Caenorhabditis elegans

66 known processes

gex-2 (CELE_F56A11.1)

Protein GEX-2

gex-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.511
negative regulation of vulval development GO:0040027 206 0.445
regulation of vulval development GO:0040028 248 0.397
post embryonic organ development GO:0048569 336 0.364
negative regulation of developmental process GO:0051093 227 0.353
negative regulation of nematode larval development GO:0061064 208 0.333
organ development GO:0048513 1102 0.330
growth GO:0040007 562 0.273
single organism reproductive process GO:0044702 1196 0.259
reproductive system development GO:0061458 850 0.255
regulation of post embryonic development GO:0048580 260 0.213
development of primary sexual characteristics GO:0045137 840 0.211
vulval development GO:0040025 333 0.199
localization of cell GO:0051674 313 0.198
negative regulation of post embryonic development GO:0048581 208 0.195
regulation of developmental process GO:0050793 684 0.195
Fly
regulation of multicellular organismal process GO:0051239 726 0.189
cellular component morphogenesis GO:0032989 318 0.185
post embryonic development GO:0009791 2152 0.174
sex differentiation GO:0007548 909 0.159
embryo development GO:0009790 3052 0.159
multi organism reproductive process GO:0044703 867 0.156
genitalia development GO:0048806 741 0.149
determination of adult lifespan GO:0008340 812 0.148
regulation of nematode larval development GO:0061062 260 0.141
organelle organization GO:0006996 783 0.140
Fly
negative regulation of biological process GO:0048519 567 0.140
multicellular organism reproduction GO:0032504 819 0.139
reproductive structure development GO:0048608 850 0.138
locomotion GO:0040011 1634 0.138
oviposition GO:0018991 364 0.136
developmental process involved in reproduction GO:0003006 1165 0.131
cell projection organization GO:0030030 231 0.123
cell cycle process GO:0022402 482 0.122
negative regulation of multicellular organismal process GO:0051241 236 0.121
nucleobase containing compound metabolic process GO:0006139 406 0.121
single organism organelle organization GO:1902589 501 0.121
Fly
regulation of multicellular organismal development GO:2000026 317 0.116
regulation of cellular component organization GO:0051128 248 0.115
Fly
multicellular organismal reproductive process GO:0048609 815 0.115
transport GO:0006810 1093 0.112
Fly
behavior GO:0007610 527 0.110
mitotic nuclear division GO:0007067 89 0.106
anatomical structure formation involved in morphogenesis GO:0048646 250 0.103
Zebrafish
vesicle mediated transport GO:0016192 852 0.099
Fly
cell development GO:0048468 696 0.096
tissue morphogenesis GO:0048729 65 0.094
Zebrafish
neuron differentiation GO:0030182 217 0.093
cell motility GO:0048870 313 0.087
gonad development GO:0008406 840 0.086
establishment of localization GO:0051234 1171 0.084
Fly
aging GO:0007568 812 0.083
protein metabolic process GO:0019538 422 0.082
multi organism reproductive behavior GO:0044705 387 0.082
regulation of developmental growth GO:0048638 389 0.081
generation of neurons GO:0048699 235 0.081
positive regulation of developmental process GO:0051094 408 0.079
organelle fission GO:0048285 363 0.078
regulation of metabolic process GO:0019222 478 0.074
regulation of growth GO:0040008 409 0.074
reproductive behavior GO:0019098 387 0.073
regulation of nitrogen compound metabolic process GO:0051171 222 0.073
positive regulation of nucleotide catabolic process GO:0030813 28 0.071
positive regulation of multicellular organismal process GO:0051240 417 0.070
cell death GO:0008219 547 0.070
cell cycle GO:0007049 526 0.070
receptor mediated endocytosis GO:0006898 715 0.070
positive regulation of cellular process GO:0048522 332 0.069
macromolecule localization GO:0033036 771 0.068
single organism localization GO:1902578 518 0.067
Fly
negative regulation of cellular process GO:0048523 239 0.065
regulation of cell projection organization GO:0031344 38 0.065
developmental growth GO:0048589 412 0.064
cellular component movement GO:0006928 388 0.063
