Caenorhabditis elegans

21 known processes

nekl-3 (CELE_F19H6.1)

Protein NEKL-3

nekl-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
reproductive structure development GO:0048608 850 0.668
embryo development GO:0009790 3052 0.542
Worm
organ development GO:0048513 1102 0.473
embryo development ending in birth or egg hatching GO:0009792 2992 0.418
Worm
reproductive system development GO:0061458 850 0.382
genitalia development GO:0048806 741 0.363
development of primary sexual characteristics GO:0045137 840 0.332
developmental process involved in reproduction GO:0003006 1165 0.288
gonad development GO:0008406 840 0.276
behavior GO:0007610 527 0.227
Worm
head development GO:0060322 1 0.204
hermaphrodite genitalia development GO:0040035 734 0.197
multicellular organismal reproductive behavior GO:0033057 384 0.178
regulation of primary metabolic process GO:0080090 292 0.161
Human
oviposition GO:0018991 364 0.157
regulation of metabolic process GO:0019222 478 0.156
Human
sex differentiation GO:0007548 909 0.142
single organism transport GO:0044765 447 0.139
macromolecule modification GO:0043412 218 0.132
Human
single organism reproductive process GO:0044702 1196 0.125
locomotion GO:0040011 1634 0.118
cellular localization GO:0051641 360 0.115
multicellular organismal reproductive process GO:0048609 815 0.114
multi organism reproductive behavior GO:0044705 387 0.112
multi organism behavior GO:0051705 389 0.111
cell development GO:0048468 696 0.107
Worm
multi multicellular organism process GO:0044706 390 0.103
determination of adult lifespan GO:0008340 812 0.103
regulation of macromolecule metabolic process GO:0060255 421 0.102
Human
protein metabolic process GO:0019538 422 0.096
Human
signaling GO:0023052 401 0.095
Human
gene expression GO:0010467 412 0.091
neuron differentiation GO:0030182 217 0.088
cellular component movement GO:0006928 388 0.086
microtubule based process GO:0007017 182 0.084
biosynthetic process GO:0009058 323 0.081
ion transport GO:0006811 113 0.078
single organism localization GO:1902578 518 0.078
multi organism reproductive process GO:0044703 867 0.075
cell cycle GO:0007049 526 0.075
Human
aromatic compound biosynthetic process GO:0019438 192 0.073
meiotic nuclear division GO:0007126 300 0.067
embryonic morphogenesis GO:0048598 152 0.066
apoptotic process GO:0006915 478 0.065
cellular component morphogenesis GO:0032989 318 0.064
negative regulation of biological process GO:0048519 567 0.064
organonitrogen compound metabolic process GO:1901564 151 0.064
multicellular organism reproduction GO:0032504 819 0.063
multicellular organismal aging GO:0010259 812 0.062
tissue development GO:0009888 112 0.061
negative regulation of macromolecule metabolic process GO:0010605 229 0.061
positive regulation of multicellular organismal process GO:0051240 417 0.060
cell surface receptor signaling pathway GO:0007166 149 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.060
regulation of protein metabolic process GO:0051246 81 0.059
Human
neurogenesis GO:0022008 236 0.058
cell migration GO:0016477 306 0.058
establishment of localization in cell GO:0051649 318 0.058
reproductive behavior GO:0019098 387 0.058
single organism cellular localization GO:1902580 72 0.056
response to bacterium GO:0009617 86 0.056
regulation of gene expression GO:0010468 366 0.056
single organism organelle organization GO:1902589 501 0.056
Human
macromolecule localization GO:0033036 771 0.055
aging GO:0007568 812 0.055
transport GO:0006810 1093 0.055
muscle structure development GO:0061061 191 0.054
Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.053
regulation of biological quality GO:0065008 741 0.051
regionalization GO:0003002 31 0.051
cellular protein metabolic process GO:0044267 279 0.050
Human
nucleic acid metabolic process GO:0090304 299 0.049
regulation of phosphate metabolic process GO:0019220 81 0.049
defense response GO:0006952 296 0.049
lipid localization GO:0010876 573 0.048
response to external stimulus GO:0009605 289 0.048
maintenance of location GO:0051235 580 0.048
heterocycle biosynthetic process GO:0018130 187 0.048
positive regulation of growth GO:0045927 369 0.048
growth GO:0040007 562 0.048
oogenesis GO:0048477 229 0.047
protein modification process GO:0036211 207 0.046
Human
positive regulation of cellular metabolic process GO:0031325 178 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.045
regulation of cellular metabolic process GO:0031323 305 0.045
Human
cytoskeleton organization GO:0007010 339 0.045
sensory organ morphogenesis GO:0090596 2 0.044
lipid storage GO:0019915 565 0.044
response to wounding GO:0009611 4 0.044
localization of cell GO:0051674 313 0.044
cellular biosynthetic process GO:0044249 315 0.043
organelle organization GO:0006996 783 0.043
Human
nucleobase containing compound metabolic process GO:0006139 406 0.042
negative regulation of multicellular organismal process GO:0051241 236 0.042
