Caenorhabditis elegans

2 known processes

hsp-12.2 (CELE_C14B9.1)

Protein HSP-12.2

hsp-12.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.578
post embryonic development GO:0009791 2152 0.441
Worm
cytoskeleton organization GO:0007010 339 0.396
Mouse
embryo development GO:0009790 3052 0.374
Mouse
body morphogenesis GO:0010171 620 0.342
muscle organ morphogenesis GO:0048644 4 0.339
locomotion GO:0040011 1634 0.307
Human
single organism organelle organization GO:1902589 501 0.284
Mouse
organelle organization GO:0006996 783 0.268
Mouse
muscle contraction GO:0006936 43 0.232
sarcomere organization GO:0045214 10 0.220
anatomical structure formation involved in morphogenesis GO:0048646 250 0.207
Human
reproductive behavior GO:0019098 387 0.206
directional locomotion GO:0033058 14 0.204
anatomical structure homeostasis GO:0060249 11 0.196
Human
endocytosis GO:0006897 819 0.190
regulation of muscle contraction GO:0006937 20 0.168
cell development GO:0048468 696 0.142
Mouse
muscle system process GO:0003012 43 0.141
Zebrafish
positive regulation of multicellular organismal process GO:0051240 417 0.140
Human Mouse
macromolecule localization GO:0033036 771 0.139
regulation of developmental process GO:0050793 684 0.138
Human
regulation of atp catabolic process GO:1903289 3 0.137
multi organism reproductive process GO:0044703 867 0.133
multicellular organism reproduction GO:0032504 819 0.124
phosphate containing compound metabolic process GO:0006796 232 0.123
Mouse
regulation of multicellular organismal process GO:0051239 726 0.120
Human Zebrafish Mouse
multicellular organismal reproductive process GO:0048609 815 0.114
organ development GO:0048513 1102 0.111
Zebrafish Mouse
behavior GO:0007610 527 0.109
Human
development of primary sexual characteristics GO:0045137 840 0.108
genitalia development GO:0048806 741 0.104
multicellular organismal reproductive behavior GO:0033057 384 0.100
vesicle mediated transport GO:0016192 852 0.091
multi multicellular organism process GO:0044706 390 0.090
actin filament based process GO:0030029 191 0.089
Mouse
multi organism reproductive behavior GO:0044705 387 0.086
localization of cell GO:0051674 313 0.085
Human
regulation of muscle system process GO:0090257 20 0.085
Zebrafish
regulation of metabolic process GO:0019222 478 0.084
Mouse
tissue morphogenesis GO:0048729 65 0.084
cellular component assembly involved in morphogenesis GO:0010927 183 0.083
multicellular organism growth GO:0035264 385 0.082
regulation of biological quality GO:0065008 741 0.082
Human Zebrafish
gonad development GO:0008406 840 0.082
regulation of developmental growth GO:0048638 389 0.078
multi organism behavior GO:0051705 389 0.077
regulation of multicellular organism growth GO:0040014 373 0.076
cell motility GO:0048870 313 0.075
Human
myofibril assembly GO:0030239 154 0.073
cellular component biogenesis GO:0044085 297 0.073
Mouse
signal transduction GO:0007165 317 0.073
Human Mouse Worm
organ morphogenesis GO:0009887 67 0.073
Mouse
positive regulation of growth GO:0045927 369 0.071
Mouse
cell migration GO:0016477 306 0.071
Human
positive regulation of rna metabolic process GO:0051254 103 0.070
single organism reproductive process GO:0044702 1196 0.070
lipid localization GO:0010876 573 0.069
sexual reproduction GO:0019953 546 0.069
determination of adult lifespan GO:0008340 812 0.069
Worm
organic substance catabolic process GO:1901575 294 0.069
cellular macromolecule biosynthetic process GO:0034645 247 0.069
feeding behavior GO:0007631 70 0.069
receptor mediated endocytosis GO:0006898 715 0.068
cellular component movement GO:0006928 388 0.067
Human
generation of neurons GO:0048699 235 0.066
cellular component morphogenesis GO:0032989 318 0.065
Mouse
