Caenorhabditis elegans

0 known processes

ergo-1 (CELE_R09A1.1)

Protein ERGO-1

ergo-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism signaling GO:0044700 401 0.524
development of primary sexual characteristics GO:0045137 840 0.489
gonad development GO:0008406 840 0.344
sex differentiation GO:0007548 909 0.288
organelle organization GO:0006996 783 0.274
Fly
regulation of metabolic process GO:0019222 478 0.272
Zebrafish Worm Fly
genitalia development GO:0048806 741 0.259
embryo development ending in birth or egg hatching GO:0009792 2992 0.250
Worm
negative regulation of biological process GO:0048519 567 0.208
Zebrafish Worm Fly
positive regulation of cellular process GO:0048522 332 0.189
Fly
developmental process involved in reproduction GO:0003006 1165 0.182
Zebrafish Fly
establishment of localization GO:0051234 1171 0.173
signaling GO:0023052 401 0.171
reproductive system development GO:0061458 850 0.170
hermaphrodite genitalia development GO:0040035 734 0.161
single organism reproductive process GO:0044702 1196 0.136
Zebrafish Fly
signal transduction GO:0007165 317 0.134
embryo development GO:0009790 3052 0.132
Worm Fly
receptor mediated endocytosis GO:0006898 715 0.132
cellular component assembly GO:0022607 293 0.129
Fly
reproductive structure development GO:0048608 850 0.119
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.115
regulation of signal transduction GO:0009966 135 0.112
vesicle mediated transport GO:0016192 852 0.112
determination of adult lifespan GO:0008340 812 0.111
post embryonic development GO:0009791 2152 0.110
cytoskeleton organization GO:0007010 339 0.109
cell migration GO:0016477 306 0.100
positive regulation of macromolecule metabolic process GO:0010604 149 0.097
Fly
positive regulation of metabolic process GO:0009893 187 0.092
Fly
positive regulation of catalytic activity GO:0043085 59 0.089
regulation of response to stimulus GO:0048583 243 0.089
Fly
macromolecule localization GO:0033036 771 0.089
Fly
phosphorylation GO:0016310 116 0.087
regulation of biological quality GO:0065008 741 0.085
locomotion GO:0040011 1634 0.082
regulation of transport GO:0051049 91 0.082
lipid localization GO:0010876 573 0.081
cellular component biogenesis GO:0044085 297 0.079
Fly
mitotic cell cycle process GO:1903047 194 0.078
Fly
cell motility GO:0048870 313 0.078
regulation of developmental process GO:0050793 684 0.078
Fly
lipid storage GO:0019915 565 0.076
cell surface receptor signaling pathway GO:0007166 149 0.075
muscle structure development GO:0061061 191 0.075
microtubule based process GO:0007017 182 0.075
endocytosis GO:0006897 819 0.071
cellular protein complex assembly GO:0043623 178 0.070
positive regulation of developmental process GO:0051094 408 0.069
positive regulation of growth GO:0045927 369 0.069
cellular macromolecular complex assembly GO:0034622 184 0.068
Fly
maintenance of location GO:0051235 580 0.067
cellular component movement GO:0006928 388 0.067
spindle organization GO:0007051 92 0.066
transport GO:0006810 1093 0.066
actin filament based process GO:0030029 191 0.065
cell death GO:0008219 547 0.065
protein localization GO:0008104 205 0.065
Fly
growth GO:0040007 562 0.065
cell cycle GO:0007049 526 0.064
Fly
regulation of catalytic activity GO:0050790 78 0.062
regulation of phosphate metabolic process GO:0019220 81 0.062
multicellular organismal aging GO:0010259 812 0.061
regulation of signaling GO:0023051 172 0.059
positive regulation of multicellular organismal process GO:0051240 417 0.059
positive regulation of catabolic process GO:0009896 38 0.059
Fly
positive regulation of molecular function GO:0044093 61 0.057
protein complex assembly GO:0006461 186 0.057
regulation of multicellular organism growth GO:0040014 373 0.056
phosphorus metabolic process GO:0006793 232 0.055
protein complex subunit organization GO:0071822 280 0.054
response to heat GO:0009408 50 0.054
response to external stimulus GO:0009605 289 0.051
Fly
localization of cell GO:0051674 313 0.049
protein complex biogenesis GO:0070271 186 0.048
regulation of macromolecule metabolic process GO:0060255 421 0.048
Zebrafish Worm Fly
multi organism reproductive process GO:0044703 867 0.047
Zebrafish Fly
oxoacid metabolic process GO:0043436 47 0.047
response to chemical GO:0042221 356 0.046
Worm
response to wounding GO:0009611 4 0.044
cell cell signaling GO:0007267 118 0.043
cell cycle process GO:0022402 482 0.042
Fly
actin cytoskeleton organization GO:0030036 184 0.041
mitotic spindle organization GO:0007052 81 0.041
aging GO:0007568 812 0.040
regulation of multicellular organismal process GO:0051239 726 0.039
Fly
cellular response to stress GO:0033554 162 0.039
macromolecular complex subunit organization GO:0043933 320 0.039
Fly
positive regulation of developmental growth GO:0048639 354 0.038
regulation of cellular metabolic process GO:0031323 305 0.038
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.038
Zebrafish Worm Fly
multicellular organism growth GO:0035264 385 0.038
