Caenorhabditis elegans

2 known processes

sulp-8 (CELE_ZK287.2)

Protein SULP-8

sulp-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 2992 0.329
post embryonic development GO:0009791 2152 0.297
embryo development GO:0009790 3052 0.288
single organism localization GO:1902578 518 0.211
Zebrafish Mouse
negative regulation of biological process GO:0048519 567 0.206
multicellular organism reproduction GO:0032504 819 0.205
Mouse
multicellular organismal reproductive behavior GO:0033057 384 0.195
cell motility GO:0048870 313 0.187
regulation of transcription from rna polymerase ii promoter GO:0006357 145 0.185
organ development GO:0048513 1102 0.171
regulation of multicellular organismal process GO:0051239 726 0.169
endocytosis GO:0006897 819 0.165
vesicle mediated transport GO:0016192 852 0.163
locomotion GO:0040011 1634 0.157
multicellular organismal aging GO:0010259 812 0.156
cellular component movement GO:0006928 388 0.153
establishment of localization GO:0051234 1171 0.152
Zebrafish Mouse
muscle tissue development GO:0060537 1 0.145
single organism transport GO:0044765 447 0.142
Zebrafish Mouse
oviposition GO:0018991 364 0.136
single organism reproductive process GO:0044702 1196 0.135
Mouse
regulation of multicellular organismal development GO:2000026 317 0.131
apoptotic process GO:0006915 478 0.128
cell migration GO:0016477 306 0.127
regulation of cell migration GO:0030334 55 0.117
multi organism reproductive behavior GO:0044705 387 0.117
transport GO:0006810 1093 0.115
Zebrafish Mouse
programmed cell death GO:0012501 500 0.114
multicellular organismal reproductive process GO:0048609 815 0.114
Mouse
multi organism reproductive process GO:0044703 867 0.113
Mouse
regulation of locomotion GO:0040012 161 0.113
cellular component morphogenesis GO:0032989 318 0.111
positive regulation of multicellular organismal process GO:0051240 417 0.110
cell cycle GO:0007049 526 0.110
reproductive system development GO:0061458 850 0.108
localization of cell GO:0051674 313 0.107
protein metabolic process GO:0019538 422 0.106
cell development GO:0048468 696 0.106
Mouse
growth GO:0040007 562 0.105
macromolecule localization GO:0033036 771 0.104
Mouse
receptor mediated endocytosis GO:0006898 715 0.102
organelle organization GO:0006996 783 0.101
striated muscle cell differentiation GO:0051146 158 0.101
negative regulation of metabolic process GO:0009892 240 0.099
reproductive behavior GO:0019098 387 0.099
multi multicellular organism process GO:0044706 390 0.098
aging GO:0007568 812 0.097
cytoskeleton organization GO:0007010 339 0.096
regulation of synapse assembly GO:0051963 2 0.095
developmental process involved in reproduction GO:0003006 1165 0.092
Mouse
regulation of developmental process GO:0050793 684 0.090
multi organism behavior GO:0051705 389 0.089
regulation of biological quality GO:0065008 741 0.087
Zebrafish Mouse
cell fate commitment GO:0045165 139 0.086
digestive tract development GO:0048565 122 0.084
development of primary sexual characteristics GO:0045137 840 0.080
positive regulation of developmental process GO:0051094 408 0.080
cell death GO:0008219 547 0.078
gonad development GO:0008406 840 0.078
cellular component assembly GO:0022607 293 0.077
cell morphogenesis GO:0000902 163 0.077
reproductive structure development GO:0048608 850 0.077
catabolic process GO:0009056 318 0.077
negative regulation of macromolecule metabolic process GO:0010605 229 0.076
determination of adult lifespan GO:0008340 812 0.076
regulation of developmental growth GO:0048638 389 0.076
lipid localization GO:0010876 573 0.074
positive regulation of developmental growth GO:0048639 354 0.074
regulation of vulval development GO:0040028 248 0.072
generation of neurons GO:0048699 235 0.071
hermaphrodite genitalia development GO:0040035 734 0.071
defense response GO:0006952 296 0.069
lipid storage GO:0019915 565 0.067
behavior GO:0007610 527 0.064
regulation of growth GO:0040008 409 0.064
positive regulation of growth GO:0045927 369 0.064
maintenance of location GO:0051235 580 0.063
muscle cell differentiation GO:0042692 171 0.062
