Caenorhabditis elegans

5 known processes

hex-2 (CELE_C14C11.3)

Protein HEX-2

hex-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.325
cell migration GO:0016477 306 0.230
aging GO:0007568 812 0.221
cytoskeleton organization GO:0007010 339 0.208
vesicle mediated transport GO:0016192 852 0.182
locomotion GO:0040011 1634 0.169
organelle fission GO:0048285 363 0.159
endocytosis GO:0006897 819 0.154
transport GO:0006810 1093 0.151
growth GO:0040007 562 0.149
organelle organization GO:0006996 783 0.134
embryo development GO:0009790 3052 0.131
multicellular organismal aging GO:0010259 812 0.129
signaling GO:0023052 401 0.127
receptor mediated endocytosis GO:0006898 715 0.114
mitotic cell cycle process GO:1903047 194 0.112
regulation of growth GO:0040008 409 0.107
multicellular organism reproduction GO:0032504 819 0.103
multi organism reproductive process GO:0044703 867 0.102
establishment of spindle localization GO:0051293 51 0.099
regulation of biological quality GO:0065008 741 0.098
spindle localization GO:0051653 51 0.098
signal transduction GO:0007165 317 0.093
single organism reproductive process GO:0044702 1196 0.092
organ development GO:0048513 1102 0.091
development of primary sexual characteristics GO:0045137 840 0.088
sex differentiation GO:0007548 909 0.087
organelle localization GO:0051640 127 0.087
cell cycle GO:0007049 526 0.085
regulation of cell communication GO:0010646 176 0.084
regulation of signaling GO:0023051 172 0.083
embryo development ending in birth or egg hatching GO:0009792 2992 0.082
single organism signaling GO:0044700 401 0.082
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.082
developmental maturation GO:0021700 26 0.081
determination of adult lifespan GO:0008340 812 0.080
protein modification process GO:0036211 207 0.079
single organism localization GO:1902578 518 0.079
cellular component movement GO:0006928 388 0.079
oogenesis GO:0048477 229 0.077
macromolecule localization GO:0033036 771 0.073
developmental process involved in reproduction GO:0003006 1165 0.073
lipid storage GO:0019915 565 0.072
microtubule based process GO:0007017 182 0.072
gonad development GO:0008406 840 0.070
cell development GO:0048468 696 0.070
protein complex subunit organization GO:0071822 280 0.070
cell death GO:0008219 547 0.068
response to external biotic stimulus GO:0043207 101 0.067
female gamete generation GO:0007292 254 0.067
maintenance of location GO:0051235 580 0.067
protein catabolic process GO:0030163 162 0.065
response to biotic stimulus GO:0009607 101 0.063
cell surface receptor signaling pathway GO:0007166 149 0.061
phagocytosis GO:0006909 115 0.060
protein metabolic process GO:0019538 422 0.060
anatomical structure formation involved in morphogenesis GO:0048646 250 0.059
regulation of response to stimulus GO:0048583 243 0.059
positive regulation of multicellular organism growth GO:0040018 352 0.059
nucleobase containing compound metabolic process GO:0006139 406 0.058
regulation of signal transduction GO:0009966 135 0.058
reproductive system development GO:0061458 850 0.058
catabolic process GO:0009056 318 0.058
lipid localization GO:0010876 573 0.057
macromolecular complex subunit organization GO:0043933 320 0.057
organic substance catabolic process GO:1901575 294 0.056
meiotic nuclear division GO:0007126 300 0.056
response to wounding GO:0009611 4 0.054
positive regulation of developmental growth GO:0048639 354 0.054
gamete generation GO:0007276 461 0.054
cellular response to stress GO:0033554 162 0.053
protein complex assembly GO:0006461 186 0.053
striated muscle cell development GO:0055002 157 0.053
developmental growth GO:0048589 412 0.051
embryonic morphogenesis GO:0048598 152 0.049
multicellular organismal reproductive process GO:0048609 815 0.049
cellular protein complex assembly GO:0043623 178 0.048
establishment or maintenance of cell polarity GO:0007163 63 0.048
multicellular organism growth GO:0035264 385 0.047
macromolecule catabolic process GO:0009057 202 0.047
regulation of locomotion GO:0040012 161 0.046
single organism transport GO:0044765 447 0.046
tube morphogenesis GO:0035239 79 0.046
