Caenorhabditis elegans

112 known processes

spd-1 (CELE_Y34D9A.4)

Protein SPD-1

spd-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle organization GO:0006996 783 0.418
single organism organelle organization GO:1902589 501 0.336
genitalia development GO:0048806 741 0.279
cellular protein modification process GO:0006464 207 0.277
mitotic spindle organization GO:0007052 81 0.248
muscle structure development GO:0061061 191 0.224
embryo development ending in birth or egg hatching GO:0009792 2992 0.220
regulation of primary metabolic process GO:0080090 292 0.219
reproductive system development GO:0061458 850 0.181
sex differentiation GO:0007548 909 0.172
anatomical structure formation involved in morphogenesis GO:0048646 250 0.167
Fly
regulation of cell cycle process GO:0010564 145 0.157
embryo development GO:0009790 3052 0.154
reproductive structure development GO:0048608 850 0.149
hermaphrodite genitalia development GO:0040035 734 0.144
meiotic nuclear division GO:0007126 300 0.141
establishment of localization GO:0051234 1171 0.139
macromolecular complex subunit organization GO:0043933 320 0.136
gonad development GO:0008406 840 0.132
signal transduction GO:0007165 317 0.131
regulation of biological quality GO:0065008 741 0.129
macromolecule modification GO:0043412 218 0.125
cytoskeleton organization GO:0007010 339 0.124
biosynthetic process GO:0009058 323 0.121
protein modification process GO:0036211 207 0.115
organelle fission GO:0048285 363 0.114
regulation of metabolic process GO:0019222 478 0.109
organic substance biosynthetic process GO:1901576 323 0.108
meiotic cell cycle process GO:1903046 170 0.107
negative regulation of biological process GO:0048519 567 0.106
gamete generation GO:0007276 461 0.104
Fly
cell cycle GO:0007049 526 0.102
chromosome organization GO:0051276 104 0.100
single organism reproductive process GO:0044702 1196 0.097
regulation of developmental process GO:0050793 684 0.094
macromolecule localization GO:0033036 771 0.094
Fly
cell motility GO:0048870 313 0.091
cell cycle process GO:0022402 482 0.091
multicellular organismal aging GO:0010259 812 0.090
meiotic cell cycle GO:0051321 335 0.089
regulation of nitrogen compound metabolic process GO:0051171 222 0.088
body morphogenesis GO:0010171 620 0.087
localization of cell GO:0051674 313 0.087
nervous system development GO:0007399 253 0.086
Fly
death GO:0016265 547 0.085
post embryonic development GO:0009791 2152 0.085
gene expression GO:0010467 412 0.084
regulation of cellular metabolic process GO:0031323 305 0.083
multicellular organism reproduction GO:0032504 819 0.083
protein metabolic process GO:0019538 422 0.082
regulation of gene expression GO:0010468 366 0.081
cellular protein metabolic process GO:0044267 279 0.079
mitotic chromosome movement towards spindle pole GO:0007079 2 0.078
phosphorus metabolic process GO:0006793 232 0.076
developmental process involved in reproduction GO:0003006 1165 0.075
oviposition GO:0018991 364 0.075
chromatin modification GO:0016568 32 0.074
regulation of macromolecule metabolic process GO:0060255 421 0.074
regulation of cell cycle GO:0051726 194 0.073
meiotic chromosome segregation GO:0045132 139 0.072
protein complex biogenesis GO:0070271 186 0.071
transport GO:0006810 1093 0.069
mitotic metaphase plate congression GO:0007080 5 0.069
multicellular organismal reproductive process GO:0048609 815 0.067
histone modification GO:0016570 30 0.066
protein complex assembly GO:0006461 186 0.066
aging GO:0007568 812 0.065
nucleic acid templated transcription GO:0097659 169 0.065
determination of adult lifespan GO:0008340 812 0.065
microtubule cytoskeleton organization involved in mitosis GO:1902850 12 0.064
organic substance catabolic process GO:1901575 294 0.063
programmed cell death GO:0012501 500 0.063
cellular macromolecule biosynthetic process GO:0034645 247 0.063
chromosome localization GO:0050000 10 0.063
endocytosis GO:0006897 819 0.062
protein catabolic process GO:0030163 162 0.062
cell death GO:0008219 547 0.060
maintenance of location GO:0051235 580 0.059
cell development GO:0048468 696 0.058
Fly
small molecule metabolic process GO:0044281 186 0.058
organelle assembly GO:0070925 214 0.058
regulation of cellular component organization GO:0051128 248 0.058
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.057
macromolecule catabolic process GO:0009057 202 0.057
cellular response to dna damage stimulus GO:0006974 41 0.056
