Caenorhabditis elegans

11 known processes

mlh-1 (CELE_T28A8.7)

Protein MLH-1

mlh-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle organization GO:0006996 783 0.590
Zebrafish Mouse
post embryonic organ development GO:0048569 336 0.335
developmental process involved in reproduction GO:0003006 1165 0.335
Mouse
death GO:0016265 547 0.322
Mouse
embryo development ending in birth or egg hatching GO:0009792 2992 0.292
negative regulation of biological process GO:0048519 567 0.263
Mouse
regulation of cellular metabolic process GO:0031323 305 0.252
Mouse
post embryonic development GO:0009791 2152 0.250
organ development GO:0048513 1102 0.236
embryo development GO:0009790 3052 0.219
gonad development GO:0008406 840 0.210
locomotion GO:0040011 1634 0.204
gene expression GO:0010467 412 0.189
Mouse
sex differentiation GO:0007548 909 0.183
regulation of primary metabolic process GO:0080090 292 0.177
Mouse
response to endoplasmic reticulum stress GO:0034976 71 0.152
rna metabolic process GO:0016070 228 0.140
Mouse
cell cycle process GO:0022402 482 0.139
Zebrafish Mouse
programmed cell death GO:0012501 500 0.134
Mouse
single organism organelle organization GO:1902589 501 0.127
Zebrafish Mouse
reproductive structure development GO:0048608 850 0.125
negative regulation of cellular process GO:0048523 239 0.121
Mouse
single organism reproductive process GO:0044702 1196 0.121
Zebrafish Mouse
regulation of metabolic process GO:0019222 478 0.117
Mouse
organic substance biosynthetic process GO:1901576 323 0.115
multi organism reproductive process GO:0044703 867 0.114
Zebrafish Mouse
positive regulation of macromolecule metabolic process GO:0010604 149 0.107
response to biotic stimulus GO:0009607 101 0.106
reproductive system development GO:0061458 850 0.099
negative regulation of nematode larval development GO:0061064 208 0.095
cellular catabolic process GO:0044248 199 0.095
Mouse
response to other organism GO:0051707 101 0.089
macromolecular complex subunit organization GO:0043933 320 0.088
Mouse
macromolecule modification GO:0043412 218 0.087
response to external biotic stimulus GO:0043207 101 0.085
organelle fission GO:0048285 363 0.083
Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 406 0.083
Human Zebrafish Mouse
defense response GO:0006952 296 0.079
head development GO:0060322 1 0.079
regulation of biological quality GO:0065008 741 0.079
regulation of vulval development GO:0040028 248 0.077
regulation of multicellular organismal process GO:0051239 726 0.075
cell development GO:0048468 696 0.074
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 192 0.073
regulation of developmental process GO:0050793 684 0.070
macromolecule localization GO:0033036 771 0.069
protein metabolic process GO:0019538 422 0.068
cellular protein modification process GO:0006464 207 0.068
macromolecule biosynthetic process GO:0009059 250 0.065
vulval development GO:0040025 333 0.065
protein modification process GO:0036211 207 0.065
chromatin organization GO:0006325 32 0.064
lipid localization GO:0010876 573 0.063
lipid storage GO:0019915 565 0.063
aromatic compound biosynthetic process GO:0019438 192 0.063
negative regulation of multicellular organismal process GO:0051241 236 0.063
multicellular organismal reproductive process GO:0048609 815 0.060
Zebrafish Mouse
maintenance of location GO:0051235 580 0.059
negative regulation of metabolic process GO:0009892 240 0.059
Mouse
cell cycle GO:0007049 526 0.058
Zebrafish Mouse
striated muscle cell differentiation GO:0051146 158 0.057
response to organic substance GO:0010033 131 0.056
regulation of multicellular organismal development GO:2000026 317 0.056
nucleic acid metabolic process GO:0090304 299 0.055
Human Zebrafish Mouse
biosynthetic process GO:0009058 323 0.055
regulation of nematode larval development GO:0061062 260 0.055
regulation of cell cycle GO:0051726 194 0.053
negative regulation of post embryonic development GO:0048581 208 0.053
response to external stimulus GO:0009605 289 0.052
cellular component assembly GO:0022607 293 0.052
Zebrafish Mouse
cellular protein metabolic process GO:0044267 279 0.051
gamete generation GO:0007276 461 0.051
Zebrafish Mouse
muscle structure development GO:0061061 191 0.050
actin filament based process GO:0030029 191 0.049
cell death GO:0008219 547 0.049
Mouse
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.047
Mouse
regulation of catalytic activity GO:0050790 78 0.047
organonitrogen compound metabolic process GO:1901564 151 0.047
aging GO:0007568 812 0.046
multicellular organismal aging GO:0010259 812 0.045
apoptotic process GO:0006915 478 0.044
Mouse
body morphogenesis GO:0010171 620 0.044
regulation of molecular function GO:0065009 89 0.043
innate immune response GO:0045087 190 0.043
gene silencing by rna GO:0031047 143 0.043
positive regulation of cellular process GO:0048522 332 0.043
