Caenorhabditis elegans

98 known processes

sma-1 (CELE_R31.1)

Protein SMA-1

sma-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neurogenesis GO:0022008 236 0.824
Worm
vesicle mediated transport GO:0016192 852 0.680
Fly
transport GO:0006810 1093 0.657
Fly
cellular protein modification process GO:0006464 207 0.612
neuron projection development GO:0031175 187 0.564
Worm
neuron projection guidance GO:0097485 82 0.558
Worm
cell morphogenesis GO:0000902 163 0.549
Worm
cell development GO:0048468 696 0.543
cellular localization GO:0051641 360 0.532
Fly
embryo development ending in birth or egg hatching GO:0009792 2992 0.493
endocytosis GO:0006897 819 0.480
Fly
developmental process involved in reproduction GO:0003006 1165 0.475
macromolecule modification GO:0043412 218 0.454
signaling GO:0023052 401 0.385
intracellular signal transduction GO:0035556 96 0.381
multi organism reproductive process GO:0044703 867 0.379
regulation of response to stimulus GO:0048583 243 0.374
regulation of developmental process GO:0050793 684 0.368
embryo development GO:0009790 3052 0.360
locomotion GO:0040011 1634 0.352
receptor mediated endocytosis GO:0006898 715 0.342
single organism reproductive process GO:0044702 1196 0.340
cellular protein metabolic process GO:0044267 279 0.334
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.312
Worm
growth GO:0040007 562 0.311
regulation of multicellular organismal process GO:0051239 726 0.291
cell projection organization GO:0030030 231 0.287
Worm
establishment of localization GO:0051234 1171 0.284
Fly
generation of neurons GO:0048699 235 0.283
Worm
positive regulation of multicellular organismal process GO:0051240 417 0.283
programmed cell death GO:0012501 500 0.282
regulation of phosphate metabolic process GO:0019220 81 0.278
positive regulation of response to stimulus GO:0048584 55 0.276
sexual reproduction GO:0019953 546 0.264
neuron development GO:0048666 199 0.259
Worm
protein modification process GO:0036211 207 0.258
regulation of developmental growth GO:0048638 389 0.257
multicellular organism reproduction GO:0032504 819 0.253
single organism localization GO:1902578 518 0.249
Fly
phosphorylation GO:0016310 116 0.245
apoptotic process GO:0006915 478 0.245
cytoskeleton organization GO:0007010 339 0.244
response to external stimulus GO:0009605 289 0.242
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.240
negative regulation of multicellular organismal process GO:0051241 236 0.238
phosphate containing compound metabolic process GO:0006796 232 0.235
nervous system development GO:0007399 253 0.234
Worm
negative regulation of biological process GO:0048519 567 0.232
death GO:0016265 547 0.228
multicellular organismal reproductive process GO:0048609 815 0.225
single organism organelle organization GO:1902589 501 0.207
cell death GO:0008219 547 0.206
protein localization GO:0008104 205 0.200
regulation of cellular metabolic process GO:0031323 305 0.197
regulation of intracellular signal transduction GO:1902531 77 0.197
organ development GO:0048513 1102 0.192
organelle organization GO:0006996 783 0.191
regulation of multicellular organismal development GO:2000026 317 0.183
protein metabolic process GO:0019538 422 0.181
cellular component movement GO:0006928 388 0.181
Worm
positive regulation of developmental process GO:0051094 408 0.177
multi organism reproductive behavior GO:0044705 387 0.175
epithelium development GO:0060429 68 0.173
digestive tract development GO:0048565 122 0.167
protein phosphorylation GO:0006468 85 0.162
regulation of growth GO:0040008 409 0.162
positive regulation of cellular metabolic process GO:0031325 178 0.161
neuron projection morphogenesis GO:0048812 114 0.160
Worm
cell morphogenesis involved in differentiation GO:0000904 112 0.159
Worm
body morphogenesis GO:0010171 620 0.155
post embryonic development GO:0009791 2152 0.152
cell motility GO:0048870 313 0.152
behavior GO:0007610 527 0.151
multicellular organismal reproductive behavior GO:0033057 384 0.138
establishment of localization in cell GO:0051649 318 0.137
Fly
development of primary sexual characteristics GO:0045137 840 0.137
developmental growth GO:0048589 412 0.134
cellular component morphogenesis GO:0032989 318 0.131
single organism transport GO:0044765 447 0.131
Fly
tissue development GO:0009888 112 0.127
