Caenorhabditis elegans

10 known processes

C16B8.4 (CELE_C16B8.4)

Protein C16B8.4

C16B8.4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2152 0.249
regulation of multicellular organismal development GO:2000026 317 0.212
embryo development ending in birth or egg hatching GO:0009792 2992 0.180
locomotion GO:0040011 1634 0.158
embryo development GO:0009790 3052 0.149
regulation of developmental process GO:0050793 684 0.145
response to external stimulus GO:0009605 289 0.140
multicellular organism reproduction GO:0032504 819 0.129
regulation of multicellular organismal process GO:0051239 726 0.123
multicellular organismal reproductive behavior GO:0033057 384 0.123
organ development GO:0048513 1102 0.116
sensory organ morphogenesis GO:0090596 2 0.114
multi organism reproductive process GO:0044703 867 0.112
transport GO:0006810 1093 0.109
negative regulation of developmental process GO:0051093 227 0.107
signaling GO:0023052 401 0.105
growth GO:0040007 562 0.103
multicellular organismal reproductive process GO:0048609 815 0.103
muscle tissue development GO:0060537 1 0.102
behavior GO:0007610 527 0.098
cellular biosynthetic process GO:0044249 315 0.093
regulation of nematode larval development GO:0061062 260 0.092
positive regulation of multicellular organismal process GO:0051240 417 0.090
cellular component movement GO:0006928 388 0.087
biosynthetic process GO:0009058 323 0.086
endocytosis GO:0006897 819 0.086
establishment of localization GO:0051234 1171 0.084
sex differentiation GO:0007548 909 0.084
single organism reproductive process GO:0044702 1196 0.083
regulation of locomotion GO:0040012 161 0.082
negative regulation of multicellular organismal process GO:0051241 236 0.082
generation of neurons GO:0048699 235 0.077
body morphogenesis GO:0010171 620 0.077
epithelial tube morphogenesis GO:0060562 1 0.076
head development GO:0060322 1 0.073
regulation of growth GO:0040008 409 0.072
nucleic acid templated transcription GO:0097659 169 0.071
heterocycle biosynthetic process GO:0018130 187 0.071
development of primary sexual characteristics GO:0045137 840 0.070
signal transduction GO:0007165 317 0.070
cell cycle process GO:0022402 482 0.069
negative regulation of biological process GO:0048519 567 0.069
anatomical structure formation involved in morphogenesis GO:0048646 250 0.065
positive regulation of transcription dna templated GO:0045893 102 0.065
developmental process involved in reproduction GO:0003006 1165 0.064
post embryonic organ development GO:0048569 336 0.063
multi organism reproductive behavior GO:0044705 387 0.063
cell morphogenesis involved in differentiation GO:0000904 112 0.063
regulation of cellular biosynthetic process GO:0031326 189 0.063
hermaphrodite genitalia development GO:0040035 734 0.061
regulation of gene expression GO:0010468 366 0.059
vesicle mediated transport GO:0016192 852 0.059
multi organism behavior GO:0051705 389 0.059
macromolecule biosynthetic process GO:0009059 250 0.058
regulation of post embryonic development GO:0048580 260 0.058
cellular macromolecule biosynthetic process GO:0034645 247 0.058
regulation of transcription dna templated GO:0006355 164 0.057
multi multicellular organism process GO:0044706 390 0.057
genitalia development GO:0048806 741 0.057
positive regulation of developmental process GO:0051094 408 0.056
nucleic acid metabolic process GO:0090304 299 0.056
regulation of cellular component organization GO:0051128 248 0.055
reproductive structure development GO:0048608 850 0.055
cell development GO:0048468 696 0.052
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.052
negative regulation of post embryonic development GO:0048581 208 0.051
gene expression GO:0010467 412 0.050
developmental growth GO:0048589 412 0.050
embryonic morphogenesis GO:0048598 152 0.050
maintenance of location GO:0051235 580 0.050
protein metabolic process GO:0019538 422 0.049
neurogenesis GO:0022008 236 0.049
determination of adult lifespan GO:0008340 812 0.049
receptor mediated endocytosis GO:0006898 715 0.049
lipid storage GO:0019915 565 0.048
regulation of biological quality GO:0065008 741 0.048
vulval development GO:0040025 333 0.048
chemotaxis GO:0006935 120 0.048
single organism localization GO:1902578 518 0.047
