Caenorhabditis elegans

23 known processes

vps-33.2 (CELE_C56C10.1)

Protein VPS-33.2

vps-33.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.800
post embryonic development GO:0009791 2152 0.702
aging GO:0007568 812 0.579
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.569
establishment of localization GO:0051234 1171 0.550
locomotion GO:0040011 1634 0.537
developmental process involved in reproduction GO:0003006 1165 0.516
reproductive system development GO:0061458 850 0.505
gamete generation GO:0007276 461 0.481
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.471
receptor mediated endocytosis GO:0006898 715 0.407
genitalia development GO:0048806 741 0.400
regulation of meiotic cell cycle GO:0051445 136 0.376
endocytosis GO:0006897 819 0.371
organ development GO:0048513 1102 0.364
multicellular organism reproduction GO:0032504 819 0.363
cell migration GO:0016477 306 0.350
sexual reproduction GO:0019953 546 0.335
development of primary sexual characteristics GO:0045137 840 0.334
multicellular organismal reproductive process GO:0048609 815 0.330
multicellular organismal aging GO:0010259 812 0.322
Worm
signaling GO:0023052 401 0.318
organelle organization GO:0006996 783 0.314
meiotic nuclear division GO:0007126 300 0.304
reproductive structure development GO:0048608 850 0.296
vesicle mediated transport GO:0016192 852 0.272
meiotic cell cycle GO:0051321 335 0.272
hermaphrodite genitalia development GO:0040035 734 0.263
transport GO:0006810 1093 0.257
germ cell development GO:0007281 351 0.254
sex differentiation GO:0007548 909 0.253
single organism reproductive process GO:0044702 1196 0.253
female gamete generation GO:0007292 254 0.249
negative regulation of metabolic process GO:0009892 240 0.230
regulation of developmental process GO:0050793 684 0.230
positive regulation of metabolic process GO:0009893 187 0.223
determination of adult lifespan GO:0008340 812 0.210
Worm
gonad development GO:0008406 840 0.208
multicellular organismal reproductive behavior GO:0033057 384 0.206
body morphogenesis GO:0010171 620 0.204
organelle fission GO:0048285 363 0.196
behavior GO:0007610 527 0.187
vulval development GO:0040025 333 0.185
oviposition GO:0018991 364 0.177
multi organism reproductive process GO:0044703 867 0.171
regulation of rna metabolic process GO:0051252 173 0.171
cellular catabolic process GO:0044248 199 0.171
cell motility GO:0048870 313 0.171
regulation of multicellular organismal development GO:2000026 317 0.167
cellular localization GO:0051641 360 0.167
head development GO:0060322 1 0.166
localization of cell GO:0051674 313 0.166
negative regulation of vulval development GO:0040027 206 0.165
regulation of gene expression GO:0010468 366 0.162
cellular protein metabolic process GO:0044267 279 0.156
protein catabolic process GO:0030163 162 0.154
regulation of cellular metabolic process GO:0031323 305 0.146
regulation of multicellular organismal process GO:0051239 726 0.143
meiotic chromosome segregation GO:0045132 139 0.136
chromosome segregation GO:0007059 180 0.133
multi organism behavior GO:0051705 389 0.132
negative regulation of biological process GO:0048519 567 0.128
nucleic acid metabolic process GO:0090304 299 0.126
catabolic process GO:0009056 318 0.121
macromolecule catabolic process GO:0009057 202 0.119
multi organism reproductive behavior GO:0044705 387 0.116
regulation of meiosis GO:0040020 94 0.114
oogenesis GO:0048477 229 0.114
regulation of biological quality GO:0065008 741 0.113
regulation of metabolic process GO:0019222 478 0.112
organic substance catabolic process GO:1901575 294 0.110
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.108
meiotic cell cycle process GO:1903046 170 0.106
post embryonic organ development GO:0048569 336 0.102
cell death GO:0008219 547 0.102
reproductive behavior GO:0019098 387 0.096
programmed cell death GO:0012501 500 0.096
negative regulation of biosynthetic process GO:0009890 65 0.095
pronuclear migration GO:0035046 51 0.093
macromolecule localization GO:0033036 771 0.093
positive regulation of rna metabolic process GO:0051254 103 0.091
single organism signaling GO:0044700 401 0.085
macromolecule modification GO:0043412 218 0.084
positive regulation of cellular process GO:0048522 332 0.084
regulation of locomotion GO:0040012 161 0.084