regulation of mapk cascade GO:0043408 23 0.127
cell cycle process GO:0022402 482 0.125
Fly
regulation of cellular component organization GO:0051128 248 0.125
nucleobase containing compound metabolic process GO:0006139 406 0.124
synaptic transmission GO:0007268 106 0.123
tube morphogenesis GO:0035239 79 0.123
regulation of cellular protein metabolic process GO:0032268 75 0.122
multi multicellular organism process GO:0044706 390 0.119
macromolecule localization GO:0033036 771 0.118
genitalia development GO:0048806 741 0.118
aging GO:0007568 812 0.116
Worm
cell migration GO:0016477 306 0.115
actin cytoskeleton organization GO:0030036 184 0.115
positive regulation of cell communication GO:0010647 69 0.114
regulation of metabolic process GO:0019222 478 0.113
regulation of cell communication GO:0010646 176 0.113
phosphorus metabolic process GO:0006793 232 0.111
sex differentiation GO:0007548 909 0.110
taxis GO:0042330 128 0.110
Worm
germ cell development GO:0007281 351 0.108
mapk cascade GO:0000165 31 0.106
cell cell signaling GO:0007267 118 0.105
signal transduction GO:0007165 317 0.104
regulation of actin filament based process GO:0032970 22 0.103
cell projection morphogenesis GO:0048858 148 0.100
Worm
positive regulation of metabolic process GO:0009893 187 0.098
positive regulation of signaling GO:0023056 66 0.097
rna metabolic process GO:0016070 228 0.097
multi organism behavior GO:0051705 389 0.097
regulation of primary metabolic process GO:0080090 292 0.094
neuron differentiation GO:0030182 217 0.094
Worm
regulation of biological quality GO:0065008 741 0.092
cellular component assembly GO:0022607 293 0.091
tube development GO:0035295 126 0.091
regulation of phosphorylation GO:0042325 45 0.090
system process GO:0003008 136 0.089
organic substance biosynthetic process GO:1901576 323 0.088
gamete generation GO:0007276 461 0.088
gene expression GO:0010467 412 0.086
head development GO:0060322 1 0.085
cellular component biogenesis GO:0044085 297 0.084
hermaphrodite genitalia development GO:0040035 734 0.084
protein complex assembly GO:0006461 186 0.083
positive regulation of developmental growth GO:0048639 354 0.082
determination of adult lifespan GO:0008340 812 0.082
Worm
signal transduction by phosphorylation GO:0023014 31 0.081
gonad development GO:0008406 840 0.080
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.079
cell cycle GO:0007049 526 0.079
Fly
organelle localization GO:0051640 127 0.079
reproductive system development GO:0061458 850 0.078
cell proliferation GO:0008283 116 0.077
gastrulation GO:0007369 58 0.076
regulation of nitrogen compound metabolic process GO:0051171 222 0.076
localization of cell GO:0051674 313 0.075
vulval development GO:0040025 333 0.072
cell part morphogenesis GO:0032990 152 0.072
Worm
axon development GO:0061564 163 0.069
Worm
regulation of hydrolase activity GO:0051336 45 0.068
regulation of localization GO:0032879 194 0.067
multicellular organismal aging GO:0010259 812 0.066
Worm
regulation of signaling GO:0023051 172 0.066
cellular macromolecule localization GO:0070727 75 0.066
reproductive behavior GO:0019098 387 0.066
maintenance of location GO:0051235 580 0.065
positive regulation of neuron differentiation GO:0045666 4 0.064
regulation of nematode larval development GO:0061062 260 0.063
reproductive structure development GO:0048608 850 0.063
single organism signaling GO:0044700 401 0.063
cellular response to stress GO:0033554 162 0.062
mating behavior GO:0007617 32 0.062
oviposition GO:0018991 364 0.061
regulation of macromolecule biosynthetic process GO:0010556 189 0.061
positive regulation of phosphorus metabolic process GO:0010562 56 0.061
negative regulation of vulval development GO:0040027 206 0.060
positive regulation of catalytic activity GO:0043085 59 0.060
mitotic cell cycle process GO:1903047 194 0.059
Fly
positive regulation of growth GO:0045927 369 0.058
negative regulation of developmental process GO:0051093 227 0.058
cellular nitrogen compound biosynthetic process GO:0044271 192 0.057
regulation of catalytic activity GO:0050790 78 0.057
positive regulation of multicellular organism growth GO:0040018 352 0.057
regulation of gene expression GO:0010468 366 0.057
digestive system development GO:0055123 122 0.057
secretion GO:0046903 147 0.057
peptidyl tyrosine phosphorylation GO:0018108 2 0.056
