Caenorhabditis elegans

29 known processes

shk-1 (CELE_ZK1321.2)

Protein SHK-1

shk-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 1171 0.359
post embryonic development GO:0009791 2152 0.210
transport GO:0006810 1093 0.199
signaling GO:0023052 401 0.185
embryo development GO:0009790 3052 0.174
ion transport GO:0006811 113 0.170
regulation of signaling GO:0023051 172 0.161
organ development GO:0048513 1102 0.142
single organism transport GO:0044765 447 0.133
macromolecule localization GO:0033036 771 0.117
single organism signaling GO:0044700 401 0.113
negative regulation of biological process GO:0048519 567 0.112
regulation of biological quality GO:0065008 741 0.108
generation of neurons GO:0048699 235 0.108
locomotion GO:0040011 1634 0.101
regulation of response to stimulus GO:0048583 243 0.101
cell development GO:0048468 696 0.100
protein metabolic process GO:0019538 422 0.096
signal transduction GO:0007165 317 0.096
multicellular organismal aging GO:0010259 812 0.093
single organism localization GO:1902578 518 0.093
lipid localization GO:0010876 573 0.087
vesicle mediated transport GO:0016192 852 0.085
response to chemical GO:0042221 356 0.083
nervous system development GO:0007399 253 0.083
neuron development GO:0048666 199 0.079
lipid storage GO:0019915 565 0.078
reproductive system development GO:0061458 850 0.078
multi organism reproductive process GO:0044703 867 0.072
protein modification process GO:0036211 207 0.071
post embryonic organ development GO:0048569 336 0.070
cellular response to organic substance GO:0071310 119 0.070
maintenance of location GO:0051235 580 0.070
regulation of signal transduction GO:0009966 135 0.069
developmental process involved in reproduction GO:0003006 1165 0.068
neurogenesis GO:0022008 236 0.067
phosphorus metabolic process GO:0006793 232 0.067
organelle organization GO:0006996 783 0.066
negative regulation of cellular process GO:0048523 239 0.065
embryo development ending in birth or egg hatching GO:0009792 2992 0.065
regulation of cellular metabolic process GO:0031323 305 0.064
endocytosis GO:0006897 819 0.063
development of primary sexual characteristics GO:0045137 840 0.062
neuron differentiation GO:0030182 217 0.062
sex differentiation GO:0007548 909 0.061
multicellular organism reproduction GO:0032504 819 0.059
regulation of locomotion GO:0040012 161 0.059
aging GO:0007568 812 0.057
macromolecule modification GO:0043412 218 0.057
catabolic process GO:0009056 318 0.056
cell surface receptor signaling pathway GO:0007166 149 0.056
single organism organelle organization GO:1902589 501 0.054
response to external stimulus GO:0009605 289 0.050
regulation of cell communication GO:0010646 176 0.050
regulation of metabolic process GO:0019222 478 0.049
regulation of macromolecule metabolic process GO:0060255 421 0.049
protein catabolic process GO:0030163 162 0.048
negative regulation of response to stimulus GO:0048585 73 0.047
macromolecule catabolic process GO:0009057 202 0.046
determination of adult lifespan GO:0008340 812 0.045
positive regulation of cellular process GO:0048522 332 0.045
cellular component morphogenesis GO:0032989 318 0.044
regulation of multicellular organismal process GO:0051239 726 0.044
organic substance catabolic process GO:1901575 294 0.043
localization of cell GO:0051674 313 0.043
cellular protein metabolic process GO:0044267 279 0.042
reproductive structure development GO:0048608 850 0.041
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.041
metal ion transport GO:0030001 49 0.040
multicellular organismal reproductive process GO:0048609 815 0.040
receptor mediated endocytosis GO:0006898 715 0.040
cellular component assembly GO:0022607 293 0.039
negative regulation of multicellular organismal process GO:0051241 236 0.038
multi organism behavior GO:0051705 389 0.037
vulval development GO:0040025 333 0.036
response to organic substance GO:0010033 131 0.036
cell projection organization GO:0030030 231 0.036
behavior GO:0007610 527 0.036
cytoskeleton organization GO:0007010 339 0.034
multi multicellular organism process GO:0044706 390 0.034
hermaphrodite genitalia development GO:0040035 734 0.034
regulation of phosphate metabolic process GO:0019220 81 0.033
cellular localization GO:0051641 360 0.032
cell proliferation GO:0008283 116 0.032
positive regulation of developmental process GO:0051094 408 0.032
response to mechanical stimulus GO:0009612 28 0.031
body morphogenesis GO:0010171 620 0.031
cellular protein modification process GO:0006464 207 0.030
regulation of localization GO:0032879 194 0.029
cell division GO:0051301 262 0.029
regulation of protein metabolic process GO:0051246 81 0.028
immune response GO:0006955 192 0.028
phosphate containing compound metabolic process GO:0006796 232 0.028
single organism reproductive process GO:0044702 1196 0.028
negative regulation of metabolic process GO:0009892 240 0.028
growth GO:0040007 562 0.028
response to wounding GO:0009611 4 0.027
regulation of transport GO:0051049 91 0.027
actomyosin structure organization GO:0031032 154 0.027
