Caenorhabditis elegans

26 known processes

pbs-5 (CELE_K05C4.1)

Protein PBS-5

pbs-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.942
embryo development GO:0009790 3052 0.860
pronuclear migration GO:0035046 51 0.808
single fertilization GO:0007338 61 0.789
post embryonic development GO:0009791 2152 0.714
locomotion GO:0040011 1634 0.664
sex differentiation GO:0007548 909 0.554
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.543
Yeast
fertilization GO:0009566 63 0.534
protein catabolic process GO:0030163 162 0.500
Yeast
catabolic process GO:0009056 318 0.448
Yeast
cellular protein catabolic process GO:0044257 37 0.428
Yeast
cell death GO:0008219 547 0.399
organic substance catabolic process GO:1901575 294 0.337
Yeast
ubiquitin dependent protein catabolic process GO:0006511 32 0.312
Yeast
establishment of localization GO:0051234 1171 0.312
cellular catabolic process GO:0044248 199 0.297
Yeast
mitotic cell cycle process GO:1903047 194 0.295
Fly
aging GO:0007568 812 0.292
sexual reproduction GO:0019953 546 0.290
single organism reproductive process GO:0044702 1196 0.283
multicellular organismal aging GO:0010259 812 0.276
proteasomal protein catabolic process GO:0010498 20 0.270
Yeast
multicellular organismal reproductive process GO:0048609 815 0.264
hermaphrodite genitalia development GO:0040035 734 0.262
transport GO:0006810 1093 0.258
gonad development GO:0008406 840 0.252
organ development GO:0048513 1102 0.250
modification dependent macromolecule catabolic process GO:0043632 32 0.250
Yeast
cellular protein metabolic process GO:0044267 279 0.247
Yeast
macromolecule catabolic process GO:0009057 202 0.246
Yeast
purine nucleoside catabolic process GO:0006152 75 0.239
reproductive system development GO:0061458 850 0.232
regulation of gene expression GO:0010468 366 0.221
multicellular organism reproduction GO:0032504 819 0.206
cellular response to stress GO:0033554 162 0.204
development of primary sexual characteristics GO:0045137 840 0.203
molting cycle GO:0042303 281 0.197
purine nucleotide metabolic process GO:0006163 95 0.196
regulation of macromolecule metabolic process GO:0060255 421 0.188
death GO:0016265 547 0.188
modification dependent protein catabolic process GO:0019941 32 0.186
Yeast
regulation of metabolic process GO:0019222 478 0.184
multi organism reproductive process GO:0044703 867 0.181
determination of adult lifespan GO:0008340 812 0.178
nucleus localization GO:0051647 55 0.177
programmed cell death GO:0012501 500 0.172
meiotic cell cycle process GO:1903046 170 0.162
developmental process involved in reproduction GO:0003006 1165 0.162
body morphogenesis GO:0010171 620 0.161
nuclear migration GO:0007097 54 0.154
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.144
Yeast
macromolecule localization GO:0033036 771 0.144
cell motility GO:0048870 313 0.143
generation of neurons GO:0048699 235 0.141
cellular localization GO:0051641 360 0.139
regulation of cellular metabolic process GO:0031323 305 0.135
gamete generation GO:0007276 461 0.134
cellular response to dna damage stimulus GO:0006974 41 0.134
endocytosis GO:0006897 819 0.131
negative regulation of biological process GO:0048519 567 0.130
protein modification process GO:0036211 207 0.125
apoptotic process GO:0006915 478 0.125
regulation of rna biosynthetic process GO:2001141 165 0.119
cell cycle process GO:0022402 482 0.115
Fly
protein complex subunit organization GO:0071822 280 0.114
Yeast Fly
proteolysis GO:0006508 61 0.114
Yeast
establishment of localization in cell GO:0051649 318 0.113
regulation of cellular biosynthetic process GO:0031326 189 0.113
cytoskeleton organization GO:0007010 339 0.112
Fly
regulation of transcription dna templated GO:0006355 164 0.107
growth GO:0040007 562 0.107
regulation of biological quality GO:0065008 741 0.107
purine containing compound metabolic process GO:0072521 95 0.106
regulation of macromolecule biosynthetic process GO:0010556 189 0.105
regulation of primary metabolic process GO:0080090 292 0.104
cell migration GO:0016477 306 0.099
spindle organization GO:0007051 92 0.099
Fly
vesicle mediated transport GO:0016192 852 0.097
multicellular organismal reproductive behavior GO:0033057 384 0.097
cell cycle GO:0007049 526 0.096
Fly