embryonic morphogenesis GO:0048598 152 0.038
positive regulation of multicellular organism growth GO:0040018 352 0.037
cellular protein modification process GO:0006464 207 0.037
cellular ketone metabolic process GO:0042180 14 0.036
regulation of cellular ketone metabolic process GO:0010565 3 0.036
multicellular organismal reproductive process GO:0048609 815 0.036
Zebrafish Fly
gamete generation GO:0007276 461 0.035
Zebrafish Fly
single organism organelle organization GO:1902589 501 0.035
Fly
apoptotic cell clearance GO:0043277 111 0.034
regulation of localization GO:0032879 194 0.034
Fly
regulation of developmental growth GO:0048638 389 0.034
positive regulation of biosynthetic process GO:0009891 109 0.034
cellular biosynthetic process GO:0044249 315 0.033
Fly
positive regulation of cellular metabolic process GO:0031325 178 0.033
Fly
phosphate containing compound metabolic process GO:0006796 232 0.032
cell development GO:0048468 696 0.032
Zebrafish Fly
organ development GO:0048513 1102 0.032
establishment of organelle localization GO:0051656 123 0.032
protein metabolic process GO:0019538 422 0.031
protein modification process GO:0036211 207 0.031
carboxylic acid metabolic process GO:0019752 34 0.030
actomyosin structure organization GO:0031032 154 0.030
programmed cell death GO:0012501 500 0.030
regulation of molecular function GO:0065009 89 0.030
regulation of organ morphogenesis GO:2000027 4 0.030
regulation of cellular catabolic process GO:0031329 51 0.030
Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.030
Fly
regulation of cellular protein metabolic process GO:0032268 75 0.029
membrane organization GO:0061024 135 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.029
Fly
developmental growth GO:0048589 412 0.029
regulation of catabolic process GO:0009894 57 0.029
Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.029
Fly
cytokinesis GO:0000910 80 0.029
small molecule metabolic process GO:0044281 186 0.029
sexual reproduction GO:0019953 546 0.028
Zebrafish Fly
nucleobase containing compound metabolic process GO:0006139 406 0.028
Zebrafish Worm Fly
positive regulation of rna biosynthetic process GO:1902680 102 0.027
regulation of phosphorylation GO:0042325 45 0.027
response to biotic stimulus GO:0009607 101 0.026
Fly
head development GO:0060322 1 0.026
regulation of cellular component organization GO:0051128 248 0.026
Fly
phagocytosis GO:0006909 115 0.026
macromolecule modification GO:0043412 218 0.025
cellular protein metabolic process GO:0044267 279 0.025
body morphogenesis GO:0010171 620 0.025
gene expression GO:0010467 412 0.025
Zebrafish Worm Fly
positive regulation of cellular catabolic process GO:0031331 35 0.025
Fly
cellular amino acid metabolic process GO:0006520 15 0.024
gene silencing by rna GO:0031047 143 0.024
Zebrafish Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.024
Fly
dna geometric change GO:0032392 3 0.023
regulation of growth GO:0040008 409 0.023
regulation of nitrogen compound metabolic process GO:0051171 222 0.022
Fly
behavior GO:0007610 527 0.022
cuticle development GO:0042335 100 0.022
inductive cell migration GO:0040039 145 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
protein oligomerization GO:0051259 4 0.022
organic substance biosynthetic process GO:1901576 323 0.022
Fly
digestive tract morphogenesis GO:0048546 76 0.022
macromolecular complex assembly GO:0065003 193 0.022
Fly
engulfment of apoptotic cell GO:0043652 94 0.021
regulation of cell proliferation GO:0042127 105 0.021
phagocytosis engulfment GO:0006911 98 0.021
establishment of localization in cell GO:0051649 318 0.021
single organism biosynthetic process GO:0044711 91 0.021
multi organism behavior GO:0051705 389 0.021
rna biosynthetic process GO:0032774 169 0.021
Fly
negative regulation of cellular process GO:0048523 239 0.021
Fly
response to abiotic stimulus GO:0009628 152 0.021
response to bacterium GO:0009617 86 0.021
Fly
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.021
nucleic acid metabolic process GO:0090304 299 0.020
Zebrafish Worm Fly
membrane invagination GO:0010324 98 0.020
cellular component morphogenesis GO:0032989 318 0.020
Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.020
Worm Fly
chromosome organization involved in meiosis GO:0070192 25 0.019
regulation of protein metabolic process GO:0051246 81 0.019
cell cycle g1 s phase transition GO:0044843 2 0.019
regulation of gene expression epigenetic GO:0040029 163 0.019
Worm Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.019
Fly
digestive tract development GO:0048565 122 0.019
regulation of behavior GO:0050795 97 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.018
Fly
regulation of cell communication GO:0010646 176 0.018
single organism transport GO:0044765 447 0.018
negative regulation of developmental process GO:0051093 227 0.018
Fly
positive regulation of cellular component organization GO:0051130 34 0.018
protein deubiquitination GO:0016579 2 0.018
protein phosphorylation GO:0006468 85 0.018