single organism behavior GO:0044708 83 0.047
taxis GO:0042330 128 0.047
cell motility GO:0048870 313 0.047
tissue development GO:0009888 112 0.047
oviposition GO:0018991 364 0.046
regulation of vulval development GO:0040028 248 0.045
nervous system development GO:0007399 253 0.045
reproductive system development GO:0061458 850 0.045
macromolecule localization GO:0033036 771 0.045
response to mechanical stimulus GO:0009612 28 0.045
negative regulation of vulval development GO:0040027 206 0.044
positive regulation of neurogenesis GO:0050769 4 0.044
cell morphogenesis GO:0000902 163 0.044
positive regulation of growth GO:0045927 369 0.044
regulation of nitrogen compound metabolic process GO:0051171 222 0.043
cell surface receptor signaling pathway GO:0007166 149 0.043
response to abiotic stimulus GO:0009628 152 0.042
negative regulation of metabolic process GO:0009892 240 0.042
cell migration GO:0016477 306 0.041
transcription dna templated GO:0006351 168 0.041
epithelium development GO:0060429 68 0.041
establishment of localization in cell GO:0051649 318 0.041
single organism signaling GO:0044700 401 0.041
nucleobase containing compound metabolic process GO:0006139 406 0.040
muscle cell development GO:0055001 158 0.040
negative regulation of gene expression GO:0010629 217 0.040
lipid localization GO:0010876 573 0.039
gonad development GO:0008406 840 0.039
regulation of epithelial cell proliferation GO:0050678 1 0.039
nucleobase containing compound biosynthetic process GO:0034654 184 0.039
detection of external stimulus GO:0009581 4 0.039
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.039
reproductive behavior GO:0019098 387 0.038
regulation of cellular metabolic process GO:0031323 305 0.038
regulation of multicellular organism growth GO:0040014 373 0.037
single organism transport GO:0044765 447 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.037
regulation of developmental growth GO:0048638 389 0.037
regulation of response to stimulus GO:0048583 243 0.037
regulation of metabolic process GO:0019222 478 0.037
organelle organization GO:0006996 783 0.037
regulation of macromolecule biosynthetic process GO:0010556 189 0.036
rna biosynthetic process GO:0032774 169 0.036
organic substance biosynthetic process GO:1901576 323 0.036
system process GO:0003008 136 0.036
regulation of macromolecule metabolic process GO:0060255 421 0.036
cell division GO:0051301 262 0.035
tube development GO:0035295 126 0.035
localization of cell GO:0051674 313 0.035
positive regulation of multicellular organism growth GO:0040018 352 0.035
aging GO:0007568 812 0.034
canonical wnt signaling pathway GO:0060070 3 0.034
axon development GO:0061564 163 0.034
regulation of cell cycle GO:0051726 194 0.034
regulation of cell communication GO:0010646 176 0.034
multicellular organismal aging GO:0010259 812 0.034
muscle organ morphogenesis GO:0048644 4 0.033
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.033
positive regulation of macromolecule metabolic process GO:0010604 149 0.033
neuron development GO:0048666 199 0.033
response to wounding GO:0009611 4 0.033
negative regulation of macromolecule metabolic process GO:0010605 229 0.033
regulation of biosynthetic process GO:0009889 189 0.032
organ morphogenesis GO:0009887 67 0.032
positive regulation of organ growth GO:0046622 4 0.032
programmed cell death GO:0012501 500 0.031
cellular component morphogenesis GO:0032989 318 0.031
myofibril assembly GO:0030239 154 0.031
cellular localization GO:0051641 360 0.031
regulation of nucleic acid templated transcription GO:1903506 165 0.030
positive regulation of metabolic process GO:0009893 187 0.030
transcription from rna polymerase ii promoter GO:0006366 149 0.030
aromatic compound biosynthetic process GO:0019438 192 0.030
regulation of rna metabolic process GO:0051252 173 0.030
response to chemical GO:0042221 356 0.029
molting cycle GO:0042303 281 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.028
neuron differentiation GO:0030182 217 0.028
axon guidance GO:0007411 82 0.028
positive regulation of cellular metabolic process GO:0031325 178 0.028
negative regulation of nematode larval development GO:0061064 208 0.028
cytoskeleton organization GO:0007010 339 0.028