phosphorus metabolic process GO:0006793 232 0.096
establishment of nucleus localization GO:0040023 55 0.095
regulation of multicellular organismal process GO:0051239 726 0.095
receptor mediated endocytosis GO:0006898 715 0.095
genitalia development GO:0048806 741 0.092
neurogenesis GO:0022008 236 0.090
Fly
cell development GO:0048468 696 0.086
regulation of growth GO:0040008 409 0.084
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.084
purine nucleoside metabolic process GO:0042278 92 0.083
establishment of organelle localization GO:0051656 123 0.083
regulation of rna metabolic process GO:0051252 173 0.080
nucleobase containing compound metabolic process GO:0006139 406 0.079
protein metabolic process GO:0019538 422 0.079
Yeast
organonitrogen compound metabolic process GO:1901564 151 0.079
organelle organization GO:0006996 783 0.078
Fly
reproductive structure development GO:0048608 850 0.077
spindle assembly GO:0051225 8 0.075
purine nucleoside triphosphate catabolic process GO:0009146 72 0.074
positive regulation of nucleic acid templated transcription GO:1903508 102 0.074
nucleoside phosphate catabolic process GO:1901292 77 0.074
heterocycle biosynthetic process GO:0018130 187 0.073
single organism localization GO:1902578 518 0.073
aromatic compound biosynthetic process GO:0019438 192 0.071
cellular component morphogenesis GO:0032989 318 0.071
nervous system development GO:0007399 253 0.071
Fly
positive regulation of rna metabolic process GO:0051254 103 0.071
positive regulation of transcription dna templated GO:0045893 102 0.071
proteasome assembly GO:0043248 1 0.071
Yeast
maintenance of location GO:0051235 580 0.070
axon development GO:0061564 163 0.070
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.069
lipid localization GO:0010876 573 0.069
developmental growth GO:0048589 412 0.069
regulation of multicellular organism growth GO:0040014 373 0.068
positive regulation of developmental process GO:0051094 408 0.068
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.068
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.068
meiotic cell cycle GO:0051321 335 0.068
cellular macromolecule catabolic process GO:0044265 73 0.068
Yeast
macromolecular complex subunit organization GO:0043933 320 0.067
Yeast Fly
vulval development GO:0040025 333 0.066
negative regulation of cellular process GO:0048523 239 0.065
cellular protein modification process GO:0006464 207 0.064
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.064
negative regulation of vulval development GO:0040027 206 0.063
biosynthetic process GO:0009058 323 0.063
single organism intracellular transport GO:1902582 70 0.063
sensory organ morphogenesis GO:0090596 2 0.062
lipid storage GO:0019915 565 0.062
centrosomal and pronuclear rotation GO:0035047 6 0.061
ribonucleoside triphosphate metabolic process GO:0009199 87 0.061
positive regulation of cellular metabolic process GO:0031325 178 0.060
macromolecule biosynthetic process GO:0009059 250 0.058
phagocytosis GO:0006909 115 0.058
mitotic nuclear division GO:0007067 89 0.058
positive regulation of multicellular organism growth GO:0040018 352 0.058
germ cell development GO:0007281 351 0.057
cellular nitrogen compound biosynthetic process GO:0044271 192 0.057
head development GO:0060322 1 0.057
nucleotide metabolic process GO:0009117 108 0.056
purine ribonucleoside metabolic process GO:0046128 92 0.056
posttranscriptional regulation of gene expression GO:0010608 166 0.055
multicellular organism growth GO:0035264 385 0.055
regulation of developmental process GO:0050793 684 0.055
behavior GO:0007610 527 0.054
positive regulation of developmental growth GO:0048639 354 0.054
small molecule metabolic process GO:0044281 186 0.054
neuron development GO:0048666 199 0.054
regulation of vulval development GO:0040028 248 0.054
rna metabolic process GO:0016070 228 0.054
organelle localization GO:0051640 127 0.053
neuron projection development GO:0031175 187 0.053
response to wounding GO:0009611 4 0.053
response to external stimulus GO:0009605 289 0.051
ribonucleoside monophosphate metabolic process GO:0009161 45 0.051
multi organism behavior GO:0051705 389 0.051
protein localization GO:0008104 205 0.050
glycosyl compound metabolic process GO:1901657 100 0.050
