Caenorhabditis elegans

41 known processes

clc-3 (CELE_ZK563.4)

Protein CLC-3

clc-3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cation channel activity GO:2001258 2 0.443
embryo development ending in birth or egg hatching GO:0009792 2992 0.333
locomotion GO:0040011 1634 0.300
post embryonic development GO:0009791 2152 0.297
protein metabolic process GO:0019538 422 0.279
organ development GO:0048513 1102 0.232
positive regulation of multicellular organismal process GO:0051240 417 0.219
reproductive structure development GO:0048608 850 0.212
reproductive system development GO:0061458 850 0.199
single organism reproductive process GO:0044702 1196 0.197
multicellular organism reproduction GO:0032504 819 0.189
gamete generation GO:0007276 461 0.180
regulation of multicellular organismal process GO:0051239 726 0.164
determination of adult lifespan GO:0008340 812 0.161
multi organism reproductive process GO:0044703 867 0.157
aging GO:0007568 812 0.155
cell development GO:0048468 696 0.148
growth GO:0040007 562 0.142
developmental process involved in reproduction GO:0003006 1165 0.138
multicellular organismal aging GO:0010259 812 0.138
regulation of signaling GO:0023051 172 0.129
receptor mediated endocytosis GO:0006898 715 0.127
sex differentiation GO:0007548 909 0.125
gonad development GO:0008406 840 0.120
hermaphrodite genitalia development GO:0040035 734 0.105
endoplasmic reticulum unfolded protein response GO:0030968 66 0.105
cellular response to topologically incorrect protein GO:0035967 76 0.104
development of primary sexual characteristics GO:0045137 840 0.102
positive regulation of developmental process GO:0051094 408 0.102
multi multicellular organism process GO:0044706 390 0.099
protein catabolic process GO:0030163 162 0.098
regulation of growth GO:0040008 409 0.097
regulation of developmental process GO:0050793 684 0.097
multicellular organismal reproductive process GO:0048609 815 0.095
behavior GO:0007610 527 0.090
positive regulation of growth GO:0045927 369 0.088
lipid localization GO:0010876 573 0.084
lipid storage GO:0019915 565 0.080
developmental growth GO:0048589 412 0.080
negative regulation of biological process GO:0048519 567 0.079
regulation of biological quality GO:0065008 741 0.078
organic substance biosynthetic process GO:1901576 323 0.077
oviposition GO:0018991 364 0.076
regulation of multicellular organism growth GO:0040014 373 0.075
multicellular organism growth GO:0035264 385 0.075
intercellular transport GO:0010496 1 0.075
cell cycle process GO:0022402 482 0.074
positive regulation of cellular process GO:0048522 332 0.073
regulation of metabolic process GO:0019222 478 0.072
maintenance of location GO:0051235 580 0.070
multi organism reproductive behavior GO:0044705 387 0.070
regulation of response to stimulus GO:0048583 243 0.069
macromolecule localization GO:0033036 771 0.069
cellular response to unfolded protein GO:0034620 71 0.068
reproductive behavior GO:0019098 387 0.066
inactivation of mapkkk activity GO:0051390 2 0.065
catabolic process GO:0009056 318 0.064
response to chemical GO:0042221 356 0.064
establishment of localization GO:0051234 1171 0.064
organelle fission GO:0048285 363 0.063
sexual reproduction GO:0019953 546 0.059
organic substance catabolic process GO:1901575 294 0.058
single organism signaling GO:0044700 401 0.057
germ cell development GO:0007281 351 0.057
regulation of developmental growth GO:0048638 389 0.055
feeding behavior GO:0007631 70 0.055
positive regulation of multicellular organism growth GO:0040018 352 0.055
organelle localization GO:0051640 127 0.055
signaling GO:0023052 401 0.054
meiotic cell cycle GO:0051321 335 0.053
cellular process involved in reproduction in multicellular organism GO:0022412 351 0.053
regulation of macromolecule metabolic process GO:0060255 421 0.052
transport GO:0006810 1093 0.051
regulation of behavior GO:0050795 97 0.049
macromolecule catabolic process GO:0009057 202 0.049
phosphate containing compound metabolic process GO:0006796 232 0.047
genitalia development GO:0048806 741 0.047
establishment of localization in cell GO:0051649 318 0.047
cellular response to chemical stimulus GO:0070887 129 0.046
response to topologically incorrect protein GO:0035966 82 0.046
response to abiotic stimulus GO:0009628 152 0.046
positive regulation of developmental growth GO:0048639 354 0.045
cell cycle GO:0007049 526 0.044
embryo development GO:0009790 3052 0.042
regulation of primary metabolic process GO:0080090 292 0.042
single organism organelle organization GO:1902589 501 0.041
