 852 0.177
determination of adult lifespan GO:0008340 812 0.163
sexual reproduction GO:0019953 546 0.157
Mouse Worm Fly
positive regulation of rna metabolic process GO:0051254 103 0.154
reproductive structure development GO:0048608 850 0.153
Mouse Worm
regulation of gene expression GO:0010468 366 0.144
multicellular organismal aging GO:0010259 812 0.128
positive regulation of gene expression GO:0010628 112 0.126
single organism signaling GO:0044700 401 0.125
Human Mouse Worm Fly
signal transduction GO:0007165 317 0.124
Human Mouse Worm Fly
macromolecule biosynthetic process GO:0009059 250 0.123
cell cycle GO:0007049 526 0.123
Human Mouse Worm
gamete generation GO:0007276 461 0.122
Mouse Fly
multicellular organismal reproductive behavior GO:0033057 384 0.119
Worm
regulation of rna biosynthetic process GO:2001141 165 0.116
embryo development ending in birth or egg hatching GO:0009792 2992 0.115
death GO:0016265 547 0.112
Human Mouse Fly
negative regulation of multicellular organismal process GO:0051241 236 0.108
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.108
aging GO:0007568 812 0.108
protein metabolic process GO:0019538 422 0.105
Human Worm
tissue development GO:0009888 112 0.102
Human Zebrafish Mouse Worm Fly
positive regulation of vulval development GO:0040026 52 0.101
Worm
body morphogenesis GO:0010171 620 0.094
neuron differentiation GO:0030182 217 0.093
Fly
regulation of post embryonic development GO:0048580 260 0.092
Worm
inductive cell migration GO:0040039 145 0.089
single organism localization GO:1902578 518 0.088
Human Mouse Fly
regulation of biological quality GO:0065008 741 0.088
Mouse Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.087
Human Mouse
apoptotic process GO:0006915 478 0.086
Human Mouse
cell morphogenesis GO:0000902 163 0.085
Human Mouse Fly
organ morphogenesis GO:0009887 67 0.085
Mouse Fly
receptor mediated endocytosis GO:0006898 715 0.084
organelle organization GO:0006996 783 0.083
positive regulation of cellular metabolic process GO:0031325 178 0.079
localization of cell GO:0051674 313 0.078
positive regulation of stem cell differentiation GO:2000738 1 0.077
Human
response to external stimulus GO:0009605 289 0.075
multi multicellular organism process GO:0044706 390 0.073
Worm
regulation of gene expression epigenetic GO:0040029 163 0.073
regulation of cell communication GO:0010646 176 0.072
Mouse Fly
negative regulation of nematode larval development GO:0061064 208 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.072
organic cyclic compound biosynthetic process GO:1901362 195 0.069
meiotic cell cycle GO:0051321 335 0.069
behavior GO:0007610 527 0.068
Worm Fly
positive regulation of developmental process GO:0051094 408 0.068
Human Mouse Worm Fly
lipid localization GO:0010876 573 0.068
specification of axis polarity GO:0065001 13 0.067
Worm
biosynthetic process GO:0009058 323 0.067
macromolecule localization GO:0033036 771 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.065
cell development GO:0048468 696 0.062
Human Mouse Fly
intracellular signal transduction GO:0035556 96 0.062
Mouse Worm
lipid storage GO:0019915 565 0.062
maintenance of location GO:0051235 580 0.061
regulation of nitrogen compound metabolic process GO:0051171 222 0.060
sensory organ morphogenesis GO:0090596 2 0.059
Mouse Fly
single organism transport GO:0044765 447 0.058
Human Mouse
negative regulation of response to stimulus GO:0048585 73 0.058
Mouse
cytoskeleton organization GO:0007010 339 0.056
regulation of locomotion GO:0040012 161 0.055
Worm
chromatin remodeling GO:0006338 2 0.054
heterocycle biosynthetic process GO:0018130 187 0.054
growth GO:0040007 562 0.054
Fly
negative regulation of gene expression epigenetic GO:0045814 2 0.054