nucleotide catabolic process GO:0009166 77 0.050
microtubule based process GO:0007017 182 0.050
Fly
cellular biosynthetic process GO:0044249 315 0.050
purine nucleoside triphosphate metabolic process GO:0009144 87 0.049
transcription from rna polymerase ii promoter GO:0006366 149 0.049
organic substance biosynthetic process GO:1901576 323 0.049
regulation of biosynthetic process GO:0009889 189 0.048
regulation of molecular function GO:0065009 89 0.048
cellular macromolecule biosynthetic process GO:0034645 247 0.048
single organism catabolic process GO:0044712 129 0.048
organophosphate catabolic process GO:0046434 81 0.048
negative regulation of nematode larval development GO:0061064 208 0.047
er associated ubiquitin dependent protein catabolic process GO:0030433 6 0.047
neuron differentiation GO:0030182 217 0.046
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.046
regulation of developmental growth GO:0048638 389 0.046
ribonucleoside catabolic process GO:0042454 77 0.046
intracellular transport GO:0046907 77 0.046
phosphate containing compound metabolic process GO:0006796 232 0.046
regulation of signal transduction GO:0009966 135 0.045
macromolecule modification GO:0043412 218 0.045
organophosphate metabolic process GO:0019637 125 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.044
cellular component movement GO:0006928 388 0.044
regulation of nitrogen compound metabolic process GO:0051171 222 0.044
nucleoside phosphate metabolic process GO:0006753 108 0.043
inductive cell migration GO:0040039 145 0.042
multi organism reproductive behavior GO:0044705 387 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.042
regulation of cellular component organization GO:0051128 248 0.042
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.042
negative regulation of gene expression GO:0010629 217 0.041
negative regulation of developmental process GO:0051093 227 0.041
ribonucleoside triphosphate catabolic process GO:0009203 72 0.040
localization of cell GO:0051674 313 0.039
spermatogenesis GO:0007283 41 0.038
cellular nitrogen compound catabolic process GO:0044270 119 0.038
nucleobase containing compound biosynthetic process GO:0034654 184 0.037
atp metabolic process GO:0046034 42 0.037
carbohydrate derivative catabolic process GO:1901136 82 0.037
male gamete generation GO:0048232 41 0.037
regulation of localization GO:0032879 194 0.037
nucleic acid templated transcription GO:0097659 169 0.037
rna biosynthetic process GO:0032774 169 0.037
gene silencing by rna GO:0031047 143 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.036
regulation of response to wounding GO:1903034 1 0.036
female gamete generation GO:0007292 254 0.036
regulation of nematode larval development GO:0061062 260 0.035
single organism transport GO:0044765 447 0.035
nucleoside catabolic process GO:0009164 78 0.035
regulation of catalytic activity GO:0050790 78 0.035
positive regulation of multicellular organismal process GO:0051240 417 0.034
cell division GO:0051301 262 0.034
ribonucleotide catabolic process GO:0009261 75 0.033
glycosyl compound catabolic process GO:1901658 79 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
regulation of nucleic acid templated transcription GO:1903506 165 0.033
macromolecular complex assembly GO:0065003 193 0.033
Yeast
organic cyclic compound biosynthetic process GO:1901362 195 0.033
heterocycle catabolic process GO:0046700 119 0.032
nucleobase containing compound catabolic process GO:0034655 114 0.032
cellular component biogenesis GO:0044085 297 0.032
Yeast
transcription dna templated GO:0006351 168 0.032
cellular protein localization GO:0034613 75 0.032
signaling GO:0023052 401 0.031
muscle tissue development GO:0060537 1 0.031
purine ribonucleotide metabolic process GO:0009150 95 0.031
organonitrogen compound catabolic process GO:1901565 90 0.031
oocyte construction GO:0007308 2 0.031
nucleoside metabolic process GO:0009116 99 0.031
organelle assembly GO:0070925 214 0.031
organic cyclic compound catabolic process GO:1901361 119 0.030
mitotic spindle organization GO:0007052 81 0.030
Fly
cell projection organization GO:0030030 231 0.030
oviposition GO:0018991 364 0.030
positive regulation of cell communication GO:0010647 69 0.030
