Caenorhabditis elegans

90 known processes

let-754 (CELE_C29E4.8)

Protein LET-754

let-754 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.726
receptor mediated endocytosis GO:0006898 715 0.637
embryo development GO:0009790 3052 0.550
vesicle mediated transport GO:0016192 852 0.528
establishment of localization GO:0051234 1171 0.517
sex differentiation GO:0007548 909 0.494
gonad development GO:0008406 840 0.459
endocytosis GO:0006897 819 0.451
post embryonic development GO:0009791 2152 0.369
multicellular organism reproduction GO:0032504 819 0.345
development of primary sexual characteristics GO:0045137 840 0.326
transport GO:0006810 1093 0.305
regulation of developmental process GO:0050793 684 0.255
organ development GO:0048513 1102 0.248
pronuclear migration GO:0035046 51 0.246
organelle organization GO:0006996 783 0.242
death GO:0016265 547 0.229
locomotion GO:0040011 1634 0.227
developmental process involved in reproduction GO:0003006 1165 0.211
sexual reproduction GO:0019953 546 0.208
single organism reproductive process GO:0044702 1196 0.199
single fertilization GO:0007338 61 0.174
determination of adult lifespan GO:0008340 812 0.166
cell migration GO:0016477 306 0.158
cellular localization GO:0051641 360 0.155
regulation of multicellular organism growth GO:0040014 373 0.148
multicellular organismal aging GO:0010259 812 0.148
single organism transport GO:0044765 447 0.147
aging GO:0007568 812 0.145
positive regulation of multicellular organismal process GO:0051240 417 0.136
establishment of organelle localization GO:0051656 123 0.136
developmental growth GO:0048589 412 0.135
reproductive system development GO:0061458 850 0.135
single organism localization GO:1902578 518 0.130
multicellular organismal reproductive process GO:0048609 815 0.124
cell development GO:0048468 696 0.120
establishment of nucleus localization GO:0040023 55 0.116
macromolecule localization GO:0033036 771 0.100
regulation of multicellular organismal process GO:0051239 726 0.096
positive regulation of developmental process GO:0051094 408 0.091
multi organism reproductive process GO:0044703 867 0.091
secretion by cell GO:0032940 138 0.087
apoptotic process GO:0006915 478 0.087
muscle cell differentiation GO:0042692 171 0.086
regulation of biological quality GO:0065008 741 0.085
body morphogenesis GO:0010171 620 0.076
cell death GO:0008219 547 0.076
muscle structure development GO:0061061 191 0.076
purine ribonucleoside metabolic process GO:0046128 92 0.075
reproductive structure development GO:0048608 850 0.074
programmed cell death GO:0012501 500 0.073
secretion GO:0046903 147 0.073
maintenance of location GO:0051235 580 0.071
organelle localization GO:0051640 127 0.068
gamete generation GO:0007276 461 0.067
cell motility GO:0048870 313 0.067
lipid localization GO:0010876 573 0.066
cellular component assembly GO:0022607 293 0.063
lipid storage GO:0019915 565 0.063
regulation of developmental growth GO:0048638 389 0.061
hermaphrodite genitalia development GO:0040035 734 0.058
positive regulation of multicellular organism growth GO:0040018 352 0.057
protein complex subunit organization GO:0071822 280 0.057
multicellular organism growth GO:0035264 385 0.057
regulation of metabolic process GO:0019222 478 0.057
cellular component movement GO:0006928 388 0.056
genitalia development GO:0048806 741 0.056
organic substance catabolic process GO:1901575 294 0.056
positive regulation of developmental growth GO:0048639 354 0.055
molting cycle GO:0042303 281 0.054
muscle cell development GO:0055001 158 0.053
single organism organelle organization GO:1902589 501 0.053
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.053
localization of cell GO:0051674 313 0.053
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.052
single organism signaling GO:0044700 401 0.052
regulation of localization GO:0032879 194 0.052
establishment of localization in cell GO:0051649 318 0.050
protein metabolic process GO:0019538 422 0.049
female gamete generation GO:0007292 254 0.046
behavior GO:0007610 527 0.045
spermatogenesis GO:0007283 41 0.044
nuclear migration GO:0007097 54 0.042
striated muscle cell differentiation GO:0051146 158 0.042
multicellular organismal reproductive behavior GO:0033057 384 0.041
growth GO:0040007 562 0.041
germ cell development GO:0007281 351 0.040
small molecule metabolic process GO:0044281 186 0.040
defense response to bacterium GO:0042742 86 0.040
tissue development GO:0009888 112 0.039
striated muscle cell development GO:0055002 157 0.038
nervous system development GO:0007399 253 0.038
macromolecular complex subunit organization GO:0043933 320 0.037
response to wounding GO:0009611 4 0.037
protein complex assembly GO:0006461 186 0.037
phosphorus metabolic process GO:0006793 232 0.036
purine containing compound metabolic process GO:0072521 95 0.035
innate immune response GO:0045087 190 0.034
cellular component morphogenesis GO:0032989 318 0.034
cellular protein complex assembly GO:0043623 178 0.033
regulation of growth GO:0040008 409 0.033
transmembrane transport GO:0055085 110 0.033
response to chemical GO:0042221 356 0.032
nucleoside phosphate metabolic process GO:0006753 108 0.032
positive regulation of growth GO:0045927 369 0.031
organonitrogen compound metabolic process GO:1901564 151 0.031
regulation of response to stimulus GO:0048583 243 0.030
actin cytoskeleton organization GO:0030036 184 0.030
