Caenorhabditis elegans

51 known processes

rpn-12 (CELE_ZK20.5)

Protein RPN-12

rpn-12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 32 0.905
Yeast
catabolic process GO:0009056 318 0.875
Yeast
ubiquitin dependent protein catabolic process GO:0006511 32 0.847
Yeast
cellular catabolic process GO:0044248 199 0.833
Yeast
post embryonic development GO:0009791 2152 0.772
pronuclear migration GO:0035046 51 0.724
protein catabolic process GO:0030163 162 0.674
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 32 0.666
Yeast
cellular protein catabolic process GO:0044257 37 0.645
Yeast
embryo development GO:0009790 3052 0.616
macromolecule catabolic process GO:0009057 202 0.609
Yeast
modification dependent macromolecule catabolic process GO:0043632 32 0.566
Yeast
establishment of localization GO:0051234 1171 0.557
cellular protein metabolic process GO:0044267 279 0.544
Yeast
embryo development ending in birth or egg hatching GO:0009792 2992 0.530
hermaphrodite genitalia development GO:0040035 734 0.491
negative regulation of vulval development GO:0040027 206 0.489
proteolysis GO:0006508 61 0.477
Yeast Fly
protein metabolic process GO:0019538 422 0.447
Yeast Fly
cellular response to dna damage stimulus GO:0006974 41 0.440
single organism reproductive process GO:0044702 1196 0.433
proteasomal protein catabolic process GO:0010498 20 0.414
organic substance catabolic process GO:1901575 294 0.411
Yeast
sexual reproduction GO:0019953 546 0.408
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 20 0.372
multicellular organismal aging GO:0010259 812 0.358
multicellular organismal reproductive process GO:0048609 815 0.337
transport GO:0006810 1093 0.329
gonad development GO:0008406 840 0.309
organ development GO:0048513 1102 0.307
regulation of multicellular organismal process GO:0051239 726 0.307
response to external stimulus GO:0009605 289 0.297
genitalia development GO:0048806 741 0.289
reproductive structure development GO:0048608 850 0.283
regulation of developmental process GO:0050793 684 0.281
organelle organization GO:0006996 783 0.264
Fly
determination of adult lifespan GO:0008340 812 0.249
regulation of transcription dna templated GO:0006355 164 0.245
development of primary sexual characteristics GO:0045137 840 0.239
aging GO:0007568 812 0.239
developmental process involved in reproduction GO:0003006 1165 0.236
locomotion GO:0040011 1634 0.220
cellular macromolecule catabolic process GO:0044265 73 0.212
Yeast
endocytosis GO:0006897 819 0.210
reproductive system development GO:0061458 850 0.209
single fertilization GO:0007338 61 0.189
cytoskeleton organization GO:0007010 339 0.183
Fly
protein complex assembly GO:0006461 186 0.181
cellular component assembly GO:0022607 293 0.180
macromolecule localization GO:0033036 771 0.175
macromolecular complex assembly GO:0065003 193 0.173
cell cycle process GO:0022402 482 0.169
Fly
sex differentiation GO:0007548 909 0.162
vesicle mediated transport GO:0016192 852 0.161
macromolecular complex subunit organization GO:0043933 320 0.160
Fly
cellular localization GO:0051641 360 0.157
single organism localization GO:1902578 518 0.154
negative regulation of biological process GO:0048519 567 0.153
cellular response to stress GO:0033554 162 0.144
regulation of metabolic process GO:0019222 478 0.139
regulation of vulval development GO:0040028 248 0.134
cellular protein complex assembly GO:0043623 178 0.133
regulation of biological quality GO:0065008 741 0.129
cell death GO:0008219 547 0.128
cellular macromolecule biosynthetic process GO:0034645 247 0.127
single organism transport GO:0044765 447 0.127
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.126
regulation of cellular metabolic process GO:0031323 305 0.124
heterocycle biosynthetic process GO:0018130 187 0.123
receptor mediated endocytosis GO:0006898 715 0.120
