Caenorhabditis elegans

4 known processes

thn-2 (CELE_F28D1.5)

Protein THN-2

thn-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune response GO:0006955 192 0.500
Worm
embryo development ending in birth or egg hatching GO:0009792 2992 0.339
embryo development GO:0009790 3052 0.337
aging GO:0007568 812 0.318
Worm
innate immune response GO:0045087 190 0.318
Worm
multicellular organismal aging GO:0010259 812 0.315
Worm
determination of adult lifespan GO:0008340 812 0.268
Worm
endocytosis GO:0006897 819 0.198
post embryonic development GO:0009791 2152 0.191
transport GO:0006810 1093 0.189
locomotion GO:0040011 1634 0.184
establishment of localization GO:0051234 1171 0.157
response to external stimulus GO:0009605 289 0.156
Worm
growth GO:0040007 562 0.156
defense response GO:0006952 296 0.141
response to biotic stimulus GO:0009607 101 0.137
Worm
defense response to other organism GO:0098542 100 0.134
Worm
vesicle mediated transport GO:0016192 852 0.109
organ development GO:0048513 1102 0.104
defense response to fungus GO:0050832 19 0.095
defense response to bacterium GO:0042742 86 0.087
Worm
developmental growth GO:0048589 412 0.087
response to other organism GO:0051707 101 0.087
Worm
receptor mediated endocytosis GO:0006898 715 0.083
response to chemical GO:0042221 356 0.083
single organism localization GO:1902578 518 0.077
single organism reproductive process GO:0044702 1196 0.075
multicellular organismal reproductive process GO:0048609 815 0.073
multi multicellular organism process GO:0044706 390 0.072
regulation of biological quality GO:0065008 741 0.071
catabolic process GO:0009056 318 0.071
multi organism reproductive process GO:0044703 867 0.070
cellular catabolic process GO:0044248 199 0.069
macromolecule localization GO:0033036 771 0.065
macromolecule catabolic process GO:0009057 202 0.064
defense response to gram negative bacterium GO:0050829 64 0.063
Worm
developmental process involved in reproduction GO:0003006 1165 0.063
multi organism reproductive behavior GO:0044705 387 0.062
maintenance of location GO:0051235 580 0.062
response to external biotic stimulus GO:0043207 101 0.061
Worm
reproductive structure development GO:0048608 850 0.059
regulation of developmental process GO:0050793 684 0.059
oviposition GO:0018991 364 0.059
lipid localization GO:0010876 573 0.057
reproductive system development GO:0061458 850 0.057
response to wounding GO:0009611 4 0.057
lipid storage GO:0019915 565 0.056
positive regulation of multicellular organism growth GO:0040018 352 0.054
regulation of multicellular organism growth GO:0040014 373 0.053
reproductive behavior GO:0019098 387 0.053
response to bacterium GO:0009617 86 0.052
Worm
behavior GO:0007610 527 0.050
positive regulation of multicellular organismal process GO:0051240 417 0.050
body morphogenesis GO:0010171 620 0.050
organic substance catabolic process GO:1901575 294 0.049
cell development GO:0048468 696 0.049
development of primary sexual characteristics GO:0045137 840 0.049
single organism transport GO:0044765 447 0.048
regulation of multicellular organismal process GO:0051239 726 0.048
multicellular organismal reproductive behavior GO:0033057 384 0.047
multicellular organism reproduction GO:0032504 819 0.047
death GO:0016265 547 0.046
sex differentiation GO:0007548 909 0.046
protein metabolic process GO:0019538 422 0.046
positive regulation of developmental process GO:0051094 408 0.046
multi organism behavior GO:0051705 389 0.043
positive regulation of developmental growth GO:0048639 354 0.043
multicellular organism growth GO:0035264 385 0.041
hermaphrodite genitalia development GO:0040035 734 0.041
gonad development GO:0008406 840 0.041
molting cycle GO:0042303 281 0.040
cellular response to chemical stimulus GO:0070887 129 0.040
positive regulation of growth GO:0045927 369 0.040
regeneration GO:0031099 4 0.039
regulation of developmental growth GO:0048638 389 0.039
cellular localization GO:0051641 360 0.039
cellular protein metabolic process GO:0044267 279 0.038
organelle organization GO:0006996 783 0.037
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.035
tissue development GO:0009888 112 0.034
regulation of growth GO:0040008 409 0.034
small molecule metabolic process GO:0044281 186 0.033
secretion GO:0046903 147 0.032
nucleobase containing compound metabolic process GO:0006139 406 0.031
cell death GO:0008219 547 0.031
genitalia development GO:0048806 741 0.031
macromolecular complex subunit organization GO:0043933 320 0.029
programmed cell death GO:0012501 500 0.027
response to organic substance GO:0010033 131 0.027
vulval development GO:0040025 333 0.026
single organism catabolic process GO:0044712 129 0.026
organic substance biosynthetic process GO:1901576 323 0.025
cellular component movement GO:0006928 388 0.025
organonitrogen compound metabolic process GO:1901564 151 0.023
meiotic nuclear division GO:0007126 300 0.023
defense response to gram positive bacterium GO:0050830 31 0.022
cellular response to organic substance GO:0071310 119 0.022
biosynthetic process GO:0009058 323 0.021
negative regulation of vulval development GO:0040027 206 0.021
cell cycle process GO:0022402 482 0.021
cellular macromolecule catabolic process GO:0044265 73 0.021
single organism organelle organization GO:1902589 501 0.020
nucleic acid metabolic process GO:0090304 299 0.020
oxoacid metabolic process GO:0043436 47 0.020
phosphate containing compound metabolic process GO:0006796 232 0.020
small molecule biosynthetic process GO:0044283 38 0.020
cytoskeleton organization GO:0007010 339 0.019
organelle fission GO:0048285 363 0.019
