Caenorhabditis elegans

68 known processes

aspm-1 (CELE_C45G3.1)

Protein ASPM-1

aspm-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.966
mitotic cell cycle process GO:1903047 194 0.948
Fly
embryo development GO:0009790 3052 0.873
cytoskeleton organization GO:0007010 339 0.812
mitotic nuclear division GO:0007067 89 0.793
meiotic nuclear division GO:0007126 300 0.746
organelle fission GO:0048285 363 0.725
organelle organization GO:0006996 783 0.707
cell cycle process GO:0022402 482 0.658
chromosome segregation GO:0007059 180 0.590
meiotic cell cycle process GO:1903046 170 0.567
microtubule based process GO:0007017 182 0.534
meiotic cell cycle GO:0051321 335 0.513
cell projection organization GO:0030030 231 0.506
spindle organization GO:0007051 92 0.499
organelle assembly GO:0070925 214 0.494
Mouse
locomotion GO:0040011 1634 0.493
gonad development GO:0008406 840 0.483
mitotic spindle organization GO:0007052 81 0.468
Fly
apoptotic process GO:0006915 478 0.466
attachment of mitotic spindle microtubules to kinetochore GO:0051315 6 0.425
establishment of localization GO:0051234 1171 0.406
cell cycle GO:0007049 526 0.398
development of primary sexual characteristics GO:0045137 840 0.355
transport GO:0006810 1093 0.354
centromere complex assembly GO:0034508 5 0.352
protein complex subunit organization GO:0071822 280 0.347
gene expression GO:0010467 412 0.346
dna conformation change GO:0071103 11 0.329
post embryonic development GO:0009791 2152 0.321
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.313
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.301
negative regulation of gene expression epigenetic GO:0045814 2 0.296
kinetochore assembly GO:0051382 5 0.294
hermaphrodite genitalia development GO:0040035 734 0.278
multicellular organism reproduction GO:0032504 819 0.278
Mouse Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.275
regulation of macromolecule metabolic process GO:0060255 421 0.272
nucleic acid metabolic process GO:0090304 299 0.272
nucleobase containing compound metabolic process GO:0006139 406 0.264
tissue morphogenesis GO:0048729 65 0.263
single organism localization GO:1902578 518 0.252
developmental process involved in reproduction GO:0003006 1165 0.246
cellular localization GO:0051641 360 0.246
carbohydrate derivative metabolic process GO:1901135 141 0.237
chromosome organization GO:0051276 104 0.237
Fly
sister chromatid segregation GO:0000819 46 0.236
cellular component morphogenesis GO:0032989 318 0.230
regulation of gene expression epigenetic GO:0040029 163 0.226
macromolecular complex subunit organization GO:0043933 320 0.224
polar body extrusion after meiotic divisions GO:0040038 14 0.216
regulation of nitrogen compound metabolic process GO:0051171 222 0.210
purine nucleoside metabolic process GO:0042278 92 0.209
cellular component biogenesis GO:0044085 297 0.205
Mouse Fly
organonitrogen compound catabolic process GO:1901565 90 0.204
sexual reproduction GO:0019953 546 0.202
Mouse Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.193
ribonucleoside metabolic process GO:0009119 98 0.193
glycosyl compound metabolic process GO:1901657 100 0.192
organ morphogenesis GO:0009887 67 0.182
Fly
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.182
chromosome localization GO:0050000 10 0.179
purine nucleoside catabolic process GO:0006152 75 0.175
vesicle mediated transport GO:0016192 852 0.169
nucleotide metabolic process GO:0009117 108 0.168
programmed cell death GO:0012501 500 0.167
single organism reproductive process GO:0044702 1196 0.165
receptor mediated endocytosis GO:0006898 715 0.165
meiotic chromosome segregation GO:0045132 139 0.165
cellular component assembly GO:0022607 293 0.164
Mouse Fly
single organism organelle organization GO:1902589 501 0.162
regulation of cell cycle GO:0051726 194 0.162
ribose phosphate metabolic process GO:0019693 99 0.161
cell death GO:0008219 547 0.161
localization of cell GO:0051674 313 0.159
Mouse
cellular component assembly involved in morphogenesis GO:0010927 183 0.157
establishment of localization in cell GO:0051649 318 0.156
organophosphate catabolic process GO:0046434 81 0.153
