Saccharomyces cerevisiae

131 known processes

RAD5 (YLR032W)

Rad5p

(Aliases: REV2,SNM2)

RAD5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 236 0.999
cellular response to dna damage stimulus GO:0006974 287 0.988
postreplication repair GO:0006301 24 0.951
dna biosynthetic process GO:0071897 33 0.928
error prone translesion synthesis GO:0042276 11 0.887
dna recombination GO:0006310 172 0.833
double strand break repair GO:0006302 105 0.812
recombinational repair GO:0000725 64 0.765
translesion synthesis GO:0019985 16 0.757
double strand break repair via homologous recombination GO:0000724 54 0.734
error free translesion synthesis GO:0070987 9 0.693
telomere organization GO:0032200 75 0.635
nucleotide excision repair GO:0006289 50 0.506
homeostatic process GO:0042592 227 0.495
lagging strand elongation GO:0006273 10 0.470
negative regulation of biosynthetic process GO:0009890 312 0.462
mitotic recombination GO:0006312 55 0.442
meiotic cell cycle GO:0051321 272 0.442
telomere maintenance via recombination GO:0000722 32 0.441
cellular macromolecule catabolic process GO:0044265 363 0.430
regulation of dna metabolic process GO:0051052 100 0.413
telomere maintenance GO:0000723 74 0.403
macromolecule catabolic process GO:0009057 383 0.333
meiotic cell cycle process GO:1903046 229 0.323
regulation of biological quality GO:0065008 391 0.306
dna dependent dna replication GO:0006261 115 0.285
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.273
maintenance of dna repeat elements GO:0043570 20 0.265
heterocycle catabolic process GO:0046700 494 0.261
meiotic nuclear division GO:0007126 163 0.241
organic cyclic compound catabolic process GO:1901361 499 0.228
mitotic sister chromatid cohesion GO:0007064 38 0.226
anatomical structure homeostasis GO:0060249 74 0.218
dna strand elongation involved in dna replication GO:0006271 26 0.216
rna dependent dna replication GO:0006278 25 0.214
meiotic cell cycle checkpoint GO:0033313 10 0.203
cellular nitrogen compound catabolic process GO:0044270 494 0.199
dna strand elongation GO:0022616 29 0.190
double strand break repair via break induced replication GO:0000727 25 0.189
negative regulation of cellular biosynthetic process GO:0031327 312 0.178
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.177
reciprocal dna recombination GO:0035825 54 0.163
nucleoside metabolic process GO:0009116 394 0.156
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.155
reproduction of a single celled organism GO:0032505 191 0.151
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.145
base excision repair GO:0006284 14 0.144
sister chromatid cohesion GO:0007062 49 0.142
negative regulation of rna metabolic process GO:0051253 262 0.140
dna replication GO:0006260 147 0.138
negative regulation of gene expression GO:0010629 312 0.137
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.133
non recombinational repair GO:0000726 33 0.133
negative regulation of nucleic acid templated transcription GO:1903507 260 0.132
purine nucleotide metabolic process GO:0006163 376 0.125
nucleobase containing compound catabolic process GO:0034655 479 0.124
positive regulation of gene expression GO:0010628 321 0.123
purine ribonucleotide metabolic process GO:0009150 372 0.123
purine nucleoside triphosphate catabolic process GO:0009146 329 0.121
meiosis i GO:0007127 92 0.120
aromatic compound catabolic process GO:0019439 491 0.115
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.115
ribonucleoside metabolic process GO:0009119 389 0.112
regulation of dna repair GO:0006282 14 0.110
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.109
chromatin silencing GO:0006342 147 0.107
positive regulation of macromolecule metabolic process GO:0010604 394 0.105
mitochondrion organization GO:0007005 261 0.104
organophosphate catabolic process GO:0046434 338 0.103
chromatin silencing at telomere GO:0006348 84 0.101
nuclear transport GO:0051169 165 0.101
regulation of cellular component organization GO:0051128 334 0.099
reciprocal meiotic recombination GO:0007131 54 0.097
regulation of homeostatic process GO:0032844 19 0.097
telomere maintenance via telomerase GO:0007004 21 0.096
ribonucleoside triphosphate catabolic process GO:0009203 327 0.096
regulation of chromosome organization GO:0033044 66 0.095
