Caenorhabditis elegans

3 known processes

aly-2 (CELE_F23B2.6)

Protein ALY-2

aly-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.824
development of primary sexual characteristics GO:0045137 840 0.786
reproductive system development GO:0061458 850 0.642
embryo development ending in birth or egg hatching GO:0009792 2992 0.636
reproductive structure development GO:0048608 850 0.588
hermaphrodite genitalia development GO:0040035 734 0.575
gonad development GO:0008406 840 0.552
locomotion GO:0040011 1634 0.419
sex differentiation GO:0007548 909 0.401
post embryonic development GO:0009791 2152 0.363
organ development GO:0048513 1102 0.336
single organism reproductive process GO:0044702 1196 0.299
genitalia development GO:0048806 741 0.249
developmental process involved in reproduction GO:0003006 1165 0.238
response to chemical GO:0042221 356 0.230
multicellular organismal reproductive process GO:0048609 815 0.229
dna metabolic process GO:0006259 74 0.180
Human
negative regulation of biological process GO:0048519 567 0.178
multicellular organism reproduction GO:0032504 819 0.177
signaling GO:0023052 401 0.170
regulation of multicellular organismal process GO:0051239 726 0.155
growth GO:0040007 562 0.154
nucleobase containing compound metabolic process GO:0006139 406 0.138
Human
response to external stimulus GO:0009605 289 0.121
cell death GO:0008219 547 0.120
transcription from rna polymerase ii promoter GO:0006366 149 0.119
positive regulation of multicellular organismal process GO:0051240 417 0.117
regulation of metabolic process GO:0019222 478 0.105
Human
positive regulation of developmental process GO:0051094 408 0.103
death GO:0016265 547 0.100
organelle organization GO:0006996 783 0.097
catabolic process GO:0009056 318 0.096
organonitrogen compound metabolic process GO:1901564 151 0.095
regulation of developmental process GO:0050793 684 0.095
multi organism reproductive behavior GO:0044705 387 0.092
cellular catabolic process GO:0044248 199 0.090
regulation of response to stimulus GO:0048583 243 0.087
protein complex subunit organization GO:0071822 280 0.085
regulation of multicellular organismal development GO:2000026 317 0.083
dna repair GO:0006281 23 0.081
vesicle mediated transport GO:0016192 852 0.081
regulation of transcription dna templated GO:0006355 164 0.080
Human
cellular response to stress GO:0033554 162 0.079
Human
regulation of biological quality GO:0065008 741 0.079
signal transduction GO:0007165 317 0.078
macromolecule localization GO:0033036 771 0.078
Human Mouse
programmed cell death GO:0012501 500 0.078
body morphogenesis GO:0010171 620 0.078
oviposition GO:0018991 364 0.077
maintenance of location GO:0051235 580 0.075
positive regulation of cellular process GO:0048522 332 0.074
Human
phosphorus metabolic process GO:0006793 232 0.073
lipid localization GO:0010876 573 0.070
endocytosis GO:0006897 819 0.069
multi organism reproductive process GO:0044703 867 0.068
lipid storage GO:0019915 565 0.066
negative regulation of nematode larval development GO:0061064 208 0.064
regulation of nucleic acid templated transcription GO:1903506 165 0.064
Human
macromolecule catabolic process GO:0009057 202 0.064
heterocycle catabolic process GO:0046700 119 0.062
apoptotic process GO:0006915 478 0.062
protein localization GO:0008104 205 0.062
multicellular organism growth GO:0035264 385 0.061
response to organic substance GO:0010033 131 0.061
negative regulation of cellular process GO:0048523 239 0.061
regulation of rna biosynthetic process GO:2001141 165 0.060
Human
single organism signaling GO:0044700 401 0.060
regulation of multicellular organism growth GO:0040014 373 0.059
digestive tract development GO:0048565 122 0.058
organic cyclic compound biosynthetic process GO:1901362 195 0.058
Human
cellular component biogenesis GO:0044085 297 0.057
rna biosynthetic process GO:0032774 169 0.056
Human
regulation of nematode larval development GO:0061062 260 0.055
negative regulation of vulval development GO:0040027 206 0.054
transport GO:0006810 1093 0.053
Human Mouse
negative regulation of post embryonic development GO:0048581 208 0.053
