Caenorhabditis elegans

21 known processes

pbs-1 (CELE_K08D12.1)

Protein PBS-1

pbs-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.432
cellular catabolic process GO:0044248 199 0.426
Yeast
embryo development ending in birth or egg hatching GO:0009792 2992 0.394
organic substance catabolic process GO:1901575 294 0.376
Yeast
multicellular organismal reproductive process GO:0048609 815 0.364
catabolic process GO:0009056 318 0.363
Yeast
pronuclear migration GO:0035046 51 0.350
death GO:0016265 547 0.335
post embryonic development GO:0009791 2152 0.328
mitotic spindle organization GO:0007052 81 0.286
organophosphate metabolic process GO:0019637 125 0.256
modification dependent protein catabolic process GO:0019941 32 0.237
Yeast
cellular protein catabolic process GO:0044257 37 0.237
Yeast
multicellular organism reproduction GO:0032504 819 0.234
single fertilization GO:0007338 61 0.232
locomotion GO:0040011 1634 0.230
transport GO:0006810 1093 0.223
macromolecule catabolic process GO:0009057 202 0.220
Yeast
programmed cell death GO:0012501 500 0.217
sexual reproduction GO:0019953 546 0.217
single organism reproductive process GO:0044702 1196 0.215
mitotic cell cycle process GO:1903047 194 0.207
gamete generation GO:0007276 461 0.200
apoptotic process GO:0006915 478 0.185
organelle organization GO:0006996 783 0.185
ubiquitin dependent protein catabolic process GO:0006511 32 0.184
Yeast
determination of adult lifespan GO:0008340 812 0.178
negative regulation of vulval development GO:0040027 206 0.176
multi organism reproductive process GO:0044703 867 0.173
regulation of nematode larval development GO:0061062 260 0.161
organonitrogen compound metabolic process GO:1901564 151 0.155
nucleotide metabolic process GO:0009117 108 0.155
cellular component movement GO:0006928 388 0.153
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.152
Yeast
small molecule metabolic process GO:0044281 186 0.144
protein catabolic process GO:0030163 162 0.140
Yeast
genitalia development GO:0048806 741 0.139
molting cycle GO:0042303 281 0.138
single organism transport GO:0044765 447 0.130
gonad development GO:0008406 840 0.122
proteasome assembly GO:0043248 1 0.121
multicellular organismal aging GO:0010259 812 0.119
development of primary sexual characteristics GO:0045137 840 0.115
purine ribonucleoside catabolic process GO:0046130 75 0.114
cellular protein metabolic process GO:0044267 279 0.114
Yeast
proteasomal protein catabolic process GO:0010498 20 0.112
Yeast
establishment of localization GO:0051234 1171 0.112
regulation of cellular metabolic process GO:0031323 305 0.111
single organism organelle organization GO:1902589 501 0.110
phosphorus metabolic process GO:0006793 232 0.108
regulation of gene expression GO:0010468 366 0.106
aging GO:0007568 812 0.103
cellular nitrogen compound catabolic process GO:0044270 119 0.103
regulation of multicellular organism growth GO:0040014 373 0.100
organ development GO:0048513 1102 0.099
cell motility GO:0048870 313 0.098
modification dependent macromolecule catabolic process GO:0043632 32 0.096
Yeast
proteolysis GO:0006508 61 0.096
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.095
Yeast
cell cycle GO:0007049 526 0.094
protein metabolic process GO:0019538 422 0.093
Yeast
developmental process involved in reproduction GO:0003006 1165 0.092
nucleobase containing compound catabolic process GO:0034655 114 0.091
localization of cell GO:0051674 313 0.091
single organism localization GO:1902578 518 0.090
regulation of nucleic acid templated transcription GO:1903506 165 0.089
female gamete generation GO:0007292 254 0.089
vesicle mediated transport GO:0016192 852 0.087
spindle organization GO:0007051 92 0.087
cell death GO:0008219 547 0.087
endocytosis GO:0006897 819 0.086
hermaphrodite genitalia development GO:0040035 734 0.085
macromolecule localization GO:0033036 771 0.085
biosynthetic process GO:0009058 323 0.084
nucleobase containing compound metabolic process GO:0006139 406 0.084
nucleoside phosphate metabolic process GO:0006753 108 0.083
regulation of vulval development GO:0040028 248 0.083
positive regulation of cellular process GO:0048522 332 0.081
nervous system development GO:0007399 253 0.080
vulval development GO:0040025 333 0.080
regulation of developmental process GO:0050793 684 0.077
negative regulation of nematode larval development GO:0061064 208 0.077
developmental growth GO:0048589 412 0.075
post embryonic organ development GO:0048569 336 0.075
establishment of localization in cell GO:0051649 318 0.074
regulation of biological quality GO:0065008 741 0.073
behavior GO:0007610 527 0.073
phosphate containing compound metabolic process GO:0006796 232 0.073