ribonucleoside triphosphate metabolic process GO:0009199 356 0.095
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.094
dna replication okazaki fragment processing GO:0033567 7 0.093
single organism catabolic process GO:0044712 619 0.092
developmental process involved in reproduction GO:0003006 159 0.090
developmental process GO:0032502 261 0.088
negative regulation of chromosome organization GO:2001251 39 0.088
ribonucleoside monophosphate metabolic process GO:0009161 265 0.086
nucleotide catabolic process GO:0009166 330 0.085
ribonucleotide metabolic process GO:0009259 377 0.084
double strand break repair via nonhomologous end joining GO:0006303 27 0.084
ribonucleoside catabolic process GO:0042454 332 0.083
purine ribonucleotide catabolic process GO:0009154 327 0.082
purine nucleoside metabolic process GO:0042278 380 0.082
atp metabolic process GO:0046034 251 0.081
protein import GO:0017038 122 0.081
telomere maintenance via telomere lengthening GO:0010833 22 0.079
regulation of organelle organization GO:0033043 243 0.078
carbohydrate derivative catabolic process GO:1901136 339 0.077
dna catabolic process GO:0006308 42 0.075
protein dna complex subunit organization GO:0071824 153 0.074
purine nucleotide catabolic process GO:0006195 328 0.073
purine nucleoside monophosphate metabolic process GO:0009126 262 0.072
negative regulation of cellular metabolic process GO:0031324 407 0.071
dna geometric change GO:0032392 43 0.071
response to chemical GO:0042221 390 0.070
mismatch repair GO:0006298 14 0.069
gene conversion at mating type locus GO:0007534 11 0.068
nucleobase containing small molecule metabolic process GO:0055086 491 0.068
negative regulation of gene expression epigenetic GO:0045814 147 0.067
intracellular protein transport GO:0006886 319 0.066
nuclear division GO:0000280 263 0.065
meiotic mismatch repair GO:0000710 9 0.064
negative regulation of macromolecule metabolic process GO:0010605 375 0.063
monosaccharide metabolic process GO:0005996 83 0.063
anatomical structure morphogenesis GO:0009653 160 0.063
nucleotide metabolic process GO:0009117 453 0.061
nucleoside catabolic process GO:0009164 335 0.061
regulation of dna templated transcription in response to stress GO:0043620 51 0.060
regulation of gene expression epigenetic GO:0040029 147 0.059
cell aging GO:0007569 70 0.058
negative regulation of dna metabolic process GO:0051053 36 0.057
organophosphate metabolic process GO:0019637 597 0.057
purine ribonucleoside metabolic process GO:0046128 380 0.057
ribonucleotide catabolic process GO:0009261 327 0.057
purine nucleoside catabolic process GO:0006152 330 0.056
protein ubiquitination GO:0016567 118 0.055
negative regulation of cell cycle phase transition GO:1901988 59 0.055
negative regulation of dna replication GO:0008156 15 0.054
positive regulation of dna metabolic process GO:0051054 26 0.054
glycosyl compound metabolic process GO:1901657 398 0.054
cellular developmental process GO:0048869 191 0.053
organonitrogen compound catabolic process GO:1901565 404 0.053
establishment of protein localization to organelle GO:0072594 278 0.052
purine ribonucleoside catabolic process GO:0046130 330 0.052
positive regulation of biosynthetic process GO:0009891 336 0.051
positive regulation of cellular biosynthetic process GO:0031328 336 0.051
nucleoside triphosphate catabolic process GO:0009143 329 0.051
meiotic recombination checkpoint GO:0051598 9 0.051
ribose phosphate metabolic process GO:0019693 384 0.051
cellular protein catabolic process GO:0044257 213 0.050
hexose metabolic process GO:0019318 78 0.049
organelle fission GO:0048285 272 0.049
positive regulation of rna biosynthetic process GO:1902680 286 0.048
single organism reproductive process GO:0044702 159 0.048
cell differentiation GO:0030154 161 0.047
response to oxidative stress GO:0006979 99 0.047
protein complex biogenesis GO:0070271 314 0.047
purine nucleoside monophosphate catabolic process GO:0009128 224 0.045
response to uv GO:0009411 4 0.045
carbohydrate derivative metabolic process GO:1901135 549 0.045
protein complex assembly GO:0006461 302 0.045
purine containing compound metabolic process GO:0072521 400 0.045
purine containing compound catabolic process GO:0072523 332 0.045
