Caenorhabditis elegans

41 known processes

egl-21 (CELE_F01D4.4)

Protein EGL-21

egl-21 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.789
establishment of localization GO:0051234 1171 0.437
embryo development ending in birth or egg hatching GO:0009792 2992 0.384
transport GO:0006810 1093 0.363
locomotion GO:0040011 1634 0.349
Worm
post embryonic development GO:0009791 2152 0.324
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.256
Mouse
multicellular organism reproduction GO:0032504 819 0.230
regulation of biological quality GO:0065008 741 0.228
macromolecule localization GO:0033036 771 0.204
multicellular organismal aging GO:0010259 812 0.204
signaling GO:0023052 401 0.195
single organism localization GO:1902578 518 0.194
behavior GO:0007610 527 0.194
regulation of multicellular organismal process GO:0051239 726 0.193
cellular component movement GO:0006928 388 0.189
multi multicellular organism process GO:0044706 390 0.158
cell cycle GO:0007049 526 0.144
regulation of gene expression GO:0010468 366 0.138
Mouse
oviposition GO:0018991 364 0.133
macromolecular complex subunit organization GO:0043933 320 0.128
determination of adult lifespan GO:0008340 812 0.125
growth GO:0040007 562 0.122
single organism transport GO:0044765 447 0.121
regulation of metabolic process GO:0019222 478 0.121
Mouse
gene expression GO:0010467 412 0.114
negative regulation of biological process GO:0048519 567 0.114
Mouse
regulation of signaling GO:0023051 172 0.113
multi organism reproductive behavior GO:0044705 387 0.112
single organism signaling GO:0044700 401 0.109
multicellular organismal reproductive behavior GO:0033057 384 0.103
negative regulation of macromolecule metabolic process GO:0010605 229 0.101
Mouse
regulation of response to stimulus GO:0048583 243 0.097
regulation of developmental process GO:0050793 684 0.097
regulation of cell communication GO:0010646 176 0.095
regulation of cellular metabolic process GO:0031323 305 0.095
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.093
multi organism behavior GO:0051705 389 0.088
cellular localization GO:0051641 360 0.088
multicellular organismal reproductive process GO:0048609 815 0.086
organelle organization GO:0006996 783 0.085
organ development GO:0048513 1102 0.085
Zebrafish
signal transduction GO:0007165 317 0.084
aging GO:0007568 812 0.082
maintenance of location GO:0051235 580 0.080
lipid storage GO:0019915 565 0.077
localization of cell GO:0051674 313 0.077
lipid localization GO:0010876 573 0.074
regulation of growth GO:0040008 409 0.073
regulation of developmental growth GO:0048638 389 0.072
reproductive behavior GO:0019098 387 0.072
cell cycle process GO:0022402 482 0.071
macromolecule biosynthetic process GO:0009059 250 0.067
Mouse
purine ribonucleoside metabolic process GO:0046128 92 0.067
regulation of primary metabolic process GO:0080090 292 0.066
Mouse
multi organism reproductive process GO:0044703 867 0.066
biosynthetic process GO:0009058 323 0.065
Mouse
developmental growth GO:0048589 412 0.064
aromatic compound biosynthetic process GO:0019438 192 0.064
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 250 0.063
developmental process involved in reproduction GO:0003006 1165 0.062
nucleobase containing compound metabolic process GO:0006139 406 0.058
Mouse
positive regulation of gene expression GO:0010628 112 0.057
neurogenesis GO:0022008 236 0.056
vesicle mediated transport GO:0016192 852 0.055
sexual reproduction GO:0019953 546 0.055
regulation of macromolecule biosynthetic process GO:0010556 189 0.055
Mouse
single organism reproductive process GO:0044702 1196 0.055
positive regulation of rna metabolic process GO:0051254 103 0.054
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.053
Mouse
cell development GO:0048468 696 0.053
receptor mediated endocytosis GO:0006898 715 0.051
regulation of locomotion GO:0040012 161 0.050
endocytosis GO:0006897 819 0.050
protein localization GO:0008104 205 0.049
positive regulation of biosynthetic process GO:0009891 109 0.049
ribonucleoside triphosphate metabolic process GO:0009199 87 0.048
cellular biosynthetic process GO:0044249 315 0.047
Mouse
multicellular organism growth GO:0035264 385 0.047
secretion by cell GO:0032940 138 0.046
regulation of cellular biosynthetic process GO:0031326 189 0.044
