Saccharomyces cerevisiae

72 known processes

THO2 (YNL139C)

Tho2p

(Aliases: RLR1,ZRG13,LDB5)

THO2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of rna localization GO:0051236 92 0.897
mrna transport GO:0051028 60 0.896
nitrogen compound transport GO:0071705 212 0.893
nuclear transport GO:0051169 165 0.820
nuclear export GO:0051168 124 0.793
rna export from nucleus GO:0006405 88 0.792
nucleocytoplasmic transport GO:0006913 163 0.790
rna transport GO:0050658 92 0.738
nucleic acid transport GO:0050657 94 0.714
nucleobase containing compound transport GO:0015931 124 0.677
cellular response to dna damage stimulus GO:0006974 287 0.666
rna localization GO:0006403 112 0.652
mrna export from nucleus GO:0006406 60 0.607
dna repair GO:0006281 236 0.600
dna recombination GO:0006310 172 0.472
regulation of biological quality GO:0065008 391 0.444
dna templated transcription elongation GO:0006354 91 0.428
cellular nitrogen compound catabolic process GO:0044270 494 0.423
cellular macromolecule catabolic process GO:0044265 363 0.390
macromolecule catabolic process GO:0009057 383 0.367
rna splicing via transesterification reactions GO:0000375 118 0.356
poly a mrna export from nucleus GO:0016973 24 0.350
nucleoside phosphate metabolic process GO:0006753 458 0.274
mrna processing GO:0006397 185 0.242
nuclear mrna surveillance GO:0071028 22 0.234
single organism catabolic process GO:0044712 619 0.232
regulation of mitotic cell cycle GO:0007346 107 0.230
telomere maintenance GO:0000723 74 0.218
negative regulation of biosynthetic process GO:0009890 312 0.193
negative regulation of macromolecule metabolic process GO:0010605 375 0.188
organophosphate metabolic process GO:0019637 597 0.182
anatomical structure homeostasis GO:0060249 74 0.180
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.167
organic acid metabolic process GO:0006082 352 0.158
purine ribonucleotide metabolic process GO:0009150 372 0.157
hexose metabolic process GO:0019318 78 0.144
nucleobase containing small molecule metabolic process GO:0055086 491 0.135
negative regulation of cell cycle process GO:0010948 86 0.135
rna 3 end processing GO:0031123 88 0.134
carboxylic acid metabolic process GO:0019752 338 0.132
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.132
negative regulation of cell cycle phase transition GO:1901988 59 0.123
telomere organization GO:0032200 75 0.121
organic cyclic compound catabolic process GO:1901361 499 0.121
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.113
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.106
monosaccharide metabolic process GO:0005996 83 0.100
mrna metabolic process GO:0016071 269 0.099
aromatic compound catabolic process GO:0019439 491 0.097
nucleobase containing compound catabolic process GO:0034655 479 0.095
nucleoside phosphate biosynthetic process GO:1901293 80 0.094
protein complex assembly GO:0006461 302 0.093
regulation of mitotic cell cycle phase transition GO:1901990 68 0.091
maintenance of location GO:0051235 66 0.089
organophosphate catabolic process GO:0046434 338 0.089
negative regulation of cellular metabolic process GO:0031324 407 0.087
phosphorylation GO:0016310 291 0.087
dna damage checkpoint GO:0000077 29 0.087
carbohydrate derivative metabolic process GO:1901135 549 0.086
nucleotide metabolic process GO:0009117 453 0.084
ribonucleoside monophosphate metabolic process GO:0009161 265 0.083
nucleotide excision repair GO:0006289 50 0.080
regulation of cell cycle GO:0051726 195 0.080
heterocycle catabolic process GO:0046700 494 0.079
regulation of protein metabolic process GO:0051246 237 0.076
glycosyl compound metabolic process GO:1901657 398 0.075
glucose metabolic process GO:0006006 65 0.075
mitotic cell cycle process GO:1903047 294 0.075
negative regulation of gene expression GO:0010629 312 0.075
double strand break repair GO:0006302 105 0.075
reproduction of a single celled organism GO:0032505 191 0.068
transcription coupled nucleotide excision repair GO:0006283 16 0.067
ribonucleoside catabolic process GO:0042454 332 0.066
cellular response to chemical stimulus GO:0070887 315 0.065
negative regulation of nucleic acid templated transcription GO:1903507 260 0.065
oxoacid metabolic process GO:0043436 351 0.064
cellular component disassembly GO:0022411 86 0.064
regulation of cell cycle phase transition GO:1901987 70 0.061
regulation of molecular function GO:0065009 320 0.059
ribonucleoside metabolic process GO:0009119 389 0.058
mrna 3 end processing GO:0031124 54 0.058
rna surveillance GO:0071025 30 0.058
