Caenorhabditis elegans

142 known processes

hlh-3 (CELE_T24B8.6)

Protein HLH-3

hlh-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development GO:0009790 3052 0.543
Human Mouse Fly
cell fate commitment GO:0045165 139 0.394
Human Mouse Worm
post embryonic development GO:0009791 2152 0.298
Worm
locomotion GO:0040011 1634 0.252
nucleobase containing compound metabolic process GO:0006139 406 0.245
rna biosynthetic process GO:0032774 169 0.229
regulation of developmental process GO:0050793 684 0.197
organ development GO:0048513 1102 0.193
Human Zebrafish Mouse Fly
developmental process involved in reproduction GO:0003006 1165 0.191
Human Mouse Fly
regulation of gene expression GO:0010468 366 0.188
Human Zebrafish Mouse Rat Worm Fly
multicellular organism reproduction GO:0032504 819 0.178
sex differentiation GO:0007548 909 0.177
embryo development ending in birth or egg hatching GO:0009792 2992 0.176
Human Mouse
single organism reproductive process GO:0044702 1196 0.174
Human Mouse
gene expression GO:0010467 412 0.164
multicellular organismal reproductive process GO:0048609 815 0.161
organelle organization GO:0006996 783 0.159
Fly
negative regulation of biological process GO:0048519 567 0.155
Human Zebrafish Mouse Rat Fly
cell development GO:0048468 696 0.155
multi organism reproductive process GO:0044703 867 0.153
reproductive structure development GO:0048608 850 0.150
Human Mouse
regulation of multicellular organismal process GO:0051239 726 0.148
transcription from rna polymerase ii promoter GO:0006366 149 0.142
cell motility GO:0048870 313 0.142
Mouse Worm
rna metabolic process GO:0016070 228 0.141
anatomical structure formation involved in morphogenesis GO:0048646 250 0.137
Zebrafish
nucleic acid templated transcription GO:0097659 169 0.136
body morphogenesis GO:0010171 620 0.135
Worm
cellular nitrogen compound biosynthetic process GO:0044271 192 0.133
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.130
Human Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 247 0.130
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.130
Human Zebrafish Mouse Rat Worm Fly
organic substance biosynthetic process GO:1901576 323 0.130
aging GO:0007568 812 0.125
Worm
receptor mediated endocytosis GO:0006898 715 0.125
multicellular organismal aging GO:0010259 812 0.124
Worm
negative regulation of metabolic process GO:0009892 240 0.124
Human Zebrafish
gonad development GO:0008406 840 0.123
regulation of primary metabolic process GO:0080090 292 0.122
Human Zebrafish Mouse Rat Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 222 0.117
Human Zebrafish Mouse Rat Worm Fly
endocytosis GO:0006897 819 0.116
regulation of multicellular organismal development GO:2000026 317 0.115
regulation of macromolecule biosynthetic process GO:0010556 189 0.114
Human Zebrafish Mouse Rat Worm Fly
positive regulation of nucleic acid templated transcription GO:1903508 102 0.112
Human Zebrafish Mouse Fly
reproductive system development GO:0061458 850 0.108
Human Mouse
heterocycle biosynthetic process GO:0018130 187 0.105
regulation of transcription dna templated GO:0006355 164 0.104
Human Zebrafish Mouse Rat Worm Fly
post embryonic organ development GO:0048569 336 0.104
establishment of localization GO:0051234 1171 0.101
determination of adult lifespan GO:0008340 812 0.100
Worm
hermaphrodite genitalia development GO:0040035 734 0.099
nucleic acid metabolic process GO:0090304 299 0.097
negative regulation of cellular process GO:0048523 239 0.096
Human Mouse Rat Fly
cellular biosynthetic process GO:0044249 315 0.096
death GO:0016265 547 0.095
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.094
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.094
Human Mouse Worm Fly
development of primary sexual characteristics GO:0045137 840 0.094
macromolecule localization GO:0033036 771 0.093
organic cyclic compound biosynthetic process GO:1901362 195 0.092
multi organism behavior GO:0051705 389 0.091
multicellular organismal reproductive behavior GO:0033057 384 0.091
regulation of nucleic acid templated transcription GO:1903506 165 0.090
Human Zebrafish Mouse Rat Worm Fly
regulation of metabolic process GO:0019222 478 0.090
Human Zebrafish Mouse Rat Worm Fly
multi multicellular organism process GO:0044706 390 0.089
