Caenorhabditis elegans

4 known processes

unc-1 (CELE_K03E6.5)

Protein UNC-1

unc-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell projection morphogenesis GO:0048858 148 0.391
embryo development ending in birth or egg hatching GO:0009792 2992 0.389
Worm
locomotion GO:0040011 1634 0.314
cell cycle GO:0007049 526 0.290
single organism signaling GO:0044700 401 0.277
organelle organization GO:0006996 783 0.249
cell morphogenesis involved in differentiation GO:0000904 112 0.228
embryo development GO:0009790 3052 0.200
Worm
behavior GO:0007610 527 0.198
Worm
establishment of localization GO:0051234 1171 0.194
Worm
taxis GO:0042330 128 0.191
post embryonic development GO:0009791 2152 0.188
Worm
phosphate containing compound metabolic process GO:0006796 232 0.155
regulation of response to stimulus GO:0048583 243 0.132
cell cell signaling GO:0007267 118 0.128
regulation of multicellular organismal process GO:0051239 726 0.125
death GO:0016265 547 0.124
neurogenesis GO:0022008 236 0.122
regulation of signaling GO:0023051 172 0.108
cytoskeleton organization GO:0007010 339 0.107
chemotaxis GO:0006935 120 0.103
single organism transport GO:0044765 447 0.102
synaptic transmission GO:0007268 106 0.100
pronuclear migration GO:0035046 51 0.100
single organism organelle organization GO:1902589 501 0.097
regulation of biological quality GO:0065008 741 0.097
positive regulation of multicellular organismal process GO:0051240 417 0.092
regulation of organelle organization GO:0033043 164 0.088
regulation of signal transduction GO:0009966 135 0.084
vesicle mediated transport GO:0016192 852 0.083
regulation of atp catabolic process GO:1903289 3 0.082
negative regulation of transporter activity GO:0032410 3 0.074
endocytosis GO:0006897 819 0.074
regulation of phosphate metabolic process GO:0019220 81 0.074
actin cytoskeleton organization GO:0030036 184 0.074
multicellular organismal reproductive process GO:0048609 815 0.073
cellular component morphogenesis GO:0032989 318 0.072
protein metabolic process GO:0019538 422 0.070
Worm
growth GO:0040007 562 0.069
Worm
neuron projection morphogenesis GO:0048812 114 0.068
negative regulation of cellular process GO:0048523 239 0.068
cell adhesion GO:0007155 21 0.067
cell part morphogenesis GO:0032990 152 0.065
transport GO:0006810 1093 0.065
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.064
positive regulation of metabolic process GO:0009893 187 0.063
cell projection organization GO:0030030 231 0.062
establishment of vesicle localization GO:0051650 23 0.062
negative regulation of biological process GO:0048519 567 0.061
regulation of cell communication GO:0010646 176 0.061
cell development GO:0048468 696 0.060
regulation of phosphorus metabolic process GO:0051174 81 0.060
regulation of multi organism process GO:0043900 69 0.059
positive regulation of multicellular organism growth GO:0040018 352 0.059
gonad development GO:0008406 840 0.059
developmental process involved in reproduction GO:0003006 1165 0.058
sensory organ morphogenesis GO:0090596 2 0.057
multicellular organismal aging GO:0010259 812 0.057
synaptic vesicle endocytosis GO:0048488 3 0.056
organelle fission GO:0048285 363 0.055
negative regulation of cation channel activity GO:2001258 2 0.054
multicellular organism growth GO:0035264 385 0.053
cell morphogenesis GO:0000902 163 0.052
single organism behavior GO:0044708 83 0.052
Worm
positive regulation of developmental process GO:0051094 408 0.051
regulation of growth GO:0040008 409 0.051
positive regulation of cellular metabolic process GO:0031325 178 0.051
establishment of organelle localization GO:0051656 123 0.050
multicellular organism reproduction GO:0032504 819 0.048
positive regulation of growth GO:0045927 369 0.048
regulation of cellular component organization GO:0051128 248 0.048
regulation of developmental process GO:0050793 684 0.048
cellular component movement GO:0006928 388 0.048
regulation of developmental growth GO:0048638 389 0.048
determination of adult lifespan GO:0008340 812 0.047
meiotic cell cycle GO:0051321 335 0.047
body morphogenesis GO:0010171 620 0.047
lipid localization GO:0010876 573 0.047
