Caenorhabditis elegans

127 known processes

lis-1 (CELE_T03F6.5)

Protein LIS-1

lis-1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
single organism reproductive process GO:0044702 1196 0.422
embryo development GO:0009790 3052 0.370
transport GO:0006810 1093 0.344
embryo development ending in birth or egg hatching GO:0009792 2992 0.341
vesicle mediated transport GO:0016192 852 0.325
single organism localization GO:1902578 518 0.304
establishment of localization GO:0051234 1171 0.287
negative regulation of biological process GO:0048519 567 0.282
Mouse Rat Fly
protein metabolic process GO:0019538 422 0.277
Fly
locomotion GO:0040011 1634 0.267
post embryonic development GO:0009791 2152 0.260
multicellular organismal reproductive process GO:0048609 815 0.245
Mouse Fly
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.234
Mouse Fly
macromolecule modification GO:0043412 218 0.223
sexual reproduction GO:0019953 546 0.222
regulation of vulval development GO:0040028 248 0.213
death GO:0016265 547 0.212
single organism signaling GO:0044700 401 0.212
establishment of localization in cell GO:0051649 318 0.209
negative regulation of vulval development GO:0040027 206 0.202
regulation of macromolecule metabolic process GO:0060255 421 0.198
Fly
regulation of gene expression GO:0010468 366 0.194
Fly
cellular localization GO:0051641 360 0.191
developmental process involved in reproduction GO:0003006 1165 0.190
Mouse Fly
regulation of metabolic process GO:0019222 478 0.189
Mouse Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.186
Fly
organelle organization GO:0006996 783 0.185
macromolecule localization GO:0033036 771 0.182
Zebrafish Mouse Fly
nucleic acid templated transcription GO:0097659 169 0.181
signal transduction GO:0007165 317 0.181
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 406 0.180
signaling GO:0023052 401 0.178
female gamete generation GO:0007292 254 0.175
Fly
protein modification process GO:0036211 207 0.174
single organism transport GO:0044765 447 0.172
negative regulation of nematode larval development GO:0061064 208 0.167
nucleobase containing compound biosynthetic process GO:0034654 184 0.165
germ cell development GO:0007281 351 0.163
Mouse Fly
reproductive system development GO:0061458 850 0.161
gene expression GO:0010467 412 0.161
Fly
cellular component biogenesis GO:0044085 297 0.161
apoptotic process GO:0006915 478 0.158
endocytosis GO:0006897 819 0.155
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.152
regulation of rna biosynthetic process GO:2001141 165 0.150
Fly
genitalia development GO:0048806 741 0.148
gonad development GO:0008406 840 0.148
regulation of cellular component organization GO:0051128 248 0.147
Rat Fly
regulation of developmental process GO:0050793 684 0.146
Rat Fly
programmed cell death GO:0012501 500 0.142
organ development GO:0048513 1102 0.142
multi organism reproductive process GO:0044703 867 0.141
vulval development GO:0040025 333 0.139
regulation of post embryonic development GO:0048580 260 0.138
regulation of nucleic acid templated transcription GO:1903506 165 0.138
Fly
multicellular organism reproduction GO:0032504 819 0.138
Mouse Fly
cell development GO:0048468 696 0.135
Human Mouse Rat Fly
determination of adult lifespan GO:0008340 812 0.130
wnt signaling pathway GO:0016055 27 0.127
negative regulation of post embryonic development GO:0048581 208 0.123
cellular macromolecule biosynthetic process GO:0034645 247 0.122
Fly
cellular protein metabolic process GO:0044267 279 0.121
Fly
regulation of rna metabolic process GO:0051252 173 0.117
Fly
positive regulation of cellular process GO:0048522 332 0.115
Mouse Rat Fly
transcription dna templated GO:0006351 168 0.115
regulation of cellular metabolic process GO:0031323 305 0.113
Mouse Fly
development of primary sexual characteristics GO:0045137 840 0.112
organic cyclic compound biosynthetic process GO:1901362 195 0.112
reproductive structure development GO:0048608 850 0.112