sexual reproduction GO:0019953 546 0.062
Mouse
cellular localization GO:0051641 360 0.061
regulation of metabolic process GO:0019222 478 0.060
meiotic cell cycle GO:0051321 335 0.058
negative regulation of nematode larval development GO:0061064 208 0.058
neurogenesis GO:0022008 236 0.058
genitalia development GO:0048806 741 0.058
death GO:0016265 547 0.056
positive regulation of cellular metabolic process GO:0031325 178 0.056
single organism organelle organization GO:1902589 501 0.056
organic substance biosynthetic process GO:1901576 323 0.056
positive regulation of multicellular organism growth GO:0040018 352 0.055
regulation of cellular metabolic process GO:0031323 305 0.055
neuron differentiation GO:0030182 217 0.054
response to organic substance GO:0010033 131 0.054
Mouse
protein complex subunit organization GO:0071822 280 0.054
regulation of multicellular organism growth GO:0040014 373 0.053
sex differentiation GO:0007548 909 0.052
regulation of cellular component organization GO:0051128 248 0.050
embryonic morphogenesis GO:0048598 152 0.050
positive regulation of metabolic process GO:0009893 187 0.050
cellular biosynthetic process GO:0044249 315 0.050
establishment of localization in cell GO:0051649 318 0.049
negative regulation of gene expression GO:0010629 217 0.049
developmental growth GO:0048589 412 0.048
regulation of macromolecule metabolic process GO:0060255 421 0.047
multicellular organism growth GO:0035264 385 0.047
vulval development GO:0040025 333 0.047
response to wounding GO:0009611 4 0.046
cell division GO:0051301 262 0.046
biosynthetic process GO:0009058 323 0.045
muscle cell development GO:0055001 158 0.044
negative regulation of multicellular organismal process GO:0051241 236 0.044
macromolecular complex subunit organization GO:0043933 320 0.044
organelle fission GO:0048285 363 0.044
cell morphogenesis involved in neuron differentiation GO:0048667 111 0.044
striated muscle cell development GO:0055002 157 0.044
anatomical structure formation involved in morphogenesis GO:0048646 250 0.044
positive regulation of cellular process GO:0048522 332 0.043
Mouse
skeletal muscle organ development GO:0060538 3 0.042
single organism biosynthetic process GO:0044711 91 0.042
lipid biosynthetic process GO:0008610 28 0.041
regulation of post embryonic development GO:0048580 260 0.041
regulation of cell cycle GO:0051726 194 0.041
digestive system development GO:0055123 122 0.041
cell morphogenesis involved in differentiation GO:0000904 112 0.041
cell cycle process GO:0022402 482 0.040
organic substance catabolic process GO:1901575 294 0.039
macromolecular complex assembly GO:0065003 193 0.039
muscle structure development GO:0061061 191 0.039
cellular component biogenesis GO:0044085 297 0.038
molting cycle GO:0042303 281 0.038
monocarboxylic acid biosynthetic process GO:0072330 13 0.038
phosphorus metabolic process GO:0006793 232 0.037
regulation of primary metabolic process GO:0080090 292 0.037
regulation of cellular component movement GO:0051270 62 0.036
regulation of localization GO:0032879 194 0.036
Mouse
rna biosynthetic process GO:0032774 169 0.036
eating behavior GO:0042755 59 0.035
intracellular receptor signaling pathway GO:0030522 2 0.035
body morphogenesis GO:0010171 620 0.034
single organism cellular localization GO:1902580 72 0.034
macromolecule biosynthetic process GO:0009059 250 0.034
transcription from rna polymerase ii promoter GO:0006366 149 0.034
regulation of nematode larval development GO:0061062 260 0.034
system process GO:0003008 136 0.033
Mouse
small molecule biosynthetic process GO:0044283 38 0.033
neuron development GO:0048666 199 0.033
response to external stimulus GO:0009605 289 0.033
response to acid chemical GO:0001101 4 0.032
cellular component assembly involved in morphogenesis GO:0010927 183 0.032
epithelial cell proliferation GO:0050673 1 0.032
cell projection morphogenesis GO:0048858 148 0.032
carboxylic acid biosynthetic process GO:0046394 21 0.031
protein modification process GO:0036211 207 0.031
axon guidance GO:0007411 82 0.031
organonitrogen compound biosynthetic process GO:1901566 44 0.031