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.053
gene silencing GO:0016458 143 0.053
cellular nitrogen compound biosynthetic process GO:0044271 192 0.052
anatomical structure formation involved in morphogenesis GO:0048646 250 0.052
Mouse Worm Fly
cell division GO:0051301 262 0.051
negative regulation of cellular process GO:0048523 239 0.051
Human Mouse Fly
organic substance biosynthetic process GO:1901576 323 0.051
regulation of macromolecule metabolic process GO:0060255 421 0.050
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.050
regionalization GO:0003002 31 0.050
Zebrafish Mouse Worm Fly
positive regulation of cellular process GO:0048522 332 0.050
regulation of multicellular organismal development GO:2000026 317 0.049
Human Mouse Worm Fly
regulation of cellular metabolic process GO:0031323 305 0.048
meiotic nuclear division GO:0007126 300 0.047
regulation of metabolic process GO:0019222 478 0.045
endocytosis GO:0006897 819 0.045
cellular biosynthetic process GO:0044249 315 0.045
canonical wnt signaling pathway GO:0060070 3 0.044
Human Mouse Fly
phosphorus metabolic process GO:0006793 232 0.043
Mouse Worm
gene expression GO:0010467 412 0.042
posttranscriptional gene silencing GO:0016441 143 0.042
developmental growth GO:0048589 412 0.041
Fly
cell cycle process GO:0022402 482 0.041
Human Mouse Worm
multi organism reproductive process GO:0044703 867 0.039
Mouse Worm Fly
oogenesis GO:0048477 229 0.038
Mouse Fly
neuron development GO:0048666 199 0.038
negative regulation of metabolic process GO:0009892 240 0.037
Human Mouse
regulation of cell fate commitment GO:0010453 22 0.037
Worm Fly
regulation of multicellular organism growth GO:0040014 373 0.037
regulation of macromolecule biosynthetic process GO:0010556 189 0.037
macromolecule modification GO:0043412 218 0.036
Human Worm
positive regulation of multicellular organism growth GO:0040018 352 0.036
programmed cell death GO:0012501 500 0.036
Human Mouse Fly
regulation of cellular component movement GO:0051270 62 0.035
Worm
multi organism behavior GO:0051705 389 0.035
Worm
oviposition GO:0018991 364 0.035
Worm
intracellular transport GO:0046907 77 0.035
cellular response to stress GO:0033554 162 0.034
axon development GO:0061564 163 0.034
regulation of cell migration GO:0030334 55 0.034
Worm
regulation of neurogenesis GO:0050767 40 0.034
Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.034
regulation of cell motility GO:2000145 57 0.034
Worm
regulation of transcription dna templated GO:0006355 164 0.034
positive regulation of developmental growth GO:0048639 354 0.033
cellular component morphogenesis GO:0032989 318 0.033
Human Mouse Fly
reproductive behavior GO:0019098 387 0.033
Worm
cuticle development GO:0042335 100 0.032
Fly
multi organism reproductive behavior GO:0044705 387 0.031
Worm
transcription dna templated GO:0006351 168 0.031
cellular component biogenesis GO:0044085 297 0.031
Human Fly
regulation of signaling GO:0023051 172 0.031
Mouse Fly
negative regulation of developmental process GO:0051093 227 0.030
Mouse Fly
protein modification process GO:0036211 207 0.030
Human Worm
rna interference GO:0016246 137 0.030
regulation of primary metabolic process GO:0080090 292 0.029
protein oligomerization GO:0051259 4 0.029
head development GO:0060322 1 0.028
Mouse
female gamete generation GO:0007292 254 0.028
Mouse Fly
signal transduction by phosphorylation GO:0023014 31 0.028
Mouse
gene silencing by rna GO:0031047 143 0.027
protein complex assembly GO:0006461 186 0.027
positive regulation of growth GO:0045927 369 0.027
regulation of developmental growth GO:0048638 389 0.027
response to organic substance GO:0010033 131 0.026
