Saccharomyces cerevisiae

70 known processes

UBR1 (YGR184C)

Ubr1p

(Aliases: PTR1)

UBR1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 203 0.925
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.861
ubiquitin dependent protein catabolic process GO:0006511 181 0.848
cellular response to dna damage stimulus GO:0006974 287 0.829
modification dependent protein catabolic process GO:0019941 181 0.788
dna repair GO:0006281 236 0.771
proteasomal protein catabolic process GO:0010498 141 0.767
cellular protein catabolic process GO:0044257 213 0.758
cellular macromolecule catabolic process GO:0044265 363 0.744
protein catabolic process GO:0030163 221 0.683
protein modification by small protein conjugation GO:0032446 144 0.667
macromolecule catabolic process GO:0009057 383 0.618
proteolysis GO:0006508 268 0.613
organic acid metabolic process GO:0006082 352 0.586
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.512
mitotic cell cycle GO:0000278 306 0.461
protein ubiquitination GO:0016567 118 0.451
regulation of proteasomal protein catabolic process GO:0061136 34 0.439
protein polyubiquitination GO:0000209 20 0.378
ribose phosphate metabolic process GO:0019693 384 0.345
single organism cellular localization GO:1902580 375 0.317
negative regulation of cellular metabolic process GO:0031324 407 0.297
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.284
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.273
chromatin modification GO:0016568 200 0.270
single organism catabolic process GO:0044712 619 0.247
regulation of molecular function GO:0065009 320 0.247
regulation of protein catabolic process GO:0042176 40 0.234
nuclear division GO:0000280 263 0.228
carboxylic acid metabolic process GO:0019752 338 0.219
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.217
regulation of cell cycle GO:0051726 195 0.211
regulation of proteolysis GO:0030162 44 0.192
cellular nitrogen compound catabolic process GO:0044270 494 0.177
negative regulation of gene expression GO:0010629 312 0.163
regulation of cellular catabolic process GO:0031329 195 0.156
glycosyl compound metabolic process GO:1901657 398 0.156
regulation of cellular protein metabolic process GO:0032268 232 0.155
regulation of chromosome organization GO:0033044 66 0.153
regulation of cell division GO:0051302 113 0.153
er associated ubiquitin dependent protein catabolic process GO:0030433 46 0.152
ribonucleoside metabolic process GO:0009119 389 0.152
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.150
atp metabolic process GO:0046034 251 0.145
heterocycle catabolic process GO:0046700 494 0.144
purine containing compound metabolic process GO:0072521 400 0.142
regulation of catabolic process GO:0009894 199 0.140
purine nucleoside monophosphate metabolic process GO:0009126 262 0.127
regulation of protein metabolic process GO:0051246 237 0.124
negative regulation of biosynthetic process GO:0009890 312 0.124
negative regulation of organelle organization GO:0010639 103 0.124
organelle fission GO:0048285 272 0.123
histone modification GO:0016570 119 0.122
regulation of cellular component organization GO:0051128 334 0.120
regulation of mitosis GO:0007088 65 0.120
negative regulation of cellular biosynthetic process GO:0031327 312 0.119
regulation of biological quality GO:0065008 391 0.118
regulation of cellular protein catabolic process GO:1903362 36 0.116
purine ribonucleotide metabolic process GO:0009150 372 0.114
covalent chromatin modification GO:0016569 119 0.106
regulation of nuclear division GO:0051783 103 0.104
mitotic nuclear division GO:0007067 131 0.102
ribonucleotide catabolic process GO:0009261 327 0.102
nucleoside catabolic process GO:0009164 335 0.100
small gtpase mediated signal transduction GO:0007264 36 0.099
organophosphate catabolic process GO:0046434 338 0.093
meiotic cell cycle GO:0051321 272 0.092
negative regulation of chromosome organization GO:2001251 39 0.092
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.090
regulation of cell cycle process GO:0010564 150 0.089
chromatin organization GO:0006325 242 0.089
double strand break repair GO:0006302 105 0.089
negative regulation of rna metabolic process GO:0051253 262 0.088
purine nucleotide metabolic process GO:0006163 376 0.088
cellular ketone metabolic process GO:0042180 63 0.087