biological adhesion GO:0022610 21 0.056
positive regulation of phosphate metabolic process GO:0045937 56 0.055
aromatic compound biosynthetic process GO:0019438 192 0.055
regulation of molecular function GO:0065009 89 0.053
organic cyclic compound biosynthetic process GO:1901362 195 0.053
positive regulation of intracellular signal transduction GO:1902533 24 0.052
lipid storage GO:0019915 565 0.051
cellular biosynthetic process GO:0044249 315 0.051
lipid localization GO:0010876 573 0.050
biosynthetic process GO:0009058 323 0.050
epithelial tube morphogenesis GO:0060562 1 0.049
chemotaxis GO:0006935 120 0.049
Worm
female gamete generation GO:0007292 254 0.047
organ morphogenesis GO:0009887 67 0.046
cell recognition GO:0008037 85 0.046
Worm
response to abiotic stimulus GO:0009628 152 0.045
regulation of cell proliferation GO:0042127 105 0.044
regulation of response to stress GO:0080134 28 0.043
regulation of nervous system development GO:0051960 41 0.042
cellular catabolic process GO:0044248 199 0.041
protein complex subunit organization GO:0071822 280 0.041
regulation of signal transduction GO:0009966 135 0.041
regulation of post embryonic development GO:0048580 260 0.041
regulation of vulval development GO:0040028 248 0.040
meiotic cell cycle GO:0051321 335 0.040
regulation of multicellular organism growth GO:0040014 373 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.040
axon guidance GO:0007411 82 0.040
Worm
negative regulation of post embryonic development GO:0048581 208 0.040
protein complex biogenesis GO:0070271 186 0.039
embryonic morphogenesis GO:0048598 152 0.039
regulation of kinase activity GO:0043549 29 0.039
skeletal muscle organ development GO:0060538 3 0.039
rna biosynthetic process GO:0032774 169 0.038
nucleic acid metabolic process GO:0090304 299 0.037
dendrite development GO:0016358 42 0.037
Worm
establishment of organelle localization GO:0051656 123 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.037
multicellular organism growth GO:0035264 385 0.036
positive regulation of molecular function GO:0044093 61 0.036
regulation of biosynthetic process GO:0009889 189 0.035
regulation of organelle organization GO:0033043 164 0.034
endomembrane system organization GO:0010256 22 0.034
rna localization GO:0006403 3 0.034
cell adhesion GO:0007155 21 0.034
digestive tract morphogenesis GO:0048546 76 0.034
positive regulation of cellular process GO:0048522 332 0.033
nucleic acid templated transcription GO:0097659 169 0.033
nematode male tail tip morphogenesis GO:0045138 77 0.032
regulation of phosphorus metabolic process GO:0051174 81 0.032
regulation of locomotion GO:0040012 161 0.032
cell division GO:0051301 262 0.032
Fly
actin filament based process GO:0030029 191 0.032
oxoacid metabolic process GO:0043436 47 0.032
regulation of protein metabolic process GO:0051246 81 0.031
negative regulation of metabolic process GO:0009892 240 0.031
neuromuscular junction development GO:0007528 2 0.031
heterocycle biosynthetic process GO:0018130 187 0.031
response to wounding GO:0009611 4 0.031
Fly
inductive cell migration GO:0040039 145 0.031
microtubule based process GO:0007017 182 0.029
synaptic vesicle recycling GO:0036465 3 0.029
regulation of transport GO:0051049 91 0.029
regulation of cell motility GO:2000145 57 0.029
chromosome segregation GO:0007059 180 0.029
synapse organization GO:0050808 24 0.029
regulation of response to wounding GO:1903034 1 0.029
regulation of cell cycle process GO:0010564 145 0.028
macromolecule biosynthetic process GO:0009059 250 0.028
oocyte axis specification GO:0007309 2 0.028
macromolecular complex assembly GO:0065003 193 0.028
transcription dna templated GO:0006351 168 0.027
regulation of cell adhesion GO:0030155 6 0.027
positive regulation of signal transduction GO:0009967 40 0.027
regulation of cellular component biogenesis GO:0044087 26 0.027
cellular macromolecular complex assembly GO:0034622 184 0.027
neuromuscular process GO:0050905 1 0.027
response to chemical GO:0042221 356 0.026
Worm
transcription from rna polymerase ii promoter GO:0006366 149 0.026
positive regulation of hydrolase activity GO:0051345 38 0.026
macromolecular complex subunit organization GO:0043933 320 0.026
organic acid metabolic process GO:0006082 47 0.025
regulation of cellular biosynthetic process GO:0031326 189 0.025
