Caenorhabditis elegans

43 known processes

dpy-8 (CELE_C31H2.2)

Protein DPY-8

dpy-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.605
embryo development ending in birth or egg hatching GO:0009792 2992 0.597
locomotion GO:0040011 1634 0.565
post embryonic development GO:0009791 2152 0.559
organ development GO:0048513 1102 0.361
molting cycle GO:0042303 281 0.354
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.334
single organism reproductive process GO:0044702 1196 0.273
aging GO:0007568 812 0.270
programmed cell death GO:0012501 500 0.254
gonad development GO:0008406 840 0.250
vesicle mediated transport GO:0016192 852 0.232
transport GO:0006810 1093 0.227
death GO:0016265 547 0.222
multicellular organismal reproductive process GO:0048609 815 0.215
determination of adult lifespan GO:0008340 812 0.199
protein catabolic process GO:0030163 162 0.199
protein metabolic process GO:0019538 422 0.185
developmental process involved in reproduction GO:0003006 1165 0.183
multicellular organismal aging GO:0010259 812 0.179
multicellular organism growth GO:0035264 385 0.177
body morphogenesis GO:0010171 620 0.169
hermaphrodite genitalia development GO:0040035 734 0.167
endocytosis GO:0006897 819 0.160
positive regulation of multicellular organismal process GO:0051240 417 0.157
catabolic process GO:0009056 318 0.155
receptor mediated endocytosis GO:0006898 715 0.150
development of primary sexual characteristics GO:0045137 840 0.141
regulation of multicellular organism growth GO:0040014 373 0.140
defense response GO:0006952 296 0.138
response to external stimulus GO:0009605 289 0.133
reproductive behavior GO:0019098 387 0.127
regulation of vulval development GO:0040028 248 0.123
response to other organism GO:0051707 101 0.123
apoptotic process GO:0006915 478 0.119
reproductive system development GO:0061458 850 0.111
establishment of localization GO:0051234 1171 0.110
defense response to other organism GO:0098542 100 0.109
reproductive structure development GO:0048608 850 0.108
regulation of biological quality GO:0065008 741 0.108
response to biotic stimulus GO:0009607 101 0.107
cell development GO:0048468 696 0.107
negative regulation of nematode larval development GO:0061064 208 0.106
response to bacterium GO:0009617 86 0.104
macromolecule catabolic process GO:0009057 202 0.102
vulval development GO:0040025 333 0.100
regulation of developmental process GO:0050793 684 0.095
multi organism reproductive process GO:0044703 867 0.094
macromolecule localization GO:0033036 771 0.090
lipid localization GO:0010876 573 0.089
collagen and cuticulin based cuticle development GO:0040002 99 0.089
defense response to gram negative bacterium GO:0050829 64 0.088
regulation of growth GO:0040008 409 0.085
sex differentiation GO:0007548 909 0.083
cuticle development GO:0042335 100 0.082
genitalia development GO:0048806 741 0.078
positive regulation of multicellular organism growth GO:0040018 352 0.077
multi organism reproductive behavior GO:0044705 387 0.076
regulation of nematode larval development GO:0061062 260 0.075
maintenance of location GO:0051235 580 0.074
regulation of multicellular organismal process GO:0051239 726 0.073
positive regulation of developmental process GO:0051094 408 0.071
lipid storage GO:0019915 565 0.071
single organism organelle organization GO:1902589 501 0.067
growth GO:0040007 562 0.066
post embryonic organ development GO:0048569 336 0.066
positive regulation of growth GO:0045927 369 0.066
cell death GO:0008219 547 0.065
single organism signaling GO:0044700 401 0.064
specification of axis polarity GO:0065001 13 0.064
developmental growth GO:0048589 412 0.063
positive regulation of developmental growth GO:0048639 354 0.063
macromolecular complex subunit organization GO:0043933 320 0.063
organic substance catabolic process GO:1901575 294 0.063
regulation of multicellular organismal development GO:2000026 317 0.060
regulation of post embryonic development GO:0048580 260 0.060
response to external biotic stimulus GO:0043207 101 0.058
sexual reproduction GO:0019953 546 0.057
regulation of developmental growth GO:0048638 389 0.056
germ cell development GO:0007281 351 0.056
striated muscle cell differentiation GO:0051146 158 0.054
regulation of gene expression GO:0010468 366 0.054
regulation of organ morphogenesis GO:2000027 4 0.053
multicellular organism reproduction GO:0032504 819 0.053