body morphogenesis GO:0010171 620 0.120
fertilization GO:0009566 63 0.119
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.115
regulation of macromolecule biosynthetic process GO:0010556 189 0.108
nucleobase containing compound metabolic process GO:0006139 406 0.108
multi organism reproductive process GO:0044703 867 0.107
negative regulation of cellular process GO:0048523 239 0.105
regulation of rna biosynthetic process GO:2001141 165 0.105
establishment of localization in cell GO:0051649 318 0.105
apoptotic process GO:0006915 478 0.104
cell development GO:0048468 696 0.103
cellular protein modification process GO:0006464 207 0.101
phosphate containing compound metabolic process GO:0006796 232 0.101
transcription from rna polymerase ii promoter GO:0006366 149 0.098
negative regulation of nematode larval development GO:0061064 208 0.098
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.097
regulation of gene expression GO:0010468 366 0.096
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.095
regulation of macromolecule metabolic process GO:0060255 421 0.094
germ cell development GO:0007281 351 0.094
lipid localization GO:0010876 573 0.092
programmed cell death GO:0012501 500 0.089
organonitrogen compound metabolic process GO:1901564 151 0.086
meiotic chromosome segregation GO:0045132 139 0.083
multicellular organism growth GO:0035264 385 0.082
growth GO:0040007 562 0.082
female gamete generation GO:0007292 254 0.081
regulation of post embryonic development GO:0048580 260 0.081
regulation of nematode larval development GO:0061062 260 0.081
cellular nitrogen compound biosynthetic process GO:0044271 192 0.079
maintenance of location GO:0051235 580 0.078
negative regulation of developmental process GO:0051093 227 0.076
mitotic cell cycle process GO:1903047 194 0.074
Fly
negative regulation of post embryonic development GO:0048581 208 0.074
protein complex subunit organization GO:0071822 280 0.073
Fly
positive regulation of multicellular organism growth GO:0040018 352 0.070
lipid storage GO:0019915 565 0.070
gamete generation GO:0007276 461 0.068
chromosome organization GO:0051276 104 0.067
cellular macromolecular complex assembly GO:0034622 184 0.065
organic substance biosynthetic process GO:1901576 323 0.065
organic cyclic compound biosynthetic process GO:1901362 195 0.065
multicellular organism reproduction GO:0032504 819 0.065
purine ribonucleoside triphosphate metabolic process GO:0009205 87 0.064
rna biosynthetic process GO:0032774 169 0.063
meiotic cell cycle process GO:1903046 170 0.063
negative regulation of multicellular organismal process GO:0051241 236 0.063
molting cycle GO:0042303 281 0.062
er associated ubiquitin dependent protein catabolic process GO:0030433 6 0.062
cell motility GO:0048870 313 0.061
regulation of developmental growth GO:0048638 389 0.059
positive regulation of developmental growth GO:0048639 354 0.059
secretion by cell GO:0032940 138 0.056
cell cycle GO:0007049 526 0.055
Fly
cellular biosynthetic process GO:0044249 315 0.055
meiotic cell cycle GO:0051321 335 0.054
positive regulation of growth GO:0045927 369 0.054
gene expression GO:0010467 412 0.053
mitotic spindle organization GO:0007052 81 0.053
Fly
nucleobase containing compound biosynthetic process GO:0034654 184 0.053
protein complex biogenesis GO:0070271 186 0.053
developmental growth GO:0048589 412 0.052
regulation of nucleic acid templated transcription GO:1903506 165 0.052
regulation of primary metabolic process GO:0080090 292 0.052
aromatic compound biosynthetic process GO:0019438 192 0.050
spindle organization GO:0007051 92 0.050
Fly
nucleoside metabolic process GO:0009116 99 0.049
nervous system development GO:0007399 253 0.049
Fly
positive regulation of metabolic process GO:0009893 187 0.049
macromolecule modification GO:0043412 218 0.049