purine nucleoside monophosphate metabolic process GO:0009126 262 0.056
purine ribonucleoside metabolic process GO:0046128 380 0.056
negative regulation of cellular carbohydrate metabolic process GO:0010677 17 0.056
regulation of cell cycle process GO:0010564 150 0.055
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.054
ribosome biogenesis GO:0042254 335 0.054
nucleoside monophosphate metabolic process GO:0009123 267 0.053
positive regulation of apoptotic process GO:0043065 3 0.053
response to chemical GO:0042221 390 0.053
positive regulation of macromolecule metabolic process GO:0010604 394 0.052
multi organism cellular process GO:0044764 120 0.052
ribonucleoside triphosphate catabolic process GO:0009203 327 0.049
negative regulation of mitotic cell cycle GO:0045930 63 0.049
hexose biosynthetic process GO:0019319 30 0.048
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.048
cell cycle checkpoint GO:0000075 82 0.048
dna integrity checkpoint GO:0031570 41 0.048
reproductive process GO:0022414 248 0.048
rna catabolic process GO:0006401 118 0.046
cellular amino acid metabolic process GO:0006520 225 0.046
purine nucleoside metabolic process GO:0042278 380 0.046
mrna catabolic process GO:0006402 93 0.046
intracellular protein transport GO:0006886 319 0.046
maintenance of location in cell GO:0051651 58 0.045
response to abiotic stimulus GO:0009628 159 0.045
modification dependent macromolecule catabolic process GO:0043632 203 0.045
dna catabolic process GO:0006308 42 0.044
purine nucleoside monophosphate catabolic process GO:0009128 224 0.044
positive regulation of catalytic activity GO:0043085 178 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.043
positive regulation of cell death GO:0010942 3 0.043
negative regulation of transcription dna templated GO:0045892 258 0.042
rrna metabolic process GO:0016072 244 0.042
cellular protein complex assembly GO:0043623 209 0.042
mrna splicing via spliceosome GO:0000398 108 0.041
ribonucleoside monophosphate catabolic process GO:0009158 224 0.041
purine containing compound metabolic process GO:0072521 400 0.040
atp metabolic process GO:0046034 251 0.040
carbohydrate derivative catabolic process GO:1901136 339 0.040
negative regulation of cellular component organization GO:0051129 109 0.040
pyridine containing compound metabolic process GO:0072524 53 0.040
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.039
negative regulation of cell cycle GO:0045786 91 0.039
mitotic cell cycle phase transition GO:0044772 141 0.038
regulation of cellular ketone metabolic process GO:0010565 42 0.038
negative regulation of rna metabolic process GO:0051253 262 0.037
negative regulation of rna biosynthetic process GO:1902679 260 0.037
homeostatic process GO:0042592 227 0.037
purine nucleoside triphosphate metabolic process GO:0009144 356 0.037
ion transport GO:0006811 274 0.036
protein targeting GO:0006605 272 0.036
regulation of cellular catabolic process GO:0031329 195 0.036
nucleoside metabolic process GO:0009116 394 0.036
spliceosomal complex assembly GO:0000245 21 0.035
nuclear transcribed mrna catabolic process GO:0000956 89 0.035
nucleoside triphosphate catabolic process GO:0009143 329 0.035
regulation of catalytic activity GO:0050790 307 0.035
carbohydrate biosynthetic process GO:0016051 82 0.034
monosaccharide biosynthetic process GO:0046364 31 0.034
monocarboxylic acid metabolic process GO:0032787 122 0.034
glycosyl compound catabolic process GO:1901658 335 0.034
reproductive process in single celled organism GO:0022413 145 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.033
mitotic cell cycle checkpoint GO:0007093 56 0.033
regulation of localization GO:0032879 127 0.032
ribose phosphate metabolic process GO:0019693 384 0.032
positive regulation of phosphorus metabolic process GO:0010562 147 0.032
nuclear division GO:0000280 263 0.032
developmental process GO:0032502 261 0.031
response to organic cyclic compound GO:0014070 1 0.030
ribonucleoprotein complex assembly GO:0022618 143 0.030
ribonucleoside triphosphate metabolic process GO:0009199 356 0.030
mating type switching GO:0007533 28 0.030
single organism nuclear import GO:1902593 56 0.030
mitotic recombination GO:0006312 55 0.030
positive regulation of programmed cell death GO:0043068 3 0.030
ribonucleotide metabolic process GO:0009259 377 0.030
positive regulation of dna templated transcription elongation GO:0032786 42 0.030
mitotic cell cycle GO:0000278 306 0.029
establishment of protein localization GO:0045184 367 0.029
positive regulation of molecular function GO:0044093 185 0.029