regulation of primary metabolic process GO:0080090 292 0.152
single fertilization GO:0007338 61 0.152
biosynthetic process GO:0009058 323 0.151
fertilization GO:0009566 63 0.150
cell motility GO:0048870 313 0.149
Mouse
cell division GO:0051301 262 0.147
Mouse Fly
heterocycle biosynthetic process GO:0018130 187 0.145
protein complex assembly GO:0006461 186 0.144
Mouse Fly
organophosphate metabolic process GO:0019637 125 0.143
purine ribonucleoside catabolic process GO:0046130 75 0.141
endocytosis GO:0006897 819 0.140
carbohydrate derivative catabolic process GO:1901136 82 0.140
catabolic process GO:0009056 318 0.139
nucleoside phosphate catabolic process GO:1901292 77 0.138
regulation of biological quality GO:0065008 741 0.135
Mouse
small molecule metabolic process GO:0044281 186 0.135
organonitrogen compound metabolic process GO:1901564 151 0.134
cell migration GO:0016477 306 0.131
Mouse
dna packaging GO:0006323 7 0.131
organic substance biosynthetic process GO:1901576 323 0.129
regulation of gene expression GO:0010468 366 0.128
metaphase plate congression GO:0051310 5 0.128
multi organism reproductive process GO:0044703 867 0.125
Mouse Fly
purine ribonucleotide metabolic process GO:0009150 95 0.122
nucleobase containing small molecule metabolic process GO:0055086 115 0.121
ribonucleoside catabolic process GO:0042454 77 0.121
protein complex biogenesis GO:0070271 186 0.120
Mouse Fly
regulation of cellular component organization GO:0051128 248 0.119
nucleoside phosphate metabolic process GO:0006753 108 0.118
nucleobase containing compound catabolic process GO:0034655 114 0.117
gene silencing GO:0016458 143 0.116
atp metabolic process GO:0046034 42 0.115
sex differentiation GO:0007548 909 0.115
purine nucleotide catabolic process GO:0006195 75 0.114
attachment of spindle microtubules to kinetochore GO:0008608 8 0.114
homeostatic process GO:0042592 51 0.112
oviposition GO:0018991 364 0.109
nucleoside triphosphate catabolic process GO:0009143 72 0.106
purine nucleoside triphosphate catabolic process GO:0009146 72 0.104
genitalia development GO:0048806 741 0.103
macromolecular complex assembly GO:0065003 193 0.102
Mouse Fly
ribonucleotide metabolic process GO:0009259 99 0.102
anatomical structure formation involved in morphogenesis GO:0048646 250 0.101
Fly
mitotic metaphase plate congression GO:0007080 5 0.100
nuclear migration GO:0007097 54 0.099
Fly
nucleoside monophosphate metabolic process GO:0009123 46 0.099
nucleoside triphosphate metabolic process GO:0009141 87 0.098
regulation of metabolic process GO:0019222 478 0.097
cellular macromolecule biosynthetic process GO:0034645 247 0.095
cell development GO:0048468 696 0.094
Mouse Fly
dna duplex unwinding GO:0032508 3 0.094
negative regulation of biological process GO:0048519 567 0.094
Mouse
spindle assembly involved in mitosis GO:0090307 6 0.093
cellular biosynthetic process GO:0044249 315 0.091
ribonucleoside triphosphate metabolic process GO:0009199 87 0.091
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.091
negative regulation of metabolic process GO:0009892 240 0.090
establishment of spindle localization GO:0051293 51 0.090
establishment of chromosome localization GO:0051303 10 0.089
organelle localization GO:0051640 127 0.088
multicellular organismal reproductive process GO:0048609 815 0.087
Mouse Fly
ribonucleotide catabolic process GO:0009261 75 0.087
purine containing compound catabolic process GO:0072523 75 0.086
single organism transport GO:0044765 447 0.085
glycosyl compound catabolic process GO:1901658 79 0.085
regulation of cellular metabolic process GO:0031323 305 0.084
actomyosin structure organization GO:0031032 154 0.083
head development GO:0060322 1 0.082
Mouse Fly
chromatin assembly or disassembly GO:0006333 1 0.082
macromolecule localization GO:0033036 771 0.082
actin filament based process GO:0030029 191 0.082
Fly
microtubule polymerization or depolymerization GO:0031109 22 0.082
Fly
nucleoside metabolic process GO:0009116 99 0.078
cellular protein metabolic process GO:0044267 279 0.076
ribonucleoside triphosphate catabolic process GO:0009203 72 0.076
phosphorus metabolic process GO:0006793 232 0.075