single organism signaling GO:0044700 401 0.042
Human
response to chemical GO:0042221 356 0.041
rna metabolic process GO:0016070 228 0.041
system process GO:0003008 136 0.041
transcription dna templated GO:0006351 168 0.040
regulation of cell communication GO:0010646 176 0.040
Human
regulation of locomotion GO:0040012 161 0.040
programmed cell death GO:0012501 500 0.039
cellular protein modification process GO:0006464 207 0.038
Human
gamete generation GO:0007276 461 0.038
tube development GO:0035295 126 0.037
response to external biotic stimulus GO:0043207 101 0.037
regulation of nucleic acid templated transcription GO:1903506 165 0.037
cell morphogenesis GO:0000902 163 0.037
cell division GO:0051301 262 0.037
Human
death GO:0016265 547 0.036
negative regulation of cellular metabolic process GO:0031324 95 0.036
cell proliferation GO:0008283 116 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.035
muscle fiber development GO:0048747 2 0.034
Worm
nervous system development GO:0007399 253 0.034
response to other organism GO:0051707 101 0.034
nucleic acid templated transcription GO:0097659 169 0.034
establishment of localization GO:0051234 1171 0.034
macromolecular complex subunit organization GO:0043933 320 0.034
eating behavior GO:0042755 59 0.034
Worm
positive regulation of metabolic process GO:0009893 187 0.033
post embryonic development GO:0009791 2152 0.033
Worm
regulation of localization GO:0032879 194 0.033
positive regulation of macromolecule metabolic process GO:0010604 149 0.032
defense response to gram negative bacterium GO:0050829 64 0.032
regulation of cellular biosynthetic process GO:0031326 189 0.031
phosphate containing compound metabolic process GO:0006796 232 0.031
Human
sexual reproduction GO:0019953 546 0.030
regulation of multicellular organismal process GO:0051239 726 0.030
tissue morphogenesis GO:0048729 65 0.030
regulation of cellular component organization GO:0051128 248 0.030
Human
cell morphogenesis involved in differentiation GO:0000904 112 0.029
regulation of phosphorus metabolic process GO:0051174 81 0.029
regulation of cell development GO:0060284 49 0.029
cellular macromolecule biosynthetic process GO:0034645 247 0.029
protein localization GO:0008104 205 0.029
signal transduction GO:0007165 317 0.029
Human
cellular nitrogen compound biosynthetic process GO:0044271 192 0.029
striated muscle cell development GO:0055002 157 0.029
Worm
developmental growth GO:0048589 412 0.029
organic cyclic compound biosynthetic process GO:1901362 195 0.028
cell cell signaling GO:0007267 118 0.028
cell motility GO:0048870 313 0.028
small molecule metabolic process GO:0044281 186 0.028
regulation of multicellular organism growth GO:0040014 373 0.027
regulation of developmental process GO:0050793 684 0.027
regulation of rna metabolic process GO:0051252 173 0.027
taxis GO:0042330 128 0.026
positive regulation of developmental growth GO:0048639 354 0.026
endocytosis GO:0006897 819 0.026
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.025
larval behavior GO:0030537 5 0.025
Worm
cellular protein complex assembly GO:0043623 178 0.025
regulation of phosphorylation GO:0042325 45 0.025
regulation of growth GO:0040008 409 0.025
transcription from rna polymerase ii promoter GO:0006366 149 0.025
rna biosynthetic process GO:0032774 169 0.025
regulation of cellular protein metabolic process GO:0032268 75 0.025
Human
neurotransmitter metabolic process GO:0042133 6 0.025
single organism intracellular transport GO:1902582 70 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.024
cell death GO:0008219 547 0.024
organelle fission GO:0048285 363 0.024
Human
macromolecule biosynthetic process GO:0009059 250 0.024
epithelial cell proliferation GO:0050673 1 0.024
regulation of macromolecule biosynthetic process GO:0010556 189 0.024
epithelium development GO:0060429 68 0.023
phosphorylation GO:0016310 116 0.023
Human
positive regulation of developmental process GO:0051094 408 0.023
nucleobase containing compound biosynthetic process GO:0034654 184 0.022
organic substance biosynthetic process GO:1901576 323 0.022
response to organic substance GO:0010033 131 0.022
cell projection organization GO:0030030 231 0.022
intracellular signal transduction GO:0035556 96 0.022
Human
cellular response to chemical stimulus GO:0070887 129 0.021
oocyte development GO:0048599 44 0.021
positive regulation of multicellular organism growth GO:0040018 352 0.021
generation of neurons GO:0048699 235 0.021
multicellular organism growth GO:0035264 385 0.021
transmembrane transport GO:0055085 110 0.021
mitotic cell cycle process GO:1903047 194 0.021
Human
protein complex subunit organization GO:0071822 280 0.021
carbohydrate derivative metabolic process GO:1901135 141 0.020
regulation of nitrogen compound metabolic process GO:0051171 222 0.020
regulation of organelle organization GO:0033043 164 0.020
Human