aromatic compound catabolic process GO:0019439 116 0.073
purine nucleotide catabolic process GO:0006195 75 0.071
regulation of metabolic process GO:0019222 478 0.071
nucleobase containing compound biosynthetic process GO:0034654 184 0.071
nuclear migration GO:0007097 54 0.071
cellular macromolecule catabolic process GO:0044265 73 0.071
Yeast
nucleoside triphosphate metabolic process GO:0009141 87 0.071
lipid localization GO:0010876 573 0.070
cellular component biogenesis GO:0044085 297 0.068
growth GO:0040007 562 0.068
posttranscriptional regulation of gene expression GO:0010608 166 0.066
maintenance of location GO:0051235 580 0.066
carbohydrate derivative metabolic process GO:1901135 141 0.065
carbohydrate derivative catabolic process GO:1901136 82 0.065
nucleic acid templated transcription GO:0097659 169 0.065
secretion GO:0046903 147 0.065
macromolecule modification GO:0043412 218 0.064
ribonucleoside catabolic process GO:0042454 77 0.063
mitotic nuclear division GO:0007067 89 0.063
organophosphate catabolic process GO:0046434 81 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.062
regulation of post embryonic development GO:0048580 260 0.061
nucleoside catabolic process GO:0009164 78 0.060
cytoskeleton organization GO:0007010 339 0.060
regulation of macromolecule metabolic process GO:0060255 421 0.059
regulation of cellular biosynthetic process GO:0031326 189 0.059
nucleoside phosphate catabolic process GO:1901292 77 0.059
lipid storage GO:0019915 565 0.059
regulation of cellular component organization GO:0051128 248 0.058
purine nucleoside triphosphate catabolic process GO:0009146 72 0.057
positive regulation of multicellular organismal process GO:0051240 417 0.057
glycosyl compound metabolic process GO:1901657 100 0.057
multi organism reproductive behavior GO:0044705 387 0.057
multicellular organismal reproductive behavior GO:0033057 384 0.057
rna metabolic process GO:0016070 228 0.057
cell migration GO:0016477 306 0.056
response to external stimulus GO:0009605 289 0.056
protein complex biogenesis GO:0070271 186 0.055
regulation of multicellular organismal process GO:0051239 726 0.055
microtubule based process GO:0007017 182 0.055
reproductive structure development GO:0048608 850 0.054
heterocycle biosynthetic process GO:0018130 187 0.054
organonitrogen compound catabolic process GO:1901565 90 0.054
transcription from rna polymerase ii promoter GO:0006366 149 0.054
multicellular organism growth GO:0035264 385 0.054
negative regulation of biological process GO:0048519 567 0.053
body morphogenesis GO:0010171 620 0.053
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.053
ribose phosphate metabolic process GO:0019693 99 0.052
ribonucleoside triphosphate metabolic process GO:0009199 87 0.052
positive regulation of growth GO:0045927 369 0.052
negative regulation of developmental process GO:0051093 227 0.051
cellular protein modification process GO:0006464 207 0.051
regulation of protein metabolic process GO:0051246 81 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.051
cellular component assembly GO:0022607 293 0.051
ribonucleoside triphosphate catabolic process GO:0009203 72 0.051
organic substance biosynthetic process GO:1901576 323 0.051
regulation of rna biosynthetic process GO:2001141 165 0.049
regulation of cellular protein metabolic process GO:0032268 75 0.049
positive regulation of developmental process GO:0051094 408 0.049
positive regulation of developmental growth GO:0048639 354 0.049
purine ribonucleoside metabolic process GO:0046128 92 0.048
macromolecular complex subunit organization GO:0043933 320 0.048
cellular protein complex assembly GO:0043623 178 0.047
nucleotide catabolic process GO:0009166 77 0.047
macromolecule biosynthetic process GO:0009059 250 0.047
neuron development GO:0048666 199 0.047
organic cyclic compound biosynthetic process GO:1901362 195 0.047
fertilization GO:0009566 63 0.047
heterocycle catabolic process GO:0046700 119 0.046
nucleus localization GO:0051647 55 0.046
ribonucleoside metabolic process GO:0009119 98 0.046
protein complex subunit organization GO:0071822 280 0.046
purine nucleoside catabolic process GO:0006152 75 0.045
transcription dna templated GO:0006351 168 0.045
glycosyl compound catabolic process GO:1901658 79 0.044
purine containing compound metabolic process GO:0072521 95 0.044
negative regulation of post embryonic development GO:0048581 208 0.044
cellular localization GO:0051641 360 0.044
receptor mediated endocytosis GO:0006898 715 0.044
purine containing compound catabolic process GO:0072523 75 0.043
intracellular signal transduction GO:0035556 96 0.042
multi multicellular organism process GO:0044706 390 0.042
ribonucleotide catabolic process GO:0009261 75 0.041
