Saccharomyces cerevisiae

104 known processes

DED1 (YOR204W)

Ded1p

(Aliases: SPP81)

DED1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 269 0.944
mrna splicing via spliceosome GO:0000398 108 0.840
nuclear transcribed mrna catabolic process GO:0000956 89 0.820
mrna catabolic process GO:0006402 93 0.777
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.695
Human
negative regulation of cellular biosynthetic process GO:0031327 312 0.659
Human
negative regulation of cellular metabolic process GO:0031324 407 0.657
Human
rna catabolic process GO:0006401 118 0.630
rna splicing via transesterification reactions GO:0000375 118 0.607
heterocycle catabolic process GO:0046700 494 0.603
ribonucleoprotein complex assembly GO:0022618 143 0.596
Human
gene silencing GO:0016458 151 0.544
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.541
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.531
rna splicing GO:0008380 131 0.449
negative regulation of gene expression GO:0010629 312 0.416
Human Fly
cellular nitrogen compound catabolic process GO:0044270 494 0.376
regulation of molecular function GO:0065009 320 0.368
Human
single organism cellular localization GO:1902580 375 0.358
translation GO:0006412 230 0.337
positive regulation of translation GO:0045727 34 0.333
Human
mrna processing GO:0006397 185 0.333
metal ion transport GO:0030001 75 0.288
organic cyclic compound catabolic process GO:1901361 499 0.288
translational initiation GO:0006413 56 0.269
negative regulation of intracellular signal transduction GO:1902532 27 0.258
Human
mitochondrion organization GO:0007005 261 0.242
positive regulation of gene expression GO:0010628 321 0.240
Human
cation transport GO:0006812 166 0.234
snorna metabolic process GO:0016074 40 0.226
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 15 0.222
ion transport GO:0006811 274 0.215
response to abiotic stimulus GO:0009628 159 0.211
Human
aromatic compound catabolic process GO:0019439 491 0.207
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.200
Human
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.189
ribonucleoprotein complex subunit organization GO:0071826 152 0.188
transition metal ion transport GO:0000041 45 0.186
negative regulation of macromolecule metabolic process GO:0010605 375 0.184
Human Fly
ribosome assembly GO:0042255 57 0.181
Human
mitotic cell cycle GO:0000278 306 0.167
Human Fly
establishment of protein localization GO:0045184 367 0.163
nucleobase containing compound catabolic process GO:0034655 479 0.162
regulation of biological quality GO:0065008 391 0.156
anion transport GO:0006820 145 0.151
regulation of cell cycle GO:0051726 195 0.146
Human Worm
organelle assembly GO:0070925 118 0.140
Human
negative regulation of rna biosynthetic process GO:1902679 260 0.139
chromatin organization GO:0006325 242 0.138
purine ribonucleoside metabolic process GO:0046128 380 0.136
inorganic ion transmembrane transport GO:0098660 109 0.135
rna surveillance GO:0071025 30 0.131
positive regulation of rna metabolic process GO:0051254 294 0.127
Human
regulation of cellular protein metabolic process GO:0032268 232 0.122
Human
carbohydrate derivative metabolic process GO:1901135 549 0.120
nitrogen compound transport GO:0071705 212 0.117
ribosome biogenesis GO:0042254 335 0.115
Human
positive regulation of macromolecule metabolic process GO:0010604 394 0.113
Human
aerobic respiration GO:0009060 55 0.112
cellular response to starvation GO:0009267 90 0.105
mitotic cell cycle phase transition GO:0044772 141 0.105
Human
regulation of translation GO:0006417 89 0.104
Human
ion transmembrane transport GO:0034220 200 0.101
sulfur compound metabolic process GO:0006790 95 0.100
positive regulation of rna biosynthetic process GO:1902680 286 0.098
Human