rna biosynthetic process GO:0032774 169 0.111
regulation of biosynthetic process GO:0009889 189 0.110
Fly
cytoskeleton organization GO:0007010 339 0.110
gamete generation GO:0007276 461 0.109
Mouse Fly
sex differentiation GO:0007548 909 0.109
receptor mediated endocytosis GO:0006898 715 0.107
cellular protein modification process GO:0006464 207 0.106
single organism organelle organization GO:1902589 501 0.104
cell fate commitment GO:0045165 139 0.104
Fly
growth GO:0040007 562 0.102
Rat
transcription from rna polymerase ii promoter GO:0006366 149 0.100
cell cycle GO:0007049 526 0.098
regulation of multicellular organismal process GO:0051239 726 0.097
Rat Fly
post embryonic organ development GO:0048569 336 0.095
establishment of organelle localization GO:0051656 123 0.095
cellular biosynthetic process GO:0044249 315 0.094
Fly
phosphate containing compound metabolic process GO:0006796 232 0.094
Mouse
cellular component assembly GO:0022607 293 0.094
cellular component movement GO:0006928 388 0.091
neurogenesis GO:0022008 236 0.090
Human Mouse Rat Fly
protein localization GO:0008104 205 0.090
Zebrafish Mouse Fly
rna metabolic process GO:0016070 228 0.090
negative regulation of developmental process GO:0051093 227 0.089
Rat Fly
cell death GO:0008219 547 0.089
regulation of primary metabolic process GO:0080090 292 0.088
Mouse Fly
biosynthetic process GO:0009058 323 0.087
Fly
regulation of multicellular organismal development GO:2000026 317 0.087
Rat Fly
golgi vesicle transport GO:0048193 3 0.086
generation of neurons GO:0048699 235 0.086
Human Mouse Rat Fly
macromolecule biosynthetic process GO:0009059 250 0.086
Fly
negative regulation of metabolic process GO:0009892 240 0.086
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.085
Fly
organic substance biosynthetic process GO:1901576 323 0.084
Fly
behavior GO:0007610 527 0.083
Human Mouse
organelle assembly GO:0070925 214 0.083
regulation of nitrogen compound metabolic process GO:0051171 222 0.082
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.082
body morphogenesis GO:0010171 620 0.081
regulation of transcription dna templated GO:0006355 164 0.080
Fly
phosphorus metabolic process GO:0006793 232 0.080
Mouse
positive regulation of cellular metabolic process GO:0031325 178 0.080
multicellular organismal aging GO:0010259 812 0.079
regulation of signaling GO:0023051 172 0.079
Mouse Fly
regulation of biological quality GO:0065008 741 0.079
Zebrafish Rat Fly
negative regulation of multicellular organismal process GO:0051241 236 0.079
Rat
cell cycle process GO:0022402 482 0.078
protein catabolic process GO:0030163 162 0.078
macromolecular complex subunit organization GO:0043933 320 0.078
single organism cellular localization GO:1902580 72 0.078
cellular nitrogen compound biosynthetic process GO:0044271 192 0.076
response to chemical GO:0042221 356 0.075
Mouse Fly
regulation of localization GO:0032879 194 0.075
Fly
regulation of nematode larval development GO:0061062 260 0.075
protein complex subunit organization GO:0071822 280 0.073
organelle localization GO:0051640 127 0.073
positive regulation of multicellular organismal process GO:0051240 417 0.072
Rat
hermaphrodite genitalia development GO:0040035 734 0.072
cell division GO:0051301 262 0.071
Rat Fly
organic substance transport GO:0071702 113 0.071
Mouse Fly
regulation of cytoplasmic transport GO:1903649 3 0.070
cell surface receptor signaling pathway GO:0007166 149 0.070
Mouse Fly
positive regulation of transcription dna templated GO:0045893 102 0.070
single fertilization GO:0007338 61 0.069
aging GO:0007568 812 0.067
cell migration GO:0016477 306 0.067
Human Mouse Rat Fly
oocyte differentiation GO:0009994 45 0.066
Fly
organic substance catabolic process GO:1901575 294 0.065
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.065
regulation of response to stimulus GO:0048583 243 0.065
Mouse Fly
cellular protein localization GO:0034613 75 0.064
Fly