oocyte axis specification GO:0007309 2 0.030
system process GO:0003008 136 0.030
nucleoside triphosphate catabolic process GO:0009143 72 0.029
regulation of locomotion GO:0040012 161 0.029
golgi vesicle transport GO:0048193 3 0.029
negative regulation of metabolic process GO:0009892 240 0.029
purine containing compound catabolic process GO:0072523 75 0.028
gene expression GO:0010467 412 0.028
purine ribonucleotide catabolic process GO:0009154 75 0.028
positive regulation of rna biosynthetic process GO:1902680 102 0.027
meiotic chromosome segregation GO:0045132 139 0.027
posttranscriptional gene silencing GO:0016441 143 0.027
autophagy GO:0006914 29 0.027
regulation of gene expression epigenetic GO:0040029 163 0.026
organelle fission GO:0048285 363 0.026
spindle assembly involved in mitosis GO:0090307 6 0.026
purine ribonucleoside catabolic process GO:0046130 75 0.026
protein complex assembly GO:0006461 186 0.026
Yeast
protein modification by small protein conjugation or removal GO:0070647 40 0.026
single organism carbohydrate metabolic process GO:0044723 29 0.025
posttranscriptional gene silencing by rna GO:0035194 143 0.025
secretion by cell GO:0032940 138 0.025
single organism organelle organization GO:1902589 501 0.025
Fly
regulation of cell motility GO:2000145 57 0.025
oogenesis GO:0048477 229 0.025
regulation of response to stimulus GO:0048583 243 0.025
nucleobase containing small molecule metabolic process GO:0055086 115 0.024
multi multicellular organism process GO:0044706 390 0.024
reproductive behavior GO:0019098 387 0.024
gene silencing GO:0016458 143 0.024
protein complex biogenesis GO:0070271 186 0.023
Yeast
anatomical structure formation involved in morphogenesis GO:0048646 250 0.023
positive regulation of neuron differentiation GO:0045666 4 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.023
negative regulation of post embryonic development GO:0048581 208 0.023
positive regulation of growth GO:0045927 369 0.023
purine nucleotide catabolic process GO:0006195 75 0.022
ribonucleotide metabolic process GO:0009259 99 0.022
post embryonic organ development GO:0048569 336 0.022
response to abiotic stimulus GO:0009628 152 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.022
ribose phosphate metabolic process GO:0019693 99 0.022
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
single organism signaling GO:0044700 401 0.021
cytokinesis GO:0000910 80 0.021
purine nucleoside monophosphate catabolic process GO:0009128 28 0.021
protein deubiquitination GO:0016579 2 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.021
muscle cell differentiation GO:0042692 171 0.021
atp catabolic process GO:0006200 27 0.020
rna interference GO:0016246 137 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.019
regulation of signaling GO:0023051 172 0.019
meiotic nuclear division GO:0007126 300 0.019
regulation of hydrolase activity GO:0051336 45 0.019
regulation of cell cycle GO:0051726 194 0.019
response to hermaphrodite contact GO:0034606 10 0.019
oxoacid metabolic process GO:0043436 47 0.019
establishment or maintenance of cell polarity GO:0007163 63 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.019
cellular component assembly GO:0022607 293 0.019
Yeast
aromatic compound catabolic process GO:0019439 116 0.019
nucleoside monophosphate metabolic process GO:0009123 46 0.019
dna templated transcription initiation GO:0006352 3 0.018
secretion GO:0046903 147 0.018
dna templated transcription elongation GO:0006354 1 0.018
negative regulation of response to external stimulus GO:0032102 3 0.018
chromosome segregation GO:0007059 180 0.018
intracellular signal transduction GO:0035556 96 0.018
signal transduction GO:0007165 317 0.018
organic substance transport GO:0071702 113 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
cellular macromolecular complex assembly GO:0034622 184 0.017
Yeast
axonogenesis GO:0007409 102 0.017
cytoskeleton dependent cytokinesis GO:0061640 35 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
tissue development GO:0009888 112 0.017
dauer larval development GO:0040024 92 0.017
positive regulation of molecular function GO:0044093 61 0.017
cellular protein complex assembly GO:0043623 178 0.017
Yeast
positive regulation of cell projection organization GO:0031346 4 0.016