modification dependent macromolecule catabolic process GO:0043632 203 0.098
macromolecule catabolic process GO:0009057 383 0.097
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.097
Human
positive regulation of transcription dna templated GO:0045893 286 0.096
Human
purine ribonucleoside catabolic process GO:0046130 330 0.094
rna localization GO:0006403 112 0.094
negative regulation of gene expression epigenetic GO:0045814 147 0.092
stress granule assembly GO:0034063 8 0.092
Human
regulation of gene expression epigenetic GO:0040029 147 0.092
Fly
negative regulation of transcription dna templated GO:0045892 258 0.092
negative regulation of cellular component organization GO:0051129 109 0.091
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.091
response to extracellular stimulus GO:0009991 156 0.089
regulation of catabolic process GO:0009894 199 0.089
spliceosomal complex assembly GO:0000245 21 0.089
negative regulation of protein metabolic process GO:0051248 85 0.087
Human
cellular respiration GO:0045333 82 0.085
chromatin silencing GO:0006342 147 0.085
nucleobase containing small molecule metabolic process GO:0055086 491 0.084
protein ubiquitination GO:0016567 118 0.083
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.083
Human
posttranscriptional regulation of gene expression GO:0010608 115 0.081
Human Fly
golgi vesicle transport GO:0048193 188 0.081
response to starvation GO:0042594 96 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.080
Human
response to heat GO:0009408 69 0.080
polyadenylation dependent rna catabolic process GO:0043633 22 0.079
energy derivation by oxidation of organic compounds GO:0015980 125 0.078
chromatin modification GO:0016568 200 0.078
response to nutrient levels GO:0031667 150 0.077
regulation of translational initiation GO:0006446 18 0.076
Human
positive regulation of protein metabolic process GO:0051247 93 0.075
Human
negative regulation of cellular protein metabolic process GO:0032269 85 0.075
Human
positive regulation of biosynthetic process GO:0009891 336 0.075
Human
telomere organization GO:0032200 75 0.075
endonucleolytic cleavage involved in rrna processing GO:0000478 47 0.074
carbohydrate derivative biosynthetic process GO:1901137 181 0.074
cellular cation homeostasis GO:0030003 100 0.074
negative regulation of rna metabolic process GO:0051253 262 0.073
ribosomal small subunit biogenesis GO:0042274 124 0.072
establishment of protein localization to organelle GO:0072594 278 0.071
regulation of catalytic activity GO:0050790 307 0.070
Human
intracellular signal transduction GO:0035556 112 0.070
Human
regulation of mrna splicing via spliceosome GO:0048024 3 0.067
regulation of intracellular signal transduction GO:1902531 78 0.066
Human
organic anion transport GO:0015711 114 0.065
anatomical structure development GO:0048856 160 0.061
Worm Fly
organophosphate catabolic process GO:0046434 338 0.061
mitotic cell cycle checkpoint GO:0007093 56 0.058
intracellular protein transport GO:0006886 319 0.057
positive regulation of nucleic acid templated transcription GO:1903508 286 0.057
Human
homeostatic process GO:0042592 227 0.057
protein complex biogenesis GO:0070271 314 0.056
Human
nucleoside metabolic process GO:0009116 394 0.056
cofactor metabolic process GO:0051186 126 0.055
coenzyme metabolic process GO:0006732 104 0.055
dna damage checkpoint GO:0000077 29 0.054
purine containing compound catabolic process GO:0072523 332 0.054
ncrna catabolic process GO:0034661 33 0.054
positive regulation of mrna processing GO:0050685 3 0.054
cellular metal ion homeostasis GO:0006875 78 0.053
cellular response to extracellular stimulus GO:0031668 150 0.053
localization within membrane GO:0051668 29 0.050
negative regulation of biosynthetic process GO:0009890 312 0.050
Human
regulation of mitotic cell cycle GO:0007346 107 0.050