cell morphogenesis GO:0000902 163 0.061
lipid storage GO:0019915 565 0.061
axon development GO:0061564 163 0.060
maintenance of location GO:0051235 580 0.060
head development GO:0060322 1 0.060
ras protein signal transduction GO:0007265 31 0.059
lipid localization GO:0010876 573 0.057
gene expression GO:0010467 412 0.057
regulation of cellular metabolic process GO:0031323 305 0.057
sexual reproduction GO:0019953 546 0.056
multicellular organism growth GO:0035264 385 0.055
hermaphrodite genitalia development GO:0040035 734 0.055
multi multicellular organism process GO:0044706 390 0.055
neuron projection development GO:0031175 187 0.054
neuron development GO:0048666 199 0.053
positive regulation of growth GO:0045927 369 0.053
regulation of nuclear division GO:0051783 115 0.053
multi organism behavior GO:0051705 389 0.052
establishment of localization in cell GO:0051649 318 0.051
meiotic nuclear division GO:0007126 300 0.050
signaling GO:0023052 401 0.050
Fly
multicellular organismal reproductive behavior GO:0033057 384 0.049
positive regulation of multicellular organism growth GO:0040018 352 0.049
cellular biosynthetic process GO:0044249 315 0.049
mitotic cell cycle process GO:1903047 194 0.048
regulation of organelle organization GO:0033043 164 0.048
regulation of primary metabolic process GO:0080090 292 0.048
gamete generation GO:0007276 461 0.048
meiotic cell cycle GO:0051321 335 0.047
regulation of macromolecule metabolic process GO:0060255 421 0.046
cellular protein metabolic process GO:0044267 279 0.046
organic substance biosynthetic process GO:1901576 323 0.046
neuron recognition GO:0008038 83 0.046
cellular macromolecule biosynthetic process GO:0034645 247 0.046
small gtpase mediated signal transduction GO:0007264 32 0.045
macromolecular complex subunit organization GO:0043933 320 0.044
multicellular organismal aging GO:0010259 812 0.044
cell part morphogenesis GO:0032990 152 0.042
response to external stimulus GO:0009605 289 0.042
endocytosis GO:0006897 819 0.042
Fly
regulation of biological quality GO:0065008 741 0.041
Fly
cellular nitrogen compound catabolic process GO:0044270 119 0.041
neuron projection guidance GO:0097485 82 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.041
cell fate commitment GO:0045165 139 0.040
epithelial tube morphogenesis GO:0060562 1 0.040
carbohydrate derivative metabolic process GO:1901135 141 0.040
single organism signaling GO:0044700 401 0.040
Fly
nucleoside triphosphate catabolic process GO:0009143 72 0.040
male sex differentiation GO:0046661 86 0.039
regulation of multicellular organism growth GO:0040014 373 0.039
organonitrogen compound metabolic process GO:1901564 151 0.039
cellular macromolecular complex assembly GO:0034622 184 0.038
signal transduction GO:0007165 317 0.038
nucleic acid metabolic process GO:0090304 299 0.037
nervous system development GO:0007399 253 0.036
ribonucleoside triphosphate catabolic process GO:0009203 72 0.036
death GO:0016265 547 0.036
positive regulation of developmental growth GO:0048639 354 0.036
response to wounding GO:0009611 4 0.035
cell migration GO:0016477 306 0.035
apoptotic process GO:0006915 478 0.035
nucleoside triphosphate metabolic process GO:0009141 87 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.035
regulation of gene expression epigenetic GO:0040029 163 0.034
negative regulation of metabolic process GO:0009892 240 0.034
organic substance transport GO:0071702 113 0.034
axonal fasciculation GO:0007413 79 0.033
regulation of gene expression GO:0010468 366 0.033
regulation of biosynthetic process GO:0009889 189 0.033
single organism catabolic process GO:0044712 129 0.033
embryonic body morphogenesis GO:0010172 49 0.032
small molecule metabolic process GO:0044281 186 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.032
purine ribonucleoside metabolic process GO:0046128 92 0.032
regulation of cell proliferation GO:0042127 105 0.032
muscle structure development GO:0061061 191 0.032
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.031