cellular protein modification process GO:0006464 207 0.083
regulation of primary metabolic process GO:0080090 292 0.083
gene expression GO:0010467 412 0.082
regulation of vulval development GO:0040028 248 0.081
regulation of cell division GO:0051302 142 0.080
negative regulation of gene expression GO:0010629 217 0.080
single organism organelle organization GO:1902589 501 0.079
cell proliferation GO:0008283 116 0.079
cell cycle GO:0007049 526 0.078
tube development GO:0035295 126 0.077
growth GO:0040007 562 0.076
transcription from rna polymerase ii promoter GO:0006366 149 0.076
regulation of cellular component organization GO:0051128 248 0.075
rna metabolic process GO:0016070 228 0.075
regulation of cell communication GO:0010646 176 0.075
apoptotic process GO:0006915 478 0.074
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.074
regulation of response to stimulus GO:0048583 243 0.073
protein localization GO:0008104 205 0.073
positive regulation of cellular metabolic process GO:0031325 178 0.073
cellular component biogenesis GO:0044085 297 0.071
response to chemical GO:0042221 356 0.071
nervous system development GO:0007399 253 0.069
negative regulation of cellular protein metabolic process GO:0032269 27 0.068
multi multicellular organism process GO:0044706 390 0.068
regulation of growth GO:0040008 409 0.068
protein metabolic process GO:0019538 422 0.067
regulation of transcription dna templated GO:0006355 164 0.067
cell fate commitment GO:0045165 139 0.066
negative regulation of cellular process GO:0048523 239 0.066
regulation of chromosome organization GO:0033044 20 0.065
negative regulation of cell cycle GO:0045786 53 0.063
maintenance of location GO:0051235 580 0.062
regulation of organelle organization GO:0033043 164 0.062
chromosome organization GO:0051276 104 0.061
single organism transport GO:0044765 447 0.061
negative regulation of multicellular organismal process GO:0051241 236 0.060
regulation of multicellular organism growth GO:0040014 373 0.059
regulation of cell motility GO:2000145 57 0.059
small gtpase mediated signal transduction GO:0007264 32 0.058
oxoacid metabolic process GO:0043436 47 0.057
protein modification process GO:0036211 207 0.056
lipid storage GO:0019915 565 0.056
cell development GO:0048468 696 0.055
wnt signaling pathway GO:0016055 27 0.055
regulation of cell cycle GO:0051726 194 0.054
posttranscriptional gene silencing GO:0016441 143 0.052
cellular component movement GO:0006928 388 0.052
regulation of macromolecule metabolic process GO:0060255 421 0.052
lipid localization GO:0010876 573 0.052
cell division GO:0051301 262 0.051
signal transduction GO:0007165 317 0.051
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.051
single organism cellular localization GO:1902580 72 0.050
oocyte development GO:0048599 44 0.050
neurogenesis GO:0022008 236 0.050
negative regulation of cellular biosynthetic process GO:0031327 65 0.050
regulation of nematode larval development GO:0061062 260 0.050
organic acid metabolic process GO:0006082 47 0.049
regulation of catalytic activity GO:0050790 78 0.049
neuron differentiation GO:0030182 217 0.049
fertilization GO:0009566 63 0.049
anatomical structure formation involved in morphogenesis GO:0048646 250 0.048
negative regulation of developmental process GO:0051093 227 0.047
molting cycle GO:0042303 281 0.047
posttranscriptional gene silencing by rna GO:0035194 143 0.045
digestive tract morphogenesis GO:0048546 76 0.045
single organism localization GO:1902578 518 0.044
positive regulation of chromosome segregation GO:0051984 1 0.044
nematode male tail tip morphogenesis GO:0045138 77 0.044
regulation of macromolecule biosynthetic process GO:0010556 189 0.044
regulation of protein metabolic process GO:0051246 81 0.044
regulation of cell migration GO:0030334 55 0.044
negative regulation of mitotic cell cycle GO:0045930 42 0.043
positive regulation of multicellular organism growth GO:0040018 352 0.043
regulation of developmental growth GO:0048638 389 0.042
generation of neurons GO:0048699 235 0.041
regulation of cell cycle process GO:0010564 145 0.041
phosphorus metabolic process GO:0006793 232 0.041
macromolecule biosynthetic process GO:0009059 250 0.041
cell morphogenesis GO:0000902 163 0.040
carboxylic acid metabolic process GO:0019752 34 0.040
