Caenorhabditis elegans

8 known processes

ikke-1 (CELE_R107.4)

Protein IKKE-1

ikke-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.553
signaling GO:0023052 401 0.187
organic substance catabolic process GO:1901575 294 0.156
regulation of multicellular organismal process GO:0051239 726 0.139
establishment of localization GO:0051234 1171 0.135
cell death GO:0008219 547 0.134
regulation of biological quality GO:0065008 741 0.130
locomotion GO:0040011 1634 0.121
embryo development GO:0009790 3052 0.118
organelle organization GO:0006996 783 0.115
vesicle mediated transport GO:0016192 852 0.112
aging GO:0007568 812 0.101
single organism reproductive process GO:0044702 1196 0.097
lipid localization GO:0010876 573 0.095
single organism transport GO:0044765 447 0.092
macromolecule localization GO:0033036 771 0.087
single organism signaling GO:0044700 401 0.085
multicellular organismal aging GO:0010259 812 0.083
protein metabolic process GO:0019538 422 0.082
lipid storage GO:0019915 565 0.082
regulation of localization GO:0032879 194 0.081
transport GO:0006810 1093 0.080
determination of adult lifespan GO:0008340 812 0.078
negative regulation of biological process GO:0048519 567 0.078
signal transduction GO:0007165 317 0.077
maintenance of location GO:0051235 580 0.076
defense response GO:0006952 296 0.070
programmed cell death GO:0012501 500 0.070
secretion by cell GO:0032940 138 0.069
response to abiotic stimulus GO:0009628 152 0.068
post embryonic development GO:0009791 2152 0.066
establishment of localization in cell GO:0051649 318 0.065
cellular component movement GO:0006928 388 0.063
regulation of response to stimulus GO:0048583 243 0.059
death GO:0016265 547 0.056
cellular localization GO:0051641 360 0.053
organ development GO:0048513 1102 0.052
positive regulation of cellular process GO:0048522 332 0.052
cellular protein modification process GO:0006464 207 0.052
endosomal transport GO:0016197 26 0.049
single organism localization GO:1902578 518 0.047
catabolic process GO:0009056 318 0.047
regulation of synapse assembly GO:0051963 2 0.046
neuron differentiation GO:0030182 217 0.046
response to external stimulus GO:0009605 289 0.045
macromolecule catabolic process GO:0009057 202 0.045
immune response GO:0006955 192 0.042
body morphogenesis GO:0010171 620 0.041
endocytosis GO:0006897 819 0.041
asymmetric cell division GO:0008356 36 0.041
neurological system process GO:0050877 53 0.040
localization of cell GO:0051674 313 0.040
regulation of signaling GO:0023051 172 0.040
apoptotic process GO:0006915 478 0.039
phosphate containing compound metabolic process GO:0006796 232 0.039
receptor mediated endocytosis GO:0006898 715 0.039
anterior posterior pattern specification GO:0009952 27 0.037
regulation of cell differentiation GO:0045595 81 0.037
regulation of macromolecule metabolic process GO:0060255 421 0.036
system process GO:0003008 136 0.035
regulation of multicellular organism growth GO:0040014 373 0.035
cellular protein complex assembly GO:0043623 178 0.035
positive regulation of cell migration GO:0030335 3 0.035
cellular component assembly GO:0022607 293 0.035
purine nucleoside catabolic process GO:0006152 75 0.035
regulation of multicellular organismal development GO:2000026 317 0.034
neuron development GO:0048666 199 0.034
secretion GO:0046903 147 0.034
defense response to gram negative bacterium GO:0050829 64 0.032
organelle fission GO:0048285 363 0.032
development of primary sexual characteristics GO:0045137 840 0.032
negative regulation of metabolic process GO:0009892 240 0.031
female meiotic division GO:0007143 17 0.031
synaptic vesicle endocytosis GO:0048488 3 0.031
oviposition GO:0018991 364 0.030
cell cycle process GO:0022402 482 0.030
positive regulation of developmental growth GO:0048639 354 0.029
multicellular organism growth GO:0035264 385 0.029
regulation of developmental process GO:0050793 684 0.028
cell cycle GO:0007049 526 0.028
organonitrogen compound metabolic process GO:1901564 151 0.028