regulation of cellular catabolic process GO:0031329 195 0.045
glycosyl compound catabolic process GO:1901658 335 0.044
cell cycle phase transition GO:0044770 144 0.044
anatomical structure formation involved in morphogenesis GO:0048646 136 0.043
positive regulation of cellular protein metabolic process GO:0032270 89 0.043
gene silencing GO:0016458 151 0.042
chromatin modification GO:0016568 200 0.042
reproductive process in single celled organism GO:0022413 145 0.042
aging GO:0007568 71 0.041
ribonucleoside monophosphate catabolic process GO:0009158 224 0.040
nucleoside phosphate catabolic process GO:1901292 331 0.040
negative regulation of transcription dna templated GO:0045892 258 0.039
chromosome segregation GO:0007059 159 0.038
regulation of translation GO:0006417 89 0.037
positive regulation of rna metabolic process GO:0051254 294 0.037
regulation of dna dependent dna replication GO:0090329 37 0.036
rna catabolic process GO:0006401 118 0.036
negative regulation of cellular component organization GO:0051129 109 0.036
regulation of cell cycle process GO:0010564 150 0.036
regulation of dna replication GO:0006275 51 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.036
meiotic chromosome segregation GO:0045132 31 0.036
mating type switching GO:0007533 28 0.036
regulation of nuclear division GO:0051783 103 0.036
atp catabolic process GO:0006200 224 0.035
protein localization to nucleus GO:0034504 74 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.035
transposition rna mediated GO:0032197 17 0.035
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.034
regulation of cell cycle GO:0051726 195 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.033
regulation of mitotic cell cycle phase transition GO:1901990 68 0.033
chromatin silencing at silent mating type cassette GO:0030466 53 0.032
negative regulation of rna biosynthetic process GO:1902679 260 0.032
dna double strand break processing GO:0000729 8 0.032
single organism developmental process GO:0044767 258 0.032
phosphorylation GO:0016310 291 0.032
regulation of response to dna damage stimulus GO:2001020 17 0.031
response to organic cyclic compound GO:0014070 1 0.031
cell cycle dna replication GO:0044786 36 0.030
protein targeting GO:0006605 272 0.030
protein catabolic process GO:0030163 221 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.030
dna duplex unwinding GO:0032508 42 0.030
dna catabolic process endonucleolytic GO:0000737 31 0.029
nucleoside monophosphate metabolic process GO:0009123 267 0.028
positive regulation of transcription dna templated GO:0045893 286 0.028
dna replication removal of rna primer GO:0043137 5 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.028
Mouse
gene conversion GO:0035822 14 0.028
negative regulation of mitotic cell cycle GO:0045930 63 0.028
sex determination GO:0007530 32 0.027
regulation of dna recombination GO:0000018 24 0.027
positive regulation of protein metabolic process GO:0051247 93 0.027
negative regulation of cell cycle GO:0045786 91 0.027
negative regulation of meiotic cell cycle GO:0051447 24 0.027
regulation of response to stress GO:0080134 57 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.026
organelle localization GO:0051640 128 0.026
posttranscriptional regulation of gene expression GO:0010608 115 0.025
mitotic cell cycle process GO:1903047 294 0.025
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.025
regulation of transport GO:0051049 85 0.025
positive regulation of nucleic acid templated transcription GO:1903508 286 0.025
purine nucleoside triphosphate metabolic process GO:0009144 356 0.025
regulation of cell cycle g2 m phase transition GO:1902749 8 0.025
regulation of localization GO:0032879 127 0.025
mitotic cell cycle GO:0000278 306 0.025
response to organic substance GO:0010033 182 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.025
regulation of molecular function GO:0065009 320 0.024
replicative cell aging GO:0001302 46 0.024
establishment of mitotic sister chromatid cohesion GO:0034087 15 0.024
regulation of response to stimulus GO:0048583 157 0.024
nucleoside phosphate metabolic process GO:0006753 458 0.024
regulation of mitotic cell cycle GO:0007346 107 0.024
protein dna complex assembly GO:0065004 105 0.023