negative regulation of signal transduction GO:0009968 60 0.026
negative regulation of macromolecule metabolic process GO:0010605 229 0.026
secretion by cell GO:0032940 138 0.026
cellular component biogenesis GO:0044085 297 0.026
monovalent inorganic cation transport GO:0015672 33 0.026
regulation of phosphorus metabolic process GO:0051174 81 0.026
phosphorylation GO:0016310 116 0.026
organelle assembly GO:0070925 214 0.026
negative regulation of developmental process GO:0051093 227 0.026
positive regulation of synaptic transmission dopaminergic GO:0032226 1 0.025
cellular component movement GO:0006928 388 0.025
reproductive behavior GO:0019098 387 0.025
regulation of nematode larval development GO:0061062 260 0.025
purine ribonucleotide metabolic process GO:0009150 95 0.024
embryonic morphogenesis GO:0048598 152 0.024
oviposition GO:0018991 364 0.024
protein phosphorylation GO:0006468 85 0.024
muscle cell differentiation GO:0042692 171 0.024
gonad development GO:0008406 840 0.023
cellular protein complex assembly GO:0043623 178 0.023
positive regulation of multicellular organism growth GO:0040018 352 0.023
multicellular organismal reproductive behavior GO:0033057 384 0.023
cation transport GO:0006812 78 0.023
multi organism reproductive behavior GO:0044705 387 0.023
purine nucleotide metabolic process GO:0006163 95 0.023
biosynthetic process GO:0009058 323 0.023
regulation of multicellular organism growth GO:0040014 373 0.022
regulation of developmental process GO:0050793 684 0.022
establishment of localization in cell GO:0051649 318 0.022
positive regulation of metabolic process GO:0009893 187 0.022
head development GO:0060322 1 0.022
phagocytosis GO:0006909 115 0.022
purine ribonucleotide catabolic process GO:0009154 75 0.022
positive regulation of developmental growth GO:0048639 354 0.022
chemotaxis GO:0006935 120 0.022
organ morphogenesis GO:0009887 67 0.022
macromolecular complex subunit organization GO:0043933 320 0.022
regulation of gene expression GO:0010468 366 0.022
anatomical structure formation involved in morphogenesis GO:0048646 250 0.022
actin cytoskeleton organization GO:0030036 184 0.021
positive regulation of neurogenesis GO:0050769 4 0.021
organophosphate metabolic process GO:0019637 125 0.021
nucleobase containing compound metabolic process GO:0006139 406 0.021
regulation of nitrogen compound metabolic process GO:0051171 222 0.021
organic substance transport GO:0071702 113 0.021
multicellular organism growth GO:0035264 385 0.020
engulfment of apoptotic cell GO:0043652 94 0.020
cell migration GO:0016477 306 0.020
cellular biosynthetic process GO:0044249 315 0.020
response to endogenous stimulus GO:0009719 33 0.020
negative regulation of cell communication GO:0010648 61 0.020
positive regulation of multicellular organismal process GO:0051240 417 0.019
protein localization GO:0008104 205 0.019
programmed cell death GO:0012501 500 0.019
striated muscle cell development GO:0055002 157 0.019
organonitrogen compound metabolic process GO:1901564 151 0.019
defense response GO:0006952 296 0.019
myofibril assembly GO:0030239 154 0.019
negative regulation of gene expression GO:0010629 217 0.019
response to other organism GO:0051707 101 0.019
regulation of mitotic cell cycle GO:0007346 76 0.019
positive regulation of signaling GO:0023056 66 0.019
positive regulation of growth GO:0045927 369 0.019
membrane organization GO:0061024 135 0.019
striated muscle cell differentiation GO:0051146 158 0.018
cellular response to chemical stimulus GO:0070887 129 0.018
positive regulation of phosphate metabolic process GO:0045937 56 0.018
pattern specification process GO:0007389 59 0.018
lipid metabolic process GO:0006629 77 0.018
developmental growth GO:0048589 412 0.018
regulation of cellular protein metabolic process GO:0032268 75 0.018
secretion GO:0046903 147 0.018
heterocycle catabolic process GO:0046700 119 0.018
developmental induction GO:0031128 1 0.018
acetylcholine transport GO:0015870 16 0.018
positive regulation of phosphorus metabolic process GO:0010562 56 0.017
regulation of primary metabolic process GO:0080090 292 0.017
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.017
cell motility GO:0048870 313 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.017
muscle structure development GO:0061061 191 0.017
regulation of organ morphogenesis GO:2000027 4 0.017
phagocytosis engulfment GO:0006911 98 0.017
mitotic cell cycle process GO:1903047 194 0.017
regulation of hydrolase activity GO:0051336 45 0.017
anion transport GO:0006820 30 0.017
macromolecular complex assembly GO:0065003 193 0.016
organonitrogen compound catabolic process GO:1901565 90 0.016
epithelial tube morphogenesis GO:0060562 1 0.016
regulation of growth GO:0040008 409 0.016
cell cycle process GO:0022402 482 0.016
cellular catabolic process GO:0044248 199 0.016
genitalia development GO:0048806 741 0.016
cellular component assembly involved in morphogenesis GO:0010927 183 0.016
negative regulation of signaling GO:0023057 61 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.015