regulation of gene expression GO:0010468 366 0.031
response to chemical GO:0042221 356 0.030
Mouse
tissue development GO:0009888 112 0.030
protein complex biogenesis GO:0070271 186 0.029
neuromuscular junction development GO:0007528 2 0.029
actin cytoskeleton organization GO:0030036 184 0.028
protein complex assembly GO:0006461 186 0.028
cell part morphogenesis GO:0032990 152 0.028
actin filament based process GO:0030029 191 0.028
negative regulation of post embryonic development GO:0048581 208 0.028
cuticle development GO:0042335 100 0.027
protein localization GO:0008104 205 0.027
Mouse
phosphate containing compound metabolic process GO:0006796 232 0.027
cell type specific apoptotic process GO:0097285 4 0.027
negative regulation of cellular metabolic process GO:0031324 95 0.027
regulation of reproductive process GO:2000241 66 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.027
defense response to bacterium GO:0042742 86 0.027
regulation of behavior GO:0050795 97 0.027
organelle assembly GO:0070925 214 0.026
cell cell signaling GO:0007267 118 0.026
cellular catabolic process GO:0044248 199 0.026
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.026
neuron projection morphogenesis GO:0048812 114 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 45 0.026
regulation of cell proliferation GO:0042127 105 0.026
nucleobase containing compound metabolic process GO:0006139 406 0.025
head development GO:0060322 1 0.025
macromolecule modification GO:0043412 218 0.025
negative regulation of cellular process GO:0048523 239 0.025
negative regulation of developmental process GO:0051093 227 0.025
organonitrogen compound metabolic process GO:1901564 151 0.025
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.025
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 188 0.025
cellular macromolecule biosynthetic process GO:0034645 247 0.025
secretion GO:0046903 147 0.024
Mouse
meiotic nuclear division GO:0007126 300 0.024
aromatic compound biosynthetic process GO:0019438 192 0.024
carboxylic acid metabolic process GO:0019752 34 0.024
cell fate commitment involved in formation of primary germ layer GO:0060795 33 0.024
endodermal cell fate determination GO:0007493 2 0.023
post embryonic organ development GO:0048569 336 0.023
positive regulation of organ growth GO:0046622 4 0.023
regulation of transport GO:0051049 91 0.023
Mouse
regulation of multi organism process GO:0043900 69 0.023
organ morphogenesis GO:0009887 67 0.023
axon development GO:0061564 163 0.022
defense response to other organism GO:0098542 100 0.022
myofibril assembly GO:0030239 154 0.022
actomyosin structure organization GO:0031032 154 0.022
acetylcholine metabolic process GO:0008291 4 0.022
adult locomotory behavior GO:0008344 1 0.021
regulation of lipid metabolic process GO:0019216 4 0.021
organic substance transport GO:0071702 113 0.021
Zebrafish Mouse
gene expression GO:0010467 412 0.021
regulation of epithelial cell proliferation GO:0050678 1 0.021
regulation of cell differentiation GO:0045595 81 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 134 0.021
regulation of bmp signaling pathway GO:0030510 3 0.021
single organism catabolic process GO:0044712 129 0.021
signaling GO:0023052 401 0.020
Mouse
cell substrate adhesion GO:0031589 1 0.020
cellular protein modification process GO:0006464 207 0.020
nucleobase containing compound biosynthetic process GO:0034654 184 0.020
regulation of organ morphogenesis GO:2000027 4 0.020
cellular protein complex assembly GO:0043623 178 0.020
small molecule metabolic process GO:0044281 186 0.020
gamete generation GO:0007276 461 0.020
Mouse
detection of external stimulus GO:0009581 4 0.019
striated muscle myosin thick filament assembly GO:0071688 138 0.019
sensory organ morphogenesis GO:0090596 2 0.019
secretion by cell GO:0032940 138 0.019
regulation of biosynthetic process GO:0009889 189 0.019
lipid metabolic process GO:0006629 77 0.018
autophagy GO:0006914 29 0.018
regulation of phosphorus metabolic process GO:0051174 81 0.018
fatty acid biosynthetic process GO:0006633 10 0.018