negative regulation of cellular process GO:0048523 239 0.025
regulation of cell migration GO:0030334 55 0.025
regulation of protein localization GO:0032880 50 0.025
positive regulation of locomotion GO:0040017 42 0.025
muscle structure development GO:0061061 191 0.024
positive regulation of synaptic transmission GO:0050806 24 0.024
organelle fission GO:0048285 363 0.024
intracellular transport GO:0046907 77 0.024
Fly
oocyte construction GO:0007308 2 0.024
regulation of cell death GO:0010941 65 0.024
regulation of synapse assembly GO:0051963 2 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
mating GO:0007618 34 0.023
cellular protein complex assembly GO:0043623 178 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
nucleoside catabolic process GO:0009164 78 0.023
amine metabolic process GO:0009308 15 0.023
meiotic cell cycle process GO:1903046 170 0.023
regulation of rna metabolic process GO:0051252 173 0.022
cellular amine metabolic process GO:0044106 15 0.022
oogenesis GO:0048477 229 0.022
nucleobase containing compound biosynthetic process GO:0034654 184 0.022
organonitrogen compound metabolic process GO:1901564 151 0.022
negative regulation of response to stimulus GO:0048585 73 0.022
regulation of cellular catabolic process GO:0031329 51 0.022
establishment of cell polarity GO:0030010 46 0.022
single organism cellular localization GO:1902580 72 0.022
plasma membrane organization GO:0007009 9 0.022
dna templated transcription elongation GO:0006354 1 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
posttranscriptional regulation of gene expression GO:0010608 166 0.021
positive regulation of protein metabolic process GO:0051247 45 0.021
regulation of cell cycle GO:0051726 194 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.021
regulation of cell morphogenesis GO:0022604 40 0.021
small molecule metabolic process GO:0044281 186 0.021
single organism intracellular transport GO:1902582 70 0.021
Fly
excretion GO:0007588 49 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cellular amino acid metabolic process GO:0006520 15 0.021
establishment or maintenance of cell polarity GO:0007163 63 0.021
single organism catabolic process GO:0044712 129 0.021
cell surface receptor signaling pathway GO:0007166 149 0.020
cell projection assembly GO:0030031 35 0.020
regulation of cell differentiation GO:0045595 81 0.020
positive regulation of macromolecule metabolic process GO:0010604 149 0.020
anatomical structure formation involved in morphogenesis GO:0048646 250 0.020
regulation of neurogenesis GO:0050767 40 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.020
cellular protein localization GO:0034613 75 0.020
regulation of transferase activity GO:0051338 31 0.019
negative regulation of nematode larval development GO:0061064 208 0.019
response to organic substance GO:0010033 131 0.019
regulation of cell development GO:0060284 49 0.019
organic cyclic compound catabolic process GO:1901361 119 0.019
regulation of protein kinase activity GO:0045859 28 0.019
cell junction organization GO:0034330 18 0.019
intracellular receptor signaling pathway GO:0030522 2 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.019
carboxylic acid metabolic process GO:0019752 34 0.019
secretion by cell GO:0032940 138 0.019
cell substrate adhesion GO:0031589 1 0.018
male anatomical structure morphogenesis GO:0090598 78 0.018
purine ribonucleotide catabolic process GO:0009154 75 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
epithelial cell differentiation GO:0030855 17 0.017
regulation of catabolic process GO:0009894 57 0.017
response to oxygen containing compound GO:1901700 44 0.017
signal transduction involved in regulation of gene expression GO:0023019 1 0.017
male sex differentiation GO:0046661 86 0.017
negative regulation of signaling GO:0023057 61 0.017
positive regulation of phosphorylation GO:0042327 27 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
pattern specification process GO:0007389 59 0.017
meiotic cytokinesis GO:0033206 15 0.017
organic substance transport GO:0071702 113 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.016
immune response GO:0006955 192 0.016
muscle tissue development GO:0060537 1 0.016
positive regulation of mapk cascade GO:0043410 14 0.016
axonogenesis GO:0007409 102 0.016