regulation of localization GO:0032879 194 0.031
purine nucleoside metabolic process GO:0042278 92 0.031
regulation of rna metabolic process GO:0051252 173 0.031
actin filament based process GO:0030029 191 0.030
Fly
carbohydrate derivative catabolic process GO:1901136 82 0.030
ribonucleotide catabolic process GO:0009261 75 0.030
taxis GO:0042330 128 0.030
inductive cell migration GO:0040039 145 0.030
posttranscriptional gene silencing GO:0016441 143 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.029
organ morphogenesis GO:0009887 67 0.029
Zebrafish Fly
purine nucleoside catabolic process GO:0006152 75 0.029
macromolecule biosynthetic process GO:0009059 250 0.029
programmed cell death GO:0012501 500 0.029
membrane organization GO:0061024 135 0.029
biosynthetic process GO:0009058 323 0.028
cell recognition GO:0008037 85 0.028
germ cell development GO:0007281 351 0.028
body morphogenesis GO:0010171 620 0.028
cell projection morphogenesis GO:0048858 148 0.028
cytoskeleton organization GO:0007010 339 0.027
Fly
positive regulation of cell projection organization GO:0031346 4 0.027
regulation of meiotic cell cycle GO:0051445 136 0.027
negative regulation of gene expression GO:0010629 217 0.027
dosage compensation by hypoactivation of x chromosome GO:0042464 11 0.026
ribonucleoside catabolic process GO:0042454 77 0.026
organonitrogen compound catabolic process GO:1901565 90 0.026
secretion by cell GO:0032940 138 0.026
negative regulation of macromolecule metabolic process GO:0010605 229 0.026
regulation of axonogenesis GO:0050770 24 0.026
negative regulation of biosynthetic process GO:0009890 65 0.026
organic cyclic compound catabolic process GO:1901361 119 0.026
regulation of cell differentiation GO:0045595 81 0.025
epithelium development GO:0060429 68 0.025
organic substance catabolic process GO:1901575 294 0.024
regulation of neuron projection development GO:0010975 31 0.024
sister chromatid segregation GO:0000819 46 0.024
male anatomical structure morphogenesis GO:0090598 78 0.024
response to chemical GO:0042221 356 0.024
regulation of locomotion GO:0040012 161 0.024
regulation of macromolecule biosynthetic process GO:0010556 189 0.023
positive regulation of neurogenesis GO:0050769 4 0.023
single organism transport GO:0044765 447 0.023
Fly
striated muscle myosin thick filament assembly GO:0071688 138 0.023
phagocytosis engulfment GO:0006911 98 0.023
purine nucleoside triphosphate metabolic process GO:0009144 87 0.023
nucleoside phosphate metabolic process GO:0006753 108 0.023
regulation of cell communication GO:0010646 176 0.023
organophosphate metabolic process GO:0019637 125 0.023
fertilization GO:0009566 63 0.023
female gamete generation GO:0007292 254 0.023
cellular localization GO:0051641 360 0.023
intracellular receptor signaling pathway GO:0030522 2 0.023
positive regulation of macromolecule metabolic process GO:0010604 149 0.022
organophosphate catabolic process GO:0046434 81 0.022
posttranscriptional regulation of gene expression GO:0010608 166 0.022
nucleobase containing small molecule metabolic process GO:0055086 115 0.022
axonogenesis GO:0007409 102 0.022
cellular response to stress GO:0033554 162 0.021
aromatic compound biosynthetic process GO:0019438 192 0.021
establishment of spindle localization GO:0051293 51 0.021
neurogenesis GO:0022008 236 0.021
nucleoside metabolic process GO:0009116 99 0.021
gene silencing GO:0016458 143 0.021
ribose phosphate metabolic process GO:0019693 99 0.021
meiotic chromosome segregation GO:0045132 139 0.021
embryonic morphogenesis GO:0048598 152 0.021
muscle cell differentiation GO:0042692 171 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.021
nucleic acid templated transcription GO:0097659 169 0.021
negative regulation of gene expression epigenetic GO:0045814 2 0.020
nematode male tail tip morphogenesis GO:0045138 77 0.020
regulation of small gtpase mediated signal transduction GO:0051056 41 0.020
macromolecule catabolic process GO:0009057 202 0.020