lipid storage GO:0019915 565 0.064
neuron projection development GO:0031175 187 0.062
striated muscle cell differentiation GO:0051146 158 0.061
actin cytoskeleton organization GO:0030036 184 0.060
Mouse
maintenance of location GO:0051235 580 0.058
oviposition GO:0018991 364 0.057
muscle cell differentiation GO:0042692 171 0.056
regulation of primary metabolic process GO:0080090 292 0.056
Mouse
organelle assembly GO:0070925 214 0.056
nervous system development GO:0007399 253 0.055
cell projection organization GO:0030030 231 0.054
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.053
Mouse
negative regulation of cellular process GO:0048523 239 0.053
Mouse
muscle tissue development GO:0060537 1 0.053
developmental process involved in reproduction GO:0003006 1165 0.053
protein metabolic process GO:0019538 422 0.052
Mouse
cellular protein modification process GO:0006464 207 0.051
Mouse
catabolic process GO:0009056 318 0.051
embryonic morphogenesis GO:0048598 152 0.051
Mouse
striated muscle cell development GO:0055002 157 0.051
cellular component assembly GO:0022607 293 0.051
Mouse
reproductive structure development GO:0048608 850 0.050
cell morphogenesis involved in differentiation GO:0000904 112 0.050
Mouse
negative regulation of biological process GO:0048519 567 0.049
Mouse
transport GO:0006810 1093 0.049
actomyosin structure organization GO:0031032 154 0.049
positive regulation of multicellular organism growth GO:0040018 352 0.048
macromolecular complex subunit organization GO:0043933 320 0.048
Mouse
phagocytosis GO:0006909 115 0.048
striated muscle contraction GO:0006941 17 0.047
muscle cell cellular homeostasis GO:0046716 5 0.047
positive regulation of biosynthetic process GO:0009891 109 0.046
Mouse
negative regulation of metabolic process GO:0009892 240 0.044
Mouse
positive regulation of developmental growth GO:0048639 354 0.044
regulation of cellular component organization GO:0051128 248 0.043
Mouse
embryonic body morphogenesis GO:0010172 49 0.043
post embryonic organ development GO:0048569 336 0.043
negative regulation of multicellular organismal process GO:0051241 236 0.043
sensory organ morphogenesis GO:0090596 2 0.042
Mouse
establishment of localization GO:0051234 1171 0.042
regulation of rna metabolic process GO:0051252 173 0.041
positive regulation of developmental process GO:0051094 408 0.041
Human
muscle cell development GO:0055001 158 0.040
protein catabolic process GO:0030163 162 0.040
regulation of nitrogen compound metabolic process GO:0051171 222 0.038
cellular catabolic process GO:0044248 199 0.038
multicellular organismal movement GO:0050879 2 0.038
macromolecule catabolic process GO:0009057 202 0.038
intracellular signal transduction GO:0035556 96 0.038
Human Mouse
system process GO:0003008 136 0.037
Zebrafish
skeletal muscle thin filament assembly GO:0030240 3 0.036
regulation of atpase activity GO:0043462 3 0.035
single organism signaling GO:0044700 401 0.035
Human Mouse Worm
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.034
phosphorus metabolic process GO:0006793 232 0.034
Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.034
protein modification process GO:0036211 207 0.034
Mouse
single organism transport GO:0044765 447 0.033
nucleic acid metabolic process GO:0090304 299 0.032
negative regulation of developmental process GO:0051093 227 0.032
protein localization GO:0008104 205 0.031
regulation of growth GO:0040008 409 0.031
Mouse
regulation of system process GO:0044057 27 0.031
Zebrafish
ovulation GO:0030728 33 0.031
aging GO:0007568 812 0.030
Worm
sex differentiation GO:0007548 909 0.030
response to external biotic stimulus GO:0043207 101 0.030
Human Worm
backward locomotion GO:0043057 11 0.029