cellular amino acid metabolic process GO:0006520 225 0.086
protein complex biogenesis GO:0070271 314 0.085
protein modification by small protein conjugation or removal GO:0070647 172 0.084
nucleoside phosphate catabolic process GO:1901292 331 0.084
nucleoside monophosphate metabolic process GO:0009123 267 0.082
protein transport GO:0015031 345 0.081
purine nucleoside metabolic process GO:0042278 380 0.081
regulation of dna templated transcription in response to stress GO:0043620 51 0.076
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.076
regulation of organelle organization GO:0033043 243 0.076
regulation of hydrolase activity GO:0051336 133 0.072
carbohydrate derivative metabolic process GO:1901135 549 0.072
organic cyclic compound catabolic process GO:1901361 499 0.072
cell division GO:0051301 205 0.070
cellular component disassembly GO:0022411 86 0.070
nucleoside triphosphate metabolic process GO:0009141 364 0.069
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.069
aromatic compound catabolic process GO:0019439 491 0.069
response to abiotic stimulus GO:0009628 159 0.069
nucleoside triphosphate catabolic process GO:0009143 329 0.066
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 26 0.066
response to external stimulus GO:0009605 158 0.063
organelle localization GO:0051640 128 0.063
mitotic sister chromatid segregation GO:0000070 85 0.061
homeostatic process GO:0042592 227 0.061
purine ribonucleotide catabolic process GO:0009154 327 0.061
cellular protein complex assembly GO:0043623 209 0.061
response to temperature stimulus GO:0009266 74 0.059
positive regulation of phosphorus metabolic process GO:0010562 147 0.059
ribonucleoside triphosphate catabolic process GO:0009203 327 0.058
chromatin remodeling GO:0006338 80 0.058
positive regulation of cellular catabolic process GO:0031331 128 0.056
protein monoubiquitination GO:0006513 13 0.055
Yeast
cell communication GO:0007154 345 0.055
chromatin silencing GO:0006342 147 0.055
positive regulation of phosphate metabolic process GO:0045937 147 0.054
positive regulation of catalytic activity GO:0043085 178 0.054
oxidation reduction process GO:0055114 353 0.054
organonitrogen compound catabolic process GO:1901565 404 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.053
single organism developmental process GO:0044767 258 0.052
regulation of protein ubiquitination GO:0031396 20 0.051
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.050
positive regulation of molecular function GO:0044093 185 0.050
rrna metabolic process GO:0016072 244 0.049
negative regulation of macromolecule metabolic process GO:0010605 375 0.048
signal transduction GO:0007165 208 0.048
oxoacid metabolic process GO:0043436 351 0.048
nucleotide metabolic process GO:0009117 453 0.048
regulation of intracellular signal transduction GO:1902531 78 0.048
regulation of chromatin modification GO:1903308 23 0.048
purine nucleoside monophosphate catabolic process GO:0009128 224 0.047
cellular response to chemical stimulus GO:0070887 315 0.046
regulation of histone modification GO:0031056 18 0.045
nucleoside monophosphate catabolic process GO:0009125 224 0.044
purine nucleotide catabolic process GO:0006195 328 0.044
cellular homeostasis GO:0019725 138 0.044
negative regulation of rna biosynthetic process GO:1902679 260 0.044
atp catabolic process GO:0006200 224 0.043
ribonucleoside catabolic process GO:0042454 332 0.043
purine nucleoside triphosphate catabolic process GO:0009146 329 0.042
signaling GO:0023052 208 0.042
positive regulation of catabolic process GO:0009896 135 0.042
mitotic cell cycle phase transition GO:0044772 141 0.042
nucleoside metabolic process GO:0009116 394 0.042
purine nucleoside triphosphate metabolic process GO:0009144 356 0.041
response to nutrient levels GO:0031667 150 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.040
negative regulation of cellular protein metabolic process GO:0032269 85 0.040
negative regulation of nucleic acid templated transcription GO:1903507 260 0.040
cellular response to nutrient GO:0031670 50 0.039
purine nucleoside catabolic process GO:0006152 330 0.039
dna conformation change GO:0071103 98 0.037
regulation of catalytic activity GO:0050790 307 0.037
cell cycle phase transition GO:0044770 144 0.037
amide transport GO:0042886 22 0.037