Human
ribonucleoprotein complex export from nucleus GO:0071426 46 0.050
regulation of protein metabolic process GO:0051246 237 0.049
Human
carboxylic acid transport GO:0046942 74 0.048
rrna processing GO:0006364 227 0.047
oxidation reduction process GO:0055114 353 0.047
carbohydrate derivative catabolic process GO:1901136 339 0.046
glycosyl compound metabolic process GO:1901657 398 0.046
regulation of filamentous growth GO:0010570 38 0.045
cellular transition metal ion homeostasis GO:0046916 59 0.045
gene silencing by rna GO:0031047 3 0.044
Fly
rna 3 end processing GO:0031123 88 0.044
ncrna processing GO:0034470 330 0.044
nuclear transport GO:0051169 165 0.044
ascospore formation GO:0030437 107 0.043
phosphatidylcholine metabolic process GO:0046470 20 0.043
organelle localization GO:0051640 128 0.042
anatomical structure morphogenesis GO:0009653 160 0.041
Fly
purine nucleoside metabolic process GO:0042278 380 0.041
dna repair GO:0006281 236 0.041
cell growth GO:0016049 89 0.041
Human
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 46 0.040
nuclear export GO:0051168 124 0.040
single organism membrane organization GO:0044802 275 0.040
negative regulation of molecular function GO:0044092 68 0.040
Human
cellular response to dna damage stimulus GO:0006974 287 0.039
negative regulation of translation GO:0017148 18 0.039
Human
protein localization to membrane GO:0072657 102 0.038
covalent chromatin modification GO:0016569 119 0.037
cellular macromolecule catabolic process GO:0044265 363 0.037
lipid localization GO:0010876 60 0.037
regulation of cellular component organization GO:0051128 334 0.036
Human Worm
generation of precursor metabolites and energy GO:0006091 147 0.036
regulation of chromatin silencing GO:0031935 39 0.036
nuclear mrna surveillance GO:0071028 22 0.036
organonitrogen compound biosynthetic process GO:1901566 314 0.036
growth GO:0040007 157 0.036
Human
golgi to plasma membrane transport GO:0006893 33 0.035
nucleoside catabolic process GO:0009164 335 0.035
negative regulation of chromatin silencing GO:0031936 25 0.035
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 96 0.035
ncrna 3 end processing GO:0043628 44 0.035
nuclear rna surveillance GO:0071027 30 0.034
regulation of phosphatidylcholine biosynthetic process GO:2001245 7 0.034
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.034
cellular divalent inorganic cation homeostasis GO:0072503 21 0.034
regulation of gene silencing GO:0060968 41 0.033
cytoskeleton organization GO:0007010 230 0.033
regulation of protein complex assembly GO:0043254 77 0.033
Human
negative regulation of gene silencing GO:0060969 27 0.033
positive regulation of cell cycle GO:0045787 32 0.031
Human
rrna catabolic process GO:0016075 31 0.031
cell cycle phase transition GO:0044770 144 0.031
Human
positive regulation of cellular protein metabolic process GO:0032270 89 0.031
Human
microtubule cytoskeleton organization GO:0000226 109 0.031
regulation of protein modification process GO:0031399 110 0.031
signal transduction GO:0007165 208 0.031
Human
ribosome localization GO:0033750 46 0.031
coenzyme biosynthetic process GO:0009108 66 0.030
positive regulation of gene expression epigenetic GO:0045815 25 0.030
lipid biosynthetic process GO:0008610 170 0.030
snorna processing GO:0043144 34 0.030
positive regulation of cellular biosynthetic process GO:0031328 336 0.030
Human
sexual sporulation GO:0034293 113 0.030
cation transmembrane transport GO:0098655 135 0.029
alcohol biosynthetic process GO:0046165 75 0.029
dna recombination GO:0006310 172 0.029
regulation of cellular catabolic process GO:0031329 195 0.029
dna replication GO:0006260 147 0.029
organophosphate metabolic process GO:0019637 597 0.029
sporulation GO:0043934 132 0.028
snrna processing GO:0016180 17 0.028