aromatic compound biosynthetic process GO:0019438 192 0.063
catabolic process GO:0009056 318 0.063
Mouse
oogenesis GO:0048477 229 0.063
Fly
regulation of cell division GO:0051302 142 0.061
microtubule based process GO:0007017 182 0.061
oocyte development GO:0048599 44 0.060
Fly
lipid storage GO:0019915 565 0.060
regulation of signal transduction GO:0009966 135 0.059
Mouse Fly
lipid localization GO:0010876 573 0.058
maintenance of location GO:0051235 580 0.058
nervous system development GO:0007399 253 0.058
Human Zebrafish Mouse Rat Fly
tissue development GO:0009888 112 0.057
Fly
sensory organ morphogenesis GO:0090596 2 0.057
Fly
small molecule metabolic process GO:0044281 186 0.056
Mouse
macromolecule catabolic process GO:0009057 202 0.056
nucleic acid metabolic process GO:0090304 299 0.056
ribosome biogenesis GO:0042254 4 0.055
intracellular transport GO:0046907 77 0.055
Mouse Fly
anatomical structure formation involved in morphogenesis GO:0048646 250 0.055
Mouse Fly
chromatin modification GO:0016568 32 0.054
regulation of macromolecule biosynthetic process GO:0010556 189 0.053
Fly
localization of cell GO:0051674 313 0.052
Human Mouse Rat Fly
head development GO:0060322 1 0.052
Human Zebrafish Mouse Rat Fly
meiotic nuclear division GO:0007126 300 0.051
canonical wnt signaling pathway GO:0060070 3 0.050
regulation of cellular biosynthetic process GO:0031326 189 0.050
Fly
developmental growth GO:0048589 412 0.050
Rat
regulation of multicellular organism growth GO:0040014 373 0.050
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.050
Mouse Fly
chemotaxis GO:0006935 120 0.049
Fly
multi multicellular organism process GO:0044706 390 0.049
positive regulation of developmental process GO:0051094 408 0.049
Rat
actin filament based process GO:0030029 191 0.049
Mouse
regulation of growth GO:0040008 409 0.049
Rat
mitotic cell cycle process GO:1903047 194 0.048
macromolecular complex assembly GO:0065003 193 0.048
cellular macromolecular complex assembly GO:0034622 184 0.048
intracellular signal transduction GO:0035556 96 0.048
Mouse
covalent chromatin modification GO:0016569 30 0.048
negative regulation of gene expression GO:0010629 217 0.047
multicellular organismal reproductive behavior GO:0033057 384 0.046
muscle tissue development GO:0060537 1 0.046
positive regulation of intracellular transport GO:0032388 2 0.046
Fly
negative regulation of macromolecule metabolic process GO:0010605 229 0.046
single organism intracellular transport GO:1902582 70 0.045
Mouse Fly
vesicle localization GO:0051648 24 0.045
chromosome organization GO:0051276 104 0.044
immune response GO:0006955 192 0.044
oviposition GO:0018991 364 0.044
organonitrogen compound metabolic process GO:1901564 151 0.043
Mouse
chromatin organization GO:0006325 32 0.042
regulation of gene expression epigenetic GO:0040029 163 0.042
neuron differentiation GO:0030182 217 0.042
Human Rat Fly
meiotic cell cycle GO:0051321 335 0.041
heterocycle biosynthetic process GO:0018130 187 0.041
phagocytosis GO:0006909 115 0.041
cellular macromolecule localization GO:0070727 75 0.041
Fly
gene silencing by rna GO:0031047 143 0.040
establishment of vesicle localization GO:0051650 23 0.040
negative regulation of response to stimulus GO:0048585 73 0.040
Mouse
regulation of developmental growth GO:0048638 389 0.040
Rat
reproductive behavior GO:0019098 387 0.040
positive regulation of macromolecule metabolic process GO:0010604 149 0.040
mitotic spindle organization GO:0007052 81 0.040
positive regulation of rna metabolic process GO:0051254 103 0.040
response to wounding GO:0009611 4 0.039
actin cytoskeleton organization GO:0030036 184 0.039
Mouse
cellular response to stress GO:0033554 162 0.039
Mouse
cell motility GO:0048870 313 0.039
Human Mouse Rat Fly
regulation of nuclear division GO:0051783 115 0.039
positive regulation of cellular biosynthetic process GO:0031328 109 0.038
dauer larval development GO:0040024 92 0.038
multi organism reproductive behavior GO:0044705 387 0.037
