Caenorhabditis elegans

20 known processes

vars-1 (CELE_ZC513.4)

Protein VARS-1

vars-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.852
single organism reproductive process GO:0044702 1196 0.580
embryo development ending in birth or egg hatching GO:0009792 2992 0.574
embryo development GO:0009790 3052 0.525
developmental process involved in reproduction GO:0003006 1165 0.449
sexual reproduction GO:0019953 546 0.447
vesicle mediated transport GO:0016192 852 0.408
multicellular organismal reproductive process GO:0048609 815 0.360
multicellular organism reproduction GO:0032504 819 0.335
aging GO:0007568 812 0.333
locomotion GO:0040011 1634 0.297
multicellular organismal aging GO:0010259 812 0.254
regulation of multicellular organismal process GO:0051239 726 0.244
Worm
hermaphrodite genitalia development GO:0040035 734 0.240
development of primary sexual characteristics GO:0045137 840 0.233
reproductive structure development GO:0048608 850 0.228
gamete generation GO:0007276 461 0.219
reproductive system development GO:0061458 850 0.215
organelle fission GO:0048285 363 0.201
receptor mediated endocytosis GO:0006898 715 0.196
transport GO:0006810 1093 0.187
regulation of macromolecule metabolic process GO:0060255 421 0.179
determination of adult lifespan GO:0008340 812 0.168
endocytosis GO:0006897 819 0.162
sex differentiation GO:0007548 909 0.150
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.149
multi organism reproductive process GO:0044703 867 0.147
cell death GO:0008219 547 0.134
Worm
female gamete generation GO:0007292 254 0.133
pronuclear migration GO:0035046 51 0.127
regulation of developmental process GO:0050793 684 0.122
Worm
protein complex subunit organization GO:0071822 280 0.120
meiotic chromosome segregation GO:0045132 139 0.118
meiotic nuclear division GO:0007126 300 0.114
establishment of localization GO:0051234 1171 0.107
genitalia development GO:0048806 741 0.103
nucleus localization GO:0051647 55 0.101
cellular component assembly GO:0022607 293 0.097
organ development GO:0048513 1102 0.097
regulation of metabolic process GO:0019222 478 0.094
cellular protein metabolic process GO:0044267 279 0.091
meiotic cell cycle GO:0051321 335 0.090
multicellular organismal reproductive behavior GO:0033057 384 0.088
body morphogenesis GO:0010171 620 0.078
germ cell development GO:0007281 351 0.078
macromolecule biosynthetic process GO:0009059 250 0.075
growth GO:0040007 562 0.073
Worm
cell development GO:0048468 696 0.073
multi organism behavior GO:0051705 389 0.073
gonad development GO:0008406 840 0.072
negative regulation of macromolecule metabolic process GO:0010605 229 0.072
meiotic cell cycle process GO:1903046 170 0.071
oviposition GO:0018991 364 0.071
organelle organization GO:0006996 783 0.066
fertilization GO:0009566 63 0.065
negative regulation of gene expression GO:0010629 217 0.065
single fertilization GO:0007338 61 0.063
regulation of biological quality GO:0065008 741 0.061
positive regulation of multicellular organism growth GO:0040018 352 0.060
Worm
cell division GO:0051301 262 0.059
macromolecule localization GO:0033036 771 0.059
immune response GO:0006955 192 0.057
cell cycle GO:0007049 526 0.055
maintenance of location GO:0051235 580 0.052
behavior GO:0007610 527 0.052
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.052
Worm
negative regulation of biological process GO:0048519 567 0.051
cellular component biogenesis GO:0044085 297 0.051
organonitrogen compound metabolic process GO:1901564 151 0.050
positive regulation of developmental process GO:0051094 408 0.048
Worm
regulation of developmental growth GO:0048638 389 0.048
Worm
catabolic process GO:0009056 318 0.047
regulation of cellular biosynthetic process GO:0031326 189 0.047
oogenesis GO:0048477 229 0.047
negative regulation of metabolic process GO:0009892 240 0.047
response to external stimulus GO:0009605 289 0.047
protein metabolic process GO:0019538 422 0.046
organelle assembly GO:0070925 214 0.046
lipid storage GO:0019915 565 0.046
developmental growth GO:0048589 412 0.046
Worm