death GO:0016265 547 0.039
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.039
regulation of cellular biosynthetic process GO:0031326 189 0.039
oocyte differentiation GO:0009994 45 0.039
negative regulation of nematode larval development GO:0061064 208 0.039
organic substance biosynthetic process GO:1901576 323 0.039
negative regulation of macromolecule metabolic process GO:0010605 229 0.038
cellular component morphogenesis GO:0032989 318 0.038
meiosis i GO:0007127 19 0.038
positive regulation of growth GO:0045927 369 0.037
phosphorylation GO:0016310 116 0.037
positive regulation of nucleic acid templated transcription GO:1903508 102 0.037
digestive tract development GO:0048565 122 0.037
regulation of nitrogen compound metabolic process GO:0051171 222 0.036
inductive cell migration GO:0040039 145 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.036
posttranscriptional regulation of gene expression GO:0010608 166 0.036
cell morphogenesis involved in differentiation GO:0000904 112 0.036
gastrulation GO:0007369 58 0.036
cellular biosynthetic process GO:0044249 315 0.034
regulation of phosphorus metabolic process GO:0051174 81 0.034
positive regulation of macromolecule metabolic process GO:0010604 149 0.034
positive regulation of developmental growth GO:0048639 354 0.034
cell cell signaling GO:0007267 118 0.033
regulation of catabolic process GO:0009894 57 0.033
regulation of localization GO:0032879 194 0.033
positive regulation of developmental process GO:0051094 408 0.032
cell cycle process GO:0022402 482 0.032
positive regulation of neurogenesis GO:0050769 4 0.032
small molecule metabolic process GO:0044281 186 0.032
positive regulation of molecular function GO:0044093 61 0.032
cytoskeleton organization GO:0007010 339 0.032
digestive system development GO:0055123 122 0.032
regulation of cellular component movement GO:0051270 62 0.031
cellular component assembly GO:0022607 293 0.031
dauer larval development GO:0040024 92 0.031
neuron projection morphogenesis GO:0048812 114 0.030
regulation of organ morphogenesis GO:2000027 4 0.030
regulation of cell proliferation GO:0042127 105 0.030
developmental growth GO:0048589 412 0.030
neuron development GO:0048666 199 0.030
phosphate containing compound metabolic process GO:0006796 232 0.030
regulation of biosynthetic process GO:0009889 189 0.030
cellular protein catabolic process GO:0044257 37 0.030
single organism catabolic process GO:0044712 129 0.029
epithelium development GO:0060429 68 0.029
regulation of rna biosynthetic process GO:2001141 165 0.029
cell surface receptor signaling pathway GO:0007166 149 0.029
cell projection morphogenesis GO:0048858 148 0.029
regulation of molecular function GO:0065009 89 0.029
cellular response to dna damage stimulus GO:0006974 41 0.029
positive regulation of phosphorus metabolic process GO:0010562 56 0.029
cellular amino acid metabolic process GO:0006520 15 0.029
cellular macromolecule biosynthetic process GO:0034645 247 0.028
positive regulation of phosphate metabolic process GO:0045937 56 0.028
regulation of cellular catabolic process GO:0031329 51 0.028
regulation of mesoderm development GO:2000380 2 0.028
tube morphogenesis GO:0035239 79 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.028
spermatogenesis GO:0007283 41 0.027
multicellular organism growth GO:0035264 385 0.027
nucleobase containing compound metabolic process GO:0006139 406 0.027
establishment of localization in cell GO:0051649 318 0.026
positive regulation of multicellular organismal process GO:0051240 417 0.026
membrane organization GO:0061024 135 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.026
positive regulation of chromosome organization GO:2001252 2 0.026
regulation of gene expression epigenetic GO:0040029 163 0.026
ras protein signal transduction GO:0007265 31 0.025
dna metabolic process GO:0006259 74 0.025
organelle assembly GO:0070925 214 0.025
regulation of mitotic cell cycle GO:0007346 76 0.025
regulation of signaling GO:0023051 172 0.024
positive regulation of rna biosynthetic process GO:1902680 102 0.024
gtp metabolic process GO:0046039 46 0.024
response to wounding GO:0009611 4 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.024
regulation of protein localization GO:0032880 50 0.024