multicellular organism growth GO:0035264 385 0.037
molting cycle GO:0042303 281 0.037
regulation of cell communication GO:0010646 176 0.037
Mouse Fly
protein complex biogenesis GO:0070271 186 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.037
histone modification GO:0016570 30 0.037
multi organism behavior GO:0051705 389 0.037
regulation of nucleocytoplasmic transport GO:0046822 3 0.036
organ morphogenesis GO:0009887 67 0.036
Human Zebrafish Fly
posttranscriptional regulation of gene expression GO:0010608 166 0.036
Fly
membrane organization GO:0061024 135 0.036
negative regulation of cellular process GO:0048523 239 0.036
Mouse Rat Fly
system process GO:0003008 136 0.036
Human Mouse
positive regulation of multicellular organism growth GO:0040018 352 0.035
positive regulation of metabolic process GO:0009893 187 0.035
positive regulation of biosynthetic process GO:0009891 109 0.035
positive regulation of growth GO:0045927 369 0.034
Rat
response to abiotic stimulus GO:0009628 152 0.034
cell cell signaling GO:0007267 118 0.034
skeletal muscle organ development GO:0060538 3 0.034
fertilization GO:0009566 63 0.033
secretion GO:0046903 147 0.033
Mouse
regulation of phosphorus metabolic process GO:0051174 81 0.033
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.033
neuromuscular junction development GO:0007528 2 0.032
regulation of cell cycle GO:0051726 194 0.032
Rat Fly
positive regulation of developmental growth GO:0048639 354 0.031
Rat
posttranscriptional gene silencing GO:0016441 143 0.030
rrna processing GO:0006364 3 0.030
rrna metabolic process GO:0016072 3 0.030
cellular protein complex assembly GO:0043623 178 0.030
taxis GO:0042330 128 0.030
Fly
protein phosphorylation GO:0006468 85 0.029
positive regulation of protein metabolic process GO:0051247 45 0.029
carbohydrate derivative metabolic process GO:1901135 141 0.029
Mouse
protein complex assembly GO:0006461 186 0.029
cellular component morphogenesis GO:0032989 318 0.029
Human Mouse Rat Fly
rna localization GO:0006403 3 0.029
Fly
lipid metabolic process GO:0006629 77 0.028
regulation of locomotion GO:0040012 161 0.028
signal transduction by phosphorylation GO:0023014 31 0.028
Mouse
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.028
defense response GO:0006952 296 0.028
embryonic morphogenesis GO:0048598 152 0.027
carboxylic acid metabolic process GO:0019752 34 0.027
oocyte axis specification GO:0007309 2 0.027
Fly
nucleobase containing compound catabolic process GO:0034655 114 0.027
Mouse
organelle fission GO:0048285 363 0.027
response to other organism GO:0051707 101 0.027
peptidyl amino acid modification GO:0018193 58 0.027
guanosine containing compound metabolic process GO:1901068 49 0.027
Mouse
regulation of catabolic process GO:0009894 57 0.027
Mouse
regulation of cellular protein metabolic process GO:0032268 75 0.027
Fly
striated muscle cell differentiation GO:0051146 158 0.027
response to heat GO:0009408 50 0.026
nucleotide metabolic process GO:0009117 108 0.026
Mouse
meiotic cell cycle process GO:1903046 170 0.026
regulation of meiotic cell cycle GO:0051445 136 0.026
regulation of transport GO:0051049 91 0.026
Fly
response to biotic stimulus GO:0009607 101 0.026
regulation of protein metabolic process GO:0051246 81 0.026
Fly
spindle organization GO:0007051 92 0.026
engulfment of apoptotic cell GO:0043652 94 0.026
tube development GO:0035295 126 0.026
neuron projection guidance GO:0097485 82 0.025
Fly
response to external stimulus GO:0009605 289 0.025
Fly
regulation of organelle organization GO:0033043 164 0.025
regulation of cell development GO:0060284 49 0.025
Rat Fly
rna interference GO:0016246 137 0.025
meiotic chromosome segregation GO:0045132 139 0.025
regulation of mitotic cell cycle GO:0007346 76 0.024
Rat Fly
cell projection morphogenesis GO:0048858 148 0.024
Human Rat Fly
neuron development GO:0048666 199 0.024
Human Rat Fly
cell morphogenesis GO:0000902 163 0.024
Human Rat Fly