regulation of rna metabolic process GO:0051252 173 0.089
Human Zebrafish Mouse Rat Worm Fly
regulation of macromolecule metabolic process GO:0060255 421 0.089
Human Zebrafish Mouse Rat Worm Fly
cell cycle GO:0007049 526 0.087
Mouse Fly
cell migration GO:0016477 306 0.086
Mouse Worm
aromatic compound biosynthetic process GO:0019438 192 0.085
regulation of rna biosynthetic process GO:2001141 165 0.085
Human Zebrafish Mouse Rat Worm Fly
vulval development GO:0040025 333 0.085
positive regulation of rna biosynthetic process GO:1902680 102 0.083
Human Zebrafish Mouse Fly
reproductive behavior GO:0019098 387 0.082
oviposition GO:0018991 364 0.081
cell death GO:0008219 547 0.080
transport GO:0006810 1093 0.079
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.078
Human Zebrafish Mouse Rat Worm Fly
regulation of cellular metabolic process GO:0031323 305 0.078
Human Zebrafish Mouse Rat Worm Fly
single organism localization GO:1902578 518 0.078
positive regulation of growth GO:0045927 369 0.078
Worm
regulation of nematode larval development GO:0061062 260 0.075
sexual reproduction GO:0019953 546 0.073
multi organism reproductive behavior GO:0044705 387 0.069
regulation of cellular biosynthetic process GO:0031326 189 0.069
Human Zebrafish Mouse Rat Worm Fly
negative regulation of transcription dna templated GO:0045892 53 0.069
Human
positive regulation of cellular biosynthetic process GO:0031328 109 0.068
Human Zebrafish Mouse Fly
growth GO:0040007 562 0.068
negative regulation of macromolecule metabolic process GO:0010605 229 0.068
Human Zebrafish
regulation of biological quality GO:0065008 741 0.067
maintenance of location GO:0051235 580 0.067
lipid localization GO:0010876 573 0.067
positive regulation of cellular metabolic process GO:0031325 178 0.066
Human Zebrafish Mouse Fly
positive regulation of multicellular organismal process GO:0051240 417 0.066
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.066
Human Zebrafish Mouse Fly
regulation of biosynthetic process GO:0009889 189 0.065
Human Zebrafish Mouse Rat Worm Fly
lipid storage GO:0019915 565 0.065
cellular component morphogenesis GO:0032989 318 0.065
macromolecule biosynthetic process GO:0009059 250 0.064
mesodermal cell differentiation GO:0048333 15 0.064
protein metabolic process GO:0019538 422 0.062
positive regulation of developmental process GO:0051094 408 0.062
Mouse
negative regulation of multicellular organismal process GO:0051241 236 0.062
Human Rat
programmed cell death GO:0012501 500 0.062
single organism signaling GO:0044700 401 0.061
Human Mouse
localization of cell GO:0051674 313 0.061
Mouse Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.061
Human
embryonic morphogenesis GO:0048598 152 0.060
Fly
genitalia development GO:0048806 741 0.059
cellular component movement GO:0006928 388 0.059
regulation of vulval development GO:0040028 248 0.058
nucleobase containing compound biosynthetic process GO:0034654 184 0.057
regulation of growth GO:0040008 409 0.057
biosynthetic process GO:0009058 323 0.057
gamete generation GO:0007276 461 0.056
behavior GO:0007610 527 0.055
cellular component assembly GO:0022607 293 0.055
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.055
Human Zebrafish Mouse Fly
negative regulation of post embryonic development GO:0048581 208 0.054
vesicle mediated transport GO:0016192 852 0.053
negative regulation of gene expression GO:0010629 217 0.053
Human Zebrafish
signal transduction GO:0007165 317 0.052
Human Mouse
regulation of developmental growth GO:0048638 389 0.052
cell cycle process GO:0022402 482 0.052
Fly
regulation of locomotion GO:0040012 161 0.051
positive regulation of biosynthetic process GO:0009891 109 0.051
Human Zebrafish Mouse Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.050
defense response GO:0006952 296 0.049
epithelium development GO:0060429 68 0.049
Zebrafish Mouse Fly
single organism organelle organization GO:1902589 501 0.048
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.048
regulation of multicellular organism growth GO:0040014 373 0.047
cellular component biogenesis GO:0044085 297 0.046
macromolecular complex subunit organization GO:0043933 320 0.045
multicellular organism growth GO:0035264 385 0.045
Worm
cellular localization GO:0051641 360 0.044