nucleic acid metabolic process GO:0090304 299 0.016
regulation of cytoplasmic transport GO:1903649 3 0.016
taxis GO:0042330 128 0.016
chromosome organization GO:0051276 104 0.016
cell recognition GO:0008037 85 0.016
regulation of multicellular organismal development GO:2000026 317 0.016
axon guidance GO:0007411 82 0.016
carboxylic acid metabolic process GO:0019752 34 0.015
actin filament based process GO:0030029 191 0.015
positive regulation of chromosome organization GO:2001252 2 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.015
negative regulation of macromolecule metabolic process GO:0010605 229 0.015
organic acid metabolic process GO:0006082 47 0.015
striated muscle cell development GO:0055002 157 0.015
peptidyl amino acid modification GO:0018193 58 0.015
regeneration GO:0031099 4 0.014
regulation of phosphate metabolic process GO:0019220 81 0.014
positive regulation of neurogenesis GO:0050769 4 0.014
neuron projection guidance GO:0097485 82 0.014
carbohydrate metabolic process GO:0005975 34 0.014
regulation of cell communication GO:0010646 176 0.014
cell morphogenesis involved in differentiation GO:0000904 112 0.014
membrane organization GO:0061024 135 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
ribonucleoside metabolic process GO:0009119 98 0.013
covalent chromatin modification GO:0016569 30 0.013
purine nucleoside monophosphate metabolic process GO:0009126 43 0.013
ribonucleoside monophosphate catabolic process GO:0009158 28 0.013
positive regulation of cellular biosynthetic process GO:0031328 109 0.013
response to chemical GO:0042221 356 0.013
sodium ion transmembrane transport GO:0035725 8 0.013
positive regulation of metabolic process GO:0009893 187 0.013
negative regulation of cellular metabolic process GO:0031324 95 0.013
epithelial cell proliferation GO:0050673 1 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
endomembrane system organization GO:0010256 22 0.012
regulation of mitotic cell cycle GO:0007346 76 0.012
positive regulation of gene expression GO:0010628 112 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.012
positive regulation of cell migration GO:0030335 3 0.012
cellular macromolecule localization GO:0070727 75 0.012
pole plasm assembly GO:0007315 2 0.012
muscle cell development GO:0055001 158 0.012
myofibril assembly GO:0030239 154 0.012
positive regulation of cellular process GO:0048522 332 0.012
positive regulation of signaling GO:0023056 66 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.011
positive regulation of neuron projection development GO:0010976 4 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
cellular response to metal ion GO:0071248 3 0.011
regulation of nucleotide metabolic process GO:0006140 37 0.011
regulation of response to stress GO:0080134 28 0.011
regulation of cellular catabolic process GO:0031329 51 0.011
macromolecular complex disassembly GO:0032984 20 0.011
cellular response to topologically incorrect protein GO:0035967 76 0.011
regulation of protein stability GO:0031647 3 0.011
muscle structure development GO:0061061 191 0.011
canonical wnt signaling pathway GO:0060070 3 0.011
actomyosin structure organization GO:0031032 154 0.011
glycosylation GO:0070085 20 0.011
pharyngeal pumping GO:0043050 58 0.011
defense response to other organism GO:0098542 100 0.011
regulation of protein localization GO:0032880 50 0.011
neuron projection morphogenesis GO:0048812 114 0.011
skeletal muscle organ development GO:0060538 3 0.011
dna repair GO:0006281 23 0.011
establishment of protein localization GO:0045184 50 0.010
detection of abiotic stimulus GO:0009582 4 0.010
regulation of cell proliferation GO:0042127 105 0.010
regulation of protein targeting GO:1903533 3 0.010
regulation of chromatin modification GO:1903308 2 0.010
oxidation reduction process GO:0055114 59 0.010
negative regulation of cellular protein metabolic process GO:0032269 27 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
response to inorganic substance GO:0010035 50 0.010
translation GO:0006412 37 0.010

pbs-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
myopathy DOID:423 0 0.021
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.021
muscular dystrophy DOID:9884 0 0.011