Worm
striated muscle myosin thick filament assembly GO:0071688 138 0.016
cellular response to oxygen containing compound GO:1901701 21 0.016
positive regulation of rna metabolic process GO:0051254 103 0.016
regulation of cytoskeleton organization GO:0051493 41 0.015
myofibril assembly GO:0030239 154 0.015
ribonucleoside triphosphate metabolic process GO:0009199 87 0.015
organonitrogen compound catabolic process GO:1901565 90 0.015
defense response to other organism GO:0098542 100 0.015
erbb signaling pathway GO:0038127 9 0.015
axis specification GO:0009798 23 0.015
striated muscle cell development GO:0055002 157 0.014
filopodium assembly GO:0046847 2 0.014
regulation of neuron differentiation GO:0045664 40 0.014
meiotic chromosome segregation GO:0045132 139 0.014
regeneration GO:0031099 4 0.014
anterior posterior pattern specification GO:0009952 27 0.014
striated muscle cell differentiation GO:0051146 158 0.014
regulation of cellular response to stress GO:0080135 19 0.014
organic substance catabolic process GO:1901575 294 0.013
regulation of apoptotic process GO:0042981 36 0.013
organonitrogen compound biosynthetic process GO:1901566 44 0.013
peptidyl amino acid modification GO:0018193 58 0.013
epithelial cell proliferation GO:0050673 1 0.013
muscle cell development GO:0055001 158 0.013
negative regulation of cell communication GO:0010648 61 0.013
organelle assembly GO:0070925 214 0.013
peptidyl tyrosine modification GO:0018212 3 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
cellular ketone metabolic process GO:0042180 14 0.013
negative regulation of macromolecule metabolic process GO:0010605 229 0.013
positive regulation of cellular catabolic process GO:0031331 35 0.013
cuticle development GO:0042335 100 0.013
negative regulation of cellular protein metabolic process GO:0032269 27 0.013
post embryonic organ development GO:0048569 336 0.013
negative regulation of molecular function GO:0044092 20 0.013
regulation of programmed cell death GO:0043067 50 0.013
memory GO:0007613 3 0.013
ras protein signal transduction GO:0007265 31 0.013
regulation of synaptic transmission cholinergic GO:0032222 7 0.012
canonical wnt signaling pathway GO:0060070 3 0.012
developmental maturation GO:0021700 26 0.012
positive regulation of embryonic development GO:0040019 3 0.012
cell growth GO:0016049 44 0.012
purine nucleoside triphosphate metabolic process GO:0009144 87 0.012
ion transport GO:0006811 113 0.012
regulation of cellular localization GO:0060341 42 0.012
cellular nitrogen compound catabolic process GO:0044270 119 0.012
defecation GO:0030421 47 0.012
autophagy GO:0006914 29 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
regulation of cell projection organization GO:0031344 38 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
defense response GO:0006952 296 0.012
regulation of epithelial cell proliferation GO:0050678 1 0.012
nucleotide catabolic process GO:0009166 77 0.012
regulation of transcription dna templated GO:0006355 164 0.011
actin filament bundle assembly GO:0051017 3 0.011
regulation of anatomical structure size GO:0090066 46 0.011
negative regulation of response to external stimulus GO:0032102 3 0.011
regulation of protein modification process GO:0031399 46 0.011
regulation of neuron projection development GO:0010975 31 0.011
actin filament bundle organization GO:0061572 3 0.011
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of canonical wnt signaling pathway GO:0060828 1 0.011
positive regulation of neurogenesis GO:0050769 4 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
regulation of cell projection assembly GO:0060491 3 0.011
regulation of nucleic acid templated transcription GO:1903506 165 0.011
proteolysis GO:0006508 61 0.011
molting cycle GO:0042303 281 0.011
male mating behavior GO:0060179 26 0.011
anterior posterior axis specification GO:0009948 17 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
regulation of cellular component movement GO:0051270 62 0.010
positive regulation of cell projection organization GO:0031346 4 0.010
regulation of response to external stimulus GO:0032101 29 0.010
cell maturation GO:0048469 26 0.010
myosin filament organization GO:0031033 138 0.010

sma-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
disease of cellular proliferation DOID:14566 0 0.014