aromatic compound biosynthetic process GO:0019438 192 0.075
regulation of mitotic cell cycle GO:0007346 76 0.074
organic cyclic compound biosynthetic process GO:1901362 195 0.074
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.074
neuron differentiation GO:0030182 217 0.072
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 87 0.069
purine ribonucleoside monophosphate catabolic process GO:0009169 28 0.068
neuron projection development GO:0031175 187 0.068
purine containing compound metabolic process GO:0072521 95 0.067
positive regulation of metabolic process GO:0009893 187 0.065
negative regulation of cellular process GO:0048523 239 0.065
Mouse
maintenance of location in cell GO:0051651 12 0.065
Mouse
cellular nitrogen compound catabolic process GO:0044270 119 0.064
myosin filament assembly GO:0031034 138 0.064
regulation of multicellular organismal process GO:0051239 726 0.064
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 45 0.062
regulation of microtubule cytoskeleton organization GO:0070507 21 0.062
striated muscle cell development GO:0055002 157 0.062
regulation of rna biosynthetic process GO:2001141 165 0.061
nucleoside catabolic process GO:0009164 78 0.061
negative regulation of gene expression GO:0010629 217 0.061
mitotic sister chromatid segregation GO:0000070 38 0.061
purine nucleoside monophosphate metabolic process GO:0009126 43 0.060
nucleus organization GO:0006997 38 0.060
cell morphogenesis GO:0000902 163 0.057
reproductive system development GO:0061458 850 0.056
cellular protein modification process GO:0006464 207 0.056
regulation of cellular biosynthetic process GO:0031326 189 0.056
dna metabolic process GO:0006259 74 0.056
multicellular organismal aging GO:0010259 812 0.055
aromatic compound catabolic process GO:0019439 116 0.055
determination of adult lifespan GO:0008340 812 0.054
maintenance of location GO:0051235 580 0.053
Mouse
chromosome condensation GO:0030261 6 0.053
cell part morphogenesis GO:0032990 152 0.053
aging GO:0007568 812 0.053
neuron development GO:0048666 199 0.052
death GO:0016265 547 0.052
purine nucleotide metabolic process GO:0006163 95 0.052
regulation of mitotic spindle organization GO:0060236 3 0.050
multicellular organismal reproductive behavior GO:0033057 384 0.050
neurogenesis GO:0022008 236 0.049
Mouse
cellular catabolic process GO:0044248 199 0.049
muscle structure development GO:0061061 191 0.049
rrna metabolic process GO:0016072 3 0.049
muscle cell development GO:0055001 158 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.047
protein metabolic process GO:0019538 422 0.047
atp catabolic process GO:0006200 27 0.047
lipid storage GO:0019915 565 0.047
pronuclear migration GO:0035046 51 0.046
cellular macromolecular complex assembly GO:0034622 184 0.046
Fly
myofibril assembly GO:0030239 154 0.046
cell projection morphogenesis GO:0048858 148 0.046
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.045
cellular component movement GO:0006928 388 0.045
Mouse
regulation of localization GO:0032879 194 0.045
maintenance of protein location GO:0045185 15 0.045
organ development GO:0048513 1102 0.045
reproductive behavior GO:0019098 387 0.045
muscle cell differentiation GO:0042692 171 0.044
protein localization GO:0008104 205 0.043
multi organism reproductive behavior GO:0044705 387 0.043
lipid localization GO:0010876 573 0.043
striated muscle myosin thick filament assembly GO:0071688 138 0.043
gene silencing by rna GO:0031047 143 0.042
reproductive structure development GO:0048608 850 0.042
posttranscriptional gene silencing GO:0016441 143 0.041
molting cycle GO:0042303 281 0.041
cellular protein complex assembly GO:0043623 178 0.041
Fly
myosin filament organization GO:0031033 138 0.040
signal transduction GO:0007165 317 0.040
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.039
multi multicellular organism process GO:0044706 390 0.038
axon development GO:0061564 163 0.038
body morphogenesis GO:0010171 620 0.038
meiotic cytokinesis GO:0033206 15 0.038
rna biosynthetic process GO:0032774 169 0.038
kinetochore organization GO:0051383 7 0.038
Fly
organic cyclic compound catabolic process GO:1901361 119 0.037