negative regulation of neurogenesis GO:0050768 4 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
cellular component assembly GO:0022607 293 0.028
striated muscle cell differentiation GO:0051146 158 0.028
epithelial cell proliferation GO:0050673 1 0.027
negative regulation of cellular process GO:0048523 239 0.027
regulation of localization GO:0032879 194 0.026
cell projection organization GO:0030030 231 0.026
skeletal muscle organ development GO:0060538 3 0.026
regulation of signaling GO:0023051 172 0.025
positive regulation of rna biosynthetic process GO:1902680 102 0.025
positive regulation of neuron differentiation GO:0045666 4 0.025
actin cytoskeleton organization GO:0030036 184 0.025
cellular macromolecular complex assembly GO:0034622 184 0.025
neuron projection development GO:0031175 187 0.025
regulation of nervous system development GO:0051960 41 0.025
regulation of cell development GO:0060284 49 0.025
cellular protein metabolic process GO:0044267 279 0.025
cell cycle GO:0007049 526 0.024
positive regulation of developmental growth GO:0048639 354 0.024
protein complex subunit organization GO:0071822 280 0.024
macromolecule modification GO:0043412 218 0.024
negative regulation of neuron differentiation GO:0045665 4 0.024
cellular nitrogen compound biosynthetic process GO:0044271 192 0.024
positive regulation of cellular process GO:0048522 332 0.024
mechanosensory behavior GO:0007638 25 0.024
cellular component biogenesis GO:0044085 297 0.023
regulation of primary metabolic process GO:0080090 292 0.023
rna metabolic process GO:0016070 228 0.023
cell cell signaling GO:0007267 118 0.023
single organism organelle organization GO:1902589 501 0.022
neurological system process GO:0050877 53 0.022
regulation of rna biosynthetic process GO:2001141 165 0.022
sexual reproduction GO:0019953 546 0.022
organelle fission GO:0048285 363 0.022
muscle structure development GO:0061061 191 0.022
multicellular organism growth GO:0035264 385 0.022
actin filament based process GO:0030029 191 0.021
positive regulation of signaling GO:0023056 66 0.021
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.021
death GO:0016265 547 0.021
female gamete generation GO:0007292 254 0.020
tube morphogenesis GO:0035239 79 0.020
regulation of cell proliferation GO:0042127 105 0.019
positive regulation of rna metabolic process GO:0051254 103 0.019
muscle cell differentiation GO:0042692 171 0.019
organelle assembly GO:0070925 214 0.019
positive regulation of gene expression GO:0010628 112 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.019
regulation of neurogenesis GO:0050767 40 0.019
ovulation GO:0030728 33 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.018
regionalization GO:0003002 31 0.018
neuron projection guidance GO:0097485 82 0.018
organonitrogen compound metabolic process GO:1901564 151 0.018
sensory perception GO:0007600 27 0.018
inductive cell migration GO:0040039 145 0.018
regulation of neuron differentiation GO:0045664 40 0.018
neuron projection morphogenesis GO:0048812 114 0.017
cell proliferation GO:0008283 116 0.017
regulation of cytoskeleton organization GO:0051493 41 0.017
response to external biotic stimulus GO:0043207 101 0.017
myosin filament organization GO:0031033 138 0.017
neuromuscular junction development GO:0007528 2 0.017
cellular protein modification process GO:0006464 207 0.017
male anatomical structure morphogenesis GO:0090598 78 0.017
cell recognition GO:0008037 85 0.017
single organism catabolic process GO:0044712 129 0.016
hormone transport GO:0009914 2 0.016
muscle organ development GO:0007517 26 0.016
positive regulation of cell communication GO:0010647 69 0.016
cell type specific apoptotic process GO:0097285 4 0.016
striated muscle cell development GO:0055002 157 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
cell death GO:0008219 547 0.016
cell fate commitment GO:0045165 139 0.016
phosphate containing compound metabolic process GO:0006796 232 0.016
phosphorus metabolic process GO:0006793 232 0.016
regulation of organ morphogenesis GO:2000027 4 0.015
regulation of cell differentiation GO:0045595 81 0.015
cell projection morphogenesis GO:0048858 148 0.015
regulation of organelle organization GO:0033043 164 0.015
immune response GO:0006955 192 0.015