Human Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.026
defense response to other organism GO:0098542 100 0.026
cellular localization GO:0051641 360 0.026
Human Mouse Fly
regulation of localization GO:0032879 194 0.026
male sex differentiation GO:0046661 86 0.026
Mouse
membrane organization GO:0061024 135 0.025
Fly
pattern specification process GO:0007389 59 0.025
Zebrafish Mouse Worm Fly
cellular protein modification process GO:0006464 207 0.025
Human Worm
positive regulation of response to stimulus GO:0048584 55 0.025
Mouse
small molecule metabolic process GO:0044281 186 0.025
Human
cell projection organization GO:0030030 231 0.025
regulation of meiotic cell cycle GO:0051445 136 0.025
posttranscriptional gene silencing by rna GO:0035194 143 0.024
taxis GO:0042330 128 0.024
positive regulation of transcription dna templated GO:0045893 102 0.024
response to wounding GO:0009611 4 0.024
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.023
Human
regulation of cellular component organization GO:0051128 248 0.023
ras protein signal transduction GO:0007265 31 0.023
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.022
neuron projection development GO:0031175 187 0.022
system process GO:0003008 136 0.022
Fly
dendrite development GO:0016358 42 0.022
regulation of cell cycle GO:0051726 194 0.022
Human Mouse
membrane invagination GO:0010324 98 0.022
neurogenesis GO:0022008 236 0.022
Mouse Fly
cell proliferation GO:0008283 116 0.022
Human Mouse Fly
regulation of catalytic activity GO:0050790 78 0.022
Mouse Worm
cellular component assembly involved in morphogenesis GO:0010927 183 0.021
neurological system process GO:0050877 53 0.021
Fly
cellular response to chemical stimulus GO:0070887 129 0.021
Human Mouse
tissue morphogenesis GO:0048729 65 0.021
Human Zebrafish Mouse Worm Fly
positive regulation of multicellular organismal process GO:0051240 417 0.020
Human Mouse Worm Fly
protein complex subunit organization GO:0071822 280 0.020
Worm
response to chemical GO:0042221 356 0.020
Human Mouse
cellular macromolecule localization GO:0070727 75 0.020
Human Mouse Fly
cellular protein metabolic process GO:0044267 279 0.020
Human Worm
negative regulation of signal transduction GO:0009968 60 0.019
Mouse
cellular protein complex assembly GO:0043623 178 0.019
cellular component movement GO:0006928 388 0.019
chemotaxis GO:0006935 120 0.019
phosphorylation GO:0016310 116 0.018
Mouse Worm
response to abiotic stimulus GO:0009628 152 0.018
regulation of cell proliferation GO:0042127 105 0.018
Human Mouse
dauer larval development GO:0040024 92 0.018
cell projection morphogenesis GO:0048858 148 0.018
single organism organelle organization GO:1902589 501 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.018
muscle cell development GO:0055001 158 0.018
positive regulation of signal transduction GO:0009967 40 0.018
Mouse
multicellular organism growth GO:0035264 385 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.017
dna templated transcription elongation GO:0006354 1 0.017
regulation of growth GO:0040008 409 0.017
actin cytoskeleton organization GO:0030036 184 0.017
cellular response to organic substance GO:0071310 119 0.017
Human Mouse
positive regulation of nucleic acid templated transcription GO:1903508 102 0.017
actin filament based process GO:0030029 191 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.016
positive regulation of metabolic process GO:0009893 187 0.016
positive regulation of phosphate metabolic process GO:0045937 56 0.016
Mouse Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.016
Mouse
organelle localization GO:0051640 127 0.016
Mouse
nucleic acid metabolic process GO:0090304 299 0.016
