Caenorhabditis elegans

38 known processes

ife-1 (CELE_F53A2.6)

Protein IFE-1

ife-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sexual reproduction GO:0019953 546 0.696
gamete generation GO:0007276 461 0.684
embryo development ending in birth or egg hatching GO:0009792 2992 0.657
female gamete generation GO:0007292 254 0.604
cell development GO:0048468 696 0.578
embryo development GO:0009790 3052 0.468
organelle organization GO:0006996 783 0.402
Worm Fly
multicellular organism reproduction GO:0032504 819 0.398
meiotic nuclear division GO:0007126 300 0.390
Worm Fly
germ cell development GO:0007281 351 0.372
post embryonic development GO:0009791 2152 0.366
Fly
multicellular organismal reproductive process GO:0048609 815 0.311
oogenesis GO:0048477 229 0.309
single organism reproductive process GO:0044702 1196 0.300
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.298
organelle fission GO:0048285 363 0.297
Worm Fly
locomotion GO:0040011 1634 0.264
multi organism reproductive process GO:0044703 867 0.251
meiotic cell cycle GO:0051321 335 0.185
Worm Fly
establishment of localization GO:0051234 1171 0.181
transport GO:0006810 1093 0.164
pole plasm assembly GO:0007315 2 0.163
nucleobase containing compound metabolic process GO:0006139 406 0.163
Fly
regulation of biological quality GO:0065008 741 0.156
Worm
cellular protein complex assembly GO:0043623 178 0.154
gonad development GO:0008406 840 0.147
organ development GO:0048513 1102 0.145
Fly
organic substance catabolic process GO:1901575 294 0.137
oocyte development GO:0048599 44 0.130
macromolecule localization GO:0033036 771 0.128
Worm
vesicle mediated transport GO:0016192 852 0.128
cellular component biogenesis GO:0044085 297 0.128
body morphogenesis GO:0010171 620 0.125
receptor mediated endocytosis GO:0006898 715 0.119
cellular macromolecular complex assembly GO:0034622 184 0.119
cellular component assembly GO:0022607 293 0.113
single organism organelle organization GO:1902589 501 0.111
Fly
developmental process involved in reproduction GO:0003006 1165 0.111
growth GO:0040007 562 0.110
Fly
protein localization GO:0008104 205 0.108
protein complex subunit organization GO:0071822 280 0.107
Fly
lipid localization GO:0010876 573 0.106
Worm
macromolecular complex assembly GO:0065003 193 0.090
regulation of developmental growth GO:0048638 389 0.088
protein complex assembly GO:0006461 186 0.087
positive regulation of metabolic process GO:0009893 187 0.085
Worm
positive regulation of gene expression GO:0010628 112 0.085
Worm
regulation of macromolecule metabolic process GO:0060255 421 0.085
Human Worm
macromolecule catabolic process GO:0009057 202 0.083
reproductive system development GO:0061458 850 0.082
aging GO:0007568 812 0.078
Worm
lipid storage GO:0019915 565 0.076
Worm
organelle assembly GO:0070925 214 0.074
endocytosis GO:0006897 819 0.073
regulation of multicellular organism growth GO:0040014 373 0.072
striated muscle cell development GO:0055002 157 0.072
protein complex biogenesis GO:0070271 186 0.071
macromolecular complex subunit organization GO:0043933 320 0.070
Fly
maintenance of location GO:0051235 580 0.068
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.068
cell death GO:0008219 547 0.068
Fly
oocyte differentiation GO:0009994 45 0.065
regulation of metabolic process GO:0019222 478 0.063
Human Worm
cellular biosynthetic process GO:0044249 315 0.063
Human Mouse Worm Fly
ribonucleoprotein complex assembly GO:0022618 4 0.062
neurogenesis GO:0022008 236 0.061
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.061
Worm
muscle cell development GO:0055001 158 0.059
regulation of meiotic cell cycle GO:0051445 136 0.058
developmental growth GO:0048589 412 0.058
positive regulation of macromolecule metabolic process GO:0010604 149 0.057
Worm
myofibril assembly GO:0030239 154 0.057
actomyosin structure organization GO:0031032 154 0.055
phosphate containing compound metabolic process GO:0006796 232 0.054