development of primary male sexual characteristics GO:0046546 4 0.015
regulation of cell cycle process GO:0010564 145 0.015
neuron recognition GO:0008038 83 0.015
gamete generation GO:0007276 461 0.015
negative regulation of rna biosynthetic process GO:1902679 53 0.015
germ cell development GO:0007281 351 0.015
positive regulation of phosphorus metabolic process GO:0010562 56 0.015
positive regulation of phosphate metabolic process GO:0045937 56 0.015
organic cyclic compound biosynthetic process GO:1901362 195 0.014
negative regulation of cellular biosynthetic process GO:0031327 65 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
muscle attachment GO:0016203 3 0.014
gastrulation GO:0007369 58 0.014
male sex differentiation GO:0046661 86 0.014
cellular response to stress GO:0033554 162 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
apoptotic process GO:0006915 478 0.014
regulation of cell motility GO:2000145 57 0.014
protein complex biogenesis GO:0070271 186 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.014
phosphorylation GO:0016310 116 0.014
negative regulation of nucleic acid templated transcription GO:1903507 53 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
positive regulation of nucleic acid templated transcription GO:1903508 102 0.013
rna interference GO:0016246 137 0.013
protein modification process GO:0036211 207 0.013
adult locomotory behavior GO:0008344 1 0.013
oogenesis GO:0048477 229 0.013
response to organic substance GO:0010033 131 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.013
oxoacid metabolic process GO:0043436 47 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
synaptic transmission GO:0007268 106 0.013
tissue morphogenesis GO:0048729 65 0.013
detection of abiotic stimulus GO:0009582 4 0.013
establishment of mitotic spindle localization GO:0040001 41 0.013
ras protein signal transduction GO:0007265 31 0.013
regulation of muscle cell differentiation GO:0051147 1 0.013
phagocytosis GO:0006909 115 0.013
negative regulation of rna metabolic process GO:0051253 53 0.013
negative regulation of biosynthetic process GO:0009890 65 0.012
macromolecular complex assembly GO:0065003 193 0.012
positive regulation of response to stimulus GO:0048584 55 0.012
sex determination GO:0007530 60 0.012
protein localization GO:0008104 205 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
negative regulation of cell communication GO:0010648 61 0.012
pigmentation GO:0043473 2 0.012
cell substrate adhesion GO:0031589 1 0.012
regulation of hormone secretion GO:0046883 2 0.012
regulation of gene expression epigenetic GO:0040029 163 0.012
cell part morphogenesis GO:0032990 152 0.012
regulation of canonical wnt signaling pathway GO:0060828 1 0.012
meiotic cell cycle GO:0051321 335 0.012
bmp signaling pathway GO:0030509 3 0.012
muscle fiber development GO:0048747 2 0.012
cellular protein complex assembly GO:0043623 178 0.012
digestive system development GO:0055123 122 0.012
regulation of cell death GO:0010941 65 0.012
myosin filament assembly GO:0031034 138 0.012
establishment of organelle localization GO:0051656 123 0.011
tube formation GO:0035148 2 0.011
protein complex assembly GO:0006461 186 0.011
peptide hormone secretion GO:0030072 2 0.011
intracellular receptor signaling pathway GO:0030522 2 0.011
macromolecular complex subunit organization GO:0043933 320 0.011
regulation of multi organism process GO:0043900 69 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
positive regulation of molecular function GO:0044093 61 0.011
posttranscriptional gene silencing by rna GO:0035194 143 0.011
hormone secretion GO:0046879 2 0.011
establishment of protein localization to membrane GO:0090150 3 0.011
regulation of signal transduction GO:0009966 135 0.011
adult behavior GO:0030534 3 0.011
regulation of transport GO:0051049 91 0.011
regulation of stem cell differentiation GO:2000736 1 0.010
response to topologically incorrect protein GO:0035966 82 0.010
regulation of molecular function GO:0065009 89 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.010
axis specification GO:0009798 23 0.010
regulation of intracellular signal transduction GO:1902531 77 0.010
dendrite development GO:0016358 42 0.010

C16B8.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.015