Caenorhabditis elegans

35 known processes

pfn-3 (CELE_K03E6.6)

Protein PFN-3

pfn-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism organelle organization GO:1902589 501 0.638
cellular component assembly involved in morphogenesis GO:0010927 183 0.350
anatomical structure formation involved in morphogenesis GO:0048646 250 0.338
locomotion GO:0040011 1634 0.330
muscle cell differentiation GO:0042692 171 0.306
multicellular organismal reproductive behavior GO:0033057 384 0.285
cell development GO:0048468 696 0.279
organelle organization GO:0006996 783 0.266
myofibril assembly GO:0030239 154 0.252
muscle cell development GO:0055001 158 0.242
actin cytoskeleton organization GO:0030036 184 0.239
actomyosin structure organization GO:0031032 154 0.225
post embryonic development GO:0009791 2152 0.206
macromolecular complex subunit organization GO:0043933 320 0.204
cytoskeleton organization GO:0007010 339 0.203
organelle assembly GO:0070925 214 0.200
organ development GO:0048513 1102 0.192
striated muscle cell differentiation GO:0051146 158 0.185
protein complex subunit organization GO:0071822 280 0.177
localization of cell GO:0051674 313 0.175
actin filament based process GO:0030029 191 0.173
multicellular organism reproduction GO:0032504 819 0.173
gonad development GO:0008406 840 0.167
behavior GO:0007610 527 0.165
multi multicellular organism process GO:0044706 390 0.147
cellular protein complex assembly GO:0043623 178 0.145
regulation of locomotion GO:0040012 161 0.137
striated muscle cell development GO:0055002 157 0.134
muscle structure development GO:0061061 191 0.124
oviposition GO:0018991 364 0.116
cell death GO:0008219 547 0.110
reproductive behavior GO:0019098 387 0.108
multi organism reproductive process GO:0044703 867 0.107
cell projection organization GO:0030030 231 0.102
cellular component assembly GO:0022607 293 0.101
developmental growth GO:0048589 412 0.100
embryo development ending in birth or egg hatching GO:0009792 2992 0.099
multicellular organismal reproductive process GO:0048609 815 0.097
positive regulation of multicellular organismal process GO:0051240 417 0.094
regulation of multicellular organismal process GO:0051239 726 0.093
reproductive system development GO:0061458 850 0.093
ovulation GO:0030728 33 0.090
single organism signaling GO:0044700 401 0.088
cell motility GO:0048870 313 0.088
neuron projection development GO:0031175 187 0.087
determination of adult lifespan GO:0008340 812 0.087
cellular component biogenesis GO:0044085 297 0.085
protein metabolic process GO:0019538 422 0.083
multicellular organismal aging GO:0010259 812 0.080
regulation of response to stimulus GO:0048583 243 0.080
regulation of cell motility GO:2000145 57 0.079
receptor mediated endocytosis GO:0006898 715 0.079
genitalia development GO:0048806 741 0.079
macromolecule localization GO:0033036 771 0.077
multi organism reproductive behavior GO:0044705 387 0.075
aging GO:0007568 812 0.073
regulation of cellular component movement GO:0051270 62 0.070
cellular component movement GO:0006928 388 0.068
striated muscle myosin thick filament assembly GO:0071688 138 0.068
lipid storage GO:0019915 565 0.068
regulation of biological quality GO:0065008 741 0.068
cellular macromolecular complex assembly GO:0034622 184 0.068
hermaphrodite genitalia development GO:0040035 734 0.065
development of primary sexual characteristics GO:0045137 840 0.064
single organism reproductive process GO:0044702 1196 0.064
regulation of developmental process GO:0050793 684 0.063
positive regulation of developmental growth GO:0048639 354 0.063
growth GO:0040007 562 0.060
lipid localization GO:0010876 573 0.059
endocytosis GO:0006897 819 0.058
myosin filament assembly GO:0031034 138 0.058
vesicle mediated transport GO:0016192 852 0.058
maintenance of location GO:0051235 580 0.058
microtubule based process GO:0007017 182 0.057
positive regulation of developmental process GO:0051094 408 0.057
response to abiotic stimulus GO:0009628 152 0.056
protein complex assembly GO:0006461 186 0.056
regulation of macromolecule metabolic process GO:0060255 421 0.054
cellular localization GO:0051641 360 0.053