organic cyclic compound catabolic process GO:1901361 119 0.023
biosynthetic process GO:0009058 323 0.023
regulation of signal transduction GO:0009966 135 0.023
long term memory GO:0007616 2 0.023
cellular macromolecule catabolic process GO:0044265 73 0.022
cellular protein localization GO:0034613 75 0.022
phagocytosis engulfment GO:0006911 98 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.022
regulation of phosphate metabolic process GO:0019220 81 0.022
organ morphogenesis GO:0009887 67 0.022
single fertilization GO:0007338 61 0.022
regulation of gtp catabolic process GO:0033124 32 0.021
membrane invagination GO:0010324 98 0.021
protein complex assembly GO:0006461 186 0.021
regulation of post embryonic development GO:0048580 260 0.021
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.021
positive regulation of catabolic process GO:0009896 38 0.021
cell cycle switching mitotic to meiotic cell cycle GO:0051728 35 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.020
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.020
positive regulation of catalytic activity GO:0043085 59 0.020
gene silencing by rna GO:0031047 143 0.020
polar body extrusion after meiotic divisions GO:0040038 14 0.020
cellular response to stress GO:0033554 162 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
single organism behavior GO:0044708 83 0.020
mating behavior GO:0007617 32 0.020
regulation of nuclear division GO:0051783 115 0.019
learning or memory GO:0007611 27 0.019
defense response GO:0006952 296 0.019
positive regulation of protein modification process GO:0031401 29 0.019
axonogenesis GO:0007409 102 0.019
embryonic morphogenesis GO:0048598 152 0.019
nuclear migration GO:0007097 54 0.019
regulation of cellular protein metabolic process GO:0032268 75 0.019
system process GO:0003008 136 0.018
phagocytosis GO:0006909 115 0.018
cellular amine metabolic process GO:0044106 15 0.018
positive regulation of cellular component organization GO:0051130 34 0.018
positive regulation of phosphorylation GO:0042327 27 0.018
response to endogenous stimulus GO:0009719 33 0.018
response to organic substance GO:0010033 131 0.018
nucleoside catabolic process GO:0009164 78 0.018
cognition GO:0050890 27 0.018
cell projection organization GO:0030030 231 0.018
regulation of chromosome segregation GO:0051983 20 0.018
histone modification GO:0016570 30 0.018
cellular response to organic substance GO:0071310 119 0.018
positive regulation of meiotic cell cycle GO:0051446 47 0.018
male anatomical structure morphogenesis GO:0090598 78 0.017
gene silencing GO:0016458 143 0.017
regulation of phosphorylation GO:0042325 45 0.017
positive regulation of cell communication GO:0010647 69 0.017
modification dependent macromolecule catabolic process GO:0043632 32 0.017
organophosphate metabolic process GO:0019637 125 0.017
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
cell part morphogenesis GO:0032990 152 0.017
regulation of transferase activity GO:0051338 31 0.017
memory GO:0007613 3 0.017
negative regulation of nucleic acid templated transcription GO:1903507 53 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
regulation of protein import into nucleus GO:0042306 3 0.017
actin filament based process GO:0030029 191 0.016
establishment of nucleus localization GO:0040023 55 0.016
amine metabolic process GO:0009308 15 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
secretion GO:0046903 147 0.016
gtp catabolic process GO:0006184 46 0.016
proteolysis GO:0006508 61 0.016
regulation of mitotic sister chromatid segregation GO:0033047 16 0.016
positive regulation of cell cycle GO:0045787 55 0.015
cellular ketone metabolic process GO:0042180 14 0.015
regeneration GO:0031099 4 0.015
guanosine containing compound catabolic process GO:1901069 48 0.015
cellular macromolecule localization GO:0070727 75 0.015
cyclin catabolic process GO:0008054 3 0.015
skeletal muscle organ development GO:0060538 3 0.015
apoptotic cell clearance GO:0043277 111 0.015
response to external stimulus GO:0009605 289 0.015
positive regulation of transcription dna templated GO:0045893 102 0.015
organelle localization GO:0051640 127 0.015
axon development GO:0061564 163 0.015
hermaphrodite germ line sex determination GO:0040021 48 0.015