biosynthetic process GO:0009058 323 0.030
cellular component biogenesis GO:0044085 297 0.030
macromolecular complex assembly GO:0065003 193 0.030
regulation of macromolecule metabolic process GO:0060255 421 0.030
striated muscle myosin thick filament assembly GO:0071688 138 0.029
macromolecule biosynthetic process GO:0009059 250 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
negative regulation of biological process GO:0048519 567 0.029
protein complex biogenesis GO:0070271 186 0.028
nucleoside metabolic process GO:0009116 99 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.027
defense response GO:0006952 296 0.026
carbohydrate derivative metabolic process GO:1901135 141 0.026
muscle tissue development GO:0060537 1 0.026
regulation of gene expression GO:0010468 366 0.026
oxoacid metabolic process GO:0043436 47 0.025
regulation of cell differentiation GO:0045595 81 0.025
oxidative phosphorylation GO:0006119 11 0.025
actomyosin structure organization GO:0031032 154 0.025
cellular macromolecular complex assembly GO:0034622 184 0.024
protein catabolic process GO:0030163 162 0.024
posttranscriptional gene silencing by rna GO:0035194 143 0.024
multi organism reproductive behavior GO:0044705 387 0.024
detection of external stimulus GO:0009581 4 0.023
phosphate containing compound metabolic process GO:0006796 232 0.023
oogenesis GO:0048477 229 0.023
ribonucleoside monophosphate metabolic process GO:0009161 45 0.023
organelle assembly GO:0070925 214 0.022
cellular biosynthetic process GO:0044249 315 0.022
purine ribonucleotide metabolic process GO:0009150 95 0.022
cellular respiration GO:0045333 9 0.021
negative regulation of gene expression GO:0010629 217 0.021
glycosyl compound metabolic process GO:1901657 100 0.021
system process GO:0003008 136 0.021
signal transduction GO:0007165 317 0.020
oxidation reduction process GO:0055114 59 0.020
nucleoside triphosphate metabolic process GO:0009141 87 0.020
response to external stimulus GO:0009605 289 0.020
nucleobase containing compound metabolic process GO:0006139 406 0.020
gene expression GO:0010467 412 0.019
ribonucleoside metabolic process GO:0009119 98 0.019
anatomical structure formation involved in morphogenesis GO:0048646 250 0.019
mitochondrion organization GO:0007005 20 0.019
gene silencing by rna GO:0031047 143 0.019
rna interference GO:0016246 137 0.019
oviposition GO:0018991 364 0.019
phosphorylation GO:0016310 116 0.018
nucleotide metabolic process GO:0009117 108 0.018
digestive system development GO:0055123 122 0.018
cellular protein metabolic process GO:0044267 279 0.018
atp metabolic process GO:0046034 42 0.018
multi multicellular organism process GO:0044706 390 0.018
multi organism behavior GO:0051705 389 0.017
response to external biotic stimulus GO:0043207 101 0.017
myosin filament assembly GO:0031034 138 0.017
fertilization GO:0009566 63 0.017
organic acid metabolic process GO:0006082 47 0.017
negative regulation of macromolecule metabolic process GO:0010605 229 0.017
nucleoside monophosphate metabolic process GO:0009123 46 0.017
myofibril assembly GO:0030239 154 0.017
cytoskeleton organization GO:0007010 339 0.016
catabolic process GO:0009056 318 0.016
ion transport GO:0006811 113 0.016
myosin filament organization GO:0031033 138 0.016
generation of neurons GO:0048699 235 0.016
male gamete generation GO:0048232 41 0.015
purine nucleoside triphosphate metabolic process GO:0009144 87 0.015
regulation of gene expression epigenetic GO:0040029 163 0.015
purine nucleotide metabolic process GO:0006163 95 0.015
digestive tract development GO:0048565 122 0.015
organophosphate metabolic process GO:0019637 125 0.015
reproductive behavior GO:0019098 387 0.014
tube development GO:0035295 126 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
macromolecule catabolic process GO:0009057 202 0.014
carboxylic acid metabolic process GO:0019752 34 0.014
epithelium development GO:0060429 68 0.014
inductive cell migration GO:0040039 145 0.014
eating behavior GO:0042755 59 0.014
negative regulation of developmental process GO:0051093 227 0.014
organ morphogenesis GO:0009887 67 0.014
immune response GO:0006955 192 0.014
ion transmembrane transport GO:0034220 91 0.013
posttranscriptional regulation of gene expression GO:0010608 166 0.013
regulation of cellular metabolic process GO:0031323 305 0.013
regulation of locomotion GO:0040012 161 0.012
nucleus localization GO:0051647 55 0.012
purine nucleoside metabolic process GO:0042278 92 0.012
neurogenesis GO:0022008 236 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
regeneration GO:0031099 4 0.012
actin filament based process GO:0030029 191 0.012
macromolecule modification GO:0043412 218 0.012
regulation of gene silencing GO:0060968 3 0.011
gene silencing GO:0016458 143 0.011
response to abiotic stimulus GO:0009628 152 0.011
signaling GO:0023052 401 0.011
regulation of multicellular organismal development GO:2000026 317 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.011
single organism biosynthetic process GO:0044711 91 0.011
response to other organism GO:0051707 101 0.011
regulation of cell motility GO:2000145 57 0.010
ribonucleoside triphosphate catabolic process GO:0009203 72 0.010

let-754 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.023
disease of metabolism DOID:0014667 0 0.018
disease of anatomical entity DOID:7 0 0.016
Human
organ system cancer DOID:0050686 0 0.011