negative regulation of nucleic acid templated transcription GO:1903507 53 0.044
Human
cell division GO:0051301 262 0.043
Worm Fly
meiotic nuclear division GO:0007126 300 0.043
single organism transport GO:0044765 447 0.043
regulation of cellular component organization GO:0051128 248 0.043
cellular protein metabolic process GO:0044267 279 0.043
transcription dna templated GO:0006351 168 0.042
negative regulation of vulval development GO:0040027 206 0.041
negative regulation of developmental process GO:0051093 227 0.041
Human Mouse Rat
regulation of cell cycle GO:0051726 194 0.041
Mouse Fly
digestive tract development GO:0048565 122 0.040
Mouse Worm Fly
positive regulation of cellular process GO:0048522 332 0.040
regulation of post embryonic development GO:0048580 260 0.040
digestive system development GO:0055123 122 0.040
Mouse Worm Fly
positive regulation of transcription dna templated GO:0045893 102 0.040
Human Zebrafish Mouse Fly
cellular response to chemical stimulus GO:0070887 129 0.040
developmental growth GO:0048589 412 0.039
macromolecule modification GO:0043412 218 0.039
negative regulation of cellular metabolic process GO:0031324 95 0.039
Human
muscle structure development GO:0061061 191 0.038
regulation of signaling GO:0023051 172 0.038
Mouse
striated muscle cell differentiation GO:0051146 158 0.038
meiotic cell cycle GO:0051321 335 0.038
gastrulation GO:0007369 58 0.038
tissue morphogenesis GO:0048729 65 0.037
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 63 0.037
Human
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.037
positive regulation of metabolic process GO:0009893 187 0.037
Human Zebrafish Mouse Fly
positive regulation of developmental growth GO:0048639 354 0.036
cellular response to organic substance GO:0071310 119 0.035
germ cell development GO:0007281 351 0.035
innate immune response GO:0045087 190 0.035
digestive tract morphogenesis GO:0048546 76 0.035
Fly
negative regulation of nematode larval development GO:0061064 208 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.034
Human Zebrafish Mouse Fly
response to chemical GO:0042221 356 0.034
cell type specific apoptotic process GO:0097285 4 0.034
Mouse
response to organic substance GO:0010033 131 0.034
Human
response to external stimulus GO:0009605 289 0.034
tube morphogenesis GO:0035239 79 0.034
Fly
head development GO:0060322 1 0.034
Human Zebrafish Mouse
female gamete generation GO:0007292 254 0.034
protein modification process GO:0036211 207 0.034
dauer larval development GO:0040024 92 0.033
catabolic process GO:0009056 318 0.033
immune response GO:0006955 192 0.033
Fly
small molecule metabolic process GO:0044281 186 0.033
macromolecular complex assembly GO:0065003 193 0.033
neurogenesis GO:0022008 236 0.032
organelle fission GO:0048285 363 0.032
Fly
muscle cell differentiation GO:0042692 171 0.032
cellular response to abiotic stimulus GO:0071214 4 0.031
response to abiotic stimulus GO:0009628 152 0.031
Human
pattern specification process GO:0007389 59 0.031
Mouse
tube development GO:0035295 126 0.031
Mouse Worm Fly
negative regulation of rna biosynthetic process GO:1902679 53 0.031
Human
regulation of localization GO:0032879 194 0.031
cytoskeleton organization GO:0007010 339 0.031
actomyosin structure organization GO:0031032 154 0.031
organonitrogen compound metabolic process GO:1901564 151 0.031
Fly
cellular macromolecular complex assembly GO:0034622 184 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.030
Human
negative regulation of cellular biosynthetic process GO:0031327 65 0.030
Human
negative regulation of biosynthetic process GO:0009890 65 0.029
Human
tissue development GO:0009888 112 0.029
Human Zebrafish Mouse Fly
actin filament based process GO:0030029 191 0.029
neuron recognition GO:0008038 83 0.029
cellular component assembly involved in morphogenesis GO:0010927 183 0.029
neuron differentiation GO:0030182 217 0.029
protein complex assembly GO:0006461 186 0.028
defense response to other organism GO:0098542 100 0.028
protein complex subunit organization GO:0071822 280 0.028
regulation of organ morphogenesis GO:2000027 4 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 3 0.028
regulation of organelle organization GO:0033043 164 0.028
Fly
oogenesis GO:0048477 229 0.028
establishment of localization in cell GO:0051649 318 0.027