regulation of localization GO:0032879 194 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.048
organelle fission GO:0048285 363 0.048
cell migration GO:0016477 306 0.047
positive regulation of developmental process GO:0051094 408 0.047
response to chemical GO:0042221 356 0.046
transcription dna templated GO:0006351 168 0.045
glycosyl compound metabolic process GO:1901657 100 0.044
negative regulation of macromolecule metabolic process GO:0010605 229 0.044
oviposition GO:0018991 364 0.044
localization of cell GO:0051674 313 0.044
regulation of multicellular organism growth GO:0040014 373 0.044
protein localization GO:0008104 205 0.044
nucleic acid templated transcription GO:0097659 169 0.043
phosphorus metabolic process GO:0006793 232 0.043
pole plasm assembly GO:0007315 2 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.042
organelle assembly GO:0070925 214 0.042
single organism signaling GO:0044700 401 0.042
vulval development GO:0040025 333 0.041
negative regulation of metabolic process GO:0009892 240 0.041
regulation of biosynthetic process GO:0009889 189 0.039
death GO:0016265 547 0.039
positive regulation of rna biosynthetic process GO:1902680 102 0.039
cell proliferation GO:0008283 116 0.038
Fly
nucleic acid metabolic process GO:0090304 299 0.038
regulation of growth GO:0040008 409 0.037
transcription initiation from rna polymerase ii promoter GO:0006367 2 0.036
nucleotide metabolic process GO:0009117 108 0.036
chromosome segregation GO:0007059 180 0.036
neuron differentiation GO:0030182 217 0.036
regulation of cellular component organization GO:0051128 248 0.036
posttranscriptional gene silencing by rna GO:0035194 143 0.035
positive regulation of cellular process GO:0048522 332 0.035
regulation of cellular biosynthetic process GO:0031326 189 0.035
heterocycle catabolic process GO:0046700 119 0.035
cell division GO:0051301 262 0.035
nucleoside phosphate catabolic process GO:1901292 77 0.034
posttranscriptional regulation of gene expression GO:0010608 166 0.034
er associated misfolded protein catabolic process GO:0071712 4 0.034
regulation of cellular catabolic process GO:0031329 51 0.033
positive regulation of nucleic acid templated transcription GO:1903508 102 0.033
positive regulation of cellular metabolic process GO:0031325 178 0.033
cellular component biogenesis GO:0044085 297 0.033
single organism organelle organization GO:1902589 501 0.032
Fly
microtubule based process GO:0007017 182 0.032
Fly
positive regulation of molecular function GO:0044093 61 0.032
neurogenesis GO:0022008 236 0.032
Fly
aromatic compound catabolic process GO:0019439 116 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 72 0.032
regulation of rna metabolic process GO:0051252 173 0.032
secretion GO:0046903 147 0.031
multicellular organismal reproductive behavior GO:0033057 384 0.031
macromolecule biosynthetic process GO:0009059 250 0.031
regulation of gene expression epigenetic GO:0040029 163 0.030
dna metabolic process GO:0006259 74 0.030
organophosphate metabolic process GO:0019637 125 0.030
regulation of organelle organization GO:0033043 164 0.029
cellular component movement GO:0006928 388 0.029
purine nucleoside triphosphate metabolic process GO:0009144 87 0.029
post embryonic organ development GO:0048569 336 0.028
positive regulation of multicellular organismal process GO:0051240 417 0.028
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.028
biosynthetic process GO:0009058 323 0.028
regulation of molecular function GO:0065009 89 0.028
nucleobase containing compound catabolic process GO:0034655 114 0.028
small molecule metabolic process GO:0044281 186 0.028
signaling GO:0023052 401 0.027
regulation of catalytic activity GO:0050790 78 0.027
nucleobase containing small molecule metabolic process GO:0055086 115 0.027