heterocycle catabolic process GO:0046700 119 0.024
Mouse
axonogenesis GO:0007409 102 0.024
Human Rat Fly
oocyte construction GO:0007308 2 0.024
Fly
cellular catabolic process GO:0044248 199 0.023
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.023
Human Rat Fly
phosphorylation GO:0016310 116 0.023
Mouse
positive regulation of cell migration GO:0030335 3 0.023
positive regulation of signaling GO:0023056 66 0.023
Mouse
proteolysis GO:0006508 61 0.023
neurological system process GO:0050877 53 0.023
Human Mouse
ribonucleoprotein complex assembly GO:0022618 4 0.022
neuron projection morphogenesis GO:0048812 114 0.022
Human Rat Fly
regulation of meiosis GO:0040020 94 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.022
guanosine containing compound catabolic process GO:1901069 48 0.022
Mouse
regulation of cell cycle process GO:0010564 145 0.022
Fly
regulation of canonical wnt signaling pathway GO:0060828 1 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
positive regulation of rna biosynthetic process GO:1902680 102 0.022
innate immune response GO:0045087 190 0.022
negative regulation of biosynthetic process GO:0009890 65 0.022
regulation of cell motility GO:2000145 57 0.021
regulation of protein targeting GO:1903533 3 0.021
actomyosin structure organization GO:0031032 154 0.021
negative regulation of neurogenesis GO:0050768 4 0.021
Rat
regeneration GO:0031099 4 0.021
cell type specific apoptotic process GO:0097285 4 0.021
digestive tract development GO:0048565 122 0.021
oxoacid metabolic process GO:0043436 47 0.021
regulation of lipid metabolic process GO:0019216 4 0.021
pattern specification process GO:0007389 59 0.021
Fly
regulation of multi organism process GO:0043900 69 0.021
regulation of protein import into nucleus GO:0042306 3 0.021
secretion by cell GO:0032940 138 0.021
Mouse
cellular response to chemical stimulus GO:0070887 129 0.021
Mouse
chromosome segregation GO:0007059 180 0.020
memory GO:0007613 3 0.020
regulation of molecular function GO:0065009 89 0.020
Mouse
response to organic substance GO:0010033 131 0.020
Mouse
cytokinesis GO:0000910 80 0.020
glycosyl compound metabolic process GO:1901657 100 0.020
Mouse
epithelial tube morphogenesis GO:0060562 1 0.019
organic acid metabolic process GO:0006082 47 0.019
single organism catabolic process GO:0044712 129 0.019
Mouse
posttranscriptional gene silencing by rna GO:0035194 143 0.019
muscle structure development GO:0061061 191 0.019
regulation of cellular component size GO:0032535 40 0.019
Rat
axon guidance GO:0007411 82 0.019
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.019
single organism biosynthetic process GO:0044711 91 0.019
regulation of cell migration GO:0030334 55 0.019
ribonucleoside catabolic process GO:0042454 77 0.019
Mouse
pronuclear migration GO:0035046 51 0.019
carbohydrate derivative catabolic process GO:1901136 82 0.019
Mouse
nitrogen compound transport GO:0071705 49 0.018
positive regulation of gene expression GO:0010628 112 0.018
membrane invagination GO:0010324 98 0.018
cellular component assembly involved in morphogenesis GO:0010927 183 0.018
Mouse Fly
regulation of protein localization GO:0032880 50 0.018
protein transport GO:0015031 45 0.018
Mouse Fly
regulation of catalytic activity GO:0050790 78 0.018
Mouse
er nucleus signaling pathway GO:0006984 66 0.018
gene silencing GO:0016458 143 0.018
regulation of synapse assembly GO:0051963 2 0.018
nucleoside metabolic process GO:0009116 99 0.018
Mouse
embryonic pattern specification GO:0009880 21 0.018
ion transport GO:0006811 113 0.018
myofibril assembly GO:0030239 154 0.018
digestive system development GO:0055123 122 0.018
muscle cell differentiation GO:0042692 171 0.018
nucleoside catabolic process GO:0009164 78 0.017
Mouse
cell morphogenesis involved in differentiation GO:0000904 112 0.017
Human Rat Fly
purine containing compound metabolic process GO:0072521 95 0.017
Mouse
axon development GO:0061564 163 0.017
Human Rat Fly