protein localization GO:0008104 205 0.027
cuticle development GO:0042335 100 0.027
male sex differentiation GO:0046661 86 0.027
positive regulation of signaling GO:0023056 66 0.027
Mouse
mesodermal cell fate specification GO:0007501 13 0.027
macromolecule catabolic process GO:0009057 202 0.027
sensory organ morphogenesis GO:0090596 2 0.027
Zebrafish
response to wounding GO:0009611 4 0.027
Zebrafish
myofibril assembly GO:0030239 154 0.026
organic substance catabolic process GO:1901575 294 0.026
apoptotic process GO:0006915 478 0.026
Human Mouse Fly
mesoderm morphogenesis GO:0048332 24 0.026
cell proliferation GO:0008283 116 0.026
Mouse Rat Fly
cellular protein modification process GO:0006464 207 0.026
regulation of meiosis GO:0040020 94 0.025
cellular response to stress GO:0033554 162 0.025
positive regulation of rna metabolic process GO:0051254 103 0.025
Human Zebrafish Mouse Fly
muscle tissue development GO:0060537 1 0.025
actin cytoskeleton organization GO:0030036 184 0.025
cell projection organization GO:0030030 231 0.025
regulation of response to stimulus GO:0048583 243 0.024
regulation of cell cycle process GO:0010564 145 0.024
Fly
organelle assembly GO:0070925 214 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.024
Human
cell cell signaling GO:0007267 118 0.024
inductive cell migration GO:0040039 145 0.024
muscle cell development GO:0055001 158 0.024
phosphate containing compound metabolic process GO:0006796 232 0.023
phosphorus metabolic process GO:0006793 232 0.023
chemotaxis GO:0006935 120 0.023
signaling GO:0023052 401 0.023
Human Mouse
molting cycle GO:0042303 281 0.023
protein complex biogenesis GO:0070271 186 0.023
regulation of meiotic cell cycle GO:0051445 136 0.023
muscle organ morphogenesis GO:0048644 4 0.022
regulation of cell division GO:0051302 142 0.022
Worm Fly
regulation of cell communication GO:0010646 176 0.022
Mouse
regulation of neuron differentiation GO:0045664 40 0.021
positive regulation of gene expression GO:0010628 112 0.021
Human Zebrafish Mouse Fly
organ morphogenesis GO:0009887 67 0.021
Zebrafish Fly
response to other organism GO:0051707 101 0.021
Fly
mesoderm development GO:0007498 27 0.021
striated muscle myosin thick filament assembly GO:0071688 138 0.021
positive regulation of neurogenesis GO:0050769 4 0.021
Mouse
organic acid metabolic process GO:0006082 47 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.021
secretion GO:0046903 147 0.021
positive regulation of macromolecule metabolic process GO:0010604 149 0.021
Human Zebrafish Mouse Fly
cell recognition GO:0008037 85 0.020
male anatomical structure morphogenesis GO:0090598 78 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.020
striated muscle cell development GO:0055002 157 0.020
myosin filament assembly GO:0031034 138 0.020
cellular catabolic process GO:0044248 199 0.019
single organism catabolic process GO:0044712 129 0.019
response to biotic stimulus GO:0009607 101 0.019
Fly
oxoacid metabolic process GO:0043436 47 0.019
myosin filament organization GO:0031033 138 0.019
positive regulation of molecular function GO:0044093 61 0.018
enzyme linked receptor protein signaling pathway GO:0007167 50 0.018
regulation of molecular function GO:0065009 89 0.017
regulation of cytoplasmic transport GO:1903649 3 0.017
cellular response to endogenous stimulus GO:0071495 32 0.017
negative regulation of rna metabolic process GO:0051253 53 0.017
Human
intracellular receptor signaling pathway GO:0030522 2 0.017
nervous system development GO:0007399 253 0.017
collagen and cuticulin based cuticle development GO:0040002 99 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
neuron projection development GO:0031175 187 0.016
defense response to bacterium GO:0042742 86 0.016
axonal fasciculation GO:0007413 79 0.016
skeletal muscle organ development GO:0060538 3 0.016
nematode male tail tip morphogenesis GO:0045138 77 0.016
cell part morphogenesis GO:0032990 152 0.016
homeostatic process GO:0042592 51 0.016
carboxylic acid metabolic process GO:0019752 34 0.015
regulation of response to wounding GO:1903034 1 0.015
organic substance transport GO:0071702 113 0.015
response to external biotic stimulus GO:0043207 101 0.015
Fly
positive regulation of neuron differentiation GO:0045666 4 0.015
Mouse