ribonucleoprotein complex subunit organization GO:0071826 152 0.029
peptidyl amino acid modification GO:0018193 116 0.029
regulation of cellular protein metabolic process GO:0032268 232 0.029
non recombinational repair GO:0000726 33 0.028
protein phosphorylation GO:0006468 197 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.028
macromolecular complex disassembly GO:0032984 80 0.028
regulation of phosphorus metabolic process GO:0051174 230 0.027
atp catabolic process GO:0006200 224 0.027
establishment or maintenance of cell polarity GO:0007163 96 0.027
cellular carbohydrate metabolic process GO:0044262 135 0.027
cellular ketone metabolic process GO:0042180 63 0.027
positive regulation of intracellular transport GO:0032388 4 0.027
regulation of transport GO:0051049 85 0.026
cellular glucan metabolic process GO:0006073 44 0.026
purine nucleotide metabolic process GO:0006163 376 0.026
cellular homeostasis GO:0019725 138 0.026
nucleoside monophosphate catabolic process GO:0009125 224 0.026
single organism developmental process GO:0044767 258 0.026
metal ion transport GO:0030001 75 0.025
oxidation reduction process GO:0055114 353 0.025
protein transport GO:0015031 345 0.025
regulation of dna metabolic process GO:0051052 100 0.025
nucleoside phosphate catabolic process GO:1901292 331 0.024
chromatin organization GO:0006325 242 0.024
protein complex biogenesis GO:0070271 314 0.024
death GO:0016265 30 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
proteolysis GO:0006508 268 0.023
cation transport GO:0006812 166 0.023
mating type determination GO:0007531 32 0.022
conjugation GO:0000746 107 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.022
regulation of protein modification process GO:0031399 110 0.022
regulation of translation GO:0006417 89 0.022
positive regulation of cellular protein metabolic process GO:0032270 89 0.022
negative regulation of carbohydrate metabolic process GO:0045912 17 0.022
purine ribonucleotide catabolic process GO:0009154 327 0.022
microtubule based process GO:0007017 117 0.022
nuclear import GO:0051170 57 0.022
pyruvate metabolic process GO:0006090 37 0.021
developmental process involved in reproduction GO:0003006 159 0.021
cellular developmental process GO:0048869 191 0.021
conjugation with cellular fusion GO:0000747 106 0.021
purine nucleoside catabolic process GO:0006152 330 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.021
regulation of gene expression epigenetic GO:0040029 147 0.021
glycerolipid metabolic process GO:0046486 108 0.021
mitochondrion organization GO:0007005 261 0.020
cell death GO:0008219 30 0.020
positive regulation of transport GO:0051050 32 0.020
purine ribonucleoside catabolic process GO:0046130 330 0.020
regulation of generation of precursor metabolites and energy GO:0043467 23 0.020
positive regulation of intracellular protein transport GO:0090316 3 0.020
nucleoside triphosphate metabolic process GO:0009141 364 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
positive regulation of cellular catabolic process GO:0031331 128 0.019
organonitrogen compound catabolic process GO:1901565 404 0.019
protein polymerization GO:0051258 51 0.019
protein import GO:0017038 122 0.019
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.019
nucleoside catabolic process GO:0009164 335 0.019
positive regulation of hydrolase activity GO:0051345 112 0.018
positive regulation of phosphate metabolic process GO:0045937 147 0.018
chromatin silencing at telomere GO:0006348 84 0.018
positive regulation of cytoplasmic transport GO:1903651 4 0.018
positive regulation of catabolic process GO:0009896 135 0.017
negative regulation of cellular biosynthetic process GO:0031327 312 0.017
cell differentiation GO:0030154 161 0.017
energy reserve metabolic process GO:0006112 32 0.017
purine containing compound catabolic process GO:0072523 332 0.017
chemical homeostasis GO:0048878 137 0.017
generation of precursor metabolites and energy GO:0006091 147 0.017
organonitrogen compound biosynthetic process GO:1901566 314 0.017
glycogen metabolic process GO:0005977 30 0.017
phospholipid metabolic process GO:0006644 125 0.017
glycogen biosynthetic process GO:0005978 17 0.017
regulation of hydrolase activity GO:0051336 133 0.017
nucleotide catabolic process GO:0009166 330 0.016
regulation of rna splicing GO:0043484 3 0.016
termination of rna polymerase ii transcription GO:0006369 26 0.016
cell communication GO:0007154 345 0.016
rna splicing GO:0008380 131 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.016