purine ribonucleotide metabolic process GO:0009150 95 0.041
regulation of transcription dna templated GO:0006355 164 0.041
cell development GO:0048468 696 0.041
nucleoside metabolic process GO:0009116 99 0.041
regulation of growth GO:0040008 409 0.040
regulation of multicellular organismal development GO:2000026 317 0.040
negative regulation of multicellular organismal process GO:0051241 236 0.039
oogenesis GO:0048477 229 0.039
ribonucleotide metabolic process GO:0009259 99 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.039
single organism signaling GO:0044700 401 0.038
organic cyclic compound catabolic process GO:1901361 119 0.038
regulation of developmental growth GO:0048638 389 0.038
gene expression GO:0010467 412 0.038
cellular macromolecule biosynthetic process GO:0034645 247 0.036
positive regulation of multicellular organism growth GO:0040018 352 0.036
regulation of macromolecule biosynthetic process GO:0010556 189 0.036
germ cell development GO:0007281 351 0.035
sex differentiation GO:0007548 909 0.035
protein complex assembly GO:0006461 186 0.035
neurogenesis GO:0022008 236 0.035
purine ribonucleotide catabolic process GO:0009154 75 0.035
response to wounding GO:0009611 4 0.035
negative regulation of macromolecule metabolic process GO:0010605 229 0.034
positive regulation of cellular biosynthetic process GO:0031328 109 0.034
reproductive behavior GO:0019098 387 0.034
head development GO:0060322 1 0.034
organic substance transport GO:0071702 113 0.033
reproductive system development GO:0061458 850 0.033
dna metabolic process GO:0006259 74 0.033
nucleobase containing small molecule metabolic process GO:0055086 115 0.033
nucleoside triphosphate catabolic process GO:0009143 72 0.033
cell cycle process GO:0022402 482 0.032
signal transduction GO:0007165 317 0.032
negative regulation of cellular process GO:0048523 239 0.032
macromolecular complex assembly GO:0065003 193 0.032
cellular nitrogen compound biosynthetic process GO:0044271 192 0.032
pole plasm assembly GO:0007315 2 0.031
purine nucleoside triphosphate metabolic process GO:0009144 87 0.031
tissue development GO:0009888 112 0.031
establishment of organelle localization GO:0051656 123 0.030
cellular biosynthetic process GO:0044249 315 0.030
muscle structure development GO:0061061 191 0.028
protein modification process GO:0036211 207 0.028
cell division GO:0051301 262 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.028
single organism catabolic process GO:0044712 129 0.027
positive regulation of macromolecule metabolic process GO:0010604 149 0.026
regulation of multi organism process GO:0043900 69 0.025
anatomical structure formation involved in morphogenesis GO:0048646 250 0.025
inductive cell migration GO:0040039 145 0.025
oviposition GO:0018991 364 0.025
dna templated transcription elongation GO:0006354 1 0.024
neuron projection development GO:0031175 187 0.024
neuron differentiation GO:0030182 217 0.024
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.023
nucleoside monophosphate metabolic process GO:0009123 46 0.023
cellular component morphogenesis GO:0032989 318 0.023
positive regulation of gene expression GO:0010628 112 0.023
response to chemical GO:0042221 356 0.023
positive regulation of transcription dna templated GO:0045893 102 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.022
aromatic compound biosynthetic process GO:0019438 192 0.022
regulation of molecular function GO:0065009 89 0.022
positive regulation of cellular metabolic process GO:0031325 178 0.022
purine nucleotide metabolic process GO:0006163 95 0.021
positive regulation of metabolic process GO:0009893 187 0.021
regulation of localization GO:0032879 194 0.021
regulation of biosynthetic process GO:0009889 189 0.021
signaling GO:0023052 401 0.020
oxoacid metabolic process GO:0043436 47 0.020
actin filament based process GO:0030029 191 0.020
epithelium development GO:0060429 68 0.020
regulation of catabolic process GO:0009894 57 0.019
regulation of cell proliferation GO:0042127 105 0.019
phagocytosis engulfment GO:0006911 98 0.019
regulation of primary metabolic process GO:0080090 292 0.019
regulation of response to stimulus GO:0048583 243 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.019
protein localization GO:0008104 205 0.019
meiotic cell cycle process GO:1903046 170 0.019
ribonucleoside monophosphate metabolic process GO:0009161 45 0.019
posttranscriptional gene silencing by rna GO:0035194 143 0.018
protein oligomerization GO:0051259 4 0.018
cellular macromolecular complex assembly GO:0034622 184 0.018
muscle cell development GO:0055001 158 0.018
generation of neurons GO:0048699 235 0.018
centrosomal and pronuclear rotation GO:0035047 6 0.018