cellular response to endogenous stimulus GO:0071495 32 0.019
protein complex assembly GO:0006461 186 0.019
negative regulation of biological process GO:0048519 567 0.019
male sex differentiation GO:0046661 86 0.019
cellular component morphogenesis GO:0032989 318 0.019
response to abiotic stimulus GO:0009628 152 0.019
cellular component assembly GO:0022607 293 0.018
chromosome segregation GO:0007059 180 0.018
protein complex subunit organization GO:0071822 280 0.018
proteolysis GO:0006508 61 0.018
collagen and cuticulin based cuticle development GO:0040002 99 0.018
negative regulation of gene expression GO:0010629 217 0.018
post embryonic organ development GO:0048569 336 0.017
cellular component biogenesis GO:0044085 297 0.017
organic acid metabolic process GO:0006082 47 0.017
apoptotic process GO:0006915 478 0.017
cuticle development GO:0042335 100 0.017
response to acid chemical GO:0001101 4 0.017
phosphorus metabolic process GO:0006793 232 0.017
regulation of multicellular organismal development GO:2000026 317 0.017
regulation of primary metabolic process GO:0080090 292 0.016
head development GO:0060322 1 0.016
cellular nitrogen compound catabolic process GO:0044270 119 0.016
regulation of post embryonic development GO:0048580 260 0.016
protein complex biogenesis GO:0070271 186 0.016
cellular protein complex assembly GO:0043623 178 0.016
cellular biosynthetic process GO:0044249 315 0.016
neuron projection development GO:0031175 187 0.016
cell cycle GO:0007049 526 0.016
cell division GO:0051301 262 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
carboxylic acid metabolic process GO:0019752 34 0.015
sexual reproduction GO:0019953 546 0.015
negative regulation of nematode larval development GO:0061064 208 0.015
macromolecular complex assembly GO:0065003 193 0.015
secretion by cell GO:0032940 138 0.015
negative regulation of cellular process GO:0048523 239 0.015
nervous system development GO:0007399 253 0.014
heterocycle catabolic process GO:0046700 119 0.014
organic cyclic compound catabolic process GO:1901361 119 0.014
establishment of localization in cell GO:0051649 318 0.014
macromolecule biosynthetic process GO:0009059 250 0.014
negative regulation of post embryonic development GO:0048581 208 0.014
nucleobase containing compound catabolic process GO:0034655 114 0.014
regulation of metabolic process GO:0019222 478 0.014
negative regulation of developmental process GO:0051093 227 0.014
aromatic compound catabolic process GO:0019439 116 0.014
positive regulation of cellular process GO:0048522 332 0.014
cellular response to hormone stimulus GO:0032870 14 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.014
actomyosin structure organization GO:0031032 154 0.013
cellular macromolecular complex assembly GO:0034622 184 0.013
muscle structure development GO:0061061 191 0.013
myosin filament organization GO:0031033 138 0.013
neuromuscular junction development GO:0007528 2 0.013
protein catabolic process GO:0030163 162 0.013
posttranscriptional gene silencing GO:0016441 143 0.013
gene silencing GO:0016458 143 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
signaling GO:0023052 401 0.013
organelle assembly GO:0070925 214 0.013
protein modification process GO:0036211 207 0.013
negative regulation of multicellular organismal process GO:0051241 236 0.012
actin filament based process GO:0030029 191 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
meiotic cell cycle GO:0051321 335 0.012
negative regulation of macromolecule metabolic process GO:0010605 229 0.012
gamete generation GO:0007276 461 0.012
response to endogenous stimulus GO:0009719 33 0.012
transmembrane transport GO:0055085 110 0.012
meiotic chromosome segregation GO:0045132 139 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
rna interference GO:0016246 137 0.012
gene silencing by rna GO:0031047 143 0.012
sensory organ morphogenesis GO:0090596 2 0.012
regulation of nematode larval development GO:0061062 260 0.012
protein oligomerization GO:0051259 4 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
membrane invagination GO:0010324 98 0.011
positive regulation of cell migration GO:0030335 3 0.011
negative regulation of gene expression epigenetic GO:0045814 2 0.011
regulation of vulval development GO:0040028 248 0.011
cellular component assembly involved in morphogenesis GO:0010927 183 0.011
response to temperature stimulus GO:0009266 66 0.011
cell type specific apoptotic process GO:0097285 4 0.011
single organism biosynthetic process GO:0044711 91 0.011
muscle cell differentiation GO:0042692 171 0.011
myosin filament assembly GO:0031034 138 0.011
posttranscriptional regulation of gene expression GO:0010608 166 0.011
apoptotic cell clearance GO:0043277 111 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
actin cytoskeleton organization GO:0030036 184 0.011
protein localization GO:0008104 205 0.011
regulation of macromolecule metabolic process GO:0060255 421 0.011
localization of cell GO:0051674 313 0.010
regulation of cell division GO:0051302 142 0.010
negative regulation of metabolic process GO:0009892 240 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
regulation of nucleocytoplasmic transport GO:0046822 3 0.010
organophosphate metabolic process GO:0019637 125 0.010
nucleotide metabolic process GO:0009117 108 0.010
positive regulation of intracellular transport GO:0032388 2 0.010
muscle cell development GO:0055001 158 0.010
engulfment of apoptotic cell GO:0043652 94 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.010

thn-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.011