positive regulation of developmental growth GO:0048639 354 0.053
negative regulation of biological process GO:0048519 567 0.053
neuron development GO:0048666 199 0.053
cellular catabolic process GO:0044248 199 0.052
determination of adult lifespan GO:0008340 812 0.052
Worm
behavior GO:0007610 527 0.052
multicellular organismal aging GO:0010259 812 0.050
Worm
reproductive structure development GO:0048608 850 0.050
striated muscle cell differentiation GO:0051146 158 0.049
cell cycle GO:0007049 526 0.047
Human Worm Fly
regulation of developmental process GO:0050793 684 0.047
nucleic acid metabolic process GO:0090304 299 0.047
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.047
Human Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.047
catabolic process GO:0009056 318 0.046
anatomical structure formation involved in morphogenesis GO:0048646 250 0.046
positive regulation of growth GO:0045927 369 0.045
muscle structure development GO:0061061 191 0.045
cellular component morphogenesis GO:0032989 318 0.044
striated muscle myosin thick filament assembly GO:0071688 138 0.044
positive regulation of multicellular organism growth GO:0040018 352 0.044
single organism transport GO:0044765 447 0.043
single organism localization GO:1902578 518 0.043
development of primary sexual characteristics GO:0045137 840 0.043
meiotic cell cycle process GO:1903046 170 0.043
Worm Fly
actin filament based process GO:0030029 191 0.042
heterocycle catabolic process GO:0046700 119 0.042
cellular component assembly involved in morphogenesis GO:0010927 183 0.042
cell division GO:0051301 262 0.042
oocyte axis specification GO:0007309 2 0.042
myosin filament assembly GO:0031034 138 0.042
genitalia development GO:0048806 741 0.041
myosin filament organization GO:0031033 138 0.041
small molecule metabolic process GO:0044281 186 0.041
multicellular organism growth GO:0035264 385 0.041
muscle cell differentiation GO:0042692 171 0.040
cellular component movement GO:0006928 388 0.040
nucleotide metabolic process GO:0009117 108 0.040
regulation of growth GO:0040008 409 0.039
Fly
regulation of primary metabolic process GO:0080090 292 0.038
Human Worm
regulation of multicellular organismal process GO:0051239 726 0.038
nucleoside triphosphate metabolic process GO:0009141 87 0.038
nucleobase containing compound biosynthetic process GO:0034654 184 0.037
death GO:0016265 547 0.037
Fly
nucleotide catabolic process GO:0009166 77 0.037
vulval development GO:0040025 333 0.035
neuron differentiation GO:0030182 217 0.035
cell maturation GO:0048469 26 0.035
regulation of post embryonic development GO:0048580 260 0.035
cellular localization GO:0051641 360 0.034
oocyte construction GO:0007308 2 0.034
regulation of cellular metabolic process GO:0031323 305 0.034
Human Worm
organic substance biosynthetic process GO:1901576 323 0.033
Human Mouse Worm Fly
chemotaxis GO:0006935 120 0.033
chromosome organization GO:0051276 104 0.033
Fly
meiotic chromosome segregation GO:0045132 139 0.032
Worm Fly
cellular amine metabolic process GO:0044106 15 0.032
establishment of localization in cell GO:0051649 318 0.031
carbohydrate derivative metabolic process GO:1901135 141 0.031
cellular macromolecule catabolic process GO:0044265 73 0.030
nucleic acid templated transcription GO:0097659 169 0.030
nucleobase containing compound catabolic process GO:0034655 114 0.030
modification dependent protein catabolic process GO:0019941 32 0.030
apoptotic process GO:0006915 478 0.030
response to external stimulus GO:0009605 289 0.030
regulation of organelle organization GO:0033043 164 0.029
chromosome condensation GO:0030261 6 0.029
Fly
positive regulation of cellular biosynthetic process GO:0031328 109 0.029
Worm
cell cycle process GO:0022402 482 0.028
Human Worm Fly
programmed cell death GO:0012501 500 0.028
Fly
cellular protein metabolic process GO:0044267 279 0.028
Human Mouse Worm Fly
regulation of reproductive process GO:2000241 66 0.028
protein catabolic process GO:0030163 162 0.027