regulation of cellular component movement GO:0051270 62 0.015
sexual reproduction GO:0019953 546 0.015
molting cycle GO:0042303 281 0.015
sensory organ morphogenesis GO:0090596 2 0.015
regulation of cellular biosynthetic process GO:0031326 189 0.015
apoptotic cell clearance GO:0043277 111 0.015
protein complex biogenesis GO:0070271 186 0.015
cellular response to abiotic stimulus GO:0071214 4 0.015
death GO:0016265 547 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.015
membrane invagination GO:0010324 98 0.015
myosin filament organization GO:0031033 138 0.015
enzyme linked receptor protein signaling pathway GO:0007167 50 0.014
actin filament based process GO:0030029 191 0.014
rna metabolic process GO:0016070 228 0.014
muscle cell development GO:0055001 158 0.014
regulation of catabolic process GO:0009894 57 0.014
ribonucleoside triphosphate catabolic process GO:0009203 72 0.014
organic substance biosynthetic process GO:1901576 323 0.014
apoptotic process GO:0006915 478 0.014
cell death GO:0008219 547 0.014
cellular lipid metabolic process GO:0044255 40 0.014
regulation of molecular function GO:0065009 89 0.014
epithelial cell proliferation GO:0050673 1 0.014
regulation of biosynthetic process GO:0009889 189 0.014
oogenesis GO:0048477 229 0.014
feeding behavior GO:0007631 70 0.014
system process GO:0003008 136 0.014
sensory perception of taste GO:0050909 4 0.014
nucleoside triphosphate catabolic process GO:0009143 72 0.014
cellular macromolecular complex assembly GO:0034622 184 0.014
regulation of phosphorylation GO:0042325 45 0.014
negative regulation of biosynthetic process GO:0009890 65 0.014
gamete generation GO:0007276 461 0.013
positive regulation of neuron differentiation GO:0045666 4 0.013
mapk cascade GO:0000165 31 0.013
small molecule metabolic process GO:0044281 186 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of cell cycle GO:0051726 194 0.013
positive regulation of hydrolase activity GO:0051345 38 0.013
cell morphogenesis GO:0000902 163 0.013
regulation of gastrulation GO:0010470 4 0.013
neuron projection development GO:0031175 187 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.012
positive regulation of catalytic activity GO:0043085 59 0.012
myosin filament assembly GO:0031034 138 0.012
regulation of cell proliferation GO:0042127 105 0.012
nucleic acid templated transcription GO:0097659 169 0.012
response to abiotic stimulus GO:0009628 152 0.012
negative regulation of post embryonic development GO:0048581 208 0.012
purine nucleoside metabolic process GO:0042278 92 0.012
mitotic spindle organization GO:0007052 81 0.012
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 2 0.012
positive regulation of cellular metabolic process GO:0031325 178 0.012
nucleobase containing compound catabolic process GO:0034655 114 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.012
gene expression GO:0010467 412 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.011
nucleoside phosphate catabolic process GO:1901292 77 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 34 0.011
regulation of cell division GO:0051302 142 0.011
muscle system process GO:0003012 43 0.011
nucleoside triphosphate metabolic process GO:0009141 87 0.011
response to biotic stimulus GO:0009607 101 0.011
germ cell development GO:0007281 351 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
regulation of developmental growth GO:0048638 389 0.011
negative regulation of vulval development GO:0040027 206 0.011
guanosine containing compound catabolic process GO:1901069 48 0.011
positive regulation of locomotion GO:0040017 42 0.011
negative regulation of cellular metabolic process GO:0031324 95 0.011
regulation of cellular component organization GO:0051128 248 0.011
regulation of organelle organization GO:0033043 164 0.011
amine metabolic process GO:0009308 15 0.011
positive regulation of molecular function GO:0044093 61 0.011
striated muscle myosin thick filament assembly GO:0071688 138 0.011
carboxylic acid metabolic process GO:0019752 34 0.011
tube development GO:0035295 126 0.011
protein complex subunit organization GO:0071822 280 0.011
regulation of vulval development GO:0040028 248 0.011
protein complex assembly GO:0006461 186 0.010
organic acid metabolic process GO:0006082 47 0.010
ribonucleoside triphosphate metabolic process GO:0009199 87 0.010
guanosine containing compound metabolic process GO:1901068 49 0.010
regulation of lipid metabolic process GO:0019216 4 0.010
nucleic acid metabolic process GO:0090304 299 0.010
glycosyl compound catabolic process GO:1901658 79 0.010
transmembrane transport GO:0055085 110 0.010
regulation of apoptotic signaling pathway GO:2001233 1 0.010
aromatic compound catabolic process GO:0019439 116 0.010
regulation of catalytic activity GO:0050790 78 0.010
cellular nitrogen compound biosynthetic process GO:0044271 192 0.010
purine nucleoside triphosphate metabolic process GO:0009144 87 0.010
response to bacterium GO:0009617 86 0.010

shk-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011