gene silencing GO:0016458 143 0.018
neuron projection development GO:0031175 187 0.018
positive regulation of locomotion GO:0040017 42 0.018
detection of abiotic stimulus GO:0009582 4 0.018
intracellular signal transduction GO:0035556 96 0.018
Mouse
nervous system development GO:0007399 253 0.018
myosin filament assembly GO:0031034 138 0.017
positive regulation of molecular function GO:0044093 61 0.017
nitrogen compound transport GO:0071705 49 0.017
Mouse
regulation of nucleocytoplasmic transport GO:0046822 3 0.017
regulation of intracellular signal transduction GO:1902531 77 0.017
establishment of protein localization to membrane GO:0090150 3 0.017
pharyngeal pumping GO:0043050 58 0.017
positive regulation of catalytic activity GO:0043085 59 0.017
regulation of gene expression epigenetic GO:0040029 163 0.017
organic acid metabolic process GO:0006082 47 0.017
positive regulation of cellular biosynthetic process GO:0031328 109 0.017
gene silencing by rna GO:0031047 143 0.017
covalent chromatin modification GO:0016569 30 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 65 0.016
intracellular transport GO:0046907 77 0.016
regulation of apoptotic signaling pathway GO:2001233 1 0.016
regulation of transcription dna templated GO:0006355 164 0.016
heterocycle biosynthetic process GO:0018130 187 0.016
germ cell development GO:0007281 351 0.016
Mouse
cell projection organization GO:0030030 231 0.016
axonogenesis GO:0007409 102 0.016
organophosphate metabolic process GO:0019637 125 0.016
dauer larval development GO:0040024 92 0.016
single organism behavior GO:0044708 83 0.016
phosphorylation GO:0016310 116 0.016
regulation of organelle organization GO:0033043 164 0.016
regulation of hormone secretion GO:0046883 2 0.016
phagocytosis GO:0006909 115 0.016
cellular protein metabolic process GO:0044267 279 0.016
amine metabolic process GO:0009308 15 0.016
regulation of catalytic activity GO:0050790 78 0.016
carbohydrate metabolic process GO:0005975 34 0.015
cellular response to oxygen containing compound GO:1901701 21 0.015
Mouse
synaptic growth at neuromuscular junction GO:0051124 1 0.015
adult behavior GO:0030534 3 0.015
cellular response to organic substance GO:0071310 119 0.015
Mouse
regulation of response to stimulus GO:0048583 243 0.015
inductive cell migration GO:0040039 145 0.015
regulation of gastrulation GO:0010470 4 0.015
single organism signaling GO:0044700 401 0.015
Mouse
tube development GO:0035295 126 0.015
posttranscriptional gene silencing GO:0016441 143 0.015
cellular macromolecular complex assembly GO:0034622 184 0.015
glycoprotein metabolic process GO:0009100 29 0.015
myosin filament organization GO:0031033 138 0.015
regulation of oviposition GO:0046662 43 0.015
positive regulation of phosphate metabolic process GO:0045937 56 0.014
cell proliferation GO:0008283 116 0.014
neuron projection guidance GO:0097485 82 0.014
positive regulation of phosphorus metabolic process GO:0010562 56 0.014
canonical wnt signaling pathway GO:0060070 3 0.014
regulation of molecular function GO:0065009 89 0.014
regulation of cellular protein metabolic process GO:0032268 75 0.014
negative regulation of neurogenesis GO:0050768 4 0.014
positive regulation of biosynthetic process GO:0009891 109 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 98 0.014
digestive tract morphogenesis GO:0048546 76 0.014
nucleic acid metabolic process GO:0090304 299 0.014
positive regulation of transcription dna templated GO:0045893 102 0.014
hormone metabolic process GO:0042445 3 0.014
cellular response to stress GO:0033554 162 0.014
cellular macromolecule localization GO:0070727 75 0.014
negative regulation of bmp signaling pathway GO:0030514 1 0.014
primary sex determination germ line GO:0007542 3 0.014
regulation of rna biosynthetic process GO:2001141 165 0.014
cellular protein localization GO:0034613 75 0.014
sensory perception GO:0007600 27 0.014
negative regulation of biosynthetic process GO:0009890 65 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 63 0.013
positive regulation of intracellular transport GO:0032388 2 0.013