negative regulation of gene expression epigenetic GO:0045814 147 0.037
regulation of phosphate metabolic process GO:0019220 230 0.037
mitotic cell cycle process GO:1903047 294 0.035
negative regulation of cellular component organization GO:0051129 109 0.034
purine ribonucleoside metabolic process GO:0046128 380 0.034
regulation of signal transduction GO:0009966 114 0.034
mrna metabolic process GO:0016071 269 0.033
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.033
dna templated transcription elongation GO:0006354 91 0.032
nuclear transport GO:0051169 165 0.032
negative regulation of response to stimulus GO:0048585 40 0.032
regulation of localization GO:0032879 127 0.032
monocarboxylic acid metabolic process GO:0032787 122 0.031
negative regulation of transcription dna templated GO:0045892 258 0.031
nucleobase containing compound catabolic process GO:0034655 479 0.031
establishment of organelle localization GO:0051656 96 0.031
organophosphate metabolic process GO:0019637 597 0.031
positive regulation of macromolecule metabolic process GO:0010604 394 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.030
chromosome segregation GO:0007059 159 0.030
cell cycle g1 s phase transition GO:0044843 64 0.030
nucleocytoplasmic transport GO:0006913 163 0.030
response to nutrient GO:0007584 52 0.030
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.030
response to chemical GO:0042221 390 0.030
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.029
cellular response to extracellular stimulus GO:0031668 150 0.029
ribonucleoside triphosphate metabolic process GO:0009199 356 0.029
nucleotide catabolic process GO:0009166 330 0.029
regulation of phosphorus metabolic process GO:0051174 230 0.027
posttranscriptional regulation of gene expression GO:0010608 115 0.027
protein complex assembly GO:0006461 302 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.027
protein processing GO:0016485 64 0.027
establishment of protein localization to organelle GO:0072594 278 0.027
multi organism reproductive process GO:0044703 216 0.027
meiotic nuclear division GO:0007126 163 0.027
positive regulation of rna metabolic process GO:0051254 294 0.026
protein complex disassembly GO:0043241 70 0.026
ribosome biogenesis GO:0042254 335 0.026
carbohydrate derivative catabolic process GO:1901136 339 0.026
nucleoside phosphate metabolic process GO:0006753 458 0.026
negative regulation of mitotic cell cycle GO:0045930 63 0.026
generation of precursor metabolites and energy GO:0006091 147 0.026
purine ribonucleoside catabolic process GO:0046130 330 0.025
reproductive process in single celled organism GO:0022413 145 0.025
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.024
peptidyl lysine modification GO:0018205 77 0.024
regulation of mitotic cell cycle phase transition GO:1901990 68 0.024
negative regulation of protein metabolic process GO:0051248 85 0.023
ribonucleoside monophosphate catabolic process GO:0009158 224 0.023
nucleobase containing small molecule metabolic process GO:0055086 491 0.023
cellular response to nutrient levels GO:0031669 144 0.023
nuclear export GO:0051168 124 0.023
negative regulation of protein maturation GO:1903318 33 0.023
protein localization to organelle GO:0033365 337 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.022
regulation of mitotic cell cycle GO:0007346 107 0.022
nitrogen compound transport GO:0071705 212 0.022
regulation of protein maturation GO:1903317 34 0.022
cellular response to topologically incorrect protein GO:0035967 32 0.021
anatomical structure formation involved in morphogenesis GO:0048646 136 0.021
single organism signaling GO:0044700 208 0.021
peptidyl amino acid modification GO:0018193 116 0.021
purine containing compound catabolic process GO:0072523 332 0.021
regulation of transferase activity GO:0051338 83 0.021
positive regulation of protein metabolic process GO:0051247 93 0.020
positive regulation of gene expression GO:0010628 321 0.020
regulation of cell cycle phase transition GO:1901987 70 0.020
ribonucleoside monophosphate metabolic process GO:0009161 265 0.020
carbon catabolite regulation of transcription GO:0045990 39 0.020
positive regulation of rna biosynthetic process GO:1902680 286 0.020
regulation of fatty acid oxidation GO:0046320 3 0.020