cellular response to organic substance GO:0071310 119 0.051
cellular nitrogen compound biosynthetic process GO:0044271 192 0.050
Human
regulation of vulval development GO:0040028 248 0.049
negative regulation of multicellular organismal process GO:0051241 236 0.049
cellular response to dna damage stimulus GO:0006974 41 0.049
Human
developmental growth GO:0048589 412 0.047
regulation of developmental growth GO:0048638 389 0.046
negative regulation of gene expression epigenetic GO:0045814 2 0.046
intracellular signal transduction GO:0035556 96 0.046
autophagy GO:0006914 29 0.045
reproductive behavior GO:0019098 387 0.045
regulation of macromolecule metabolic process GO:0060255 421 0.044
Human
multi multicellular organism process GO:0044706 390 0.044
vulval development GO:0040025 333 0.043
negative regulation of cellular metabolic process GO:0031324 95 0.043
establishment of localization GO:0051234 1171 0.043
Human Mouse
organelle localization GO:0051640 127 0.042
nervous system development GO:0007399 253 0.042
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.042
nucleic acid templated transcription GO:0097659 169 0.041
Human
cellular response to chemical stimulus GO:0070887 129 0.040
neuron differentiation GO:0030182 217 0.040
gamete generation GO:0007276 461 0.039
single organism localization GO:1902578 518 0.039
positive regulation of rna metabolic process GO:0051254 103 0.037
Human
post embryonic organ development GO:0048569 336 0.037
regulation of molecular function GO:0065009 89 0.036
cellular protein modification process GO:0006464 207 0.036
small molecule metabolic process GO:0044281 186 0.036
rna metabolic process GO:0016070 228 0.035
Human
positive regulation of rna biosynthetic process GO:1902680 102 0.035
Human
cellular component assembly GO:0022607 293 0.035
nucleic acid metabolic process GO:0090304 299 0.034
Human
meiotic nuclear division GO:0007126 300 0.034
positive regulation of developmental growth GO:0048639 354 0.034
gene expression GO:0010467 412 0.034
Human
multi organism behavior GO:0051705 389 0.034
enzyme linked receptor protein signaling pathway GO:0007167 50 0.033
meiotic cell cycle GO:0051321 335 0.033
cellular protein localization GO:0034613 75 0.033
positive regulation of growth GO:0045927 369 0.033
regulation of growth GO:0040008 409 0.033
regulation of cell communication GO:0010646 176 0.033
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.033
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.032
Human
cell morphogenesis GO:0000902 163 0.032
determination of adult lifespan GO:0008340 812 0.032
positive regulation of multicellular organism growth GO:0040018 352 0.032
regulation of organelle organization GO:0033043 164 0.032
single organism organelle organization GO:1902589 501 0.032
aromatic compound biosynthetic process GO:0019438 192 0.031
Human
behavior GO:0007610 527 0.031
regulation of primary metabolic process GO:0080090 292 0.031
Human
regulation of gene expression epigenetic GO:0040029 163 0.031
macromolecular complex assembly GO:0065003 193 0.031
aromatic compound catabolic process GO:0019439 116 0.030
germ cell development GO:0007281 351 0.030
macromolecule modification GO:0043412 218 0.030
positive regulation of catalytic activity GO:0043085 59 0.030
nucleoside phosphate metabolic process GO:0006753 108 0.030
receptor mediated endocytosis GO:0006898 715 0.030
aging GO:0007568 812 0.029
nucleobase containing compound biosynthetic process GO:0034654 184 0.029
Human
multicellular organismal aging GO:0010259 812 0.029
regulation of signaling GO:0023051 172 0.029
negative regulation of macromolecule metabolic process GO:0010605 229 0.029
single fertilization GO:0007338 61 0.028
regulation of post embryonic development GO:0048580 260 0.028
single organism catabolic process GO:0044712 129 0.027
cellular component movement GO:0006928 388 0.027
organic cyclic compound catabolic process GO:1901361 119 0.027
regulation of gene expression GO:0010468 366 0.027
Human
cell division GO:0051301 262 0.027
neurogenesis GO:0022008 236 0.027
carboxylic acid metabolic process GO:0019752 34 0.027
cell proliferation GO:0008283 116 0.026