regulation of neuron differentiation GO:0045664 40 0.020
sensory organ morphogenesis GO:0090596 2 0.020
Zebrafish Fly
catabolic process GO:0009056 318 0.020
synaptic transmission GO:0007268 106 0.020
Fly
myosin filament organization GO:0031033 138 0.020
collagen and cuticulin based cuticle development GO:0040002 99 0.019
regulation of ras protein signal transduction GO:0046578 41 0.019
cell proliferation GO:0008283 116 0.019
ribonucleoside metabolic process GO:0009119 98 0.019
rna metabolic process GO:0016070 228 0.019
regulation of synapse assembly GO:0051963 2 0.019
mrna splice site selection GO:0006376 1 0.019
pre mirna processing GO:0031054 3 0.019
glycosyl compound catabolic process GO:1901658 79 0.019
transcription dna templated GO:0006351 168 0.019
oogenesis GO:0048477 229 0.018
regulation of molecular function GO:0065009 89 0.018
apoptotic cell clearance GO:0043277 111 0.018
organelle assembly GO:0070925 214 0.018
regulation of chromosome segregation GO:0051983 20 0.018
actomyosin structure organization GO:0031032 154 0.018
regeneration GO:0031099 4 0.018
ribonucleoprotein complex assembly GO:0022618 4 0.018
cell division GO:0051301 262 0.018
posttranscriptional gene silencing by rna GO:0035194 143 0.018
actin cytoskeleton organization GO:0030036 184 0.018
Fly
purine ribonucleotide metabolic process GO:0009150 95 0.018
nuclear migration GO:0007097 54 0.018
regulation of cell cycle process GO:0010564 145 0.018
nucleobase containing compound biosynthetic process GO:0034654 184 0.017
regulation of hydrolase activity GO:0051336 45 0.017
positive regulation of metabolic process GO:0009893 187 0.017
purine ribonucleotide catabolic process GO:0009154 75 0.017
heterocycle catabolic process GO:0046700 119 0.017
regulation of catalytic activity GO:0050790 78 0.017
aromatic compound catabolic process GO:0019439 116 0.017
cellular protein complex assembly GO:0043623 178 0.017
striated muscle cell differentiation GO:0051146 158 0.017
nucleotide catabolic process GO:0009166 77 0.017
purine nucleoside triphosphate catabolic process GO:0009146 72 0.017
chemotaxis GO:0006935 120 0.017
cellular component assembly GO:0022607 293 0.017
Mouse Fly
regulation of meiosis GO:0040020 94 0.016
cellular catabolic process GO:0044248 199 0.016
positive regulation of cellular catabolic process GO:0031331 35 0.016
rna biosynthetic process GO:0032774 169 0.016
myosin filament assembly GO:0031034 138 0.016
establishment of organelle localization GO:0051656 123 0.016
cellular nitrogen compound biosynthetic process GO:0044271 192 0.016
ribonucleotide metabolic process GO:0009259 99 0.016
digestive tract development GO:0048565 122 0.016
memory GO:0007613 3 0.016
axon guidance GO:0007411 82 0.016
positive regulation of cell migration GO:0030335 3 0.016
endosomal transport GO:0016197 26 0.016
purine nucleotide catabolic process GO:0006195 75 0.016
regulation of catabolic process GO:0009894 57 0.015
negative regulation of cellular metabolic process GO:0031324 95 0.015
regulation of phosphorus metabolic process GO:0051174 81 0.015
muscle cell development GO:0055001 158 0.015
pronuclear migration GO:0035046 51 0.015
regulation of cellular protein metabolic process GO:0032268 75 0.015
gene silencing by rna GO:0031047 143 0.015
dendrite development GO:0016358 42 0.015
sex determination GO:0007530 60 0.015
positive regulation of protein metabolic process GO:0051247 45 0.015
tube development GO:0035295 126 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
negative regulation of axon extension GO:0030517 2 0.015
chromosome segregation GO:0007059 180 0.015
mitotic sister chromatid segregation GO:0000070 38 0.014
translational initiation GO:0006413 2 0.014
cuticle development GO:0042335 100 0.014
molting cycle GO:0042303 281 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
organelle localization GO:0051640 127 0.014
engulfment of apoptotic cell GO:0043652 94 0.014
purine nucleotide metabolic process GO:0006163 95 0.014