developmental process involved in reproduction GO:0003006 1165 0.028
negative regulation of cellular process GO:0048523 239 0.027
regulation of gene expression GO:0010468 366 0.026
negative regulation of bmp signaling pathway GO:0030514 1 0.026
cellular catabolic process GO:0044248 199 0.026
intracellular transport GO:0046907 77 0.025
single organism intracellular transport GO:1902582 70 0.025
regulation of metabolic process GO:0019222 478 0.025
positive regulation of developmental process GO:0051094 408 0.025
response to wounding GO:0009611 4 0.025
regulation of nucleoside metabolic process GO:0009118 37 0.024
organic substance biosynthetic process GO:1901576 323 0.024
macromolecular complex subunit organization GO:0043933 320 0.024
sensory organ morphogenesis GO:0090596 2 0.024
negative regulation of multicellular organismal process GO:0051241 236 0.024
response to temperature stimulus GO:0009266 66 0.024
regulation of catalytic activity GO:0050790 78 0.023
head development GO:0060322 1 0.023
establishment of protein localization to membrane GO:0090150 3 0.023
multi organism reproductive process GO:0044703 867 0.023
cellular component biogenesis GO:0044085 297 0.023
regionalization GO:0003002 31 0.023
protein catabolic process GO:0030163 162 0.022
spindle localization GO:0051653 51 0.022
cell development GO:0048468 696 0.022
regulation of growth GO:0040008 409 0.022
cellular nitrogen compound biosynthetic process GO:0044271 192 0.022
positive regulation of growth GO:0045927 369 0.022
reproductive system development GO:0061458 850 0.022
membrane organization GO:0061024 135 0.022
protein complex subunit organization GO:0071822 280 0.021
nucleobase containing compound metabolic process GO:0006139 406 0.021
cell division GO:0051301 262 0.021
sex differentiation GO:0007548 909 0.021
intracellular protein transmembrane transport GO:0065002 4 0.021
negative regulation of developmental process GO:0051093 227 0.020
growth GO:0040007 562 0.020
cytoskeleton organization GO:0007010 339 0.020
positive regulation of multicellular organism growth GO:0040018 352 0.020
response to chemical GO:0042221 356 0.020
defense response to bacterium GO:0042742 86 0.020
gonad development GO:0008406 840 0.020
developmental growth GO:0048589 412 0.019
generation of neurons GO:0048699 235 0.019
macromolecular complex assembly GO:0065003 193 0.019
organic cyclic compound biosynthetic process GO:1901362 195 0.019
protein complex biogenesis GO:0070271 186 0.019
engulfment of apoptotic cell GO:0043652 94 0.019
protein localization GO:0008104 205 0.018
organelle assembly GO:0070925 214 0.018
cellular response to organic substance GO:0071310 119 0.018
gtp catabolic process GO:0006184 46 0.018
necrotic cell death GO:0070265 29 0.017
response to other organism GO:0051707 101 0.017
cellular nitrogen compound catabolic process GO:0044270 119 0.017
nucleoside metabolic process GO:0009116 99 0.017
ras protein signal transduction GO:0007265 31 0.017
regulation of ras protein signal transduction GO:0046578 41 0.017
muscle cell differentiation GO:0042692 171 0.017
response to bacterium GO:0009617 86 0.016
tissue development GO:0009888 112 0.016
phosphorus metabolic process GO:0006793 232 0.016
enzyme linked receptor protein signaling pathway GO:0007167 50 0.016
response to external biotic stimulus GO:0043207 101 0.016
biosynthetic process GO:0009058 323 0.016
reproductive structure development GO:0048608 850 0.015
regulation of response to wounding GO:1903034 1 0.015
positive regulation of multicellular organismal process GO:0051240 417 0.015
intracellular receptor signaling pathway GO:0030522 2 0.015
polarity specification of anterior posterior axis GO:0009949 8 0.015
phagocytosis engulfment GO:0006911 98 0.015
sexual reproduction GO:0019953 546 0.015
striated muscle cell development GO:0055002 157 0.015
response to organic substance GO:0010033 131 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