positive regulation of multicellular organismal process GO:0051240 417 0.026
taxis GO:0042330 128 0.026
multicellular organismal reproductive behavior GO:0033057 384 0.026
single organism cellular localization GO:1902580 72 0.026
ribonucleoside triphosphate metabolic process GO:0009199 87 0.026
macromolecule biosynthetic process GO:0009059 250 0.026
Human Mouse Worm Fly
organonitrogen compound metabolic process GO:1901564 151 0.026
ribose phosphate metabolic process GO:0019693 99 0.026
neuron projection development GO:0031175 187 0.026
sex differentiation GO:0007548 909 0.025
regulation of vulval development GO:0040028 248 0.025
organophosphate metabolic process GO:0019637 125 0.025
nervous system development GO:0007399 253 0.025
Fly
post embryonic organ development GO:0048569 336 0.024
actin cytoskeleton organization GO:0030036 184 0.024
defense response GO:0006952 296 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.024
positive regulation of developmental process GO:0051094 408 0.024
regulation of signaling GO:0023051 172 0.024
cytoskeleton organization GO:0007010 339 0.023
Fly
amine metabolic process GO:0009308 15 0.023
reproductive behavior GO:0019098 387 0.023
response to abiotic stimulus GO:0009628 152 0.023
Worm
synaptonemal complex organization GO:0070193 8 0.023
response to chemical GO:0042221 356 0.023
gene expression GO:0010467 412 0.022
Human Mouse Worm Fly
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.022
Worm
organic cyclic compound catabolic process GO:1901361 119 0.022
nucleoside phosphate metabolic process GO:0006753 108 0.022
organonitrogen compound catabolic process GO:1901565 90 0.022
regulation of cellular component organization GO:0051128 248 0.022
Fly
nucleoside triphosphate catabolic process GO:0009143 72 0.022
nucleoside metabolic process GO:0009116 99 0.022
negative regulation of multicellular organismal process GO:0051241 236 0.022
cell growth GO:0016049 44 0.021
Fly
regulation of molecular function GO:0065009 89 0.021
regulation of multicellular organismal development GO:2000026 317 0.020
purine containing compound metabolic process GO:0072521 95 0.020
purine nucleoside triphosphate metabolic process GO:0009144 87 0.020
immune response GO:0006955 192 0.020
ribosome biogenesis GO:0042254 4 0.020
innate immune response GO:0045087 190 0.020
localization of cell GO:0051674 313 0.019
posttranscriptional regulation of gene expression GO:0010608 166 0.019
Human Worm
phosphorus metabolic process GO:0006793 232 0.019
purine containing compound catabolic process GO:0072523 75 0.019
multi multicellular organism process GO:0044706 390 0.019
carbohydrate derivative catabolic process GO:1901136 82 0.019
protein modification by small protein conjugation or removal GO:0070647 40 0.018
generation of neurons GO:0048699 235 0.018
organic cyclic compound biosynthetic process GO:1901362 195 0.018
negative regulation of developmental process GO:0051093 227 0.018
regulation of gene expression GO:0010468 366 0.018
Human Worm
purine nucleoside metabolic process GO:0042278 92 0.018
cellular nitrogen compound biosynthetic process GO:0044271 192 0.018
dna metabolic process GO:0006259 74 0.018
Fly
defense response to bacterium GO:0042742 86 0.018
ribonucleoside metabolic process GO:0009119 98 0.018
hermaphrodite genitalia development GO:0040035 734 0.018
regulation of nematode larval development GO:0061062 260 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
cell migration GO:0016477 306 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
oviposition GO:0018991 364 0.017
positive regulation of cellular process GO:0048522 332 0.017
Human Worm
response to organic substance GO:0010033 131 0.017
ribonucleotide metabolic process GO:0009259 99 0.016
spermatogenesis GO:0007283 41 0.016
purine nucleotide metabolic process GO:0006163 95 0.016
negative regulation of signal transduction GO:0009968 60 0.016
nucleoside phosphate catabolic process GO:1901292 77 0.016
developmental maturation GO:0021700 26 0.016