microtubule anchoring GO:0034453 8 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.036
nucleotide catabolic process GO:0009166 77 0.035
nervous system development GO:0007399 253 0.034
Mouse Fly
posttranscriptional gene silencing by rna GO:0035194 143 0.034
establishment of nucleus localization GO:0040023 55 0.034
Fly
multi organism behavior GO:0051705 389 0.033
ribonucleoside monophosphate catabolic process GO:0009158 28 0.033
regulation of nucleic acid templated transcription GO:1903506 165 0.032
chromatin remodeling GO:0006338 2 0.032
gamete generation GO:0007276 461 0.032
Mouse Fly
behavior GO:0007610 527 0.032
single organism biosynthetic process GO:0044711 91 0.031
regulation of organelle organization GO:0033043 164 0.030
peptidyl amino acid modification GO:0018193 58 0.030
cellular response to stress GO:0033554 162 0.030
nucleus localization GO:0051647 55 0.030
Fly
rna interference GO:0016246 137 0.030
generation of neurons GO:0048699 235 0.029
Mouse
regulation of cell cycle process GO:0010564 145 0.029
signaling GO:0023052 401 0.029
Mouse
maintenance of protein location in cell GO:0032507 12 0.029
mitotic g2 m transition checkpoint GO:0044818 1 0.029
macromolecule modification GO:0043412 218 0.028
spermatogenesis GO:0007283 41 0.028
Mouse
tube development GO:0035295 126 0.028
dna geometric change GO:0032392 3 0.028
regulation of response to stimulus GO:0048583 243 0.028
Mouse
spindle localization GO:0051653 51 0.028
purine ribonucleotide catabolic process GO:0009154 75 0.028
organic substance transport GO:0071702 113 0.028
response to external stimulus GO:0009605 289 0.028
cytokinesis GO:0000910 80 0.027
protein modification process GO:0036211 207 0.027
regulation of meiotic cell cycle GO:0051445 136 0.027
positive regulation of cellular process GO:0048522 332 0.027
Mouse
olfactory behavior GO:0042048 27 0.026
positive regulation of developmental process GO:0051094 408 0.026
Mouse
mitotic chromosome condensation GO:0007076 3 0.026
cytoskeleton dependent cytokinesis GO:0061640 35 0.025
regulation of nucleocytoplasmic transport GO:0046822 3 0.025
rrna processing GO:0006364 3 0.025
germ cell development GO:0007281 351 0.024
Mouse Fly
single organism catabolic process GO:0044712 129 0.024
actin cytoskeleton organization GO:0030036 184 0.024
Fly
developmental growth GO:0048589 412 0.023
Mouse
heterocycle catabolic process GO:0046700 119 0.023
macromolecule biosynthetic process GO:0009059 250 0.023
cellular protein localization GO:0034613 75 0.022
cellular macromolecule localization GO:0070727 75 0.022
establishment of organelle localization GO:0051656 123 0.022
cellular response to dna damage stimulus GO:0006974 41 0.022
histone modification GO:0016570 30 0.022
regulation of multicellular organism growth GO:0040014 373 0.022
purine nucleoside monophosphate catabolic process GO:0009128 28 0.022
nucleobase containing compound biosynthetic process GO:0034654 184 0.022
chemotaxis GO:0006935 120 0.021
positive regulation of cellular biosynthetic process GO:0031328 109 0.021
rna metabolic process GO:0016070 228 0.021
multicellular organism growth GO:0035264 385 0.021
cuticle development GO:0042335 100 0.021
regulation of meiosis GO:0040020 94 0.021
purine ribonucleoside metabolic process GO:0046128 92 0.021
male gamete generation GO:0048232 41 0.021
Mouse
negative regulation of macromolecule metabolic process GO:0010605 229 0.021
regulation of cell death GO:0010941 65 0.020
positive regulation of developmental growth GO:0048639 354 0.020
collagen and cuticulin based cuticle development GO:0040002 99 0.020
neuron projection morphogenesis GO:0048812 114 0.020
regulation of microtubule based process GO:0032886 21 0.020
centrosomal and pronuclear rotation GO:0035047 6 0.020
intracellular transport GO:0046907 77 0.020
embryonic morphogenesis GO:0048598 152 0.019
tube morphogenesis GO:0035239 79 0.019
negative regulation of rna metabolic process GO:0051253 53 0.019
regulation of programmed cell death GO:0043067 50 0.019
sensory organ morphogenesis GO:0090596 2 0.018
dna topological change GO:0006265 1 0.018
single organism intracellular transport GO:1902582 70 0.018