regulation of phosphate metabolic process GO:0019220 81 0.029
Mouse
neurogenesis GO:0022008 236 0.029
macromolecule biosynthetic process GO:0009059 250 0.029
Mouse
cellular protein metabolic process GO:0044267 279 0.028
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.028
eating behavior GO:0042755 59 0.028
biosynthetic process GO:0009058 323 0.028
Mouse
multicellular organismal aging GO:0010259 812 0.028
Worm
cell cycle process GO:0022402 482 0.028
response to chemical GO:0042221 356 0.027
Human Zebrafish Mouse Worm
female gamete generation GO:0007292 254 0.027
regulation of cellular metabolic process GO:0031323 305 0.027
Mouse
phosphorylation GO:0016310 116 0.026
Mouse
cellular biosynthetic process GO:0044249 315 0.026
Mouse
pharyngeal pumping GO:0043050 58 0.026
cellular response to unfolded protein GO:0034620 71 0.026
Worm
protein complex subunit organization GO:0071822 280 0.025
Mouse
gamete generation GO:0007276 461 0.025
inductive cell migration GO:0040039 145 0.025
signaling GO:0023052 401 0.024
Human Mouse Worm
cellular response to topologically incorrect protein GO:0035967 76 0.024
Worm
muscle structure development GO:0061061 191 0.024
Mouse
neuron recognition GO:0008038 83 0.023
cellular protein complex assembly GO:0043623 178 0.023
Mouse
cell substrate adhesion GO:0031589 1 0.023
tissue development GO:0009888 112 0.023
Mouse
striated muscle myosin thick filament assembly GO:0071688 138 0.023
immune response GO:0006955 192 0.023
single organism localization GO:1902578 518 0.022
axon development GO:0061564 163 0.022
nucleoside phosphate metabolic process GO:0006753 108 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.022
cell recognition GO:0008037 85 0.022
response to topologically incorrect protein GO:0035966 82 0.022
Worm
negative regulation of purine nucleotide metabolic process GO:1900543 5 0.021
programmed cell death GO:0012501 500 0.020
Mouse
single organism catabolic process GO:0044712 129 0.020
response to unfolded protein GO:0006986 71 0.020
Worm
neuron development GO:0048666 199 0.020
regulation of nucleotide catabolic process GO:0030811 35 0.020
regulation of response to stimulus GO:0048583 243 0.020
Human Mouse
cellular macromolecular complex assembly GO:0034622 184 0.020
Mouse
reproductive system development GO:0061458 850 0.019
cellular nitrogen compound biosynthetic process GO:0044271 192 0.019
phagocytosis engulfment GO:0006911 98 0.019
developmental growth GO:0048589 412 0.019
cellular response to stress GO:0033554 162 0.018
Mouse Worm
response to external stimulus GO:0009605 289 0.018
Human Worm
regulation of purine nucleotide catabolic process GO:0033121 35 0.018
regulation of organelle organization GO:0033043 164 0.018
protein complex assembly GO:0006461 186 0.018
Mouse
regulation of multi organism process GO:0043900 69 0.018
positive regulation of cellular biosynthetic process GO:0031328 109 0.018
Mouse
organelle fission GO:0048285 363 0.017
macromolecule modification GO:0043412 218 0.017
Mouse
death GO:0016265 547 0.017
Mouse
meiotic nuclear division GO:0007126 300 0.017
mechanosensory behavior GO:0007638 25 0.017
myosin filament organization GO:0031033 138 0.017
cell cycle GO:0007049 526 0.017
actin filament based movement GO:0030048 4 0.016
growth GO:0040007 562 0.016
Mouse
defecation GO:0030421 47 0.016
carbohydrate derivative metabolic process GO:1901135 141 0.016
myosin filament assembly GO:0031034 138 0.016
cell morphogenesis GO:0000902 163 0.016
Mouse
regulation of muscle cell differentiation GO:0051147 1 0.016
apoptotic cell clearance GO:0043277 111 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.016
regulation of atp metabolic process GO:1903578 5 0.016
axonal fasciculation GO:0007413 79 0.016
regulation of cellular biosynthetic process GO:0031326 189 0.016