regulation of rna biosynthetic process GO:2001141 165 0.056
mitotic sister chromatid segregation GO:0000070 38 0.055
lipid storage GO:0019915 565 0.054
vesicle mediated transport GO:0016192 852 0.054
protein complex subunit organization GO:0071822 280 0.054
receptor mediated endocytosis GO:0006898 715 0.053
mitotic cell cycle process GO:1903047 194 0.052
phagocytosis GO:0006909 115 0.052
metaphase plate congression GO:0051310 5 0.052
cellular response to stress GO:0033554 162 0.051
lipid localization GO:0010876 573 0.051
positive regulation of macromolecule metabolic process GO:0010604 149 0.051
dna conformation change GO:0071103 11 0.050
multi organism reproductive process GO:0044703 867 0.049
chromatin organization GO:0006325 32 0.048
regulation of multicellular organismal process GO:0051239 726 0.048
striated muscle cell development GO:0055002 157 0.048
spindle organization GO:0007051 92 0.048
multi organism reproductive behavior GO:0044705 387 0.048
establishment of chromosome localization GO:0051303 10 0.046
chromosome segregation GO:0007059 180 0.046
response to external stimulus GO:0009605 289 0.046
polar body extrusion after meiotic divisions GO:0040038 14 0.045
positive regulation of mitotic sister chromatid separation GO:1901970 1 0.045
cell migration GO:0016477 306 0.045
neurogenesis GO:0022008 236 0.045
Fly
development of primary sexual characteristics GO:0045137 840 0.044
transcription from rna polymerase ii promoter GO:0006366 149 0.044
regulation of cellular ketone metabolic process GO:0010565 3 0.044
microtubule polymerization or depolymerization GO:0031109 22 0.043
regulation of growth GO:0040008 409 0.043
regulation of cellular biosynthetic process GO:0031326 189 0.043
macromolecular complex assembly GO:0065003 193 0.042
proteolysis GO:0006508 61 0.041
organic cyclic compound biosynthetic process GO:1901362 195 0.041
organ development GO:0048513 1102 0.040
carbohydrate derivative catabolic process GO:1901136 82 0.040
regulation of organelle organization GO:0033043 164 0.040
regulation of biosynthetic process GO:0009889 189 0.040
molting cycle GO:0042303 281 0.040
cellular component assembly involved in morphogenesis GO:0010927 183 0.039
spindle assembly involved in mitosis GO:0090307 6 0.039
covalent chromatin modification GO:0016569 30 0.039
negative regulation of macromolecule metabolic process GO:0010605 229 0.039
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.039
Fly
multi organism behavior GO:0051705 389 0.038
carboxylic acid metabolic process GO:0019752 34 0.038
locomotion GO:0040011 1634 0.038
actomyosin structure organization GO:0031032 154 0.038
cellular biosynthetic process GO:0044249 315 0.036
regulation of vulval development GO:0040028 248 0.036
regulation of chromosome organization GO:0033044 20 0.036
signaling GO:0023052 401 0.035
single organism localization GO:1902578 518 0.035
Fly
multi multicellular organism process GO:0044706 390 0.035
sister chromatid segregation GO:0000819 46 0.035
regulation of developmental growth GO:0048638 389 0.034
development of primary male sexual characteristics GO:0046546 4 0.034
regulation of nucleic acid templated transcription GO:1903506 165 0.034
germ cell development GO:0007281 351 0.033
Fly
cellular nitrogen compound biosynthetic process GO:0044271 192 0.033
oxoacid metabolic process GO:0043436 47 0.033
establishment of spindle orientation GO:0051294 34 0.032
apoptotic process GO:0006915 478 0.032
cellular macromolecular complex assembly GO:0034622 184 0.032
positive regulation of phosphorus metabolic process GO:0010562 56 0.031
cellular protein complex assembly GO:0043623 178 0.031
aromatic compound catabolic process GO:0019439 116 0.030
cellular component assembly GO:0022607 293 0.030
cellular component biogenesis GO:0044085 297 0.029
phosphate containing compound metabolic process GO:0006796 232 0.029
positive regulation of growth GO:0045927 369 0.029
positive regulation of chromosome organization GO:2001252 2 0.029
myofibril assembly GO:0030239 154 0.029
cell division GO:0051301 262 0.028
generation of neurons GO:0048699 235 0.028
glycosyl compound catabolic process GO:1901658 79 0.028
cellular amine metabolic process GO:0044106 15 0.028
regulation of multi organism process GO:0043900 69 0.027
peptidyl amino acid modification GO:0018193 58 0.027
nucleus organization GO:0006997 38 0.027
regulation of cell division GO:0051302 142 0.027