positive regulation of developmental growth GO:0048639 354 0.045
Worm
multi organism reproductive behavior GO:0044705 387 0.045
signaling GO:0023052 401 0.045
multi multicellular organism process GO:0044706 390 0.044
cell morphogenesis GO:0000902 163 0.043
posttranscriptional regulation of gene expression GO:0010608 166 0.043
lipid localization GO:0010876 573 0.043
programmed cell death GO:0012501 500 0.042
Worm
reproductive behavior GO:0019098 387 0.042
regulation of nitrogen compound metabolic process GO:0051171 222 0.042
phosphate containing compound metabolic process GO:0006796 232 0.042
protein complex assembly GO:0006461 186 0.042
organic substance catabolic process GO:1901575 294 0.041
cell projection organization GO:0030030 231 0.040
cell cycle process GO:0022402 482 0.040
macromolecular complex subunit organization GO:0043933 320 0.039
organic cyclic compound biosynthetic process GO:1901362 195 0.039
regulation of gene expression epigenetic GO:0040029 163 0.039
positive regulation of multicellular organismal process GO:0051240 417 0.039
Worm
cellular macromolecule biosynthetic process GO:0034645 247 0.038
single organism organelle organization GO:1902589 501 0.038
cellular localization GO:0051641 360 0.038
neurogenesis GO:0022008 236 0.037
cellular component morphogenesis GO:0032989 318 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
Worm
purine ribonucleotide catabolic process GO:0009154 75 0.036
positive regulation of growth GO:0045927 369 0.036
Worm
response to chemical GO:0042221 356 0.035
single organism signaling GO:0044700 401 0.035
organic substance biosynthetic process GO:1901576 323 0.035
regulation of macromolecule biosynthetic process GO:0010556 189 0.035
carboxylic acid metabolic process GO:0019752 34 0.035
establishment of localization in cell GO:0051649 318 0.034
cellular biosynthetic process GO:0044249 315 0.034
positive regulation of metabolic process GO:0009893 187 0.034
nucleic acid metabolic process GO:0090304 299 0.034
cellular response to stress GO:0033554 162 0.034
phosphorus metabolic process GO:0006793 232 0.033
ion transport GO:0006811 113 0.033
axon development GO:0061564 163 0.033
heterocycle catabolic process GO:0046700 119 0.033
neuron development GO:0048666 199 0.032
small molecule biosynthetic process GO:0044283 38 0.032
regulation of gene expression GO:0010468 366 0.032
regulation of primary metabolic process GO:0080090 292 0.032
cellular macromolecular complex assembly GO:0034622 184 0.032
oxoacid metabolic process GO:0043436 47 0.031
cytokinesis GO:0000910 80 0.031
nucleoside monophosphate metabolic process GO:0009123 46 0.031
negative regulation of cellular process GO:0048523 239 0.031
head development GO:0060322 1 0.031
negative regulation of biosynthetic process GO:0009890 65 0.030
cellular amino acid metabolic process GO:0006520 15 0.030
biosynthetic process GO:0009058 323 0.030
regulation of cellular metabolic process GO:0031323 305 0.030
intracellular receptor signaling pathway GO:0030522 2 0.030
small molecule metabolic process GO:0044281 186 0.030
regulation of growth GO:0040008 409 0.029
Worm
cell motility GO:0048870 313 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
cytoskeleton organization GO:0007010 339 0.028
neuron differentiation GO:0030182 217 0.028
macromolecular complex assembly GO:0065003 193 0.028
gene silencing GO:0016458 143 0.028
regulation of behavior GO:0050795 97 0.027
cellular catabolic process GO:0044248 199 0.027
ribose phosphate metabolic process GO:0019693 99 0.027
purine nucleoside catabolic process GO:0006152 75 0.027
aromatic compound catabolic process GO:0019439 116 0.027
organonitrogen compound catabolic process GO:1901565 90 0.026
purine nucleoside metabolic process GO:0042278 92 0.026
macromolecule catabolic process GO:0009057 202 0.026
secretion by cell GO:0032940 138 0.026
purine nucleoside monophosphate catabolic process GO:0009128 28 0.026
innate immune response GO:0045087 190 0.025
inductive cell migration GO:0040039 145 0.025
heterocycle biosynthetic process GO:0018130 187 0.025
ribonucleoprotein complex assembly GO:0022618 4 0.025