digestive system development GO:0055123 122 0.026
regulation of signaling GO:0023051 172 0.026
behavior GO:0007610 527 0.026
carboxylic acid metabolic process GO:0019752 34 0.026
regulation of catabolic process GO:0009894 57 0.026
ribose phosphate metabolic process GO:0019693 99 0.026
positive regulation of rna metabolic process GO:0051254 103 0.026
ribonucleoside catabolic process GO:0042454 77 0.026
negative regulation of biosynthetic process GO:0009890 65 0.026
single organism catabolic process GO:0044712 129 0.025
ribonucleotide metabolic process GO:0009259 99 0.025
positive regulation of transcription dna templated GO:0045893 102 0.024
protein modification by small protein conjugation or removal GO:0070647 40 0.024
microtubule polymerization or depolymerization GO:0031109 22 0.024
multi multicellular organism process GO:0044706 390 0.024
ribonucleoprotein complex assembly GO:0022618 4 0.024
dna templated transcription elongation GO:0006354 1 0.024
generation of neurons GO:0048699 235 0.024
nucleoside catabolic process GO:0009164 78 0.024
purine containing compound metabolic process GO:0072521 95 0.023
rna interference GO:0016246 137 0.023
establishment of nucleus localization GO:0040023 55 0.023
neuron development GO:0048666 199 0.023
cellular amino acid metabolic process GO:0006520 15 0.023
positive regulation of cellular biosynthetic process GO:0031328 109 0.023
taxis GO:0042330 128 0.023
oogenesis GO:0048477 229 0.022
autophagy GO:0006914 29 0.022
purine nucleoside metabolic process GO:0042278 92 0.022
oocyte axis specification GO:0007309 2 0.022
chromatin modification GO:0016568 32 0.022
oocyte construction GO:0007308 2 0.022
centrosomal and pronuclear rotation GO:0035047 6 0.022
response to wounding GO:0009611 4 0.022
organic substance transport GO:0071702 113 0.022
ribonucleoside triphosphate metabolic process GO:0009199 87 0.021
nucleoside triphosphate catabolic process GO:0009143 72 0.021
striated muscle cell development GO:0055002 157 0.021
cellular nitrogen compound catabolic process GO:0044270 119 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 222 0.020
dna templated transcription initiation GO:0006352 3 0.020
intracellular signal transduction GO:0035556 96 0.020
signal transduction GO:0007165 317 0.020
ribonucleotide catabolic process GO:0009261 75 0.020
mitotic nuclear division GO:0007067 89 0.020
carbohydrate derivative metabolic process GO:1901135 141 0.020
positive regulation of catalytic activity GO:0043085 59 0.020
meiotic nuclear division GO:0007126 300 0.019
guanosine containing compound catabolic process GO:1901069 48 0.019
striated muscle cell differentiation GO:0051146 158 0.019
regulation of nitrogen compound metabolic process GO:0051171 222 0.019
dna repair GO:0006281 23 0.019
negative regulation of gene expression GO:0010629 217 0.019
regulation of protein ubiquitination GO:0031396 3 0.018
organonitrogen compound catabolic process GO:1901565 90 0.018
nucleotide catabolic process GO:0009166 77 0.018
rna metabolic process GO:0016070 228 0.018
muscle cell differentiation GO:0042692 171 0.017
cellular macromolecule localization GO:0070727 75 0.017
system process GO:0003008 136 0.017
cellular response to chemical stimulus GO:0070887 129 0.017
muscle structure development GO:0061061 191 0.017
response to organic substance GO:0010033 131 0.017
regulation of multicellular organismal development GO:2000026 317 0.017
carbohydrate derivative catabolic process GO:1901136 82 0.017
chromatin organization GO:0006325 32 0.017
regulation of response to stimulus GO:0048583 243 0.017
regulation of jun kinase activity GO:0043506 3 0.016
glycosyl compound catabolic process GO:1901658 79 0.016
regulation of signal transduction GO:0009966 135 0.016
nucleoside phosphate metabolic process GO:0006753 108 0.016
oxidation reduction process GO:0055114 59 0.016