negative regulation of response to stimulus GO:0048585 73 0.019
vesicle mediated transport GO:0016192 852 0.019
positive regulation of cellular component organization GO:0051130 34 0.019
body morphogenesis GO:0010171 620 0.019
establishment of organelle localization GO:0051656 123 0.019
actin cytoskeleton organization GO:0030036 184 0.019
regulation of multicellular organismal development GO:2000026 317 0.019
cell projection morphogenesis GO:0048858 148 0.019
defense response to other organism GO:0098542 100 0.019
female gamete generation GO:0007292 254 0.019
digestive tract development GO:0048565 122 0.018
posttranscriptional gene silencing GO:0016441 143 0.018
meiotic cell cycle GO:0051321 335 0.018
oxoacid metabolic process GO:0043436 47 0.018
muscle cell development GO:0055001 158 0.018
Worm
positive regulation of biosynthetic process GO:0009891 109 0.018
purine ribonucleoside metabolic process GO:0046128 92 0.017
regulation of apoptotic signaling pathway GO:2001233 1 0.017
regulation of rna biosynthetic process GO:2001141 165 0.017
protein complex biogenesis GO:0070271 186 0.017
regulation of cellular localization GO:0060341 42 0.017
cellular component assembly involved in morphogenesis GO:0010927 183 0.017
actin filament based process GO:0030029 191 0.017
neuron projection morphogenesis GO:0048812 114 0.017
negative regulation of gene expression GO:0010629 217 0.017
cation transport GO:0006812 78 0.017
cellular macromolecular complex assembly GO:0034622 184 0.017
response to biotic stimulus GO:0009607 101 0.016
vulval development GO:0040025 333 0.016
negative regulation of metabolic process GO:0009892 240 0.016
protein phosphorylation GO:0006468 85 0.016
Human
receptor mediated endocytosis GO:0006898 715 0.016
defense response to bacterium GO:0042742 86 0.016
organic acid metabolic process GO:0006082 47 0.016
carboxylic acid metabolic process GO:0019752 34 0.016
positive regulation of intracellular transport GO:0032388 2 0.015
single organism behavior GO:0044708 83 0.015
Worm
response to nutrient levels GO:0031667 35 0.015
feeding behavior GO:0007631 70 0.015
Worm
germ cell development GO:0007281 351 0.015
positive regulation of response to stimulus GO:0048584 55 0.015
Human
developmental growth involved in morphogenesis GO:0060560 37 0.014
actomyosin structure organization GO:0031032 154 0.014
anion transport GO:0006820 30 0.014
secretion GO:0046903 147 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.013
inductive cell migration GO:0040039 145 0.013
myosin filament organization GO:0031033 138 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
axon development GO:0061564 163 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
regulation of anatomical structure size GO:0090066 46 0.013
negative regulation of nucleic acid templated transcription GO:1903507 53 0.013
neuron projection development GO:0031175 187 0.013
neurological system process GO:0050877 53 0.013
single organism biosynthetic process GO:0044711 91 0.013
regulation of multi organism process GO:0043900 69 0.013
cellular amino acid metabolic process GO:0006520 15 0.012
positive regulation of molecular function GO:0044093 61 0.012
regulation of signaling GO:0023051 172 0.012
Human
negative regulation of cellular process GO:0048523 239 0.012
regulation of feeding behavior GO:0060259 38 0.012
pharyngeal pumping GO:0043050 58 0.012
Worm
regulation of biosynthetic process GO:0009889 189 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
regulation of catalytic activity GO:0050790 78 0.011
post embryonic organ development GO:0048569 336 0.011
organelle assembly GO:0070925 214 0.011
cellular response to stress GO:0033554 162 0.011
Human
positive regulation of rna biosynthetic process GO:1902680 102 0.011
regulation of cell motility GO:2000145 57 0.011
muscle cell differentiation GO:0042692 171 0.011
Worm
positive regulation of cellular process GO:0048522 332 0.011
Human
digestive system development GO:0055123 122 0.011
response to endoplasmic reticulum stress GO:0034976 71 0.011
cytokinesis GO:0000910 80 0.011
regulation of ion transport GO:0043269 39 0.011
protein complex assembly GO:0006461 186 0.011
regulation of nematode larval development GO:0061062 260 0.011
regulation of reproductive process GO:2000241 66 0.011
regulation of gene expression epigenetic GO:0040029 163 0.011
mapk cascade GO:0000165 31 0.010
regulation of protein targeting GO:1903533 3 0.010
cellular protein localization GO:0034613 75 0.010
intracellular transport GO:0046907 77 0.010
signal transduction by phosphorylation GO:0023014 31 0.010
regulation of cellular component size GO:0032535 40 0.010
nucleobase containing small molecule metabolic process GO:0055086 115 0.010
cellular response to organic substance GO:0071310 119 0.010
establishment or maintenance of cell polarity GO:0007163 63 0.010

nekl-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011