organophosphate catabolic process GO:0046434 81 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.014
metaphase anaphase transition of mitotic cell cycle GO:0007091 10 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
aromatic compound catabolic process GO:0019439 116 0.014
regulation of nucleocytoplasmic transport GO:0046822 3 0.014
actin cytoskeleton organization GO:0030036 184 0.014
intracellular signal transduction GO:0035556 96 0.014
regulation of nucleic acid templated transcription GO:1903506 165 0.014
ubiquitin dependent protein catabolic process GO:0006511 32 0.014
macromolecular complex subunit organization GO:0043933 320 0.014
sensory organ morphogenesis GO:0090596 2 0.014
signal transduction by phosphorylation GO:0023014 31 0.014
neuron projection development GO:0031175 187 0.013
regulation of protein modification process GO:0031399 46 0.013
negative regulation of cell communication GO:0010648 61 0.013
sex determination GO:0007530 60 0.013
canonical wnt signaling pathway GO:0060070 3 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
negative regulation of post embryonic development GO:0048581 208 0.013
rna biosynthetic process GO:0032774 169 0.013
purine ribonucleotide catabolic process GO:0009154 75 0.013
rho protein signal transduction GO:0007266 2 0.013
response to external biotic stimulus GO:0043207 101 0.013
male sex differentiation GO:0046661 86 0.013
response to abiotic stimulus GO:0009628 152 0.013
protein complex biogenesis GO:0070271 186 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.012
cellular response to endogenous stimulus GO:0071495 32 0.012
regulation of cell differentiation GO:0045595 81 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.012
cuticle development GO:0042335 100 0.012
cellular macromolecular complex assembly GO:0034622 184 0.012
cellular protein complex assembly GO:0043623 178 0.012
covalent chromatin modification GO:0016569 30 0.012
protein complex subunit organization GO:0071822 280 0.012
positive regulation of cellular catabolic process GO:0031331 35 0.012
regulation of protein targeting GO:1903533 3 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.012
regulation of protein stability GO:0031647 3 0.012
protein localization to organelle GO:0033365 37 0.011
pattern specification process GO:0007389 59 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
ion transport GO:0006811 113 0.011
negative regulation of signal transduction GO:0009968 60 0.011
positive regulation of protein metabolic process GO:0051247 45 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
protein modification by small protein conjugation or removal GO:0070647 40 0.011
heterocycle catabolic process GO:0046700 119 0.011
homeostatic process GO:0042592 51 0.011
metaphase anaphase transition of cell cycle GO:0044784 15 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
regulation of neurogenesis GO:0050767 40 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
guanosine containing compound metabolic process GO:1901068 49 0.011
intracellular receptor signaling pathway GO:0030522 2 0.011
muscle structure development GO:0061061 191 0.011
synaptic transmission GO:0007268 106 0.011
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
regulation of ras protein signal transduction GO:0046578 41 0.011
nucleus localization GO:0051647 55 0.011
regulation of protein catabolic process GO:0042176 13 0.011
nucleotide catabolic process GO:0009166 77 0.011
dna templated transcription elongation GO:0006354 1 0.011
regulation of chromatin modification GO:1903308 2 0.011
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
regulation of small gtpase mediated signal transduction GO:0051056 41 0.010
mitotic g2 m transition checkpoint GO:0044818 1 0.010
positive regulation of nucleoside metabolic process GO:0045979 28 0.010
protein phosphorylation GO:0006468 85 0.010
dendrite development GO:0016358 42 0.010
regulation of multi organism process GO:0043900 69 0.010
muscle cell development GO:0055001 158 0.010
rna interference GO:0016246 137 0.010
carbohydrate derivative catabolic process GO:1901136 82 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010

vps-33.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.011
disease of anatomical entity DOID:7 0 0.011
organ system cancer DOID:0050686 0 0.010