cellular nitrogen compound catabolic process GO:0044270 119 0.024
establishment of nucleus localization GO:0040023 55 0.024
multicellular organism growth GO:0035264 385 0.024
Worm
negative regulation of cellular biosynthetic process GO:0031327 65 0.024
localization of cell GO:0051674 313 0.024
death GO:0016265 547 0.024
Worm
phosphorylation GO:0016310 116 0.023
nucleoside triphosphate catabolic process GO:0009143 72 0.023
negative regulation of cellular metabolic process GO:0031324 95 0.023
nucleobase containing compound biosynthetic process GO:0034654 184 0.023
regulation of cellular component organization GO:0051128 248 0.023
translation GO:0006412 37 0.023
apoptotic process GO:0006915 478 0.023
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.023
cellular component movement GO:0006928 388 0.023
single organism localization GO:1902578 518 0.022
single organism transport GO:0044765 447 0.022
cell type specific apoptotic process GO:0097285 4 0.022
positive regulation of locomotion GO:0040017 42 0.022
molting cycle GO:0042303 281 0.022
Worm
digestive tract development GO:0048565 122 0.022
purine ribonucleotide metabolic process GO:0009150 95 0.022
regulation of nucleic acid templated transcription GO:1903506 165 0.021
cell migration GO:0016477 306 0.021
gene silencing by rna GO:0031047 143 0.021
cell cell signaling GO:0007267 118 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
cellular response to inorganic substance GO:0071241 3 0.020
gene expression GO:0010467 412 0.020
defense response GO:0006952 296 0.020
organic cyclic compound catabolic process GO:1901361 119 0.020
regulation of biosynthetic process GO:0009889 189 0.020
response to wounding GO:0009611 4 0.019
nuclear migration GO:0007097 54 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.019
cellular amine metabolic process GO:0044106 15 0.019
regulation of organelle organization GO:0033043 164 0.018
nucleobase containing compound metabolic process GO:0006139 406 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cation transport GO:0006812 78 0.018
digestive system development GO:0055123 122 0.018
generation of neurons GO:0048699 235 0.018
positive regulation of neurotransmitter transport GO:0051590 11 0.018
regulation of neurotransmitter secretion GO:0046928 16 0.018
nucleobase containing compound catabolic process GO:0034655 114 0.017
synaptic transmission GO:0007268 106 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.017
cellular ketone metabolic process GO:0042180 14 0.017
regulation of response to stimulus GO:0048583 243 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
regulation of lipid biosynthetic process GO:0046890 1 0.017
cellular nitrogen compound biosynthetic process GO:0044271 192 0.017
protein complex biogenesis GO:0070271 186 0.017
oocyte construction GO:0007308 2 0.017
regulation of catabolic process GO:0009894 57 0.017
nucleoside metabolic process GO:0009116 99 0.017
regulation of lipid metabolic process GO:0019216 4 0.016
glycosyl compound catabolic process GO:1901658 79 0.016
purine containing compound metabolic process GO:0072521 95 0.016
amine metabolic process GO:0009308 15 0.016
muscle structure development GO:0061061 191 0.016
nucleic acid templated transcription GO:0097659 169 0.016
actin filament based process GO:0030029 191 0.016
nucleotide catabolic process GO:0009166 77 0.016
feeding behavior GO:0007631 70 0.016
vulval development GO:0040025 333 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
membrane invagination GO:0010324 98 0.015
dna metabolic process GO:0006259 74 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
translational initiation GO:0006413 2 0.015
rna interference GO:0016246 137 0.015
regulation of rna metabolic process GO:0051252 173 0.015
nucleoside phosphate catabolic process GO:1901292 77 0.015
positive regulation of cellular metabolic process GO:0031325 178 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.014
regulation of protein metabolic process GO:0051246 81 0.014
single organism catabolic process GO:0044712 129 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