muscle cell development GO:0055001 158 0.017
nucleoside phosphate metabolic process GO:0006753 108 0.017
Mouse
positive regulation of catalytic activity GO:0043085 59 0.017
mapk cascade GO:0000165 31 0.017
Mouse
aromatic compound catabolic process GO:0019439 116 0.017
Mouse
bmp signaling pathway GO:0030509 3 0.017
Fly
single organism behavior GO:0044708 83 0.017
Human Mouse
cellular response to abiotic stimulus GO:0071214 4 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
single organism membrane organization GO:0044802 35 0.017
Mouse
positive regulation of protein transport GO:0051222 4 0.017
ribose phosphate metabolic process GO:0019693 99 0.016
Mouse
positive regulation of cellular component organization GO:0051130 34 0.016
Rat
establishment of mitotic spindle localization GO:0040001 41 0.016
collagen and cuticulin based cuticle development GO:0040002 99 0.016
organonitrogen compound catabolic process GO:1901565 90 0.016
Mouse
cellular macromolecule catabolic process GO:0044265 73 0.016
epithelium development GO:0060429 68 0.016
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.016
striated muscle myosin thick filament assembly GO:0071688 138 0.016
developmental cell growth GO:0048588 39 0.016
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.016
apoptotic cell clearance GO:0043277 111 0.016
striated muscle cell development GO:0055002 157 0.016
mitotic nuclear division GO:0007067 89 0.016
response to external biotic stimulus GO:0043207 101 0.016
negative regulation of cellular biosynthetic process GO:0031327 65 0.015
organophosphate metabolic process GO:0019637 125 0.015
Mouse
internal peptidyl lysine acetylation GO:0018393 3 0.015
nucleoside triphosphate catabolic process GO:0009143 72 0.015
Mouse
adult behavior GO:0030534 3 0.015
Human Mouse
negative regulation of rna metabolic process GO:0051253 53 0.015
cellular lipid metabolic process GO:0044255 40 0.015
cell part morphogenesis GO:0032990 152 0.015
Human Rat Fly
positive regulation of molecular function GO:0044093 61 0.015
single organism carbohydrate metabolic process GO:0044723 29 0.015
negative regulation of response to external stimulus GO:0032102 3 0.015
regulation of bmp signaling pathway GO:0030510 3 0.015
Fly
nucleoside triphosphate metabolic process GO:0009141 87 0.015
Mouse
monosaccharide metabolic process GO:0005996 2 0.015
cuticle development GO:0042335 100 0.015
negative regulation of nucleic acid templated transcription GO:1903507 53 0.015
response to temperature stimulus GO:0009266 66 0.015
response to bacterium GO:0009617 86 0.015
establishment of spindle localization GO:0051293 51 0.015
ribonucleoside triphosphate catabolic process GO:0009203 72 0.015
Mouse
protein localization to organelle GO:0033365 37 0.015
Fly
positive regulation of phosphate metabolic process GO:0045937 56 0.015
regionalization GO:0003002 31 0.015
Fly
oxidation reduction process GO:0055114 59 0.014
myosin filament organization GO:0031033 138 0.014
organonitrogen compound biosynthetic process GO:1901566 44 0.014
negative regulation of signaling GO:0023057 61 0.014
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 87 0.014
Mouse
nucleobase containing small molecule metabolic process GO:0055086 115 0.014
Mouse
nucleus localization GO:0051647 55 0.014
regulation of organ morphogenesis GO:2000027 4 0.014
positive regulation of cell cycle GO:0045787 55 0.014
Rat
positive regulation of neurogenesis GO:0050769 4 0.014
Rat
negative regulation of cell communication GO:0010648 61 0.014
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.014
Mouse
positive regulation of locomotion GO:0040017 42 0.014
endosomal transport GO:0016197 26 0.014
cognition GO:0050890 27 0.014
Mouse
tube morphogenesis GO:0035239 79 0.014
establishment of protein localization to membrane GO:0090150 3 0.014
digestive tract morphogenesis GO:0048546 76 0.014
positive regulation of nematode larval development GO:0061063 54 0.013