generation of neurons GO:0048699 235 0.015
regulation of signal transduction GO:0009966 135 0.015
Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.014
response to bacterium GO:0009617 86 0.014
regulation of apoptotic signaling pathway GO:2001233 1 0.014
membrane organization GO:0061024 135 0.014
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.014
cellular protein complex assembly GO:0043623 178 0.014
neuron fate specification GO:0048665 8 0.014
Mouse
synaptic transmission GO:0007268 106 0.014
carbohydrate derivative metabolic process GO:1901135 141 0.014
regulation of cell proliferation GO:0042127 105 0.014
Mouse Rat
protein catabolic process GO:0030163 162 0.014
cellular response to hormone stimulus GO:0032870 14 0.014
system process GO:0003008 136 0.014
cellular ketone metabolic process GO:0042180 14 0.014
epithelial tube morphogenesis GO:0060562 1 0.013
Fly
detection of external stimulus GO:0009581 4 0.013
regulation of lipid metabolic process GO:0019216 4 0.013
neuron development GO:0048666 199 0.013
organonitrogen compound biosynthetic process GO:1901566 44 0.013
Fly
secretion by cell GO:0032940 138 0.013
rna localization GO:0006403 3 0.013
gene silencing GO:0016458 143 0.013
negative regulation of response to stimulus GO:0048585 73 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
cellular amino acid metabolic process GO:0006520 15 0.012
regulation of cell differentiation GO:0045595 81 0.012
nuclear migration GO:0007097 54 0.012
ribonucleoprotein complex assembly GO:0022618 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
positive regulation of cell cycle GO:0045787 55 0.012
Mouse
endodermal cell fate determination GO:0007493 2 0.012
regulation of synaptic transmission GO:0050804 34 0.012
nitrogen compound transport GO:0071705 49 0.012
aromatic compound catabolic process GO:0019439 116 0.012
single organism biosynthetic process GO:0044711 91 0.012
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacterium GO:1902097 4 0.012
positive regulation of vulval development GO:0040026 52 0.012
cellular response to oxygen containing compound GO:1901701 21 0.012
organelle localization GO:0051640 127 0.012
cellular nitrogen compound catabolic process GO:0044270 119 0.012
internal peptidyl lysine acetylation GO:0018393 3 0.012
gene silencing by rna GO:0031047 143 0.012
posttranscriptional gene silencing GO:0016441 143 0.012
microtubule based process GO:0007017 182 0.011
negative regulation of neuron differentiation GO:0045665 4 0.011
Human
lipid metabolic process GO:0006629 77 0.011
response to acid chemical GO:0001101 4 0.011
Human
positive regulation of intracellular transport GO:0032388 2 0.011
regulation of phosphate metabolic process GO:0019220 81 0.011
positive regulation of synaptic transmission GO:0050806 24 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cytokinesis GO:0000910 80 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
Mouse
cellular amine metabolic process GO:0044106 15 0.011
defense response to gram negative bacterium GO:0050829 64 0.011
response to peptide hormone GO:0043434 14 0.011
organic cyclic compound catabolic process GO:1901361 119 0.011
phosphorylation GO:0016310 116 0.011
adult behavior GO:0030534 3 0.011
single organism behavior GO:0044708 83 0.011
calcium mediated signaling GO:0019722 3 0.011
protein oligomerization GO:0051259 4 0.011
intracellular signal transduction GO:0035556 96 0.011
regulation of protein stability GO:0031647 3 0.011
negative regulation of cell cycle GO:0045786 53 0.011
Fly
neuroblast fate specification GO:0014018 4 0.011
Worm
neuron projection guidance GO:0097485 82 0.011
positive regulation of cell communication GO:0010647 69 0.011
Mouse
epithelial cell proliferation GO:0050673 1 0.010
Fly
nucleus localization GO:0051647 55 0.010
negative regulation of signal transduction GO:0009968 60 0.010
hormone transport GO:0009914 2 0.010
rna interference GO:0016246 137 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.010
neuromuscular junction development GO:0007528 2 0.010
taxis GO:0042330 128 0.010
positive regulation of protein transport GO:0051222 4 0.010
amine metabolic process GO:0009308 15 0.010
purine nucleotide catabolic process GO:0006195 75 0.010

hlh-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.010