sporulation resulting in formation of a cellular spore GO:0030435 129 0.027
response to external stimulus GO:0009605 158 0.027
Human
positive regulation of cell death GO:0010942 3 0.027
Human Fly
nucleotide catabolic process GO:0009166 330 0.027
developmental process involved in reproduction GO:0003006 159 0.026
Worm Fly
transcription coupled nucleotide excision repair GO:0006283 16 0.026
positive regulation of catabolic process GO:0009896 135 0.026
glycosyl compound catabolic process GO:1901658 335 0.026
cellular homeostasis GO:0019725 138 0.026
telomere maintenance via telomerase GO:0007004 21 0.026
ribonucleoside catabolic process GO:0042454 332 0.026
phosphorylation GO:0016310 291 0.026
negative regulation of signal transduction GO:0009968 30 0.026
Human
cellular response to nutrient levels GO:0031669 144 0.025
dna integrity checkpoint GO:0031570 41 0.025
regulation of cellular component biogenesis GO:0044087 112 0.025
Human
mrna splice site selection GO:0006376 8 0.025
negative regulation of response to stimulus GO:0048585 40 0.025
Human
developmental process GO:0032502 261 0.025
Worm Fly
hydrogen transport GO:0006818 61 0.025
mitotic cell cycle process GO:1903047 294 0.025
Human Fly
regulation of cell cycle process GO:0010564 150 0.025
Human Worm
regulation of vesicle mediated transport GO:0060627 39 0.025
nucleotide metabolic process GO:0009117 453 0.025
cation homeostasis GO:0055080 105 0.024
termination of rna polymerase ii transcription poly a coupled GO:0030846 10 0.024
ribonucleotide metabolic process GO:0009259 377 0.024
protein complex disassembly GO:0043241 70 0.024
regulation of kinase activity GO:0043549 71 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.024
lipid metabolic process GO:0006629 269 0.024
mrna 3 end processing GO:0031124 54 0.024
organic acid transport GO:0015849 77 0.023
positive regulation of intracellular protein transport GO:0090316 3 0.023
regulation of rna splicing GO:0043484 3 0.023
phospholipid transport GO:0015914 23 0.023
transition metal ion homeostasis GO:0055076 59 0.023
purine containing compound metabolic process GO:0072521 400 0.022
purine nucleoside catabolic process GO:0006152 330 0.022
protein phosphorylation GO:0006468 197 0.022
cellular response to external stimulus GO:0071496 150 0.022
vesicle organization GO:0016050 68 0.022
ribonucleoside metabolic process GO:0009119 389 0.022
programmed cell death GO:0012501 30 0.022
Human Fly
ribosomal subunit export from nucleus GO:0000054 46 0.022
regulation of mitotic cell cycle phase transition GO:1901990 68 0.021
Human
positive regulation of cellular component organization GO:0051130 116 0.021
divalent inorganic cation homeostasis GO:0072507 21 0.021
positive regulation of mrna metabolic process GO:1903313 7 0.021
positive regulation of mitotic cell cycle GO:0045931 16 0.021
Human
regulation of mrna metabolic process GO:1903311 17 0.021
regulation of cell growth GO:0001558 29 0.021
Human
organonitrogen compound catabolic process GO:1901565 404 0.021
purine nucleoside triphosphate catabolic process GO:0009146 329 0.021
intracellular mrna localization GO:0008298 23 0.021
dna templated transcription termination GO:0006353 42 0.021
fatty acid metabolic process GO:0006631 51 0.021
g1 s transition of mitotic cell cycle GO:0000082 64 0.020
Human
proteolysis GO:0006508 268 0.020
Human
positive regulation of programmed cell death GO:0043068 3 0.020
Human Fly
protein complex assembly GO:0006461 302 0.020
Human
protein modification by small protein conjugation GO:0032446 144 0.020
regulation of dna replication GO:0006275 51 0.020
divalent metal ion transport GO:0070838 17 0.019
post golgi vesicle mediated transport GO:0006892 72 0.019
secretion GO:0046903 50 0.019
regulation of cellular ketone metabolic process GO:0010565 42 0.019