development of primary male sexual characteristics GO:0046546 4 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.014
negative regulation of rna metabolic process GO:0051253 53 0.014
nucleoside monophosphate catabolic process GO:0009125 28 0.014
cellular protein complex assembly GO:0043623 178 0.014
purine nucleoside monophosphate metabolic process GO:0009126 43 0.014
transcription from rna polymerase ii promoter GO:0006366 149 0.014
secretion GO:0046903 147 0.014
nervous system development GO:0007399 253 0.014
organophosphate metabolic process GO:0019637 125 0.014
organophosphate catabolic process GO:0046434 81 0.014
response to external biotic stimulus GO:0043207 101 0.014
cellular component assembly involved in morphogenesis GO:0010927 183 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
ribonucleoside monophosphate metabolic process GO:0009161 45 0.013
organic acid metabolic process GO:0006082 47 0.013
nucleotide metabolic process GO:0009117 108 0.013
cell recognition GO:0008037 85 0.013
positive regulation of biosynthetic process GO:0009891 109 0.013
tube morphogenesis GO:0035239 79 0.013
regulation of multi organism process GO:0043900 69 0.013
protein oligomerization GO:0051259 4 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
negative regulation of transcription dna templated GO:0045892 53 0.013
regulation of cellular catabolic process GO:0031329 51 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.012
purine ribonucleoside metabolic process GO:0046128 92 0.012
regulation of rna biosynthetic process GO:2001141 165 0.012
positive regulation of protein metabolic process GO:0051247 45 0.012
purine nucleoside triphosphate metabolic process GO:0009144 87 0.012
phagocytosis engulfment GO:0006911 98 0.012
rna localization GO:0006403 3 0.012
response to organic substance GO:0010033 131 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
inorganic ion transmembrane transport GO:0098660 54 0.012
striated muscle cell development GO:0055002 157 0.012
positive regulation of macromolecule metabolic process GO:0010604 149 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
regulation of cell cycle GO:0051726 194 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
cellular protein modification process GO:0006464 207 0.012
protein catabolic process GO:0030163 162 0.011
organelle localization GO:0051640 127 0.011
protein localization GO:0008104 205 0.011
regulation of anatomical structure morphogenesis GO:0022603 51 0.011
negative regulation of multicellular organismal process GO:0051241 236 0.011
nucleoside triphosphate metabolic process GO:0009141 87 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.011
apoptotic cell clearance GO:0043277 111 0.011
myosin filament organization GO:0031033 138 0.011
carbohydrate derivative catabolic process GO:1901136 82 0.011
neuron projection development GO:0031175 187 0.011
myosin filament assembly GO:0031034 138 0.011
ribonucleotide metabolic process GO:0009259 99 0.011
regulation of localization GO:0032879 194 0.011
positive regulation of cellular process GO:0048522 332 0.011
regulation of phosphorus metabolic process GO:0051174 81 0.011
response to biotic stimulus GO:0009607 101 0.011
regulation of multicellular organismal development GO:2000026 317 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.010
peptidyl amino acid modification GO:0018193 58 0.010
cell proliferation GO:0008283 116 0.010
response to other organism GO:0051707 101 0.010
chromosome segregation GO:0007059 180 0.010
axonal fasciculation GO:0007413 79 0.010
negative regulation of nematode larval development GO:0061064 208 0.010
organ morphogenesis GO:0009887 67 0.010
myofibril assembly GO:0030239 154 0.010
actomyosin structure organization GO:0031032 154 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.010
protein modification process GO:0036211 207 0.010
neuromuscular junction development GO:0007528 2 0.010
engulfment of apoptotic cell GO:0043652 94 0.010

vars-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of metabolism DOID:0014667 0 0.011