Caenorhabditis elegans

13 known processes

aka-1 (CELE_D1022.7)

Protein AKA-1

aka-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic cell cycle process GO:1903047 194 0.430
embryo development GO:0009790 3052 0.423
reproductive system development GO:0061458 850 0.381
embryo development ending in birth or egg hatching GO:0009792 2992 0.364
cell cycle process GO:0022402 482 0.281
multicellular organismal reproductive process GO:0048609 815 0.268
multicellular organismal reproductive behavior GO:0033057 384 0.259
cell cycle GO:0007049 526 0.230
signal transduction GO:0007165 317 0.229
Human Fly
death GO:0016265 547 0.197
developmental process involved in reproduction GO:0003006 1165 0.192
gonad development GO:0008406 840 0.185
oviposition GO:0018991 364 0.181
organelle organization GO:0006996 783 0.180
apoptotic process GO:0006915 478 0.170
multicellular organism reproduction GO:0032504 819 0.170
macromolecule biosynthetic process GO:0009059 250 0.156
reproductive structure development GO:0048608 850 0.155
single organism reproductive process GO:0044702 1196 0.147
multi organism reproductive process GO:0044703 867 0.141
regulation of response to stimulus GO:0048583 243 0.135
Fly
positive regulation of cellular process GO:0048522 332 0.130
locomotion GO:0040011 1634 0.129
development of primary sexual characteristics GO:0045137 840 0.129
oogenesis GO:0048477 229 0.127
vesicle mediated transport GO:0016192 852 0.127
sex differentiation GO:0007548 909 0.121
regulation of biological quality GO:0065008 741 0.121
Fly
organ development GO:0048513 1102 0.119
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.117
cell development GO:0048468 696 0.109
gene expression GO:0010467 412 0.108
behavior GO:0007610 527 0.107
aging GO:0007568 812 0.106
neurogenesis GO:0022008 236 0.102
signaling GO:0023052 401 0.101
Human Fly
transport GO:0006810 1093 0.100
Human
organic substance biosynthetic process GO:1901576 323 0.099
multi organism reproductive behavior GO:0044705 387 0.098
sexual reproduction GO:0019953 546 0.097
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.095
single organism transport GO:0044765 447 0.093
Human
cell death GO:0008219 547 0.091
positive regulation of cellular metabolic process GO:0031325 178 0.090
programmed cell death GO:0012501 500 0.090
regulation of developmental process GO:0050793 684 0.086
determination of adult lifespan GO:0008340 812 0.086
single organism organelle organization GO:1902589 501 0.086
growth GO:0040007 562 0.085
taxis GO:0042330 128 0.084
reproductive behavior GO:0019098 387 0.083
maintenance of location GO:0051235 580 0.081
germ cell development GO:0007281 351 0.081
regulation of mitotic cell cycle GO:0007346 76 0.080
regulation of growth GO:0040008 409 0.079
digestive tract morphogenesis GO:0048546 76 0.079
intracellular signal transduction GO:0035556 96 0.078
regulation of cell communication GO:0010646 176 0.077
Fly
lipid localization GO:0010876 573 0.076
macromolecule localization GO:0033036 771 0.075
Human
cytokinesis GO:0000910 80 0.075
multi multicellular organism process GO:0044706 390 0.074
chromosome segregation GO:0007059 180 0.074
post embryonic development GO:0009791 2152 0.073
regulation of multicellular organismal process GO:0051239 726 0.073
female gamete generation GO:0007292 254 0.073
regulation of primary metabolic process GO:0080090 292 0.072
receptor mediated endocytosis GO:0006898 715 0.071
lipid storage GO:0019915 565 0.070
endocytosis GO:0006897 819 0.070
gamete generation GO:0007276 461 0.069
hermaphrodite genitalia development GO:0040035 734 0.069
multi organism behavior GO:0051705 389 0.066
dna metabolic process GO:0006259 74 0.064
cellular catabolic process GO:0044248 199 0.059
ras protein signal transduction GO:0007265 31 0.056
developmental growth GO:0048589 412 0.055
response to chemical GO:0042221 356 0.054
Human
cellular biosynthetic process GO:0044249 315 0.053
body morphogenesis GO:0010171 620 0.053
regulation of cellular metabolic process GO:0031323 305 0.052
regulation of macromolecule biosynthetic process GO:0010556 189 0.049
organelle fission GO:0048285 363 0.049
nucleobase containing compound metabolic process GO:0006139 406 0.049
genitalia development GO:0048806 741 0.049
single organism signaling GO:0044700 401 0.047
Human Fly
multicellular organism growth GO:0035264 385 0.047
regulation of rna biosynthetic process GO:2001141 165 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
chromosome organization GO:0051276 104 0.045
negative regulation of biological process GO:0048519 567 0.045
cellular localization GO:0051641 360 0.044
Human
macromolecular complex assembly GO:0065003 193 0.044
Human
regulation of cell cycle process GO:0010564 145 0.043
regulation of macromolecule metabolic process GO:0060255 421 0.042
chemotaxis GO:0006935 120 0.042
regulation of ras protein signal transduction GO:0046578 41 0.041
positive regulation of macromolecule metabolic process GO:0010604 149 0.040
axonogenesis GO:0007409 102 0.040
cell division GO:0051301 262 0.040
Fly
macromolecule catabolic process GO:0009057 202 0.040
regulation of vulval development GO:0040028 248 0.040