multicellular organismal reproductive behavior GO:0033057 384 0.045
cellular response to organic substance GO:0071310 119 0.045
protein phosphorylation GO:0006468 85 0.045
reproductive structure development GO:0048608 850 0.044
cell motility GO:0048870 313 0.044
immune response GO:0006955 192 0.044
head development GO:0060322 1 0.043
mitotic nuclear division GO:0007067 89 0.042
actomyosin structure organization GO:0031032 154 0.042
positive regulation of developmental process GO:0051094 408 0.041
establishment of localization GO:0051234 1171 0.041
death GO:0016265 547 0.041
chromosome segregation GO:0007059 180 0.040
digestive tract morphogenesis GO:0048546 76 0.040
cellular macromolecular complex assembly GO:0034622 184 0.040
positive regulation of growth GO:0045927 369 0.039
regulation of multicellular organismal process GO:0051239 726 0.039
regulation of multicellular organism growth GO:0040014 373 0.038
response to other organism GO:0051707 101 0.038
defense response GO:0006952 296 0.038
localization of cell GO:0051674 313 0.038
cellular component biogenesis GO:0044085 297 0.037
apoptotic process GO:0006915 478 0.036
actin filament based process GO:0030029 191 0.036
nervous system development GO:0007399 253 0.036
myofibril assembly GO:0030239 154 0.035
defense response to other organism GO:0098542 100 0.034
body morphogenesis GO:0010171 620 0.034
cellular component assembly GO:0022607 293 0.034
peptidyl tyrosine phosphorylation GO:0018108 2 0.033
membrane organization GO:0061024 135 0.032
cellular protein metabolic process GO:0044267 279 0.032
multi organism behavior GO:0051705 389 0.031
myosin filament assembly GO:0031034 138 0.031
single organism catabolic process GO:0044712 129 0.031
myosin filament organization GO:0031033 138 0.030
apoptotic cell clearance GO:0043277 111 0.030
muscle cell differentiation GO:0042692 171 0.030
collagen and cuticulin based cuticle development GO:0040002 99 0.029
cytokinesis GO:0000910 80 0.029
regulation of developmental process GO:0050793 684 0.029
programmed cell death GO:0012501 500 0.028
negative regulation of biological process GO:0048519 567 0.028
response to bacterium GO:0009617 86 0.028
establishment of mitotic spindle localization GO:0040001 41 0.028
organic substance biosynthetic process GO:1901576 323 0.028
striated muscle cell differentiation GO:0051146 158 0.028
macromolecule modification GO:0043412 218 0.027
regulation of developmental growth GO:0048638 389 0.027
cellular component morphogenesis GO:0032989 318 0.027
cellular component assembly involved in morphogenesis GO:0010927 183 0.027
reproductive behavior GO:0019098 387 0.027
organelle assembly GO:0070925 214 0.027
engulfment of apoptotic cell GO:0043652 94 0.027
behavior GO:0007610 527 0.026
multi multicellular organism process GO:0044706 390 0.026
cuticle development GO:0042335 100 0.026
meiotic chromosome segregation GO:0045132 139 0.026
single organism organelle organization GO:1902589 501 0.026
digestive tract development GO:0048565 122 0.026
rna localization GO:0006403 3 0.025
actin cytoskeleton organization GO:0030036 184 0.025
regulation of metabolic process GO:0019222 478 0.025
genitalia development GO:0048806 741 0.025
oocyte construction GO:0007308 2 0.024
neurogenesis GO:0022008 236 0.024
phosphorus metabolic process GO:0006793 232 0.024
cell cycle process GO:0022402 482 0.024
macromolecular complex assembly GO:0065003 193 0.023
single organism cellular localization GO:1902580 72 0.023
negative regulation of response to stimulus GO:0048585 73 0.023
nucleotide sugar metabolic process GO:0009225 6 0.022
tube development GO:0035295 126 0.022
protein complex biogenesis GO:0070271 186 0.022
small molecule metabolic process GO:0044281 186 0.022
chromosome organization GO:0051276 104 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
cell proliferation GO:0008283 116 0.021
single organism behavior GO:0044708 83 0.021
phosphate containing compound metabolic process GO:0006796 232 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
oocyte development GO:0048599 44 0.021
digestive system development GO:0055123 122 0.021
regulation of molecular function GO:0065009 89 0.020