cell division GO:0051301 205 0.023
dna conformation change GO:0071103 98 0.023
cellular component morphogenesis GO:0032989 97 0.023
response to oxygen containing compound GO:1901700 61 0.023
protein transmembrane transport GO:0071806 82 0.023
ascospore formation GO:0030437 107 0.023
regulation of cellular response to stress GO:0080135 50 0.023
nucleoside monophosphate catabolic process GO:0009125 224 0.022
carboxylic acid metabolic process GO:0019752 338 0.022
protein modification by small protein conjugation or removal GO:0070647 172 0.022
response to abiotic stimulus GO:0009628 159 0.022
negative regulation of homeostatic process GO:0032845 7 0.022
mrna splicing via spliceosome GO:0000398 108 0.022
protein import into nucleus GO:0006606 55 0.022
modification dependent protein catabolic process GO:0019941 181 0.022
nitrogen compound transport GO:0071705 212 0.021
cellular protein complex assembly GO:0043623 209 0.021
cell cycle checkpoint GO:0000075 82 0.021
establishment of sister chromatid cohesion GO:0034085 17 0.021
positive regulation of catabolic process GO:0009896 135 0.021
glucose metabolic process GO:0006006 65 0.021
regulation of cell division GO:0051302 113 0.021
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.021
heteroduplex formation GO:0030491 9 0.021
negative regulation of organelle organization GO:0010639 103 0.021
protein localization to organelle GO:0033365 337 0.021
regulation of phosphate metabolic process GO:0019220 230 0.020
transmembrane transport GO:0055085 349 0.020
sporulation resulting in formation of a cellular spore GO:0030435 129 0.020
regulation of protein metabolic process GO:0051246 237 0.020
transposition GO:0032196 20 0.020
regulation of transposition rna mediated GO:0010525 15 0.020
macromolecule methylation GO:0043414 85 0.020
regulation of mrna splicing via spliceosome GO:0048024 3 0.020
cellular homeostasis GO:0019725 138 0.020
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.020
chromatin organization GO:0006325 242 0.020
double strand break repair via synthesis dependent strand annealing GO:0045003 12 0.019
proteasomal protein catabolic process GO:0010498 141 0.019
multi organism process GO:0051704 233 0.019
nuclear export GO:0051168 124 0.019
nucleocytoplasmic transport GO:0006913 163 0.018
cell morphogenesis GO:0000902 30 0.018
mating type determination GO:0007531 32 0.018
monocarboxylic acid metabolic process GO:0032787 122 0.018
single organism membrane fusion GO:0044801 71 0.018
ion homeostasis GO:0050801 118 0.017
positive regulation of cellular catabolic process GO:0031331 128 0.017
response to drug GO:0042493 41 0.017
carbohydrate metabolic process GO:0005975 252 0.017
response to topologically incorrect protein GO:0035966 38 0.017
telomere capping GO:0016233 10 0.017
positive regulation of catalytic activity GO:0043085 178 0.017
dna recombinase assembly GO:0000730 9 0.017
nucleoside triphosphate metabolic process GO:0009141 364 0.016
mitotic dna damage checkpoint GO:0044773 11 0.016
mrna processing GO:0006397 185 0.016
regulation of rna splicing GO:0043484 3 0.016
cellular chemical homeostasis GO:0055082 123 0.016
positive regulation of response to stimulus GO:0048584 37 0.016
mitochondrion localization GO:0051646 29 0.016
intracellular protein transmembrane transport GO:0065002 80 0.015
g2 m transition of mitotic cell cycle GO:0000086 38 0.015
dna integrity checkpoint GO:0031570 41 0.015
negative regulation of cell cycle process GO:0010948 86 0.015
chromosome organization involved in meiosis GO:0070192 32 0.015
regulation of transposition GO:0010528 16 0.015
cellular component assembly involved in morphogenesis GO:0010927 73 0.015
cellular response to chemical stimulus GO:0070887 315 0.015
cell growth GO:0016049 89 0.015
replication fork protection GO:0048478 6 0.015
single organism nuclear import GO:1902593 56 0.015
mitotic cell cycle phase transition GO:0044772 141 0.014
positive regulation of cell death GO:0010942 3 0.014
positive regulation of cellular component organization GO:0051130 116 0.014
response to nitrogen compound GO:1901698 18 0.014
multi organism reproductive process GO:0044703 216 0.014
rna phosphodiester bond hydrolysis GO:0090501 112 0.014
macroautophagy GO:0016236 55 0.014