positive regulation of cellular biosynthetic process GO:0031328 109 0.026
Human
embryonic morphogenesis GO:0048598 152 0.026
transcription dna templated GO:0006351 168 0.026
Human
chromosome organization GO:0051276 104 0.026
protein complex assembly GO:0006461 186 0.026
cytoskeleton organization GO:0007010 339 0.025
regulation of signal transduction GO:0009966 135 0.025
oxoacid metabolic process GO:0043436 47 0.025
regulation of intracellular signal transduction GO:1902531 77 0.025
nucleobase containing compound catabolic process GO:0034655 114 0.025
organic substance catabolic process GO:1901575 294 0.025
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.024
negative regulation of signal transduction GO:0009968 60 0.024
biosynthetic process GO:0009058 323 0.024
Human
cellular component morphogenesis GO:0032989 318 0.024
localization of cell GO:0051674 313 0.024
mitotic sister chromatid segregation GO:0000070 38 0.023
multicellular organismal reproductive behavior GO:0033057 384 0.023
ribonucleotide catabolic process GO:0009261 75 0.023
regulation of localization GO:0032879 194 0.023
cellular macromolecule localization GO:0070727 75 0.023
cellular protein complex assembly GO:0043623 178 0.022
regulation of cellular component organization GO:0051128 248 0.022
nucleotide catabolic process GO:0009166 77 0.022
cellular biosynthetic process GO:0044249 315 0.021
Human
sexual reproduction GO:0019953 546 0.021
cellular localization GO:0051641 360 0.021
Human
ribonucleoside triphosphate catabolic process GO:0009203 72 0.021
protein catabolic process GO:0030163 162 0.021
actin filament based process GO:0030029 191 0.021
myofibril assembly GO:0030239 154 0.021
regulation of cell proliferation GO:0042127 105 0.021
microtubule depolymerization GO:0007019 10 0.021
regulation of apoptotic signaling pathway GO:2001233 1 0.021
generation of neurons GO:0048699 235 0.020
digestive system development GO:0055123 122 0.020
cellular amine metabolic process GO:0044106 15 0.020
cellular response to endogenous stimulus GO:0071495 32 0.019
molting cycle GO:0042303 281 0.019
cell projection morphogenesis GO:0048858 148 0.019
meiotic cell cycle process GO:1903046 170 0.019
protein complex biogenesis GO:0070271 186 0.019
neuron projection development GO:0031175 187 0.019
organelle assembly GO:0070925 214 0.019
dna packaging GO:0006323 7 0.019
microtubule polymerization or depolymerization GO:0031109 22 0.018
glycosyl compound metabolic process GO:1901657 100 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
female gamete generation GO:0007292 254 0.018
chromatin assembly or disassembly GO:0006333 1 0.018
phosphate containing compound metabolic process GO:0006796 232 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.018
regulation of cellular metabolic process GO:0031323 305 0.018
Human
cell cycle GO:0007049 526 0.017
organic acid metabolic process GO:0006082 47 0.017
er nucleus signaling pathway GO:0006984 66 0.017
peptidyl amino acid modification GO:0018193 58 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
regulation of programmed cell death GO:0043067 50 0.017
nucleoside triphosphate catabolic process GO:0009143 72 0.017
neuron development GO:0048666 199 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.017
Human
dna conformation change GO:0071103 11 0.017
cell growth GO:0016049 44 0.016
cellular macromolecule biosynthetic process GO:0034645 247 0.016
Human
oogenesis GO:0048477 229 0.016
fertilization GO:0009566 63 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
cell projection organization GO:0030030 231 0.016
macromolecule biosynthetic process GO:0009059 250 0.016
Human
amine metabolic process GO:0009308 15 0.016
positive regulation of molecular function GO:0044093 61 0.016
dna recombination GO:0006310 19 0.016
Human
microtubule anchoring GO:0034453 8 0.015
organelle fission GO:0048285 363 0.015
cell development GO:0048468 696 0.015
deoxyribonucleotide biosynthetic process GO:0009263 1 0.015
ion transport GO:0006811 113 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
regulation of cell differentiation GO:0045595 81 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