regulation of wnt signaling pathway GO:0030111 9 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.013
cellular response to inorganic substance GO:0071241 3 0.013
nucleotide catabolic process GO:0009166 77 0.013
Mouse
positive regulation of catabolic process GO:0009896 38 0.013
amine metabolic process GO:0009308 15 0.013
negative regulation of signal transduction GO:0009968 60 0.013
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of cellular localization GO:0060341 42 0.013
Fly
monocarboxylic acid metabolic process GO:0032787 22 0.013
myosin filament assembly GO:0031034 138 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.013
Mouse
modification dependent protein catabolic process GO:0019941 32 0.013
learning or memory GO:0007611 27 0.013
Mouse
regulation of muscle cell differentiation GO:0051147 1 0.013
spindle localization GO:0051653 51 0.013
synaptic vesicle localization GO:0097479 22 0.013
cell maturation GO:0048469 26 0.013
Fly
male sex differentiation GO:0046661 86 0.013
negative regulation of transcription dna templated GO:0045892 53 0.012
ribonucleoside metabolic process GO:0009119 98 0.012
Mouse
negative regulation of cellular metabolic process GO:0031324 95 0.012
Mouse
cell substrate adhesion GO:0031589 1 0.012
cellular amine metabolic process GO:0044106 15 0.012
positive regulation of cellular protein catabolic process GO:1903364 3 0.012
purine nucleoside triphosphate catabolic process GO:0009146 72 0.012
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.012
regulation of behavior GO:0050795 97 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
regulation of protein stability GO:0031647 3 0.012
modification dependent macromolecule catabolic process GO:0043632 32 0.012
regulation of neurogenesis GO:0050767 40 0.012
Rat Fly
muscle fiber development GO:0048747 2 0.012
purine containing compound catabolic process GO:0072523 75 0.012
Mouse
regulation of epithelial cell differentiation GO:0030856 4 0.012
regulation of anatomical structure morphogenesis GO:0022603 51 0.012
Rat Fly
regulation of cell proliferation GO:0042127 105 0.012
positive regulation of intracellular protein transport GO:0090316 2 0.012
cell projection organization GO:0030030 231 0.012
Human Rat Fly
regulation of phosphate metabolic process GO:0019220 81 0.012
Mouse
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
regulation of epithelial cell proliferation GO:0050678 1 0.011
purine ribonucleoside metabolic process GO:0046128 92 0.011
Mouse
positive regulation of vulval development GO:0040026 52 0.011
purine nucleoside catabolic process GO:0006152 75 0.011
Mouse
negative regulation of rna biosynthetic process GO:1902679 53 0.011
regulation of apoptotic signaling pathway GO:2001233 1 0.011
inductive cell migration GO:0040039 145 0.011
adult locomotory behavior GO:0008344 1 0.011
Human Mouse
regulation of stem cell differentiation GO:2000736 1 0.011
gtp metabolic process GO:0046039 46 0.011
Mouse
regulation of phosphorylation GO:0042325 45 0.011
Mouse
regulation of cellular component biogenesis GO:0044087 26 0.011
positive regulation of transport GO:0051050 32 0.011
Fly
protein oligomerization GO:0051259 4 0.011
carbohydrate metabolic process GO:0005975 34 0.011
cellular response to metal ion GO:0071248 3 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
peptidyl serine modification GO:0018209 20 0.011
cellular ketone metabolic process GO:0042180 14 0.011
cellular nitrogen compound catabolic process GO:0044270 119 0.011
Mouse
defense response to gram negative bacterium GO:0050829 64 0.011
regulation of cellular component movement GO:0051270 62 0.011
Fly
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
Mouse
g1 s transition of mitotic cell cycle GO:0000082 2 0.011
neuron projection development GO:0031175 187 0.011
Human Rat Fly
regulation of response to wounding GO:1903034 1 0.010
lipid biosynthetic process GO:0008610 28 0.010

lis-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.015