transmembrane transport GO:0055085 349 0.019
snrna 3 end processing GO:0034472 16 0.019
protein transport GO:0015031 345 0.019
microtubule based process GO:0007017 117 0.018
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.018
protein deubiquitination GO:0016579 17 0.018
regulation of cellular amine metabolic process GO:0033238 21 0.018
rrna metabolic process GO:0016072 244 0.018
anatomical structure homeostasis GO:0060249 74 0.018
positive regulation of dna templated transcription elongation GO:0032786 42 0.018
rrna transport GO:0051029 18 0.018
response to chemical GO:0042221 390 0.018
Human Fly
cellular component disassembly GO:0022411 86 0.018
maturation of 5 8s rrna GO:0000460 80 0.018
cytoplasmic translation GO:0002181 65 0.018
cell development GO:0048468 107 0.018
Worm Fly
negative regulation of nucleic acid templated transcription GO:1903507 260 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.017
regulation of organelle organization GO:0033043 243 0.017
Worm
positive regulation of apoptotic process GO:0043065 3 0.017
Human
purine ribonucleotide catabolic process GO:0009154 327 0.017
positive regulation of molecular function GO:0044093 185 0.017
Human
apoptotic process GO:0006915 30 0.017
Human
establishment of ribosome localization GO:0033753 46 0.017
regulation of generation of precursor metabolites and energy GO:0043467 23 0.017
establishment of rna localization GO:0051236 92 0.017
death GO:0016265 30 0.017
Human Fly
regulation of dna dependent dna replication GO:0090329 37 0.017
maturation of ssu rrna GO:0030490 105 0.017
rna dependent dna replication GO:0006278 25 0.017
purine nucleoside triphosphate metabolic process GO:0009144 356 0.016
regulation of growth GO:0040008 50 0.016
Human
filamentous growth of a population of unicellular organisms GO:0044182 109 0.016
fatty acid transport GO:0015908 8 0.016
negative regulation of cell cycle process GO:0010948 86 0.016
negative regulation of catalytic activity GO:0043086 60 0.016
Human
regulation of dna metabolic process GO:0051052 100 0.016
small molecule biosynthetic process GO:0044283 258 0.016
amine metabolic process GO:0009308 51 0.016
mitotic dna damage checkpoint GO:0044773 11 0.016
regulation of response to stress GO:0080134 57 0.016
pseudohyphal growth GO:0007124 75 0.016
membrane organization GO:0061024 276 0.015
macromolecular complex disassembly GO:0032984 80 0.015
telomere maintenance via telomere lengthening GO:0010833 22 0.015
nuclear division GO:0000280 263 0.015
Worm Fly
alcohol metabolic process GO:0006066 112 0.015
ribonucleoside biosynthetic process GO:0042455 37 0.015
regulation of phosphorylation GO:0042325 86 0.015
metal ion homeostasis GO:0055065 79 0.014
negative regulation of translational initiation GO:0045947 4 0.014
maintenance of location GO:0051235 66 0.014
reproductive process in single celled organism GO:0022413 145 0.014
cellular carbohydrate metabolic process GO:0044262 135 0.014
cellular response to hypoxia GO:0071456 4 0.014
positive regulation of cellular catabolic process GO:0031331 128 0.014
ribonucleoprotein complex localization GO:0071166 46 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.014
carboxylic acid biosynthetic process GO:0046394 152 0.014
negative regulation of phosphorus metabolic process GO:0010563 49 0.014
protein modification by small protein conjugation or removal GO:0070647 172 0.014
response to temperature stimulus GO:0009266 74 0.014
termination of rna polymerase ii transcription GO:0006369 26 0.014
nucleic acid transport GO:0050657 94 0.014
single organism catabolic process GO:0044712 619 0.014
regulation of dna templated transcription elongation GO:0032784 44 0.014
negative regulation of growth GO:0045926 13 0.014
Human
ribosomal large subunit biogenesis GO:0042273 98 0.014