organic substance catabolic process GO:1901575 294 0.043
Mouse
regulation of post embryonic development GO:0048580 260 0.042
catabolic process GO:0009056 318 0.042
Mouse
cellular biosynthetic process GO:0044249 315 0.039
regulation of cellular component organization GO:0051128 248 0.039
positive regulation of metabolic process GO:0009893 187 0.039
behavior GO:0007610 527 0.038
regulation of biosynthetic process GO:0009889 189 0.038
actin cytoskeleton organization GO:0030036 184 0.038
positive regulation of catalytic activity GO:0043085 59 0.037
protein catabolic process GO:0030163 162 0.037
determination of adult lifespan GO:0008340 812 0.036
heterocycle biosynthetic process GO:0018130 187 0.035
nucleobase containing compound biosynthetic process GO:0034654 184 0.035
positive regulation of molecular function GO:0044093 61 0.035
cellular component morphogenesis GO:0032989 318 0.035
organism emergence from protective structure GO:0071684 48 0.034
negative regulation of developmental process GO:0051093 227 0.034
cellular response to chemical stimulus GO:0070887 129 0.033
negative regulation of vulval development GO:0040027 206 0.032
regulation of nitrogen compound metabolic process GO:0051171 222 0.032
Mouse
regulation of macromolecule metabolic process GO:0060255 421 0.032
Mouse
macromolecule catabolic process GO:0009057 202 0.032
Mouse
negative regulation of cellular metabolic process GO:0031324 95 0.031
Mouse
defense response to other organism GO:0098542 100 0.031
carbohydrate derivative metabolic process GO:1901135 141 0.029
anatomical structure formation involved in morphogenesis GO:0048646 250 0.029
phosphate containing compound metabolic process GO:0006796 232 0.028
growth GO:0040007 562 0.028
microtubule based process GO:0007017 182 0.027
Mouse
protein complex biogenesis GO:0070271 186 0.027
Mouse
phosphorylation GO:0016310 116 0.027
cell type specific apoptotic process GO:0097285 4 0.026
cytoskeleton organization GO:0007010 339 0.026
Mouse
neurogenesis GO:0022008 236 0.026
negative regulation of macromolecule metabolic process GO:0010605 229 0.026
Mouse
transport GO:0006810 1093 0.026
response to bacterium GO:0009617 86 0.026
vesicle mediated transport GO:0016192 852 0.025
regulation of phosphorus metabolic process GO:0051174 81 0.025
organic cyclic compound catabolic process GO:1901361 119 0.025
Mouse
dna metabolic process GO:0006259 74 0.025
Human Zebrafish Mouse
germ cell development GO:0007281 351 0.024
Mouse
regulation of gene expression epigenetic GO:0040029 163 0.024
sexual reproduction GO:0019953 546 0.024
Zebrafish Mouse
regulation of phosphate metabolic process GO:0019220 81 0.024
single organism signaling GO:0044700 401 0.024
Mouse
regulation of growth GO:0040008 409 0.023
multicellular organism growth GO:0035264 385 0.023
regulation of apoptotic signaling pathway GO:2001233 1 0.023
regulation of protein metabolic process GO:0051246 81 0.022
immune response GO:0006955 192 0.022
Mouse
regulation of phosphorylation GO:0042325 45 0.022
meiotic chromosome segregation GO:0045132 139 0.022
Zebrafish Mouse
posttranscriptional regulation of gene expression GO:0010608 166 0.022
regulation of developmental growth GO:0048638 389 0.021
cell motility GO:0048870 313 0.021
nucleobase containing compound catabolic process GO:0034655 114 0.021
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.021
regulation of transferase activity GO:0051338 31 0.021
cellular macromolecule biosynthetic process GO:0034645 247 0.021
cellular component movement GO:0006928 388 0.021
multicellular organism reproduction GO:0032504 819 0.021
Zebrafish Mouse
hatching GO:0035188 48 0.020
pigment metabolic process GO:0042440 2 0.020
localization of cell GO:0051674 313 0.020
rho protein signal transduction GO:0007266 2 0.020
reproductive behavior GO:0019098 387 0.020
transcription dna templated GO:0006351 168 0.019
multi multicellular organism process GO:0044706 390 0.019
regulation of multicellular organism growth GO:0040014 373 0.019
positive regulation of multicellular organismal process GO:0051240 417 0.019
dauer larval development GO:0040024 92 0.018
hermaphrodite genitalia development GO:0040035 734 0.018
response to chemical GO:0042221 356 0.018
cellular response to organic substance GO:0071310 119 0.017
secretion GO:0046903 147 0.017
negative regulation of signal transduction GO:0009968 60 0.017
rna biosynthetic process GO:0032774 169 0.017
cell migration GO:0016477 306 0.017
neuron projection development GO:0031175 187 0.017
cellular component biogenesis GO:0044085 297 0.017
Zebrafish Mouse
cellular macromolecule catabolic process GO:0044265 73 0.016
Mouse
genitalia development GO:0048806 741 0.016
mitotic g2 m transition checkpoint GO:0044818 1 0.016
positive regulation of growth GO:0045927 369 0.016
protein complex assembly GO:0006461 186 0.016