macromolecular complex disassembly GO:0032984 80 0.020
response to extracellular stimulus GO:0009991 156 0.020
positive regulation of cellular biosynthetic process GO:0031328 336 0.019
phosphorylation GO:0016310 291 0.019
regulation of kinase activity GO:0043549 71 0.019
sister chromatid segregation GO:0000819 93 0.019
anatomical structure development GO:0048856 160 0.019
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.018
lipid metabolic process GO:0006629 269 0.018
ribonucleotide metabolic process GO:0009259 377 0.018
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.018
response to hypoxia GO:0001666 4 0.017
dna packaging GO:0006323 55 0.017
regulation of response to stimulus GO:0048583 157 0.017
negative regulation of cell communication GO:0010648 33 0.017
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.016
positive regulation of cellular protein metabolic process GO:0032270 89 0.016
dna geometric change GO:0032392 43 0.016
negative regulation of cell division GO:0051782 66 0.015
spindle checkpoint GO:0031577 35 0.015
chromatin silencing at telomere GO:0006348 84 0.015
small molecule biosynthetic process GO:0044283 258 0.015
cell differentiation GO:0030154 161 0.015
positive regulation of transferase activity GO:0051347 28 0.015
response to organic substance GO:0010033 182 0.015
glycosyl compound catabolic process GO:1901658 335 0.015
lipid localization GO:0010876 60 0.014
cellular response to heat GO:0034605 53 0.014
ion transport GO:0006811 274 0.014
response to heat GO:0009408 69 0.014
single organism membrane organization GO:0044802 275 0.014
negative regulation of protein processing GO:0010955 33 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.014
sister chromatid cohesion GO:0007062 49 0.014
negative regulation of cell cycle process GO:0010948 86 0.014
ascospore formation GO:0030437 107 0.013
maintenance of location GO:0051235 66 0.013
organelle assembly GO:0070925 118 0.013
regulation of protein kinase activity GO:0045859 67 0.013
rna localization GO:0006403 112 0.013
regulation of purine nucleotide catabolic process GO:0033121 106 0.013
regulation of cellular ketone metabolic process GO:0010565 42 0.013
cellular amine metabolic process GO:0044106 51 0.013
peptidyl lysine acetylation GO:0018394 52 0.013
positive regulation of protein modification process GO:0031401 49 0.012
regulation of response to drug GO:2001023 3 0.012
histone ubiquitination GO:0016574 17 0.012
negative regulation of signal transduction GO:0009968 30 0.012
amine metabolic process GO:0009308 51 0.012
positive regulation of signaling GO:0023056 20 0.012
response to topologically incorrect protein GO:0035966 38 0.012
regulation of lipid metabolic process GO:0019216 45 0.012
protein localization to membrane GO:0072657 102 0.012
energy derivation by oxidation of organic compounds GO:0015980 125 0.012
negative regulation of cell cycle phase transition GO:1901988 59 0.012
transmembrane transport GO:0055085 349 0.012
carbohydrate biosynthetic process GO:0016051 82 0.012
cellular amide metabolic process GO:0043603 59 0.011
mitotic spindle checkpoint GO:0071174 34 0.011
regulation of mitotic sister chromatid separation GO:0010965 29 0.011
positive regulation of response to stimulus GO:0048584 37 0.011
spindle assembly checkpoint GO:0071173 23 0.011
organic acid biosynthetic process GO:0016053 152 0.011
negative regulation of cellular catabolic process GO:0031330 43 0.011
meiotic chromosome segregation GO:0045132 31 0.011
regulation of cellular amino acid metabolic process GO:0006521 16 0.011
organic acid catabolic process GO:0016054 71 0.011
dna recombination GO:0006310 172 0.011
regulation of signaling GO:0023051 119 0.011
gene silencing GO:0016458 151 0.010
carbohydrate derivative biosynthetic process GO:1901137 181 0.010
regulation of nucleotide metabolic process GO:0006140 110 0.010
regulation of protein modification process GO:0031399 110 0.010
regulation of cellular amine metabolic process GO:0033238 21 0.010
anion transport GO:0006820 145 0.010
positive regulation of nucleotide metabolic process GO:0045981 101 0.010
negative regulation of dna metabolic process GO:0051053 36 0.010
dna dependent dna replication GO:0006261 115 0.010
ribosomal small subunit biogenesis GO:0042274 124 0.010

UBR1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010