negative regulation of vulval development GO:0040027 206 0.027
ubiquitin dependent protein catabolic process GO:0006511 32 0.026
positive regulation of cellular process GO:0048522 332 0.026
Fly
transcription dna templated GO:0006351 168 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
positive regulation of cellular metabolic process GO:0031325 178 0.026
microtubule based process GO:0007017 182 0.026
cellular catabolic process GO:0044248 199 0.026
regulation of programmed cell death GO:0043067 50 0.026
microtubule anchoring GO:0034453 8 0.025
regulation of nematode larval development GO:0061062 260 0.025
regulation of meiosis GO:0040020 94 0.025
catabolic process GO:0009056 318 0.025
tube development GO:0035295 126 0.024
regulation of cellular catabolic process GO:0031329 51 0.024
nucleobase containing compound biosynthetic process GO:0034654 184 0.024
establishment of organelle localization GO:0051656 123 0.023
muscle cell development GO:0055001 158 0.023
regulation of nuclear division GO:0051783 115 0.023
negative regulation of gene expression GO:0010629 217 0.023
positive regulation of gene expression GO:0010628 112 0.023
dna metabolic process GO:0006259 74 0.022
female meiotic division GO:0007143 17 0.022
developmental growth GO:0048589 412 0.022
protein oligomerization GO:0051259 4 0.022
striated muscle cell differentiation GO:0051146 158 0.022
male sex differentiation GO:0046661 86 0.022
regulation of cell death GO:0010941 65 0.021
single organism transport GO:0044765 447 0.021
Fly
regulation of multicellular organismal development GO:2000026 317 0.021
cellular component movement GO:0006928 388 0.021
cytokinesis GO:0000910 80 0.021
modification dependent protein catabolic process GO:0019941 32 0.021
tissue development GO:0009888 112 0.020
Fly
regulation of multicellular organism growth GO:0040014 373 0.020
single organism signaling GO:0044700 401 0.020
multicellular organismal reproductive behavior GO:0033057 384 0.020
negative regulation of nematode larval development GO:0061064 208 0.020
sexual reproduction GO:0019953 546 0.020
Fly
regulation of transcription dna templated GO:0006355 164 0.020
embryonic morphogenesis GO:0048598 152 0.020
heterocycle biosynthetic process GO:0018130 187 0.020
negative regulation of developmental process GO:0051093 227 0.020
striated muscle myosin thick filament assembly GO:0071688 138 0.020
regulation of cell cycle phase transition GO:1901987 13 0.020
attachment of spindle microtubules to kinetochore GO:0008608 8 0.020
myosin filament organization GO:0031033 138 0.019
actin cytoskeleton organization GO:0030036 184 0.019
female gamete generation GO:0007292 254 0.019
Fly
positive regulation of rna metabolic process GO:0051254 103 0.019
head development GO:0060322 1 0.019
mitotic nuclear division GO:0007067 89 0.019
macromolecule biosynthetic process GO:0009059 250 0.019
amine metabolic process GO:0009308 15 0.018
muscle cell differentiation GO:0042692 171 0.018
negative regulation of cellular process GO:0048523 239 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.018
multicellular organism growth GO:0035264 385 0.018
oogenesis GO:0048477 229 0.018
Fly
cell projection organization GO:0030030 231 0.018
collagen and cuticulin based cuticle development GO:0040002 99 0.018
negative regulation of nucleic acid templated transcription GO:1903507 53 0.017
internal peptidyl lysine acetylation GO:0018393 3 0.017
positive regulation of protein metabolic process GO:0051247 45 0.017
ribonucleotide catabolic process GO:0009261 75 0.017
organonitrogen compound metabolic process GO:1901564 151 0.017
positive regulation of multicellular organism growth GO:0040018 352 0.017
growth GO:0040007 562 0.017
inductive cell migration GO:0040039 145 0.017
membrane organization GO:0061024 135 0.016
negative regulation of multicellular organismal process GO:0051241 236 0.016
regulation of protein metabolic process GO:0051246 81 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.016
cell cycle dna replication GO:0044786 3 0.016
cellular ketone metabolic process GO:0042180 14 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of gene expression epigenetic GO:0040029 163 0.016
regulation of cellular protein metabolic process GO:0032268 75 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.015
cell cycle phase transition GO:0044770 19 0.015
engulfment of apoptotic cell GO:0043652 94 0.015
posttranscriptional regulation of gene expression GO:0010608 166 0.015