positive regulation of cell migration GO:0030335 3 0.013
negative regulation of neuron differentiation GO:0045665 4 0.013
membrane organization GO:0061024 135 0.013
collagen and cuticulin based cuticle development GO:0040002 99 0.013
regulation of protein targeting GO:1903533 3 0.013
taxis GO:0042330 128 0.013
oxoacid metabolic process GO:0043436 47 0.013
acetate ester metabolic process GO:1900619 4 0.013
rna interference GO:0016246 137 0.013
small gtpase mediated signal transduction GO:0007264 32 0.013
rna metabolic process GO:0016070 228 0.013
regulation of meiotic cell cycle GO:0051445 136 0.013
cell growth GO:0016049 44 0.013
protein oligomerization GO:0051259 4 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
sex determination GO:0007530 60 0.012
posttranscriptional gene silencing by rna GO:0035194 143 0.012
regulation of nucleic acid templated transcription GO:1903506 165 0.012
nematode male tail tip morphogenesis GO:0045138 77 0.012
monocarboxylic acid metabolic process GO:0032787 22 0.012
negative regulation of transcription dna templated GO:0045892 53 0.012
single organism intracellular transport GO:1902582 70 0.012
cellular amine metabolic process GO:0044106 15 0.012
nucleic acid templated transcription GO:0097659 169 0.012
synaptic transmission GO:0007268 106 0.012
regulation of catabolic process GO:0009894 57 0.012
negative regulation of vulval development GO:0040027 206 0.012
regulation of nitrogen compound metabolic process GO:0051171 222 0.012
neuron apoptotic process GO:0051402 4 0.012
regulation of cytoplasmic transport GO:1903649 3 0.012
gastrulation GO:0007369 58 0.012
positive regulation of rna biosynthetic process GO:1902680 102 0.012
axonal fasciculation GO:0007413 79 0.012
negative regulation of signaling GO:0023057 61 0.011
regeneration GO:0031099 4 0.011
calcium mediated signaling GO:0019722 3 0.011
cellular response to chemical stimulus GO:0070887 129 0.011
Mouse
cell matrix adhesion GO:0007160 1 0.011
bmp signaling pathway GO:0030509 3 0.011
cellular amino acid metabolic process GO:0006520 15 0.011
negative regulation of signal transduction GO:0009968 60 0.011
posttranscriptional regulation of gene expression GO:0010608 166 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.011
regulation of cell communication GO:0010646 176 0.011
muscle organ morphogenesis GO:0048644 4 0.011
cellular nitrogen compound biosynthetic process GO:0044271 192 0.011
positive regulation of rna metabolic process GO:0051254 103 0.011
female gamete generation GO:0007292 254 0.011
ion transmembrane transport GO:0034220 91 0.011
Zebrafish Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
regulation of programmed cell death GO:0043067 50 0.011
response to extracellular stimulus GO:0009991 38 0.011
negative regulation of rna biosynthetic process GO:1902679 53 0.011
response to abiotic stimulus GO:0009628 152 0.011
Zebrafish
apoptotic cell clearance GO:0043277 111 0.011
oogenesis GO:0048477 229 0.011
chemotaxis GO:0006935 120 0.011
ras protein signal transduction GO:0007265 31 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 65 0.011
positive regulation of gene expression GO:0010628 112 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
negative regulation of rna metabolic process GO:0051253 53 0.010
single organism carbohydrate metabolic process GO:0044723 29 0.010
carbohydrate derivative metabolic process GO:1901135 141 0.010
microtubule based process GO:0007017 182 0.010
peptidyl tyrosine phosphorylation GO:0018108 2 0.010
cellular lipid metabolic process GO:0044255 40 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
lipid modification GO:0030258 4 0.010
response to starvation GO:0042594 26 0.010
feeding behavior GO:0007631 70 0.010
negative regulation of response to stimulus GO:0048585 73 0.010
macromolecule catabolic process GO:0009057 202 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010

sulp-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.038
disease of anatomical entity DOID:7 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011
nervous system disease DOID:863 0 0.010