meiotic cell cycle process GO:1903046 170 0.039
cellular component biogenesis GO:0044085 297 0.039
Human
regulation of gene expression GO:0010468 366 0.038
cytoskeleton organization GO:0007010 339 0.038
purine nucleoside triphosphate catabolic process GO:0009146 72 0.036
negative regulation of nematode larval development GO:0061064 208 0.036
biosynthetic process GO:0009058 323 0.035
regulation of cell cycle GO:0051726 194 0.035
cell part morphogenesis GO:0032990 152 0.035
vulval development GO:0040025 333 0.035
phosphorus metabolic process GO:0006793 232 0.035
regulation of multicellular organism growth GO:0040014 373 0.033
regulation of metabolic process GO:0019222 478 0.033
nucleic acid metabolic process GO:0090304 299 0.032
regulation of rna metabolic process GO:0051252 173 0.032
neuron projection development GO:0031175 187 0.031
nucleotide metabolic process GO:0009117 108 0.031
protein complex biogenesis GO:0070271 186 0.031
Human
muscle cell differentiation GO:0042692 171 0.031
protein complex assembly GO:0006461 186 0.030
Human
organic substance catabolic process GO:1901575 294 0.030
mitotic nuclear division GO:0007067 89 0.030
response to abiotic stimulus GO:0009628 152 0.029
small gtpase mediated signal transduction GO:0007264 32 0.029
multicellular organismal aging GO:0010259 812 0.029
catabolic process GO:0009056 318 0.029
nucleic acid templated transcription GO:0097659 169 0.029
macromolecular complex subunit organization GO:0043933 320 0.029
Human
positive regulation of epithelial cell proliferation GO:0050679 1 0.028
response to organic substance GO:0010033 131 0.028
Human
negative regulation of gene expression GO:0010629 217 0.027
positive regulation of cell projection organization GO:0031346 4 0.027
cell projection organization GO:0030030 231 0.027
regulation of biosynthetic process GO:0009889 189 0.027
protein catabolic process GO:0030163 162 0.027
cellular nitrogen compound catabolic process GO:0044270 119 0.027
positive regulation of phosphate metabolic process GO:0045937 56 0.027
negative regulation of developmental process GO:0051093 227 0.026
regulation of post embryonic development GO:0048580 260 0.026
phosphate containing compound metabolic process GO:0006796 232 0.026
cellular protein complex localization GO:0034629 3 0.025
response to wounding GO:0009611 4 0.025
generation of neurons GO:0048699 235 0.025
positive regulation of metabolic process GO:0009893 187 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
regulation of cell division GO:0051302 142 0.025
negative regulation of multicellular organismal process GO:0051241 236 0.025
regulation of organ morphogenesis GO:2000027 4 0.025
nervous system development GO:0007399 253 0.025
regulation of gene expression epigenetic GO:0040029 163 0.024
protein oligomerization GO:0051259 4 0.023
cellular protein modification process GO:0006464 207 0.023
dna duplex unwinding GO:0032508 3 0.023
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.023
membrane invagination GO:0010324 98 0.022
rna biosynthetic process GO:0032774 169 0.022
rna interference GO:0016246 137 0.022
cellular response to stress GO:0033554 162 0.022
cellular response to dna damage stimulus GO:0006974 41 0.022
head development GO:0060322 1 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.021
regulation of protein metabolic process GO:0051246 81 0.021
cellular component movement GO:0006928 388 0.021
homeostatic process GO:0042592 51 0.021
Fly
purine nucleotide catabolic process GO:0006195 75 0.021
single organism localization GO:1902578 518 0.021
Human
tissue development GO:0009888 112 0.020
localization of cell GO:0051674 313 0.020
negative regulation of metabolic process GO:0009892 240 0.020
regulation of signal transduction GO:0009966 135 0.020
Fly
regulation of nematode larval development GO:0061062 260 0.020
regeneration GO:0031099 4 0.019
regulation of nitrogen compound metabolic process GO:0051171 222 0.019
negative regulation of vulval development GO:0040027 206 0.019
microtubule based process GO:0007017 182 0.019
positive regulation of developmental process GO:0051094 408 0.019
neuron projection guidance GO:0097485 82 0.019
positive regulation of multicellular organism growth GO:0040018 352 0.018
regulation of multicellular organismal development GO:2000026 317 0.018
tube development GO:0035295 126 0.018
positive regulation of growth GO:0045927 369 0.018
regulation of transcription dna templated GO:0006355 164 0.018
negative regulation of cellular process GO:0048523 239 0.018
gastrulation GO:0007369 58 0.018
phagocytosis GO:0006909 115 0.018
cell migration GO:0016477 306 0.017
posttranscriptional gene silencing by rna GO:0035194 143 0.017
neuron differentiation GO:0030182 217 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
ribonucleoside catabolic process GO:0042454 77 0.017
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
cellular protein metabolic process GO:0044267 279 0.017
muscle structure development GO:0061061 191 0.017
regulation of nucleic acid templated transcription GO:1903506 165 0.017
tube morphogenesis GO:0035239 79 0.016
nucleobase containing compound catabolic process GO:0034655 114 0.016