multi organism behavior GO:0051705 389 0.016
cell proliferation GO:0008283 116 0.016
regulation of nitrogen compound metabolic process GO:0051171 222 0.016
gene silencing by rna GO:0031047 143 0.016
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.016
negative regulation of vulval development GO:0040027 206 0.015
carboxylic acid metabolic process GO:0019752 34 0.015
dna conformation change GO:0071103 11 0.015
Fly
positive regulation of rna metabolic process GO:0051254 103 0.015
organic substance transport GO:0071702 113 0.015
positive regulation of cell cycle GO:0045787 55 0.015
Human
regulation of cell communication GO:0010646 176 0.015
response to wounding GO:0009611 4 0.015
rna interference GO:0016246 137 0.015
biosynthetic process GO:0009058 323 0.015
Human Mouse Worm Fly
axon development GO:0061564 163 0.015
regulation of multi organism process GO:0043900 69 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
aromatic compound catabolic process GO:0019439 116 0.014
neuromuscular junction development GO:0007528 2 0.014
glycosyl compound metabolic process GO:1901657 100 0.014
molting cycle GO:0042303 281 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of response to stimulus GO:0048583 243 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
regulation of programmed cell death GO:0043067 50 0.013
neuron projection guidance GO:0097485 82 0.013
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
negative regulation of nematode larval development GO:0061064 208 0.013
axonogenesis GO:0007409 102 0.012
rna biosynthetic process GO:0032774 169 0.012
purine ribonucleotide metabolic process GO:0009150 95 0.012
rna localization GO:0006403 3 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
single organism catabolic process GO:0044712 129 0.012
purine ribonucleotide catabolic process GO:0009154 75 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 28 0.012
gene silencing GO:0016458 143 0.012
glycosyl compound catabolic process GO:1901658 79 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
negative regulation of cell communication GO:0010648 61 0.011
mating behavior GO:0007617 32 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
regulation of macromolecule biosynthetic process GO:0010556 189 0.011
Human Worm
regulation of protein metabolic process GO:0051246 81 0.011
Human Worm
negative regulation of signaling GO:0023057 61 0.011
modification dependent macromolecule catabolic process GO:0043632 32 0.011
cellular protein catabolic process GO:0044257 37 0.011
response to external biotic stimulus GO:0043207 101 0.011
ubiquitin dependent protein catabolic process GO:0006511 32 0.011
positive regulation of rna biosynthetic process GO:1902680 102 0.011
skeletal muscle organ development GO:0060538 3 0.011
rna metabolic process GO:0016070 228 0.011
Fly
muscle tissue development GO:0060537 1 0.011
protein metabolic process GO:0019538 422 0.011
Human Mouse Worm Fly
anterior posterior axis specification GO:0009948 17 0.011
multi organism reproductive behavior GO:0044705 387 0.011
regulation of protein stability GO:0031647 3 0.011
single organism intracellular transport GO:1902582 70 0.011
asymmetric protein localization GO:0008105 35 0.011
embryonic morphogenesis GO:0048598 152 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
aromatic compound biosynthetic process GO:0019438 192 0.011
chromosome segregation GO:0007059 180 0.011
Worm Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.010
Human Mouse Worm Fly
cellular macromolecule localization GO:0070727 75 0.010
cellular amino acid metabolic process GO:0006520 15 0.010
axon guidance GO:0007411 82 0.010
microtubule based process GO:0007017 182 0.010
Fly
regulation of cell differentiation GO:0045595 81 0.010
chromatin organization GO:0006325 32 0.010
Fly
mitotic nuclear division GO:0007067 89 0.010
Fly
organophosphate catabolic process GO:0046434 81 0.010

ife-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014