positive regulation of protein metabolic process GO:0051247 45 0.018
positive regulation of cellular component organization GO:0051130 34 0.018
cell proliferation GO:0008283 116 0.017
regulation of organelle organization GO:0033043 164 0.017
regulation of cell communication GO:0010646 176 0.017
multi organism behavior GO:0051705 389 0.017
organelle localization GO:0051640 127 0.017
nucleic acid metabolic process GO:0090304 299 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.017
regulation of signal transduction GO:0009966 135 0.017
positive regulation of rna biosynthetic process GO:1902680 102 0.017
axonal fasciculation GO:0007413 79 0.017
intracellular transport GO:0046907 77 0.017
atp catabolic process GO:0006200 27 0.017
meiotic chromosome segregation GO:0045132 139 0.016
positive regulation of rna metabolic process GO:0051254 103 0.016
chromosome segregation GO:0007059 180 0.016
membrane invagination GO:0010324 98 0.016
myofibril assembly GO:0030239 154 0.016
dna templated transcription initiation GO:0006352 3 0.016
secretion by cell GO:0032940 138 0.016
regulation of signaling GO:0023051 172 0.016
negative regulation of signaling GO:0023057 61 0.016
muscle cell differentiation GO:0042692 171 0.015
actomyosin structure organization GO:0031032 154 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of atp catabolic process GO:1903289 3 0.015
er associated ubiquitin dependent protein catabolic process GO:0030433 6 0.015
positive regulation of chromosome organization GO:2001252 2 0.015
organ morphogenesis GO:0009887 67 0.015
regulation of transport GO:0051049 91 0.015
negative regulation of gene expression GO:0010629 217 0.015
rna biosynthetic process GO:0032774 169 0.015
oocyte construction GO:0007308 2 0.014
organelle assembly GO:0070925 214 0.014
positive regulation of neuron differentiation GO:0045666 4 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.014
system process GO:0003008 136 0.014
meiotic nuclear division GO:0007126 300 0.014
atp metabolic process GO:0046034 42 0.014
rna interference GO:0016246 137 0.014
regulation of rna metabolic process GO:0051252 173 0.013
negative regulation of transporter activity GO:0032410 3 0.013
rna localization GO:0006403 3 0.013
cellular response to dna damage stimulus GO:0006974 41 0.013
Fly
oxidation reduction process GO:0055114 59 0.013
positive regulation of proteasomal protein catabolic process GO:1901800 1 0.013
gene silencing by rna GO:0031047 143 0.013
striated muscle cell differentiation GO:0051146 158 0.013
purine nucleoside metabolic process GO:0042278 92 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
single organism biosynthetic process GO:0044711 91 0.013
organic acid metabolic process GO:0006082 47 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.013
golgi vesicle transport GO:0048193 3 0.013
meiotic cell cycle GO:0051321 335 0.013
regulation of gene expression epigenetic GO:0040029 163 0.013
regulation of cellular component biogenesis GO:0044087 26 0.013
striated muscle cell development GO:0055002 157 0.013
response to abiotic stimulus GO:0009628 152 0.013
regulation of cellular catabolic process GO:0031329 51 0.012
regulation of apoptotic signaling pathway GO:2001233 1 0.012
establishment of nucleus localization GO:0040023 55 0.012
cuticle development GO:0042335 100 0.012
dendrite development GO:0016358 42 0.012
purine nucleoside monophosphate catabolic process GO:0009128 28 0.012
digestive system development GO:0055123 122 0.012
organelle fission GO:0048285 363 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.011
negative regulation of metabolic process GO:0009892 240 0.011
nitrogen compound transport GO:0071705 49 0.011
cell cell signaling GO:0007267 118 0.011
posttranscriptional gene silencing GO:0016441 143 0.011
detection of external stimulus GO:0009581 4 0.011
oocyte axis specification GO:0007309 2 0.011
muscle organ morphogenesis GO:0048644 4 0.011
detection of abiotic stimulus GO:0009582 4 0.011
regulation of cell division GO:0051302 142 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
phagocytosis GO:0006909 115 0.011
neuron recognition GO:0008038 83 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 43 0.011
membrane organization GO:0061024 135 0.010
positive regulation of cellular protein catabolic process GO:1903364 3 0.010
cell recognition GO:0008037 85 0.010
regulation of catalytic activity GO:0050790 78 0.010
pattern specification process GO:0007389 59 0.010
tube development GO:0035295 126 0.010
regulation of intracellular signal transduction GO:1902531 77 0.010
collagen and cuticulin based cuticle development GO:0040002 99 0.010

pbs-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023