cell proliferation GO:0008283 116 0.016
response to oxygen containing compound GO:1901700 44 0.016
gene silencing GO:0016458 143 0.016
meiotic chromosome segregation GO:0045132 139 0.016
establishment of localization in cell GO:0051649 318 0.016
Human
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.016
positive regulation of multicellular organismal process GO:0051240 417 0.016
establishment of organelle localization GO:0051656 123 0.016
regulation of small gtpase mediated signal transduction GO:0051056 41 0.015
oocyte differentiation GO:0009994 45 0.015
digestive system development GO:0055123 122 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
spindle organization GO:0007051 92 0.015
regulation of developmental growth GO:0048638 389 0.015
carbohydrate derivative catabolic process GO:1901136 82 0.015
response to external stimulus GO:0009605 289 0.015
cell morphogenesis involved in differentiation GO:0000904 112 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.015
negative regulation of macromolecule metabolic process GO:0010605 229 0.015
gene silencing by rna GO:0031047 143 0.015
glycosyl compound metabolic process GO:1901657 100 0.015
digestive tract development GO:0048565 122 0.014
positive regulation of cell migration GO:0030335 3 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
dna geometric change GO:0032392 3 0.014
nucleoside phosphate catabolic process GO:1901292 77 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
cellular response to organic substance GO:0071310 119 0.014
Human
epithelial cell proliferation GO:0050673 1 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
Human
post embryonic organ development GO:0048569 336 0.014
regulation of locomotion GO:0040012 161 0.014
cell morphogenesis GO:0000902 163 0.014
nucleoside phosphate metabolic process GO:0006753 108 0.013
protein localization GO:0008104 205 0.013
Human
muscle tissue development GO:0060537 1 0.013
organelle assembly GO:0070925 214 0.013
purine ribonucleoside catabolic process GO:0046130 75 0.013
establishment of localization GO:0051234 1171 0.013
Human
cellular component morphogenesis GO:0032989 318 0.013
regulation of behavior GO:0050795 97 0.013
organonitrogen compound catabolic process GO:1901565 90 0.013
protein complex subunit organization GO:0071822 280 0.013
Human
regulation of cellular biosynthetic process GO:0031326 189 0.013
cell type specific apoptotic process GO:0097285 4 0.013
system process GO:0003008 136 0.013
small molecule metabolic process GO:0044281 186 0.013
ribose phosphate metabolic process GO:0019693 99 0.013
establishment or maintenance of cell polarity GO:0007163 63 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
heterocycle catabolic process GO:0046700 119 0.013
positive regulation of rna metabolic process GO:0051254 103 0.013
sister chromatid segregation GO:0000819 46 0.013
base excision repair GO:0006284 4 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
negative regulation of cell cycle g2 m phase transition GO:1902750 1 0.013
axon guidance GO:0007411 82 0.012
myosin filament organization GO:0031033 138 0.012
positive regulation of biosynthetic process GO:0009891 109 0.012
protein metabolic process GO:0019538 422 0.012
organ morphogenesis GO:0009887 67 0.012
cellular protein localization GO:0034613 75 0.012
Human
actin filament based process GO:0030029 191 0.012
positive regulation of developmental growth GO:0048639 354 0.012
response to inorganic substance GO:0010035 50 0.012
heterocycle biosynthetic process GO:0018130 187 0.012
myofibril assembly GO:0030239 154 0.012
positive regulation of gene expression GO:0010628 112 0.012
regulation of cell migration GO:0030334 55 0.011
nucleoside catabolic process GO:0009164 78 0.011
transcription dna templated GO:0006351 168 0.011
cellular ketone metabolic process GO:0042180 14 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
ribonucleotide catabolic process GO:0009261 75 0.011
organic substance transport GO:0071702 113 0.011
Human
single organism biosynthetic process GO:0044711 91 0.011
regulation of intracellular signal transduction GO:1902531 77 0.011
mitotic spindle organization GO:0007052 81 0.011
negative regulation of post embryonic development GO:0048581 208 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
meiotic cell cycle GO:0051321 335 0.011
regulation of localization GO:0032879 194 0.011
intracellular transport GO:0046907 77 0.010
Human
regulation of protein ubiquitination GO:0031396 3 0.010
negative regulation of cell communication GO:0010648 61 0.010
single organism catabolic process GO:0044712 129 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
actomyosin structure organization GO:0031032 154 0.010
nucleotide catabolic process GO:0009166 77 0.010
protein modification by small protein conjugation GO:0032446 31 0.010
positive regulation of cellular biosynthetic process GO:0031328 109 0.010
axon development GO:0061564 163 0.010

aka-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
gastrointestinal system cancer DOID:3119 0 0.011
female reproductive organ cancer DOID:120 0 0.011
reproductive organ cancer DOID:193 0 0.011
disease of anatomical entity DOID:7 0 0.011