macromolecule localization GO:0033036 771 0.046
Worm
organelle assembly GO:0070925 214 0.046
lipid storage GO:0019915 565 0.046
multi organism behavior GO:0051705 389 0.045
cell death GO:0008219 547 0.044
aging GO:0007568 812 0.043
developmental growth GO:0048589 412 0.043
neurotransmitter transport GO:0006836 32 0.043
meiotic nuclear division GO:0007126 300 0.043
signal transduction GO:0007165 317 0.042
actin filament based process GO:0030029 191 0.042
maintenance of location GO:0051235 580 0.041
ion transport GO:0006811 113 0.041
regulation of multicellular organism growth GO:0040014 373 0.041
positive regulation of signaling GO:0023056 66 0.040
neuron differentiation GO:0030182 217 0.040
positive regulation of cellular process GO:0048522 332 0.040
programmed cell death GO:0012501 500 0.039
positive regulation of developmental growth GO:0048639 354 0.038
epithelial tube morphogenesis GO:0060562 1 0.038
single organism localization GO:1902578 518 0.038
reproductive structure development GO:0048608 850 0.038
development of primary sexual characteristics GO:0045137 840 0.037
muscle cell development GO:0055001 158 0.037
regulation of synaptic plasticity GO:0048167 1 0.036
cell migration GO:0016477 306 0.035
cell growth GO:0016049 44 0.034
embryonic morphogenesis GO:0048598 152 0.034
synaptic vesicle recycling GO:0036465 3 0.034
reproductive system development GO:0061458 850 0.033
myofibril assembly GO:0030239 154 0.033
synaptic vesicle transport GO:0048489 21 0.032
genitalia development GO:0048806 741 0.032
signaling GO:0023052 401 0.032
negative regulation of ion transmembrane transport GO:0034766 3 0.031
multi organism reproductive process GO:0044703 867 0.031
macromolecular complex subunit organization GO:0043933 320 0.031
cell cycle process GO:0022402 482 0.031
single organism reproductive process GO:0044702 1196 0.031
axon guidance GO:0007411 82 0.030
cellular localization GO:0051641 360 0.030
cellular component assembly GO:0022607 293 0.030
cellular biosynthetic process GO:0044249 315 0.030
response to external stimulus GO:0009605 289 0.030
Worm
positive regulation of signal transduction GO:0009967 40 0.029
establishment of nucleus localization GO:0040023 55 0.028
regulation of molecular function GO:0065009 89 0.028
nervous system development GO:0007399 253 0.028
regulation of cellular metabolic process GO:0031323 305 0.027
inactivation of mapkkk activity GO:0051390 2 0.027
actomyosin structure organization GO:0031032 154 0.027
generation of neurons GO:0048699 235 0.027
muscle cell differentiation GO:0042692 171 0.027
regulation of multicellular organismal development GO:2000026 317 0.027
microtubule based process GO:0007017 182 0.027
regulation of localization GO:0032879 194 0.026
reproductive behavior GO:0019098 387 0.026
muscle structure development GO:0061061 191 0.026
cell division GO:0051301 262 0.026
apoptotic process GO:0006915 478 0.026
cell matrix adhesion GO:0007160 1 0.025
catabolic process GO:0009056 318 0.025
Worm
regulation of atpase activity GO:0043462 3 0.025
positive regulation of cell communication GO:0010647 69 0.024
nucleus localization GO:0051647 55 0.024
peptidyl serine phosphorylation GO:0018105 20 0.024
regulation of locomotion GO:0040012 161 0.024
regulation of phosphorylation GO:0042325 45 0.024
protein modification process GO:0036211 207 0.024
multi multicellular organism process GO:0044706 390 0.023
ion transmembrane transport GO:0034220 91 0.023
positive regulation of cell migration GO:0030335 3 0.023
defense response GO:0006952 296 0.023
regulation of cell cycle GO:0051726 194 0.023
negative regulation of transmembrane transport GO:0034763 3 0.023
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.023
regulation of metabolic process GO:0019222 478 0.022
macromolecule modification GO:0043412 218 0.022
membrane organization GO:0061024 135 0.022
regulation of neurotransmitter levels GO:0001505 36 0.022
protein complex biogenesis GO:0070271 186 0.022
positive regulation of intracellular signal transduction GO:1902533 24 0.022
fertilization GO:0009566 63 0.022
regulation of cell death GO:0010941 65 0.022