response to unfolded protein GO:0006986 71 0.041
regulation of cell communication GO:0010646 176 0.040
er nucleus signaling pathway GO:0006984 66 0.040
negative regulation of transporter activity GO:0032410 3 0.040
regulation of multi organism process GO:0043900 69 0.040
negative regulation of response to stimulus GO:0048585 73 0.039
establishment of nucleus localization GO:0040023 55 0.038
programmed cell death GO:0012501 500 0.038
apoptotic process GO:0006915 478 0.037
cellular response to organic substance GO:0071310 119 0.037
cytoskeleton organization GO:0007010 339 0.037
multi organism behavior GO:0051705 389 0.037
oogenesis GO:0048477 229 0.037
cellular protein metabolic process GO:0044267 279 0.036
protein localization GO:0008104 205 0.036
organelle organization GO:0006996 783 0.035
endocytosis GO:0006897 819 0.035
cell death GO:0008219 547 0.035
single organism behavior GO:0044708 83 0.034
regulation of reproductive process GO:2000241 66 0.033
secretion by cell GO:0032940 138 0.033
body morphogenesis GO:0010171 620 0.032
regulation of cellular metabolic process GO:0031323 305 0.032
meiotic nuclear division GO:0007126 300 0.031
cellular component movement GO:0006928 388 0.031
regulation of locomotion GO:0040012 161 0.030
establishment of organelle localization GO:0051656 123 0.030
multicellular organismal reproductive behavior GO:0033057 384 0.030
regulation of organelle organization GO:0033043 164 0.030
macromolecule modification GO:0043412 218 0.029
negative regulation of ion transmembrane transporter activity GO:0032413 3 0.029
cellular catabolic process GO:0044248 199 0.028
positive regulation of cellular metabolic process GO:0031325 178 0.028
defecation rhythm GO:0035882 3 0.028
female gamete generation GO:0007292 254 0.028
nuclear migration GO:0007097 54 0.028
death GO:0016265 547 0.028
response to external stimulus GO:0009605 289 0.028
monovalent inorganic cation transport GO:0015672 33 0.027
organonitrogen compound metabolic process GO:1901564 151 0.026
fertilization GO:0009566 63 0.026
cell proliferation GO:0008283 116 0.025
response to organic substance GO:0010033 131 0.025
negative regulation of metabolic process GO:0009892 240 0.025
response to endoplasmic reticulum stress GO:0034976 71 0.024
eating behavior GO:0042755 59 0.024
protein phosphorylation GO:0006468 85 0.023
regulation of biosynthetic process GO:0009889 189 0.023
regulation of gene expression GO:0010468 366 0.023
single organism transport GO:0044765 447 0.023
muscle fiber development GO:0048747 2 0.023
regulation of apoptotic signaling pathway GO:2001233 1 0.023
negative regulation of cellular process GO:0048523 239 0.023
regulation of macromolecule biosynthetic process GO:0010556 189 0.022
negative regulation of gene expression GO:0010629 217 0.022
regulation of cation channel activity GO:2001257 3 0.022
regulation of signal transduction GO:0009966 135 0.022
post embryonic organ development GO:0048569 336 0.022
establishment of mitotic spindle orientation GO:0000132 28 0.021
cation transport GO:0006812 78 0.021
negative regulation of ion transmembrane transport GO:0034766 3 0.021
organonitrogen compound catabolic process GO:1901565 90 0.021
protein modification process GO:0036211 207 0.021
sensory organ morphogenesis GO:0090596 2 0.021
epithelial cell proliferation GO:0050673 1 0.021
dauer larval development GO:0040024 92 0.021
cell motility GO:0048870 313 0.020
secretion GO:0046903 147 0.020
regulation of protein metabolic process GO:0051246 81 0.020
response to wounding GO:0009611 4 0.020
vesicle mediated transport GO:0016192 852 0.020
negative regulation of cell communication GO:0010648 61 0.020
head development GO:0060322 1 0.019
neuron projection development GO:0031175 187 0.019
gene expression GO:0010467 412 0.019
regulation of neuromuscular synaptic transmission GO:1900073 1 0.019
regulation of localization GO:0032879 194 0.019
positive regulation of cell migration GO:0030335 3 0.019
establishment of spindle orientation GO:0051294 34 0.018
localization of cell GO:0051674 313 0.018
nucleic acid metabolic process GO:0090304 299 0.018
small molecule metabolic process GO:0044281 186 0.018
regulation of nematode larval development GO:0061062 260 0.018
cell division GO:0051301 262 0.018
positive regulation of biosynthetic process GO:0009891 109 0.017
rna metabolic process GO:0016070 228 0.017
mitotic cell cycle process GO:1903047 194 0.017
molting cycle GO:0042303 281 0.017
biosynthetic process GO:0009058 323 0.016
negative regulation of developmental process GO:0051093 227 0.016