protein modification by small protein removal GO:0070646 29 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.013
rna transport GO:0050658 92 0.013
tor signaling GO:0031929 17 0.013
regulation of cell division GO:0051302 113 0.013
Worm
regulation of cell cycle phase transition GO:1901987 70 0.013
Human
nucleoside triphosphate catabolic process GO:0009143 329 0.013
cut metabolic process GO:0071043 12 0.013
cellular chemical homeostasis GO:0055082 123 0.013
regulation of cellular localization GO:0060341 50 0.013
cellular response to chemical stimulus GO:0070887 315 0.013
Human
protein localization to plasma membrane GO:0072659 18 0.013
cellular ion homeostasis GO:0006873 112 0.013
glycosyl compound biosynthetic process GO:1901659 42 0.013
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.013
response to osmotic stress GO:0006970 83 0.012
Human
positive regulation of hydrolase activity GO:0051345 112 0.012
Human
protein localization to organelle GO:0033365 337 0.012
negative regulation of phosphate metabolic process GO:0045936 49 0.012
negative regulation of cellular catabolic process GO:0031330 43 0.012
cellular response to osmotic stress GO:0071470 50 0.012
Human
regulation of response to dna damage stimulus GO:2001020 17 0.012
cell cycle g1 s phase transition GO:0044843 64 0.012
Human
trna modification GO:0006400 75 0.012
amide transport GO:0042886 22 0.012
negative regulation of mitotic cell cycle GO:0045930 63 0.012
ribose phosphate metabolic process GO:0019693 384 0.012
multi organism process GO:0051704 233 0.012
Human Worm Fly
regulation of phosphorus metabolic process GO:0051174 230 0.012
regulation of transferase activity GO:0051338 83 0.012
mitotic spindle organization GO:0007052 30 0.012
negative regulation of cell cycle phase transition GO:1901988 59 0.012
histone methylation GO:0016571 28 0.012
ribosomal small subunit export from nucleus GO:0000056 13 0.012
response to acid chemical GO:0001101 19 0.012
cell communication GO:0007154 345 0.011
Human
positive regulation of growth GO:0045927 19 0.011
Human
cellular response to oxidative stress GO:0034599 94 0.011
cofactor biosynthetic process GO:0051188 80 0.011
nucleoside triphosphate metabolic process GO:0009141 364 0.011
endoplasmic reticulum organization GO:0007029 30 0.011
telomere maintenance GO:0000723 74 0.011
pyruvate metabolic process GO:0006090 37 0.011
cell wall organization GO:0071555 146 0.011
regulation of autophagy GO:0010506 18 0.011
regulation of phosphate metabolic process GO:0019220 230 0.011
nucleoside monophosphate metabolic process GO:0009123 267 0.011
single organism developmental process GO:0044767 258 0.011
Worm Fly
protein targeting GO:0006605 272 0.011
purine nucleotide catabolic process GO:0006195 328 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.011
atp catabolic process GO:0006200 224 0.011
negative regulation of protein complex disassembly GO:0043242 14 0.011
response to organic cyclic compound GO:0014070 1 0.010
Fly
organic acid metabolic process GO:0006082 352 0.010
glycerolipid metabolic process GO:0046486 108 0.010
ribonucleotide catabolic process GO:0009261 327 0.010
thioester metabolic process GO:0035383 13 0.010
negative regulation of pseudohyphal growth GO:2000221 8 0.010
nucleoside phosphate catabolic process GO:1901292 331 0.010
ribonucleoside monophosphate metabolic process GO:0009161 265 0.010
positive regulation of cytoplasmic transport GO:1903651 4 0.010
cytoplasmic translational initiation GO:0002183 7 0.010

DED1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
congenital hypoplastic anemia DOID:1342 0 0.032
immune system disease DOID:2914 0 0.032
anemia DOID:2355 0 0.032
aplastic anemia DOID:12449 0 0.032
bone marrow disease DOID:4961 0 0.032
hematopoietic system disease DOID:74 0 0.032
diamond blackfan anemia DOID:1339 0 0.027