axon development GO:0061564 163 0.053
mitotic cell cycle process GO:1903047 194 0.053
single organism localization GO:1902578 518 0.051
cellular component morphogenesis GO:0032989 318 0.051
cell cycle process GO:0022402 482 0.050
embryo development GO:0009790 3052 0.049
multi organism behavior GO:0051705 389 0.049
cell cycle GO:0007049 526 0.048
cell migration GO:0016477 306 0.048
body morphogenesis GO:0010171 620 0.047
cellular protein metabolic process GO:0044267 279 0.047
death GO:0016265 547 0.046
programmed cell death GO:0012501 500 0.045
protein complex biogenesis GO:0070271 186 0.045
transport GO:0006810 1093 0.044
protein localization GO:0008104 205 0.044
signal transduction GO:0007165 317 0.043
myosin filament organization GO:0031033 138 0.043
reproductive structure development GO:0048608 850 0.043
sex differentiation GO:0007548 909 0.042
neuron differentiation GO:0030182 217 0.040
regulation of cellular component organization GO:0051128 248 0.040
cilium morphogenesis GO:0060271 33 0.040
regulation of anatomical structure morphogenesis GO:0022603 51 0.039
intracellular signal transduction GO:0035556 96 0.039
establishment of localization GO:0051234 1171 0.039
regulation of cell communication GO:0010646 176 0.037
neurogenesis GO:0022008 236 0.037
regulation of cell migration GO:0030334 55 0.037
macromolecular complex assembly GO:0065003 193 0.036
regulation of growth GO:0040008 409 0.035
regulation of organelle organization GO:0033043 164 0.033
organonitrogen compound catabolic process GO:1901565 90 0.033
macromolecule modification GO:0043412 218 0.032
cellular protein modification process GO:0006464 207 0.031
mitotic spindle organization GO:0007052 81 0.031
negative regulation of metabolic process GO:0009892 240 0.030
cell surface receptor signaling pathway GO:0007166 149 0.030
cellular response to stress GO:0033554 162 0.029
cellular nitrogen compound catabolic process GO:0044270 119 0.029
regulation of multicellular organism growth GO:0040014 373 0.029
positive regulation of cell projection organization GO:0031346 4 0.029
regulation of signaling GO:0023051 172 0.028
single organism cellular localization GO:1902580 72 0.028
signaling GO:0023052 401 0.028
protein catabolic process GO:0030163 162 0.028
multicellular organism growth GO:0035264 385 0.028
response to wounding GO:0009611 4 0.027
regulation of cell morphogenesis GO:0022604 40 0.026
regulation of gene expression GO:0010468 366 0.026
regulation of developmental growth GO:0048638 389 0.026
phosphate containing compound metabolic process GO:0006796 232 0.026
single organism transport GO:0044765 447 0.026
cytokinesis GO:0000910 80 0.026
positive regulation of growth GO:0045927 369 0.026
negative regulation of biological process GO:0048519 567 0.025
developmental process involved in reproduction GO:0003006 1165 0.025
cell recognition GO:0008037 85 0.024
nervous system development GO:0007399 253 0.024
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.024
muscle contraction GO:0006936 43 0.024
regulation of muscle contraction GO:0006937 20 0.024
female gamete generation GO:0007292 254 0.024
cellular macromolecule localization GO:0070727 75 0.023
regulation of metabolic process GO:0019222 478 0.023
embryonic morphogenesis GO:0048598 152 0.023
cell division GO:0051301 262 0.022
regulation of phosphorus metabolic process GO:0051174 81 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.022
sensory organ morphogenesis GO:0090596 2 0.022
positive regulation of locomotion GO:0040017 42 0.022
cell proliferation GO:0008283 116 0.021
positive regulation of multicellular organism growth GO:0040018 352 0.021
inductive cell migration GO:0040039 145 0.021
cellular biosynthetic process GO:0044249 315 0.021
actin filament organization GO:0007015 21 0.021
neuron recognition GO:0008038 83 0.021
macromolecule catabolic process GO:0009057 202 0.020
mechanosensory behavior GO:0007638 25 0.020
cellular homeostasis GO:0019725 22 0.020
gene expression GO:0010467 412 0.020
regulation of phosphate metabolic process GO:0019220 81 0.020
organic substance transport GO:0071702 113 0.020
gamete generation GO:0007276 461 0.019