protein complex subunit organization GO:0071822 280 0.016
muscle cell development GO:0055001 158 0.016
cellular ketone metabolic process GO:0042180 14 0.016
negative regulation of macromolecule metabolic process GO:0010605 229 0.016
ion transport GO:0006811 113 0.016
pronuclear migration GO:0035046 51 0.016
inductive cell migration GO:0040039 145 0.016
cellular protein modification process GO:0006464 207 0.016
striated muscle cell development GO:0055002 157 0.016
cytokinesis GO:0000910 80 0.016
regulation of cell death GO:0010941 65 0.016
nucleus localization GO:0051647 55 0.015
regulation of nitrogen compound metabolic process GO:0051171 222 0.015
cell projection organization GO:0030030 231 0.015
aromatic compound catabolic process GO:0019439 116 0.015
male mating behavior GO:0060179 26 0.015
regulation of cell proliferation GO:0042127 105 0.015
intracellular signal transduction GO:0035556 96 0.014
organic cyclic compound biosynthetic process GO:1901362 195 0.014
single organism localization GO:1902578 518 0.014
positive regulation of macromolecule metabolic process GO:0010604 149 0.014
neurological system process GO:0050877 53 0.014
cellular component morphogenesis GO:0032989 318 0.014
phosphorylation GO:0016310 116 0.014
negative regulation of transmembrane transport GO:0034763 3 0.014
cellular nitrogen compound catabolic process GO:0044270 119 0.014
cellular protein catabolic process GO:0044257 37 0.014
spindle organization GO:0007051 92 0.014
erbb signaling pathway GO:0038127 9 0.014
regulation of phosphate metabolic process GO:0019220 81 0.014
meiotic cell cycle process GO:1903046 170 0.014
macromolecule biosynthetic process GO:0009059 250 0.014
cell part morphogenesis GO:0032990 152 0.014
microtubule based process GO:0007017 182 0.014
phosphorus metabolic process GO:0006793 232 0.013
generation of neurons GO:0048699 235 0.013
heterocycle catabolic process GO:0046700 119 0.013
signal transduction GO:0007165 317 0.013
organic substance transport GO:0071702 113 0.013
positive regulation of cell morphogenesis involved in differentiation GO:0010770 4 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
cell morphogenesis GO:0000902 163 0.013
nucleobase containing compound metabolic process GO:0006139 406 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 134 0.013
pharyngeal pumping GO:0043050 58 0.013
response to anesthetic GO:0072347 1 0.013
macromolecular complex subunit organization GO:0043933 320 0.013
regulation of epithelial cell proliferation GO:0050678 1 0.013
transmembrane transport GO:0055085 110 0.012
mechanosensory behavior GO:0007638 25 0.012
regulation of cellular component organization GO:0051128 248 0.012
cellular macromolecule catabolic process GO:0044265 73 0.012
negative regulation of signaling GO:0023057 61 0.012
protein complex biogenesis GO:0070271 186 0.012
negative regulation of multicellular organismal process GO:0051241 236 0.012
cellular biosynthetic process GO:0044249 315 0.012
single organism catabolic process GO:0044712 129 0.012
carbohydrate derivative metabolic process GO:1901135 141 0.011
molting cycle collagen and cuticulin based cuticle GO:0018996 281 0.011
heterocycle biosynthetic process GO:0018130 187 0.011
negative regulation of signal transduction GO:0009968 60 0.011
negative regulation of nematode larval development GO:0061064 208 0.011
positive regulation of gene expression GO:0010628 112 0.011
negative regulation of rna metabolic process GO:0051253 53 0.011
epithelial tube morphogenesis GO:0060562 1 0.011
nematode male tail tip morphogenesis GO:0045138 77 0.011
cellular response to abiotic stimulus GO:0071214 4 0.011
system process GO:0003008 136 0.011
nucleobase containing compound biosynthetic process GO:0034654 184 0.011
establishment of mitotic spindle localization GO:0040001 41 0.011
modification dependent protein catabolic process GO:0019941 32 0.011
ion transmembrane transport GO:0034220 91 0.011
regulation of cellular protein metabolic process GO:0032268 75 0.010
male anatomical structure morphogenesis GO:0090598 78 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 109 0.010
organic cyclic compound catabolic process GO:1901361 119 0.010
adult locomotory behavior GO:0008344 1 0.010
establishment of spindle localization GO:0051293 51 0.010
cell migration GO:0016477 306 0.010
regulation of post embryonic development GO:0048580 260 0.010
lamellipodium assembly GO:0030032 2 0.010

clc-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
cardiovascular system disease DOID:1287 0 0.015