chemotaxis GO:0006935 120 0.016
positive regulation of intracellular signal transduction GO:1902533 24 0.016
regulation of phosphorus metabolic process GO:0051174 81 0.016
cell type specific apoptotic process GO:0097285 4 0.016
myosin filament organization GO:0031033 138 0.016
gene silencing by rna GO:0031047 143 0.016
amine metabolic process GO:0009308 15 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
head development GO:0060322 1 0.016
purine nucleoside catabolic process GO:0006152 75 0.016
posttranscriptional gene silencing GO:0016441 143 0.015
male sex differentiation GO:0046661 86 0.015
regulation of cell division GO:0051302 142 0.015
actomyosin structure organization GO:0031032 154 0.015
cellular protein localization GO:0034613 75 0.015
purine ribonucleoside metabolic process GO:0046128 92 0.015
response to inorganic substance GO:0010035 50 0.015
proteasome assembly GO:0043248 1 0.014
cellular amine metabolic process GO:0044106 15 0.014
muscle cell development GO:0055001 158 0.014
myosin filament assembly GO:0031034 138 0.014
organophosphate catabolic process GO:0046434 81 0.014
striated muscle myosin thick filament assembly GO:0071688 138 0.014
regulation of phosphate metabolic process GO:0019220 81 0.014
nuclear migration GO:0007097 54 0.014
negative regulation of cellular metabolic process GO:0031324 95 0.014
organic acid metabolic process GO:0006082 47 0.014
regulation of intracellular signal transduction GO:1902531 77 0.014
multi organism reproductive behavior GO:0044705 387 0.014
negative regulation of response to stimulus GO:0048585 73 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 1 0.014
nucleus localization GO:0051647 55 0.013
purine ribonucleotide catabolic process GO:0009154 75 0.013
regulation of cell communication GO:0010646 176 0.013
mitotic sister chromatid segregation GO:0000070 38 0.013
regulation of cell cycle GO:0051726 194 0.013
establishment of protein localization GO:0045184 50 0.013
gene silencing GO:0016458 143 0.013
nucleoside triphosphate metabolic process GO:0009141 87 0.013
positive regulation of chromosome organization GO:2001252 2 0.013
protein dna complex subunit organization GO:0071824 7 0.013
multi organism behavior GO:0051705 389 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
oxoacid metabolic process GO:0043436 47 0.012
peptidyl amino acid modification GO:0018193 58 0.012
neuron projection development GO:0031175 187 0.012
purine ribonucleoside catabolic process GO:0046130 75 0.012
axon development GO:0061564 163 0.012
organic cyclic compound catabolic process GO:1901361 119 0.012
protein oligomerization GO:0051259 4 0.011
actin cytoskeleton organization GO:0030036 184 0.011
protein localization to endoplasmic reticulum GO:0070972 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 149 0.011
response to abiotic stimulus GO:0009628 152 0.011
response to temperature stimulus GO:0009266 66 0.011
purine containing compound catabolic process GO:0072523 75 0.011
purine nucleoside triphosphate catabolic process GO:0009146 72 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
protein localization to organelle GO:0033365 37 0.011
microtubule polymerization GO:0046785 16 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
ribonucleoside metabolic process GO:0009119 98 0.011
positive regulation of protein complex assembly GO:0031334 6 0.011
purine nucleotide metabolic process GO:0006163 95 0.011
positive regulation of phosphorus metabolic process GO:0010562 56 0.011
gtp metabolic process GO:0046039 46 0.011
phosphorylation GO:0016310 116 0.010
purine ribonucleotide metabolic process GO:0009150 95 0.010
inductive cell migration GO:0040039 145 0.010
nucleoside monophosphate metabolic process GO:0009123 46 0.010

rpn-12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org