tissue morphogenesis GO:0048729 65 0.019
positive regulation of cell migration GO:0030335 3 0.019
protein modification process GO:0036211 207 0.018
small molecule metabolic process GO:0044281 186 0.018
cell growth GO:0016049 44 0.018
regulation of cellular protein metabolic process GO:0032268 75 0.018
apoptotic process GO:0006915 478 0.018
positive regulation of cell communication GO:0010647 69 0.018
nucleoside phosphate metabolic process GO:0006753 108 0.018
biosynthetic process GO:0009058 323 0.018
regulation of cellular metabolic process GO:0031323 305 0.017
negative regulation of signaling GO:0023057 61 0.017
establishment of localization in cell GO:0051649 318 0.017
regulation of actin filament based process GO:0032970 22 0.017
regulation of localization GO:0032879 194 0.016
positive regulation of cellular process GO:0048522 332 0.016
organic substance catabolic process GO:1901575 294 0.016
muscle tissue development GO:0060537 1 0.016
cellular response to chemical stimulus GO:0070887 129 0.016
positive regulation of macromolecule metabolic process GO:0010604 149 0.016
lamellipodium organization GO:0097581 2 0.016
nucleic acid metabolic process GO:0090304 299 0.015
neuron development GO:0048666 199 0.015
system process GO:0003008 136 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
regulation of cellular localization GO:0060341 42 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.014
regulation of signal transduction GO:0009966 135 0.014
regulation of catalytic activity GO:0050790 78 0.014
neuron projection morphogenesis GO:0048812 114 0.014
cellular catabolic process GO:0044248 199 0.014
protein homooligomerization GO:0051260 3 0.014
axonal fasciculation GO:0007413 79 0.014
inactivation of mapkkk activity GO:0051390 2 0.014
negative regulation of macromolecule metabolic process GO:0010605 229 0.014
negative regulation of signal transduction GO:0009968 60 0.013
catabolic process GO:0009056 318 0.013
organonitrogen compound metabolic process GO:1901564 151 0.013
tissue development GO:0009888 112 0.013
directional locomotion GO:0033058 14 0.013
negative regulation of cellular process GO:0048523 239 0.013
regulation of cell death GO:0010941 65 0.013
generation of neurons GO:0048699 235 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
mitotic nuclear division GO:0007067 89 0.012
epithelial cell proliferation GO:0050673 1 0.012
cellular protein localization GO:0034613 75 0.012
epithelial tube morphogenesis GO:0060562 1 0.012
spindle organization GO:0007051 92 0.012
regulation of molecular function GO:0065009 89 0.012
positive regulation of neuron differentiation GO:0045666 4 0.012
negative regulation of ion transmembrane transport GO:0034766 3 0.012
negative regulation of developmental process GO:0051093 227 0.012
chromosome organization GO:0051276 104 0.012
response to chemical GO:0042221 356 0.012
organic substance biosynthetic process GO:1901576 323 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.011
secretion GO:0046903 147 0.011
phosphorylation GO:0016310 116 0.011
organelle fission GO:0048285 363 0.011
negative regulation of molecular function GO:0044092 20 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
posttranscriptional gene silencing GO:0016441 143 0.010
sexual reproduction GO:0019953 546 0.010
lamellipodium assembly GO:0030032 2 0.010
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
positive regulation of cellular component organization GO:0051130 34 0.010
negative regulation of cell communication GO:0010648 61 0.010
regulation of cell differentiation GO:0045595 81 0.010
positive regulation of molecular function GO:0044093 61 0.010
regulation of cell cell adhesion GO:0022407 1 0.010
apoptotic cell clearance GO:0043277 111 0.010
cellular amino acid metabolic process GO:0006520 15 0.010

pfn-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
myopathy DOID:423 0 0.022
muscular disease DOID:0080000 0 0.022
heart disease DOID:114 0 0.022
cardiomyopathy DOID:0050700 0 0.022
cardiovascular system disease DOID:1287 0 0.022
musculoskeletal system disease DOID:17 0 0.022
muscle tissue disease DOID:66 0 0.022
nervous system disease DOID:863 0 0.018