mitotic spindle stabilization GO:0043148 2 0.018
organic substance catabolic process GO:1901575 294 0.018
female meiotic division GO:0007143 17 0.018
cell morphogenesis involved in differentiation GO:0000904 112 0.017
digestive system development GO:0055123 122 0.017
tissue development GO:0009888 112 0.017
establishment or maintenance of cell polarity GO:0007163 63 0.017
regulation of helicase activity GO:0051095 2 0.017
oxoacid metabolic process GO:0043436 47 0.017
detection of external stimulus GO:0009581 4 0.017
positive regulation of cellular metabolic process GO:0031325 178 0.017
female gamete generation GO:0007292 254 0.016
Mouse Fly
regulation of cytoplasmic transport GO:1903649 3 0.016
covalent chromatin modification GO:0016569 30 0.016
rna processing GO:0006396 34 0.016
negative regulation of cellular metabolic process GO:0031324 95 0.016
organic acid metabolic process GO:0006082 47 0.016
phosphorylation GO:0016310 116 0.016
internal peptidyl lysine acetylation GO:0018393 3 0.016
nucleoside monophosphate catabolic process GO:0009125 28 0.016
sister chromatid biorientation GO:0031134 2 0.015
response to inorganic substance GO:0010035 50 0.015
response to wounding GO:0009611 4 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.015
Mouse Fly
regulation of nuclear division GO:0051783 115 0.014
ribonucleoprotein complex assembly GO:0022618 4 0.014
regulation of cell division GO:0051302 142 0.014
Mouse
cellular amine metabolic process GO:0044106 15 0.014
regulation of protein import into nucleus GO:0042306 3 0.014
regulation of biosynthetic process GO:0009889 189 0.014
amine metabolic process GO:0009308 15 0.014
epithelium development GO:0060429 68 0.014
positive regulation of multicellular organismal process GO:0051240 417 0.014
Mouse
axonogenesis GO:0007409 102 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
cell type specific apoptotic process GO:0097285 4 0.013
cell proliferation GO:0008283 116 0.013
Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.013
regulation of developmental growth GO:0048638 389 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
striated muscle cell differentiation GO:0051146 158 0.013
protein oligomerization GO:0051259 4 0.013
spindle assembly GO:0051225 8 0.012
Mouse
proteolysis GO:0006508 61 0.012
protein transport GO:0015031 45 0.012
peptidyl lysine acetylation GO:0018394 3 0.012
membrane organization GO:0061024 135 0.012
mrna metabolic process GO:0016071 31 0.012
macromolecule catabolic process GO:0009057 202 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
protein dna complex subunit organization GO:0071824 7 0.012
regulation of transcription dna templated GO:0006355 164 0.012
regulation of multi organism process GO:0043900 69 0.012
regeneration GO:0031099 4 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
microtubule based movement GO:0007018 33 0.012
cellular response to abiotic stimulus GO:0071214 4 0.012
chemosensory behavior GO:0007635 33 0.012
response to external biotic stimulus GO:0043207 101 0.012
regulation of phosphate metabolic process GO:0019220 81 0.012
dna replication GO:0006260 15 0.012
chromatin assembly GO:0031497 1 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
chromosome organization involved in meiosis GO:0070192 25 0.012
development of primary male sexual characteristics GO:0046546 4 0.011
Mouse
regulation of mitosis GO:0007088 18 0.011
regulation of chromatin modification GO:1903308 2 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
taxis GO:0042330 128 0.011
regulation of protein targeting GO:1903533 3 0.010
deoxyribonucleotide biosynthetic process GO:0009263 1 0.010
regulation of growth GO:0040008 409 0.010
regulation of macromolecule biosynthetic process GO:0010556 189 0.010
membrane invagination GO:0010324 98 0.010
secretion GO:0046903 147 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
regulation of locomotion GO:0040012 161 0.010
cell cycle g1 s phase transition GO:0044843 2 0.010

aspm-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
cardiovascular system disease DOID:1287 0 0.022
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010