negative regulation of cellular process GO:0048523 239 0.020
defense response to bacterium GO:0042742 86 0.020
formation of infection structure on or near host GO:0075015 5 0.020
muscle cell development GO:0055001 158 0.020
phagocytosis engulfment GO:0006911 98 0.020
hermaphrodite genitalia development GO:0040035 734 0.020
negative regulation of developmental process GO:0051093 227 0.020
protein localization GO:0008104 205 0.019
response to abiotic stimulus GO:0009628 152 0.019
regulation of organelle organization GO:0033043 164 0.019
cellular biosynthetic process GO:0044249 315 0.018
carbohydrate derivative metabolic process GO:1901135 141 0.018
membrane invagination GO:0010324 98 0.018
signal transduction by phosphorylation GO:0023014 31 0.018
meiotic cell cycle GO:0051321 335 0.018
establishment of organelle localization GO:0051656 123 0.018
oviposition GO:0018991 364 0.017
cellular amino acid metabolic process GO:0006520 15 0.017
biosynthetic process GO:0009058 323 0.017
spindle organization GO:0007051 92 0.017
regulation of localization GO:0032879 194 0.017
meiotic cell cycle process GO:1903046 170 0.017
positive regulation of multicellular organismal process GO:0051240 417 0.017
organonitrogen compound metabolic process GO:1901564 151 0.016
mapk cascade GO:0000165 31 0.016
oxoacid metabolic process GO:0043436 47 0.016
response to organic substance GO:0010033 131 0.016
innate immune response GO:0045087 190 0.016
nucleic acid templated transcription GO:0097659 169 0.015
mitotic spindle organization GO:0007052 81 0.015
regulation of apoptotic signaling pathway GO:2001233 1 0.015
cellular protein modification process GO:0006464 207 0.015
muscle tissue development GO:0060537 1 0.015
regulation of phosphorus metabolic process GO:0051174 81 0.015
nucleobase containing compound biosynthetic process GO:0034654 184 0.014
germ cell development GO:0007281 351 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
nucleic acid metabolic process GO:0090304 299 0.014
cytoskeleton dependent cytokinesis GO:0061640 35 0.014
regulation of cell migration GO:0030334 55 0.014
tissue morphogenesis GO:0048729 65 0.014
spermatogenesis GO:0007283 41 0.014
negative regulation of organelle organization GO:0010639 20 0.014
cell morphogenesis GO:0000902 163 0.013
response to chemical GO:0042221 356 0.013
gene expression GO:0010467 412 0.013
negative regulation of signaling GO:0023057 61 0.013
regulation of macromolecule metabolic process GO:0060255 421 0.013
cellular protein localization GO:0034613 75 0.013
negative regulation of signal transduction GO:0009968 60 0.013
intracellular receptor signaling pathway GO:0030522 2 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
carbohydrate derivative catabolic process GO:1901136 82 0.013
cell division GO:0051301 262 0.013
rna biosynthetic process GO:0032774 169 0.013
phosphorylation GO:0016310 116 0.012
nucleus organization GO:0006997 38 0.012
amine metabolic process GO:0009308 15 0.012
male gamete generation GO:0048232 41 0.012
dna metabolic process GO:0006259 74 0.012
defense response to gram negative bacterium GO:0050829 64 0.012
response to external stimulus GO:0009605 289 0.012
positive regulation of cellular process GO:0048522 332 0.012
organic acid metabolic process GO:0006082 47 0.012
aromatic compound biosynthetic process GO:0019438 192 0.012
cellular localization GO:0051641 360 0.012
carboxylic acid metabolic process GO:0019752 34 0.012
muscle structure development GO:0061061 191 0.011
gene silencing by rna GO:0031047 143 0.011
cellular amine metabolic process GO:0044106 15 0.011
molting cycle GO:0042303 281 0.011
peptidyl amino acid modification GO:0018193 58 0.011
gene silencing GO:0016458 143 0.011
cell maturation GO:0048469 26 0.011
cellular nitrogen compound biosynthetic process GO:0044271 192 0.011
sexual reproduction GO:0019953 546 0.011

hex-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.025
muscular disease DOID:0080000 0 0.020
muscular dystrophy DOID:9884 0 0.020
myopathy DOID:423 0 0.020
muscle tissue disease DOID:66 0 0.020
congenital muscular dystrophy DOID:0050557 0 0.020