Mouse
myosin filament assembly GO:0031034 138 0.016
rna interference GO:0016246 137 0.016
response to unfolded protein GO:0006986 71 0.016
negative regulation of gene expression GO:0010629 217 0.016
multi organism behavior GO:0051705 389 0.016
cell proliferation GO:0008283 116 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.016
Mouse
regeneration GO:0031099 4 0.016
regulation of cell cycle process GO:0010564 145 0.015
multi organism reproductive behavior GO:0044705 387 0.015
generation of neurons GO:0048699 235 0.015
response to wounding GO:0009611 4 0.015
regulation of organelle organization GO:0033043 164 0.015
small molecule metabolic process GO:0044281 186 0.015
nucleic acid templated transcription GO:0097659 169 0.015
nucleobase containing small molecule metabolic process GO:0055086 115 0.015
posttranscriptional gene silencing by rna GO:0035194 143 0.015
nucleoside phosphate metabolic process GO:0006753 108 0.015
system process GO:0003008 136 0.015
protein modification by small protein conjugation or removal GO:0070647 40 0.015
cellular component assembly involved in morphogenesis GO:0010927 183 0.015
response to inorganic substance GO:0010035 50 0.014
cell projection morphogenesis GO:0048858 148 0.014
regulation of behavior GO:0050795 97 0.014
nucleotide metabolic process GO:0009117 108 0.014
regulation of nucleic acid templated transcription GO:1903506 165 0.014
cellular nitrogen compound catabolic process GO:0044270 119 0.014
Mouse
protein phosphorylation GO:0006468 85 0.014
purine nucleoside triphosphate metabolic process GO:0009144 87 0.014
nucleoside metabolic process GO:0009116 99 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.014
Mouse
autophagy GO:0006914 29 0.013
macromolecular complex assembly GO:0065003 193 0.013
Mouse
actomyosin structure organization GO:0031032 154 0.013
organic cyclic compound biosynthetic process GO:1901362 195 0.013
gastrulation GO:0007369 58 0.013
regulation of cell proliferation GO:0042127 105 0.013
purine nucleoside triphosphate catabolic process GO:0009146 72 0.013
tube morphogenesis GO:0035239 79 0.013
regulation of cellular biosynthetic process GO:0031326 189 0.013
embryonic morphogenesis GO:0048598 152 0.013
striated muscle myosin thick filament assembly GO:0071688 138 0.013
single organism transport GO:0044765 447 0.013
positive regulation of developmental process GO:0051094 408 0.013
defense response to bacterium GO:0042742 86 0.013
establishment of localization in cell GO:0051649 318 0.013
Zebrafish Mouse
chromosome organization GO:0051276 104 0.012
Zebrafish Mouse
posttranscriptional gene silencing GO:0016441 143 0.012
regulation of response to stimulus GO:0048583 243 0.012
neuron differentiation GO:0030182 217 0.012
epithelial cell proliferation GO:0050673 1 0.012
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
positive regulation of developmental growth GO:0048639 354 0.012
regulation of cellular protein metabolic process GO:0032268 75 0.012
ribonucleotide metabolic process GO:0009259 99 0.012
regulation of cellular catabolic process GO:0031329 51 0.012
phosphorus metabolic process GO:0006793 232 0.012
nervous system development GO:0007399 253 0.012
positive regulation of neurogenesis GO:0050769 4 0.012
oviposition GO:0018991 364 0.012
regulation of kinase activity GO:0043549 29 0.012
cell projection organization GO:0030030 231 0.012
single organism catabolic process GO:0044712 129 0.012
negative regulation of axonogenesis GO:0050771 2 0.012
regulation of cell communication GO:0010646 176 0.012
positive regulation of response to stimulus GO:0048584 55 0.012
regulation of rna metabolic process GO:0051252 173 0.011
heterocycle catabolic process GO:0046700 119 0.011
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.011
transcription from rna polymerase ii promoter GO:0006366 149 0.011
protein deubiquitination GO:0016579 2 0.011
gene silencing GO:0016458 143 0.011
myosin filament organization GO:0031033 138 0.011
glycosyl compound catabolic process GO:1901658 79 0.011
cellular response to dna damage stimulus GO:0006974 41 0.011
Human Mouse
cell morphogenesis GO:0000902 163 0.011
secretion by cell GO:0032940 138 0.011
single organism biosynthetic process GO:0044711 91 0.011
defense response to gram negative bacterium GO:0050829 64 0.011
negative regulation of cellular biosynthetic process GO:0031327 65 0.011
endocytosis GO:0006897 819 0.011
cell substrate adhesion GO:0031589 1 0.011
protein oligomerization GO:0051259 4 0.010
myofibril assembly GO:0030239 154 0.010
negative regulation of cell cycle GO:0045786 53 0.010
single organism localization GO:1902578 518 0.010
Zebrafish Mouse
regulation of gene expression GO:0010468 366 0.010
cellular macromolecular complex assembly GO:0034622 184 0.010
Mouse

mlh-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org