actin cytoskeleton reorganization GO:0031532 4 0.014
small molecule metabolic process GO:0044281 186 0.014
protein transmembrane transport GO:0071806 4 0.014
cell migration GO:0016477 306 0.014
regulation of cell communication GO:0010646 176 0.014
muscle cell development GO:0055001 158 0.014
amine metabolic process GO:0009308 15 0.014
myosin filament organization GO:0031033 138 0.014
neurogenesis GO:0022008 236 0.014
purine nucleotide metabolic process GO:0006163 95 0.014
inductive cell migration GO:0040039 145 0.014
negative regulation of vulval development GO:0040027 206 0.014
negative regulation of cell communication GO:0010648 61 0.014
regulation of intracellular signal transduction GO:1902531 77 0.013
neuron projection development GO:0031175 187 0.013
cellular response to chemical stimulus GO:0070887 129 0.013
defense response to other organism GO:0098542 100 0.013
behavior GO:0007610 527 0.013
organic substance transport GO:0071702 113 0.013
peptide metabolic process GO:0006518 7 0.013
regulation of multi organism process GO:0043900 69 0.013
neuromuscular junction development GO:0007528 2 0.013
regulation of molecular function GO:0065009 89 0.013
endodermal cell differentiation GO:0035987 18 0.013
regeneration GO:0031099 4 0.013
muscle structure development GO:0061061 191 0.013
nucleoside phosphate catabolic process GO:1901292 77 0.013
nucleoside triphosphate catabolic process GO:0009143 72 0.013
regulation of primary metabolic process GO:0080090 292 0.013
protein complex assembly GO:0006461 186 0.013
cell cell signaling GO:0007267 118 0.012
cell surface receptor signaling pathway GO:0007166 149 0.012
response to biotic stimulus GO:0009607 101 0.012
heterocycle catabolic process GO:0046700 119 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
regulation of developmental growth GO:0048638 389 0.012
regulation of post embryonic development GO:0048580 260 0.012
nucleoside phosphate metabolic process GO:0006753 108 0.012
organonitrogen compound catabolic process GO:1901565 90 0.012
purine ribonucleotide catabolic process GO:0009154 75 0.012
membrane invagination GO:0010324 98 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.012
cellular biosynthetic process GO:0044249 315 0.012
feminization of hermaphroditic germ line GO:0040022 34 0.012
negative regulation of cellular metabolic process GO:0031324 95 0.012
regulation of bmp signaling pathway GO:0030510 3 0.011
myosin filament assembly GO:0031034 138 0.011
actin filament based process GO:0030029 191 0.011
cell type specific apoptotic process GO:0097285 4 0.011
positive regulation of cell death GO:0010942 38 0.011
myofibril assembly GO:0030239 154 0.011
regulation of fibroblast proliferation GO:0048145 1 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
innate immune response GO:0045087 190 0.011
ion transport GO:0006811 113 0.011
negative regulation of response to stimulus GO:0048585 73 0.011
meiotic cell cycle process GO:1903046 170 0.011
apoptotic cell clearance GO:0043277 111 0.011
asymmetric protein localization GO:0008105 35 0.011
collagen and cuticulin based cuticle development GO:0040002 99 0.011
regulation of vulval development GO:0040028 248 0.011
protein transport GO:0015031 45 0.011
skeletal muscle organ development GO:0060538 3 0.011
rho protein signal transduction GO:0007266 2 0.011
cellular component morphogenesis GO:0032989 318 0.011
nucleoside catabolic process GO:0009164 78 0.011
ribose phosphate metabolic process GO:0019693 99 0.011
actomyosin structure organization GO:0031032 154 0.011
lipid metabolic process GO:0006629 77 0.011
regulation of locomotion GO:0040012 161 0.010
regulation of ras gtpase activity GO:0032318 21 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
regulation of organelle organization GO:0033043 164 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
macromolecule biosynthetic process GO:0009059 250 0.010
female gamete generation GO:0007292 254 0.010

ikke-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.012