Mouse
membrane organization GO:0061024 135 0.016
negative regulation of post embryonic development GO:0048581 208 0.016
regulation of nematode larval development GO:0061062 260 0.016
positive regulation of cellular process GO:0048522 332 0.016
Human Mouse
meiotic cell cycle GO:0051321 335 0.015
cell matrix adhesion GO:0007160 1 0.015
regulation of purine nucleotide metabolic process GO:1900542 37 0.015
regulation of phosphorus metabolic process GO:0051174 81 0.015
Mouse
membrane invagination GO:0010324 98 0.015
regulation of macromolecule metabolic process GO:0060255 421 0.015
Mouse
cilium assembly GO:0042384 28 0.015
excretion GO:0007588 49 0.015
carbohydrate derivative catabolic process GO:1901136 82 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
Mouse
regulation of biosynthetic process GO:0009889 189 0.015
Mouse
organonitrogen compound metabolic process GO:1901564 151 0.014
germ cell development GO:0007281 351 0.014
neuron differentiation GO:0030182 217 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
Mouse
positive regulation of phosphate metabolic process GO:0045937 56 0.014
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.014
macromolecular complex assembly GO:0065003 193 0.014
Mouse
engulfment of apoptotic cell GO:0043652 94 0.014
canonical wnt signaling pathway GO:0060070 3 0.013
skeletal muscle organ development GO:0060538 3 0.013
response to abiotic stimulus GO:0009628 152 0.013
Zebrafish Mouse Worm
organophosphate catabolic process GO:0046434 81 0.013
cell proliferation GO:0008283 116 0.013
small molecule metabolic process GO:0044281 186 0.013
hermaphrodite genitalia development GO:0040035 734 0.013
negative regulation of vulval development GO:0040027 206 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.012
muscle organ development GO:0007517 26 0.012
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.012
negative regulation of nucleoside metabolic process GO:0045978 5 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
regulation of post embryonic development GO:0048580 260 0.011
mating GO:0007618 34 0.011
er nucleus signaling pathway GO:0006984 66 0.011
Worm
atp metabolic process GO:0046034 42 0.011
regulation of catabolic process GO:0009894 57 0.011
regulation of macromolecule biosynthetic process GO:0010556 189 0.011
Mouse
protein complex biogenesis GO:0070271 186 0.011
Mouse
positive regulation of transcription dna templated GO:0045893 102 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
protein phosphorylation GO:0006468 85 0.011
Mouse
bmp signaling pathway GO:0030509 3 0.011
adult locomotory behavior GO:0008344 1 0.011
organic substance transport GO:0071702 113 0.011
negative regulation of transmembrane transport GO:0034763 3 0.011
actin filament organization GO:0007015 21 0.010
Mouse
regulation of intracellular signal transduction GO:1902531 77 0.010
Mouse
regulation of gene expression GO:0010468 366 0.010
Mouse
purine nucleoside monophosphate catabolic process GO:0009128 28 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.010
negative regulation of nematode larval development GO:0061064 208 0.010
regulation of canonical wnt signaling pathway GO:0060828 1 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010

hsp-12.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.083
muscle tissue disease DOID:66 0 0.083
myopathy DOID:423 0 0.083
disease of anatomical entity DOID:7 0 0.083
Human
heart disease DOID:114 0 0.083
muscular disease DOID:0080000 0 0.083
cardiomyopathy DOID:0050700 0 0.083
cardiovascular system disease DOID:1287 0 0.083
intrinsic cardiomyopathy DOID:0060036 0 0.018
hypertrophic cardiomyopathy DOID:11984 0 0.018
nervous system disease DOID:863 0 0.013
Human