positive regulation of phosphorylation GO:0042327 33 0.014
positive regulation of protein modification process GO:0031401 49 0.014
negative regulation of cell division GO:0051782 66 0.014
regulation of protein localization GO:0032880 62 0.014
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.014
positive regulation of cytoplasmic transport GO:1903651 4 0.014
regulation of catabolic process GO:0009894 199 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 2 0.014
positive regulation of cell cycle process GO:0090068 31 0.014
cellular response to oxygen containing compound GO:1901701 43 0.014
regulation of meiosis GO:0040020 42 0.014
cellular component disassembly GO:0022411 86 0.014
regulation of meiotic cell cycle GO:0051445 43 0.013
sexual sporulation GO:0034293 113 0.013
osmosensory signaling pathway GO:0007231 22 0.013
peroxisome organization GO:0007031 68 0.013
cellular response to nitrogen compound GO:1901699 14 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
regulation of cellular protein metabolic process GO:0032268 232 0.013
growth GO:0040007 157 0.013
signal transduction GO:0007165 208 0.013
cellular response to abiotic stimulus GO:0071214 62 0.013
positive regulation of apoptotic process GO:0043065 3 0.013
histone phosphorylation GO:0016572 3 0.013
regulation of establishment of protein localization GO:0070201 17 0.013
cellular response to oxidative stress GO:0034599 94 0.013
chromatin remodeling GO:0006338 80 0.013
positive regulation of organelle organization GO:0010638 85 0.013
protein modification by small protein removal GO:0070646 29 0.012
negative regulation of dna dependent dna replication GO:2000104 8 0.012
regulation of phosphorus metabolic process GO:0051174 230 0.012
histone methylation GO:0016571 28 0.012
mitotic sister chromatid segregation GO:0000070 85 0.012
anatomical structure development GO:0048856 160 0.012
intracellular signal transduction GO:0035556 112 0.012
macromolecular complex disassembly GO:0032984 80 0.012
maintenance of rdna GO:0043007 9 0.012
single organism cellular localization GO:1902580 375 0.012
dna replication initiation GO:0006270 48 0.012
nucleic acid transport GO:0050657 94 0.012
regulation of protein phosphorylation GO:0001932 75 0.012
protein complex localization GO:0031503 32 0.012
cell fate commitment GO:0045165 32 0.012
protein targeting to nucleus GO:0044744 57 0.012
peroxisomal transport GO:0043574 22 0.012
response to hypoxia GO:0001666 4 0.012
nuclear dna replication GO:0033260 27 0.012
protein deacylation GO:0035601 27 0.011
rna export from nucleus GO:0006405 88 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
cellular lipid metabolic process GO:0044255 229 0.011
rna transport GO:0050658 92 0.011
protein transport GO:0015031 345 0.011
protein targeting to mitochondrion GO:0006626 56 0.011
mitotic dna integrity checkpoint GO:0044774 18 0.011
g1 s transition of mitotic cell cycle GO:0000082 64 0.011
response to endogenous stimulus GO:0009719 26 0.011
cellular response to endogenous stimulus GO:0071495 22 0.011
cellular response to organic substance GO:0071310 159 0.011
peptide metabolic process GO:0006518 28 0.011
vesicle organization GO:0016050 68 0.011
negative regulation of meiosis GO:0045835 23 0.011
covalent chromatin modification GO:0016569 119 0.011
programmed cell death GO:0012501 30 0.011
regulation of chromatin silencing GO:0031935 39 0.011
mitotic cell cycle checkpoint GO:0007093 56 0.011
regulation of hydrolase activity GO:0051336 133 0.010
protein polymerization GO:0051258 51 0.010
regulation of catalytic activity GO:0050790 307 0.010
cell cycle g1 s phase transition GO:0044843 64 0.010
nuclear import GO:0051170 57 0.010
histone lysine methylation GO:0034968 26 0.010
mrna metabolic process GO:0016071 269 0.010
budding cell bud growth GO:0007117 29 0.010
positive regulation of molecular function GO:0044093 185 0.010
negative regulation of phosphorus metabolic process GO:0010563 49 0.010
regulation of histone modification GO:0031056 18 0.010
cell budding GO:0007114 48 0.010
regulation of cellular component biogenesis GO:0044087 112 0.010

RAD5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.049
cancer DOID:162 0 0.027
organ system cancer DOID:0050686 0 0.027
disease of anatomical entity DOID:7 0 0.026