organelle organization GO:0006996 783 0.051
negative regulation of biological process GO:0048519 567 0.049
establishment of cell polarity GO:0030010 46 0.049
cell motility GO:0048870 313 0.048
carbohydrate derivative metabolic process GO:1901135 141 0.048
cytoskeleton organization GO:0007010 339 0.046
signaling GO:0023052 401 0.042
gene expression GO:0010467 412 0.042
male sex differentiation GO:0046661 86 0.040
negative regulation of vulval development GO:0040027 206 0.039
localization of cell GO:0051674 313 0.038
defense response to bacterium GO:0042742 86 0.038
organelle fission GO:0048285 363 0.038
multicellular organismal reproductive behavior GO:0033057 384 0.038
sensory organ morphogenesis GO:0090596 2 0.037
oviposition GO:0018991 364 0.037
muscle structure development GO:0061061 191 0.036
cell cycle process GO:0022402 482 0.035
cellular protein metabolic process GO:0044267 279 0.033
inductive cell migration GO:0040039 145 0.032
generation of neurons GO:0048699 235 0.030
membrane organization GO:0061024 135 0.030
meiotic nuclear division GO:0007126 300 0.029
oogenesis GO:0048477 229 0.029
cell migration GO:0016477 306 0.029
cellular protein complex assembly GO:0043623 178 0.029
regulation of macromolecule metabolic process GO:0060255 421 0.029
behavior GO:0007610 527 0.029
negative regulation of post embryonic development GO:0048581 208 0.029
innate immune response GO:0045087 190 0.029
multi organism behavior GO:0051705 389 0.029
multi multicellular organism process GO:0044706 390 0.028
positive regulation of neurogenesis GO:0050769 4 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.028
protein localization GO:0008104 205 0.028
nervous system development GO:0007399 253 0.028
signal transduction GO:0007165 317 0.027
cellular macromolecular complex assembly GO:0034622 184 0.027
protein complex subunit organization GO:0071822 280 0.027
negative regulation of developmental process GO:0051093 227 0.026
response to chemical GO:0042221 356 0.026
enzyme linked receptor protein signaling pathway GO:0007167 50 0.026
cellular catabolic process GO:0044248 199 0.026
muscle tissue development GO:0060537 1 0.026
tissue development GO:0009888 112 0.026
cellular component assembly GO:0022607 293 0.025
regulation of metabolic process GO:0019222 478 0.025
chromosome segregation GO:0007059 180 0.025
striated muscle cell development GO:0055002 157 0.025
cellular component assembly involved in morphogenesis GO:0010927 183 0.024
muscle cell development GO:0055001 158 0.024
muscle cell differentiation GO:0042692 171 0.024
cellular component morphogenesis GO:0032989 318 0.024
cellular response to chemical stimulus GO:0070887 129 0.024
intracellular transport GO:0046907 77 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
cell surface receptor signaling pathway GO:0007166 149 0.024
actin cytoskeleton organization GO:0030036 184 0.023
protein complex biogenesis GO:0070271 186 0.023
negative regulation of macromolecule metabolic process GO:0010605 229 0.023
establishment or maintenance of cell polarity GO:0007163 63 0.023
protein autoprocessing GO:0016540 2 0.022
nucleic acid metabolic process GO:0090304 299 0.022
androgen metabolic process GO:0008209 1 0.022
biosynthetic process GO:0009058 323 0.021
regulation of molecular function GO:0065009 89 0.021
microtubule based process GO:0007017 182 0.021
regulation of lipid biosynthetic process GO:0046890 1 0.021
cellular response to organic substance GO:0071310 119 0.021
regulation of macromolecule biosynthetic process GO:0010556 189 0.021
cellular biosynthetic process GO:0044249 315 0.020
pigmentation GO:0043473 2 0.020
positive regulation of molecular function GO:0044093 61 0.020
immune response GO:0006955 192 0.020
single organism localization GO:1902578 518 0.020
regulation of nucleocytoplasmic transport GO:0046822 3 0.020
regulation of canonical wnt signaling pathway GO:0060828 1 0.019
actin filament based process GO:0030029 191 0.019
posttranscriptional gene silencing GO:0016441 143 0.019
cellular component movement GO:0006928 388 0.019
cellular response to endogenous stimulus GO:0071495 32 0.019
response to wounding GO:0009611 4 0.019
regulation of cell motility GO:2000145 57 0.019
nematode male tail tip morphogenesis GO:0045138 77 0.019
regulation of cytoplasmic transport GO:1903649 3 0.018
canonical wnt signaling pathway GO:0060070 3 0.018