regulation of nucleic acid templated transcription GO:1903506 165 0.015
rna metabolic process GO:0016070 228 0.015
positive regulation of signaling GO:0023056 66 0.015
Mouse
establishment of localization in cell GO:0051649 318 0.015
Mouse
regulation of signal transduction GO:0009966 135 0.015
Mouse
wnt signaling pathway GO:0016055 27 0.015
Human Mouse Worm Fly
mapk cascade GO:0000165 31 0.015
Mouse
regulation of biosynthetic process GO:0009889 189 0.014
regulation of cell cell adhesion GO:0022407 1 0.014
Fly
regeneration GO:0031099 4 0.014
small gtpase mediated signal transduction GO:0007264 32 0.014
Worm
cellular macromolecular complex assembly GO:0034622 184 0.014
apoptotic cell clearance GO:0043277 111 0.014
neuromuscular junction development GO:0007528 2 0.014
nucleobase containing compound biosynthetic process GO:0034654 184 0.014
organic substance transport GO:0071702 113 0.014
positive regulation of cellular biosynthetic process GO:0031328 109 0.014
response to endogenous stimulus GO:0009719 33 0.013
Human Mouse
negative regulation of gene expression GO:0010629 217 0.013
Human Mouse
positive regulation of nematode larval development GO:0061063 54 0.013
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
phosphate containing compound metabolic process GO:0006796 232 0.013
Mouse Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.013
striated muscle cell differentiation GO:0051146 158 0.013
oocyte development GO:0048599 44 0.013
Mouse
cell junction organization GO:0034330 18 0.013
Human Mouse Fly
negative regulation of protein metabolic process GO:0051248 27 0.013
Human
striated muscle myosin thick filament assembly GO:0071688 138 0.012
organophosphate metabolic process GO:0019637 125 0.012
striated muscle cell development GO:0055002 157 0.012
nucleobase containing compound metabolic process GO:0006139 406 0.012
cell fate commitment GO:0045165 139 0.012
Mouse Worm Fly
single organism behavior GO:0044708 83 0.012
Fly
organophosphate catabolic process GO:0046434 81 0.012
macromolecular complex assembly GO:0065003 193 0.012
response to unfolded protein GO:0006986 71 0.012
regulation of dna metabolic process GO:0051052 14 0.012
Mouse
negative regulation of cell communication GO:0010648 61 0.012
Mouse Fly
cellular component assembly GO:0022607 293 0.012
Human Fly
collagen and cuticulin based cuticle development GO:0040002 99 0.011
carbohydrate derivative metabolic process GO:1901135 141 0.011
Human
regulation of rna metabolic process GO:0051252 173 0.011
organism emergence from protective structure GO:0071684 48 0.011
cell part morphogenesis GO:0032990 152 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
purine ribonucleoside catabolic process GO:0046130 75 0.011
cell adhesion GO:0007155 21 0.011
neuron projection morphogenesis GO:0048812 114 0.011
macromolecular complex subunit organization GO:0043933 320 0.011
Worm
myosin filament assembly GO:0031034 138 0.011
regulation of kinase activity GO:0043549 29 0.011
Worm
negative regulation of signaling GO:0023057 61 0.011
Mouse Fly
regulation of protein modification process GO:0031399 46 0.011
Human Worm
neuron projection guidance GO:0097485 82 0.010
actomyosin structure organization GO:0031032 154 0.010
positive regulation of ligase activity GO:0051351 2 0.010
regulation of transport GO:0051049 91 0.010
Human
cell type specific apoptotic process GO:0097285 4 0.010
anterior posterior axis specification GO:0009948 17 0.010
Mouse
nervous system development GO:0007399 253 0.010
Mouse Fly
myosin filament organization GO:0031033 138 0.010
chromatin modification GO:0016568 32 0.010

hmp-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.018
disease of cellular proliferation DOID:14566 0 0.015
Human