Mouse
cell projection organization GO:0030030 231 0.044
positive regulation of growth GO:0045927 369 0.043
single organism behavior GO:0044708 83 0.043
establishment of localization in cell GO:0051649 318 0.041
organic substance biosynthetic process GO:1901576 323 0.040
Mouse
catabolic process GO:0009056 318 0.040
spicule insertion GO:0034609 2 0.039
protein catabolic process GO:0030163 162 0.039
nervous system development GO:0007399 253 0.037
regulation of multicellular organism growth GO:0040014 373 0.037
cell cell signaling GO:0007267 118 0.037
peptide hormone processing GO:0016486 2 0.037
Mouse
cell motility GO:0048870 313 0.036
protein metabolic process GO:0019538 422 0.035
body morphogenesis GO:0010171 620 0.034
negative regulation of metabolic process GO:0009892 240 0.034
Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.033
regulation of biosynthetic process GO:0009889 189 0.033
Mouse
regulation of behavior GO:0050795 97 0.033
positive regulation of developmental process GO:0051094 408 0.033
organelle fission GO:0048285 363 0.032
regulation of signal transduction GO:0009966 135 0.031
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.031
small molecule metabolic process GO:0044281 186 0.031
gonad development GO:0008406 840 0.031
nucleoside triphosphate metabolic process GO:0009141 87 0.030
regulation of localization GO:0032879 194 0.030
regulation of multicellular organismal development GO:2000026 317 0.030
cellular macromolecule biosynthetic process GO:0034645 247 0.030
Mouse
regulation of organelle organization GO:0033043 164 0.029
cellular nitrogen compound catabolic process GO:0044270 119 0.028
negative regulation of developmental process GO:0051093 227 0.028
negative regulation of cellular metabolic process GO:0031324 95 0.027
Mouse
cell surface receptor signaling pathway GO:0007166 149 0.027
organic cyclic compound biosynthetic process GO:1901362 195 0.027
Mouse
muscle structure development GO:0061061 191 0.026
cellular protein metabolic process GO:0044267 279 0.026
cellular component assembly GO:0022607 293 0.026
genitalia development GO:0048806 741 0.026
negative regulation of cell cycle GO:0045786 53 0.026
ribonucleoside catabolic process GO:0042454 77 0.025
positive regulation of cellular metabolic process GO:0031325 178 0.025
positive regulation of macromolecule metabolic process GO:0010604 149 0.025
cell part morphogenesis GO:0032990 152 0.024
aromatic compound catabolic process GO:0019439 116 0.024
oogenesis GO:0048477 229 0.023
gamete generation GO:0007276 461 0.023
molting cycle GO:0042303 281 0.023
negative regulation of cellular process GO:0048523 239 0.023
Mouse
meiotic cell cycle GO:0051321 335 0.022
neuron projection development GO:0031175 187 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.022
Mouse
regulation of cellular component organization GO:0051128 248 0.022
establishment of organelle localization GO:0051656 123 0.022
hormone metabolic process GO:0042445 3 0.021
Mouse
single organism intracellular transport GO:1902582 70 0.021
cell migration GO:0016477 306 0.021
protein complex assembly GO:0006461 186 0.021
apical junction assembly GO:0043297 1 0.021
organ morphogenesis GO:0009887 67 0.021
hermaphrodite genitalia development GO:0040035 734 0.021
cellular component biogenesis GO:0044085 297 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
cell death GO:0008219 547 0.020
tube development GO:0035295 126 0.020
chromosome segregation GO:0007059 180 0.019
g protein coupled receptor signaling pathway GO:0007186 46 0.019
generation of neurons GO:0048699 235 0.019
purine nucleotide metabolic process GO:0006163 95 0.019
positive regulation of cellular biosynthetic process GO:0031328 109 0.018
transcription from rna polymerase ii promoter GO:0006366 149 0.018
reproductive system development GO:0061458 850 0.018
positive regulation of developmental growth GO:0048639 354 0.018
organic cyclic compound catabolic process GO:1901361 119 0.017
organelle assembly GO:0070925 214 0.017
reproductive structure development GO:0048608 850 0.017
neuron differentiation GO:0030182 217 0.017
protein complex biogenesis GO:0070271 186 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.017
cellular component morphogenesis GO:0032989 318 0.017