mitotic sister chromatid separation GO:0051306 13 0.015
response to abiotic stimulus GO:0009628 152 0.015
organic substance transport GO:0071702 113 0.015
Fly
membrane invagination GO:0010324 98 0.015
cellular amino acid metabolic process GO:0006520 15 0.015
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.015
neuron development GO:0048666 199 0.015
positive regulation of metabolic process GO:0009893 187 0.014
negative regulation of programmed cell death GO:0043069 19 0.014
organic acid metabolic process GO:0006082 47 0.014
regulation of rna metabolic process GO:0051252 173 0.014
vulval development GO:0040025 333 0.014
myosin filament assembly GO:0031034 138 0.014
posttranscriptional gene silencing GO:0016441 143 0.014
negative regulation of metabolic process GO:0009892 240 0.014
rna metabolic process GO:0016070 228 0.014
regulation of reproductive process GO:2000241 66 0.014
rna interference GO:0016246 137 0.014
kinetochore assembly GO:0051382 5 0.014
muscle tissue development GO:0060537 1 0.014
cellular localization GO:0051641 360 0.014
Fly
actin filament based process GO:0030029 191 0.013
gene silencing by rna GO:0031047 143 0.013
single fertilization GO:0007338 61 0.013
chromatin assembly GO:0031497 1 0.013
regulation of apoptotic signaling pathway GO:2001233 1 0.013
cellular component morphogenesis GO:0032989 318 0.013
organophosphate catabolic process GO:0046434 81 0.013
positive regulation of chromosome segregation GO:0051984 1 0.013
homeostatic process GO:0042592 51 0.013
nucleobase containing compound metabolic process GO:0006139 406 0.013
neuron differentiation GO:0030182 217 0.013
positive regulation of developmental process GO:0051094 408 0.013
posttranscriptional gene silencing by rna GO:0035194 143 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.013
positive regulation of locomotion GO:0040017 42 0.013
positive regulation of developmental growth GO:0048639 354 0.013
purine containing compound catabolic process GO:0072523 75 0.013
pattern specification process GO:0007389 59 0.012
rna biosynthetic process GO:0032774 169 0.012
male anatomical structure morphogenesis GO:0090598 78 0.012
nucleotide metabolic process GO:0009117 108 0.012
heterocycle catabolic process GO:0046700 119 0.012
positive regulation of nucleic acid templated transcription GO:1903508 102 0.012
establishment of spindle localization GO:0051293 51 0.012
pole plasm assembly GO:0007315 2 0.012
regulation of response to stimulus GO:0048583 243 0.012
regulation of phosphorus metabolic process GO:0051174 81 0.012
response to biotic stimulus GO:0009607 101 0.012
regulation of meiotic cell cycle GO:0051445 136 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.012
protein modification by small protein conjugation or removal GO:0070647 40 0.012
cuticle development GO:0042335 100 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
regulation of macromolecule biosynthetic process GO:0010556 189 0.012
positive regulation of protein modification process GO:0031401 29 0.012
protein phosphorylation GO:0006468 85 0.012
single organism biosynthetic process GO:0044711 91 0.012
meiotic cytokinesis GO:0033206 15 0.011
regulation of post embryonic development GO:0048580 260 0.011
peptidyl lysine acetylation GO:0018394 3 0.011
behavior GO:0007610 527 0.011
positive regulation of multicellular organismal process GO:0051240 417 0.011
reproductive behavior GO:0019098 387 0.011
phagocytosis engulfment GO:0006911 98 0.011
internal protein amino acid acetylation GO:0006475 3 0.011
phosphorylation GO:0016310 116 0.011
oocyte development GO:0048599 44 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 1 0.011
single organism catabolic process GO:0044712 129 0.011
chromatin remodeling GO:0006338 2 0.011
maintenance of protein location GO:0045185 15 0.011
spindle checkpoint GO:0031577 4 0.011
regulation of protein modification process GO:0031399 46 0.010
metaphase anaphase transition of cell cycle GO:0044784 15 0.010
regulation of ion transport GO:0043269 39 0.010
glycosyl compound metabolic process GO:1901657 100 0.010
negative regulation of post embryonic development GO:0048581 208 0.010

spd-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.037
anemia DOID:2355 0 0.037
bone marrow disease DOID:4961 0 0.037
hematopoietic system disease DOID:74 0 0.037
aplastic anemia DOID:12449 0 0.037
disease of anatomical entity DOID:7 0 0.037