regulation of protein localization to nucleus GO:1900180 16 0.016
organophosphate biosynthetic process GO:0090407 182 0.016
single organism signaling GO:0044700 208 0.016
cellular bud site selection GO:0000282 35 0.016
apoptotic process GO:0006915 30 0.015
response to organic substance GO:0010033 182 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.015
regulation of cellular component size GO:0032535 50 0.015
energy derivation by oxidation of organic compounds GO:0015980 125 0.015
regulation of phosphate metabolic process GO:0019220 230 0.015
cellular response to abiotic stimulus GO:0071214 62 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.015
cellular protein catabolic process GO:0044257 213 0.015
regulation of cellular amino acid metabolic process GO:0006521 16 0.014
signaling GO:0023052 208 0.014
positive regulation of secretion by cell GO:1903532 2 0.014
regulation of glycogen biosynthetic process GO:0005979 9 0.014
cell cycle phase transition GO:0044770 144 0.014
lipid localization GO:0010876 60 0.014
cytokinesis GO:0000910 92 0.014
dna templated transcription termination GO:0006353 42 0.014
gene silencing GO:0016458 151 0.014
positive regulation of protein metabolic process GO:0051247 93 0.014
single organism reproductive process GO:0044702 159 0.014
cellular carbohydrate biosynthetic process GO:0034637 49 0.014
ribonucleotide catabolic process GO:0009261 327 0.014
amine metabolic process GO:0009308 51 0.014
cell aging GO:0007569 70 0.014
regulation of proteolysis GO:0030162 44 0.014
positive regulation of cell communication GO:0010647 28 0.014
double strand break repair via nonhomologous end joining GO:0006303 27 0.014
regulation of protein complex assembly GO:0043254 77 0.013
maintenance of protein location in cell GO:0032507 50 0.013
cellular amino acid biosynthetic process GO:0008652 118 0.013
chromatin assembly or disassembly GO:0006333 60 0.013
regulation of metal ion transport GO:0010959 2 0.013
external encapsulating structure organization GO:0045229 146 0.013
purine nucleoside triphosphate catabolic process GO:0009146 329 0.013
nucleotide biosynthetic process GO:0009165 79 0.013
protein localization to membrane GO:0072657 102 0.013
cellular component morphogenesis GO:0032989 97 0.013
sex determination GO:0007530 32 0.012
regulation of cell size GO:0008361 30 0.012
regulation of glucan biosynthetic process GO:0010962 11 0.012
regulation of response to stress GO:0080134 57 0.012
cation homeostasis GO:0055080 105 0.012
small molecule biosynthetic process GO:0044283 258 0.012
programmed cell death GO:0012501 30 0.012
regulation of protein targeting GO:1903533 10 0.012
mitotic cytokinesis GO:0000281 58 0.012
protein targeting to nucleus GO:0044744 57 0.012
chromatin silencing at rdna GO:0000183 32 0.012
establishment of cell polarity GO:0030010 64 0.011
regulation of catabolic process GO:0009894 199 0.011
growth GO:0040007 157 0.011
single organism cellular localization GO:1902580 375 0.011
positive regulation of cell cycle GO:0045787 32 0.011
cellular protein complex disassembly GO:0043624 42 0.011
regulation of cell division GO:0051302 113 0.011
alpha amino acid metabolic process GO:1901605 124 0.011
protein catabolic process GO:0030163 221 0.011
cellular cation homeostasis GO:0030003 100 0.011
gluconeogenesis GO:0006094 30 0.011
signal transduction GO:0007165 208 0.011
g2 dna damage checkpoint GO:0031572 1 0.011
regulation of signaling GO:0023051 119 0.011
endomembrane system organization GO:0010256 74 0.011
chromatin assembly GO:0031497 35 0.011
purine nucleotide catabolic process GO:0006195 328 0.011
protein complex disassembly GO:0043241 70 0.011
cellular response to uv GO:0034644 3 0.011
multi organism process GO:0051704 233 0.011
response to oxidative stress GO:0006979 99 0.011
macromolecule methylation GO:0043414 85 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.011
cellular amino acid catabolic process GO:0009063 48 0.011
lipid metabolic process GO:0006629 269 0.011
positive regulation of organelle organization GO:0010638 85 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
response to osmotic stress GO:0006970 83 0.010
regulation of nucleotide metabolic process GO:0006140 110 0.010
regulation of cellular localization GO:0060341 50 0.010
polysaccharide biosynthetic process GO:0000271 39 0.010
modification dependent protein catabolic process GO:0019941 181 0.010
rrna processing GO:0006364 227 0.010
asexual reproduction GO:0019954 48 0.010

THO2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010