mitotic cell cycle process GO:1903047 194 0.022
germ cell development GO:0007281 351 0.022
monovalent inorganic cation transport GO:0015672 33 0.021
peptidyl serine modification GO:0018209 20 0.021
cell motility GO:0048870 313 0.021
phosphorus metabolic process GO:0006793 232 0.021
intracellular signal transduction GO:0035556 96 0.021
cell substrate adhesion GO:0031589 1 0.021
organelle localization GO:0051640 127 0.021
receptor mediated endocytosis GO:0006898 715 0.021
cell cycle phase transition GO:0044770 19 0.021
negative regulation of multicellular organismal process GO:0051241 236 0.021
localization of cell GO:0051674 313 0.021
establishment of localization in cell GO:0051649 318 0.021
cell type specific apoptotic process GO:0097285 4 0.021
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.020
cellular component assembly involved in morphogenesis GO:0010927 183 0.020
epithelial cell proliferation GO:0050673 1 0.020
oocyte axis specification GO:0007309 2 0.020
positive regulation of rna metabolic process GO:0051254 103 0.020
sexual reproduction GO:0019953 546 0.020
striated muscle cell differentiation GO:0051146 158 0.020
signal transduction by phosphorylation GO:0023014 31 0.020
response to chemical GO:0042221 356 0.020
regulation of apoptotic signaling pathway GO:2001233 1 0.020
cellular protein complex assembly GO:0043623 178 0.020
lipid metabolic process GO:0006629 77 0.019
cellular macromolecular complex assembly GO:0034622 184 0.019
sex differentiation GO:0007548 909 0.019
lamellipodium assembly GO:0030032 2 0.019
negative regulation of cell cycle GO:0045786 53 0.018
eating behavior GO:0042755 59 0.018
muscle system process GO:0003012 43 0.018
response to abiotic stimulus GO:0009628 152 0.018
Worm
feeding behavior GO:0007631 70 0.018
learning or memory GO:0007611 27 0.018
protein complex subunit organization GO:0071822 280 0.018
establishment of protein localization to membrane GO:0090150 3 0.018
multi organism reproductive behavior GO:0044705 387 0.018
single organism membrane fusion GO:0044801 13 0.017
oviposition GO:0018991 364 0.017
regulation of nitrogen compound metabolic process GO:0051171 222 0.017
regulation of behavior GO:0050795 97 0.017
organ development GO:0048513 1102 0.017
regulation of cell proliferation GO:0042127 105 0.017
multicellular organismal reproductive behavior GO:0033057 384 0.017
cation transmembrane transport GO:0098655 59 0.017
intracellular transport GO:0046907 77 0.017
biological adhesion GO:0022610 21 0.017
cellular protein modification process GO:0006464 207 0.017
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
cellular protein metabolic process GO:0044267 279 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.017
detection of external stimulus GO:0009581 4 0.017
mitotic nuclear division GO:0007067 89 0.016
vesicle localization GO:0051648 24 0.016
regulation of anatomical structure size GO:0090066 46 0.016
regulation of exocytosis GO:0017157 1 0.016
macromolecular complex assembly GO:0065003 193 0.016
tissue development GO:0009888 112 0.016
muscle organ morphogenesis GO:0048644 4 0.016
response to wounding GO:0009611 4 0.016
cellular component biogenesis GO:0044085 297 0.016
organic substance catabolic process GO:1901575 294 0.016
Worm
axon development GO:0061564 163 0.016
axonogenesis GO:0007409 102 0.016
positive regulation of response to stimulus GO:0048584 55 0.015
neuron development GO:0048666 199 0.015
regulation of macromolecule metabolic process GO:0060255 421 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.015
negative regulation of cell morphogenesis involved in differentiation GO:0010771 2 0.015
negative regulation of cell communication GO:0010648 61 0.015
regulation of cation channel activity GO:2001257 3 0.015
hermaphrodite genitalia development GO:0040035 734 0.015
integrin mediated signaling pathway GO:0007229 1 0.014
cell fate commitment GO:0045165 139 0.014
striated muscle cell development GO:0055002 157 0.014
macromolecule catabolic process GO:0009057 202 0.014
Worm
positive regulation of intracellular transport GO:0032388 2 0.014
gamete generation GO:0007276 461 0.014