regulation of rna metabolic process GO:0051252 173 0.014
Human
mitotic cell cycle process GO:1903047 194 0.014
purine ribonucleotide metabolic process GO:0009150 95 0.014
heterocycle biosynthetic process GO:0018130 187 0.014
Human
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
Human
attachment of spindle microtubules to kinetochore GO:0008608 8 0.014
head development GO:0060322 1 0.014
regulation of multi organism process GO:0043900 69 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.014
Human
nucleotide metabolic process GO:0009117 108 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
negative regulation of cell communication GO:0010648 61 0.013
anatomical structure formation involved in morphogenesis GO:0048646 250 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.013
pronuclear migration GO:0035046 51 0.013
nucleus localization GO:0051647 55 0.013
cellular amino acid metabolic process GO:0006520 15 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
nucleobase containing small molecule metabolic process GO:0055086 115 0.013
organic substance biosynthetic process GO:1901576 323 0.013
Human
muscle structure development GO:0061061 191 0.013
cell migration GO:0016477 306 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
chemotaxis GO:0006935 120 0.013
asymmetric protein localization GO:0008105 35 0.013
actin cytoskeleton organization GO:0030036 184 0.013
nucleoside metabolic process GO:0009116 99 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.012
regulation of reproductive process GO:2000241 66 0.012
single organism transport GO:0044765 447 0.012
regulation of cellular biosynthetic process GO:0031326 189 0.012
Human
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
Human
nucleoside monophosphate metabolic process GO:0009123 46 0.012
establishment or maintenance of cell polarity GO:0007163 63 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.012
neuron projection morphogenesis GO:0048812 114 0.012
negative regulation of metabolic process GO:0009892 240 0.012
gene silencing GO:0016458 143 0.012
chromatin assembly GO:0031497 1 0.012
ribose phosphate metabolic process GO:0019693 99 0.011
establishment of localization in cell GO:0051649 318 0.011
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
maintenance of protein location in cell GO:0032507 12 0.011
regulation of meiotic cell cycle GO:0051445 136 0.011
positive regulation of transcription dna templated GO:0045893 102 0.011
Human
atp metabolic process GO:0046034 42 0.011
protein metabolic process GO:0019538 422 0.011
internal peptidyl lysine acetylation GO:0018393 3 0.011
establishment of organelle localization GO:0051656 123 0.011
chromatin remodeling GO:0006338 2 0.011
negative regulation of developmental process GO:0051093 227 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of cell death GO:0010941 65 0.011
regulation of macromolecule biosynthetic process GO:0010556 189 0.011
Human
peptidyl lysine acetylation GO:0018394 3 0.011
organophosphate catabolic process GO:0046434 81 0.011
taxis GO:0042330 128 0.011
ribonucleoside catabolic process GO:0042454 77 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
phosphorylation GO:0016310 116 0.011
innate immune response GO:0045087 190 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
cytokinesis GO:0000910 80 0.011
defense response GO:0006952 296 0.011
single organism behavior GO:0044708 83 0.011
muscle cell development GO:0055001 158 0.010
gene silencing by rna GO:0031047 143 0.010
rna interference GO:0016246 137 0.010
regulation of cellular catabolic process GO:0031329 51 0.010
digestive tract morphogenesis GO:0048546 76 0.010
ribonucleotide metabolic process GO:0009259 99 0.010
purine containing compound catabolic process GO:0072523 75 0.010
myosin filament organization GO:0031033 138 0.010
phagocytosis GO:0006909 115 0.010
muscle attachment GO:0016203 3 0.010
cellular macromolecule catabolic process GO:0044265 73 0.010
tube development GO:0035295 126 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.010
negative regulation of response to stimulus GO:0048585 73 0.010

aly-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011