neuron projection extension involved in neuron projection guidance GO:1902284 13 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 29 0.014
rho protein signal transduction GO:0007266 2 0.014
heterocycle biosynthetic process GO:0018130 187 0.014
rna interference GO:0016246 137 0.014
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
system process GO:0003008 136 0.014
striated muscle cell development GO:0055002 157 0.014
phosphorus metabolic process GO:0006793 232 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 28 0.014
regulation of gtpase activity GO:0043087 30 0.014
gtp metabolic process GO:0046039 46 0.014
regulation of nervous system development GO:0051960 41 0.014
oxoacid metabolic process GO:0043436 47 0.013
neuromuscular junction development GO:0007528 2 0.013
protein complex subunit organization GO:0071822 280 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
regulation of signal transduction GO:0009966 135 0.013
neuron projection morphogenesis GO:0048812 114 0.013
positive regulation of locomotion GO:0040017 42 0.013
microtubule based process GO:0007017 182 0.013
intracellular signal transduction GO:0035556 96 0.013
regulation of translation GO:0006417 19 0.013
nucleotide metabolic process GO:0009117 108 0.013
regulation of cell cycle GO:0051726 194 0.013
digestive system development GO:0055123 122 0.013
protein catabolic process GO:0030163 162 0.013
regulation of response to stimulus GO:0048583 243 0.013
cellular response to unfolded protein GO:0034620 71 0.013
nucleobase containing compound catabolic process GO:0034655 114 0.013
membrane invagination GO:0010324 98 0.013
regulation of ras gtpase activity GO:0032318 21 0.013
chromatin remodeling GO:0006338 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 35 0.012
phosphate containing compound metabolic process GO:0006796 232 0.012
purine containing compound catabolic process GO:0072523 75 0.012
nucleoside phosphate catabolic process GO:1901292 77 0.012
regulation of behavior GO:0050795 97 0.012
regulation of endocytosis GO:0030100 25 0.012
muscle tissue development GO:0060537 1 0.012
meiotic cell cycle process GO:1903046 170 0.012
positive regulation of molecular function GO:0044093 61 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
establishment of nucleus localization GO:0040023 55 0.012
dna templated transcription elongation GO:0006354 1 0.012
positive regulation of cellular metabolic process GO:0031325 178 0.012
regulation of nucleic acid templated transcription GO:1903506 165 0.012
macromolecular complex assembly GO:0065003 193 0.011
positive regulation of neuron projection development GO:0010976 4 0.011
response to unfolded protein GO:0006986 71 0.011
purine containing compound metabolic process GO:0072521 95 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
protein modification process GO:0036211 207 0.011
macromolecule modification GO:0043412 218 0.011
cellular component biogenesis GO:0044085 297 0.011
Mouse Fly
tissue development GO:0009888 112 0.010
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 195 0.010
regulation of cellular biosynthetic process GO:0031326 189 0.010
regulation of cell division GO:0051302 142 0.010
negative regulation of nucleic acid templated transcription GO:1903507 53 0.010
response to heat GO:0009408 50 0.010
cellular response to chemical stimulus GO:0070887 129 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
phagocytosis GO:0006909 115 0.010
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.010

gex-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
musculoskeletal system disease DOID:17 0 0.052
congenital muscular dystrophy DOID:0050557 0 0.052
muscular dystrophy DOID:9884 0 0.052
muscle tissue disease DOID:66 0 0.052
muscular disease DOID:0080000 0 0.052
myopathy DOID:423 0 0.052
nervous system disease DOID:863 0 0.019
neuropathy DOID:870 0 0.019
charcot marie tooth disease DOID:10595 0 0.019
neuromuscular disease DOID:440 0 0.019
charcot marie tooth disease type 2 DOID:0050539 0 0.019
disease of metabolism DOID:0014667 0 0.014