cell cycle GO:0007049 526 0.018
macromolecular complex assembly GO:0065003 193 0.018
meiotic chromosome segregation GO:0045132 139 0.018
cellular protein modification process GO:0006464 207 0.017
positive regulation of macromolecule metabolic process GO:0010604 149 0.017
gamete generation GO:0007276 461 0.017
single organism transport GO:0044765 447 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
regulation of cellular metabolic process GO:0031323 305 0.017
actomyosin structure organization GO:0031032 154 0.017
organelle assembly GO:0070925 214 0.017
positive regulation of intracellular transport GO:0032388 2 0.017
cell proliferation GO:0008283 116 0.017
regulation of bmp signaling pathway GO:0030510 3 0.016
phagocytosis engulfment GO:0006911 98 0.016
steroid biosynthetic process GO:0006694 2 0.016
rna metabolic process GO:0016070 228 0.016
neurogenesis GO:0022008 236 0.016
cellular component biogenesis GO:0044085 297 0.016
system process GO:0003008 136 0.015
protein modification process GO:0036211 207 0.015
intracellular signal transduction GO:0035556 96 0.015
cellular macromolecule biosynthetic process GO:0034645 247 0.015
rna biosynthetic process GO:0032774 169 0.015
female gamete generation GO:0007292 254 0.015
phosphate containing compound metabolic process GO:0006796 232 0.015
cell projection organization GO:0030030 231 0.015
neuron differentiation GO:0030182 217 0.015
skeletal muscle organ development GO:0060538 3 0.015
dna templated transcription elongation GO:0006354 1 0.015
muscle fiber development GO:0048747 2 0.015
epithelial cell proliferation GO:0050673 1 0.014
negative regulation of multicellular organism growth GO:0040015 8 0.014
cellular amino acid metabolic process GO:0006520 15 0.014
response to endogenous stimulus GO:0009719 33 0.014
gene silencing by rna GO:0031047 143 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
cellular protein catabolic process GO:0044257 37 0.014
lipid metabolic process GO:0006629 77 0.014
regulation of cell proliferation GO:0042127 105 0.014
regulation of cell cycle GO:0051726 194 0.014
regulation of lipid metabolic process GO:0019216 4 0.014
epithelium development GO:0060429 68 0.013
meiotic cell cycle GO:0051321 335 0.013
establishment of localization in cell GO:0051649 318 0.013
regulation of lipid transport GO:0032368 4 0.013
cell type specific apoptotic process GO:0097285 4 0.013
regulation of locomotion GO:0040012 161 0.013
meiotic cell cycle process GO:1903046 170 0.013
phagocytosis GO:0006909 115 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
regulation of protein import into nucleus GO:0042306 3 0.013
macromolecule modification GO:0043412 218 0.013
regulation of cellular catabolic process GO:0031329 51 0.012
negative regulation of metabolic process GO:0009892 240 0.012
regulation of protein targeting GO:1903533 3 0.012
nucleobase containing compound metabolic process GO:0006139 406 0.012
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.012
regulation of protein localization GO:0032880 50 0.012
regulation of programmed cell death GO:0043067 50 0.012
cell fate commitment GO:0045165 139 0.012
neuron projection morphogenesis GO:0048812 114 0.012
myosin filament organization GO:0031033 138 0.012
digestive tract development GO:0048565 122 0.012
development of primary male sexual characteristics GO:0046546 4 0.012
male anatomical structure morphogenesis GO:0090598 78 0.011
myosin filament assembly GO:0031034 138 0.011
axon development GO:0061564 163 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 1 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.011
neuron development GO:0048666 199 0.011
regulation of primary metabolic process GO:0080090 292 0.011
rna interference GO:0016246 137 0.011
response to organic substance GO:0010033 131 0.010
oxidative phosphorylation GO:0006119 11 0.010
polarity specification of anterior posterior axis GO:0009949 8 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
single organism intracellular transport GO:1902582 70 0.010
negative regulation of cellular process GO:0048523 239 0.010
bmp signaling pathway GO:0030509 3 0.010
single organism biosynthetic process GO:0044711 91 0.010
male gonad development GO:0008584 4 0.010
regulation of rna metabolic process GO:0051252 173 0.010

dpy-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014