epithelial cell proliferation GO:0050673 1 0.018
positive regulation of cellular biosynthetic process GO:0031328 109 0.018
amine metabolic process GO:0009308 15 0.017
canonical wnt signaling pathway GO:0060070 3 0.017
internal peptidyl lysine acetylation GO:0018393 3 0.017
lipid metabolic process GO:0006629 77 0.017
multi multicellular organism process GO:0044706 390 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
multicellular organismal reproductive behavior GO:0033057 384 0.017
cellular amine metabolic process GO:0044106 15 0.017
response to temperature stimulus GO:0009266 66 0.017
myosin filament assembly GO:0031034 138 0.017
organelle localization GO:0051640 127 0.016
myosin filament organization GO:0031033 138 0.016
protein catabolic process GO:0030163 162 0.016
female gamete generation GO:0007292 254 0.016
Fly
regulation of phosphorus metabolic process GO:0051174 81 0.016
establishment or maintenance of cell polarity GO:0007163 63 0.016
neuron differentiation GO:0030182 217 0.015
neuron projection development GO:0031175 187 0.015
system process GO:0003008 136 0.015
regulation of cell migration GO:0030334 55 0.015
regulation of cell projection assembly GO:0060491 3 0.015
macromolecule biosynthetic process GO:0009059 250 0.015
Fly
cell proliferation GO:0008283 116 0.015
striated muscle myosin thick filament assembly GO:0071688 138 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
Fly
organic acid metabolic process GO:0006082 47 0.014
positive regulation of chromosome organization GO:2001252 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 51 0.014
gene silencing GO:0016458 143 0.014
Zebrafish Worm Fly
cellular catabolic process GO:0044248 199 0.014
Fly
g1 s transition of mitotic cell cycle GO:0000082 2 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
male gamete generation GO:0048232 41 0.014
Fly
muscle cell differentiation GO:0042692 171 0.014
regulation of cell motility GO:2000145 57 0.014
regulation of cytoskeleton organization GO:0051493 41 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
regulation of cellular component movement GO:0051270 62 0.013
positive regulation of protein metabolic process GO:0051247 45 0.013
epithelial tube morphogenesis GO:0060562 1 0.013
regulation of cytoplasmic transport GO:1903649 3 0.013
intracellular signal transduction GO:0035556 96 0.013
rna metabolic process GO:0016070 228 0.013
Zebrafish Worm Fly
multicellular organism reproduction GO:0032504 819 0.013
Zebrafish Fly
regulation of epithelial cell proliferation GO:0050678 1 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.013
positive regulation of gene expression GO:0010628 112 0.013
Fly
muscle cell development GO:0055001 158 0.013
negative regulation of signaling GO:0023057 61 0.013
internal protein amino acid acetylation GO:0006475 3 0.012
regulation of transferase activity GO:0051338 31 0.012
response to topologically incorrect protein GO:0035966 82 0.012
organophosphate metabolic process GO:0019637 125 0.012
biosynthetic process GO:0009058 323 0.012
Fly
organelle assembly GO:0070925 214 0.012
peptidyl tyrosine phosphorylation GO:0018108 2 0.012
developmental induction GO:0031128 1 0.012
endoplasmic reticulum unfolded protein response GO:0030968 66 0.012
sensory organ morphogenesis GO:0090596 2 0.012
regulation of biosynthetic process GO:0009889 189 0.012
Fly
regulation of protein modification process GO:0031399 46 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
Fly
regulation of gene expression GO:0010468 366 0.011
Zebrafish Worm Fly
regulation of phagocytosis engulfment GO:0060099 17 0.011
regulation of chromatin modification GO:1903308 2 0.011
peptidyl lysine acetylation GO:0018394 3 0.011
digestive system development GO:0055123 122 0.011
positive regulation of cell communication GO:0010647 69 0.011
regulation of locomotion GO:0040012 161 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
striated muscle cell differentiation GO:0051146 158 0.011
regulation of anatomical structure size GO:0090066 46 0.011
myofibril assembly GO:0030239 154 0.011
single organism catabolic process GO:0044712 129 0.011
negative regulation of cell communication GO:0010648 61 0.011
organic substance transport GO:0071702 113 0.011
organonitrogen compound metabolic process GO:1901564 151 0.010
mitochondrion organization GO:0007005 20 0.010
positive regulation of transcription dna templated GO:0045893 102 0.010
negative regulation of multicellular organismal process GO:0051241 236 0.010
cell cycle phase transition GO:0044770 19 0.010
posttranscriptional gene silencing by rna GO:0035194 143 0.010
Worm Fly
regulation of primary metabolic process GO:0080090 292 0.010
Fly
apoptotic process GO:0006915 478 0.010

ergo-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.019
reproductive organ cancer DOID:193 0 0.019
cancer DOID:162 0 0.019
female reproductive organ cancer DOID:120 0 0.019
disease of anatomical entity DOID:7 0 0.014
cardiovascular system disease DOID:1287 0 0.011