anatomical structure homeostasis GO:0060249 11 0.014
regulation of protein targeting GO:1903533 3 0.014
positive regulation of molecular function GO:0044093 61 0.014
regulation of cellular biosynthetic process GO:0031326 189 0.014
muscle cell cellular homeostasis GO:0046716 5 0.014
regulation of filopodium assembly GO:0051489 2 0.014
transmembrane transport GO:0055085 110 0.014
positive regulation of gene expression GO:0010628 112 0.014
single organism intracellular transport GO:1902582 70 0.013
regulation of intracellular signal transduction GO:1902531 77 0.013
head development GO:0060322 1 0.013
neuron neuron synaptic transmission GO:0007270 22 0.013
negative regulation of protein metabolic process GO:0051248 27 0.013
organelle fusion GO:0048284 8 0.013
inductive cell migration GO:0040039 145 0.013
single fertilization GO:0007338 61 0.013
positive regulation of cellular component organization GO:0051130 34 0.013
positive regulation of phosphate metabolic process GO:0045937 56 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
response to biotic stimulus GO:0009607 101 0.013
regulation of programmed cell death GO:0043067 50 0.013
membrane fusion GO:0061025 16 0.013
regulation of neuromuscular synaptic transmission GO:1900073 1 0.013
embryonic body morphogenesis GO:0010172 49 0.012
meiotic cell cycle process GO:1903046 170 0.012
oxoacid metabolic process GO:0043436 47 0.012
regulation of transport GO:0051049 91 0.012
regulation of cell cycle process GO:0010564 145 0.012
positive regulation of cell projection organization GO:0031346 4 0.012
regulation of lamellipodium organization GO:1902743 1 0.012
striated muscle myosin thick filament assembly GO:0071688 138 0.012
regulation of catalytic activity GO:0050790 78 0.012
negative regulation of neurogenesis GO:0050768 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
positive regulation of protein transport GO:0051222 4 0.012
homeostatic process GO:0042592 51 0.012
myosin filament organization GO:0031033 138 0.012
myosin filament assembly GO:0031034 138 0.012
posttranscriptional regulation of gene expression GO:0010608 166 0.012
organic substance transport GO:0071702 113 0.012
oocyte construction GO:0007308 2 0.012
anatomical structure formation involved in morphogenesis GO:0048646 250 0.012
system process GO:0003008 136 0.012
vesicle organization GO:0016050 15 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
positive regulation of phosphorylation GO:0042327 27 0.011
detection of abiotic stimulus GO:0009582 4 0.011
sex determination GO:0007530 60 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.011
pharyngeal pumping GO:0043050 58 0.011
negative regulation of signaling GO:0023057 61 0.011
regulation of gene expression GO:0010468 366 0.011
lamellipodium organization GO:0097581 2 0.011
neuron projection guidance GO:0097485 82 0.011
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
nucleobase containing compound metabolic process GO:0006139 406 0.011
regulation of system process GO:0044057 27 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
regulation of primary metabolic process GO:0080090 292 0.011
small molecule metabolic process GO:0044281 186 0.011
cell surface receptor signaling pathway GO:0007166 149 0.011
nuclear migration GO:0007097 54 0.010
positive regulation of cell death GO:0010942 38 0.010
negative regulation of gene expression GO:0010629 217 0.010
response to external biotic stimulus GO:0043207 101 0.010
water homeostasis GO:0030104 5 0.010
cellular catabolic process GO:0044248 199 0.010
cation transport GO:0006812 78 0.010
negative regulation of developmental process GO:0051093 227 0.010
muscle tissue development GO:0060537 1 0.010

unc-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
intrinsic cardiomyopathy DOID:0060036 0 0.032
disease of anatomical entity DOID:7 0 0.032
cardiomyopathy DOID:0050700 0 0.032
musculoskeletal system disease DOID:17 0 0.032
muscle tissue disease DOID:66 0 0.032
cardiovascular system disease DOID:1287 0 0.032
myopathy DOID:423 0 0.032
heart disease DOID:114 0 0.032
hypertrophic cardiomyopathy DOID:11984 0 0.032
muscular disease DOID:0080000 0 0.032