gene silencing GO:0016458 143 0.017
organelle localization GO:0051640 127 0.017
sex differentiation GO:0007548 909 0.017
cellular catabolic process GO:0044248 199 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.016
microtubule based process GO:0007017 182 0.016
cytoskeleton organization GO:0007010 339 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
macromolecule catabolic process GO:0009057 202 0.016
negative regulation of gene expression epigenetic GO:0045814 2 0.016
negative regulation of gene expression GO:0010629 217 0.016
purine containing compound metabolic process GO:0072521 95 0.015
purine nucleoside metabolic process GO:0042278 92 0.015
negative regulation of response to stimulus GO:0048585 73 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.015
Mouse
positive regulation of multicellular organismal process GO:0051240 417 0.015
protein modification process GO:0036211 207 0.015
intracellular signal transduction GO:0035556 96 0.015
nucleobase containing compound catabolic process GO:0034655 114 0.015
development of primary sexual characteristics GO:0045137 840 0.015
purine nucleoside triphosphate catabolic process GO:0009146 72 0.015
dauer larval development GO:0040024 92 0.014
purine ribonucleoside catabolic process GO:0046130 75 0.014
intracellular transport GO:0046907 77 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
digestive tract development GO:0048565 122 0.014
organic substance transport GO:0071702 113 0.014
female gamete generation GO:0007292 254 0.014
posttranscriptional regulation of gene expression GO:0010608 166 0.013
nucleic acid metabolic process GO:0090304 299 0.013
Mouse
heterocycle catabolic process GO:0046700 119 0.013
meiotic nuclear division GO:0007126 300 0.013
axon development GO:0061564 163 0.013
macromolecular complex assembly GO:0065003 193 0.013
neuron development GO:0048666 199 0.013
mitotic nuclear division GO:0007067 89 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 3 0.012
ribonucleoside triphosphate catabolic process GO:0009203 72 0.012
organic substance catabolic process GO:1901575 294 0.012
positive regulation of metabolic process GO:0009893 187 0.012
response to external biotic stimulus GO:0043207 101 0.012
purine nucleotide catabolic process GO:0006195 75 0.012
phagocytosis GO:0006909 115 0.012
ribonucleotide catabolic process GO:0009261 75 0.012
response to biotic stimulus GO:0009607 101 0.011
regulation of nucleic acid templated transcription GO:1903506 165 0.011
Mouse
regulation of cell cycle process GO:0010564 145 0.011
locomotory behavior GO:0007626 40 0.011
nucleoside catabolic process GO:0009164 78 0.011
germ cell development GO:0007281 351 0.011
positive regulation of cellular process GO:0048522 332 0.011
cellular protein modification process GO:0006464 207 0.011
adult behavior GO:0030534 3 0.011
regulation of secretion by cell GO:1903530 21 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.011
response to abiotic stimulus GO:0009628 152 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.011
positive regulation of nucleic acid templated transcription GO:1903508 102 0.010
heterocycle biosynthetic process GO:0018130 187 0.010
Mouse
ribose phosphate metabolic process GO:0019693 99 0.010
nucleoside phosphate metabolic process GO:0006753 108 0.010
phosphorus metabolic process GO:0006793 232 0.010
single organism organelle organization GO:1902589 501 0.010

egl-21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.046
muscle tissue disease DOID:66 0 0.046
disease of anatomical entity DOID:7 0 0.046
musculoskeletal system disease DOID:17 0 0.046
cancer DOID:162 0 0.045
disease of cellular proliferation DOID:14566 0 0.045
myopathy DOID:423 0 0.038
cardiovascular system disease DOID:1287 0 0.038
heart disease DOID:114 0 0.038
cardiomyopathy DOID:0050700 0 0.038
intrinsic cardiomyopathy DOID:0060036 0 0.024
dilated cardiomyopathy DOID:12930 0 0.024
charcot marie tooth disease DOID:10595 0 0.016
neuropathy DOID:870 0 0.016
nervous system disease DOID:863 0 0.016
charcot marie tooth disease type 2 DOID:0050539 0 0.016
neuromuscular disease DOID:440 0 0.016
disease of metabolism DOID:0014667 0 0.012
carbohydrate metabolic disorder DOID:2978 0 0.012
inherited metabolic disorder DOID:655 0 0.012
organ system cancer DOID:0050686 0 0.011