Saccharomyces cerevisiae

114 known processes

SMC4 (YLR086W)

Smc4p

SMC4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic sister chromatid segregation GO:0000070 85 0.998
sister chromatid segregation GO:0000819 93 0.997
chromosome segregation GO:0007059 159 0.994
chromosome condensation GO:0030261 19 0.991
chromosome separation GO:0051304 33 0.974
mitotic chromosome condensation GO:0007076 11 0.971
dna conformation change GO:0071103 98 0.910
trna gene clustering GO:0070058 7 0.896
mitotic cell cycle process GO:1903047 294 0.871
mitotic cell cycle GO:0000278 306 0.870
mitotic nuclear division GO:0007067 131 0.777
metaphase anaphase transition of cell cycle GO:0044784 28 0.756
regulation of mitotic sister chromatid separation GO:0010965 29 0.751
nuclear division GO:0000280 263 0.740
organelle fission GO:0048285 272 0.716
negative regulation of cell cycle GO:0045786 91 0.709
negative regulation of cell cycle process GO:0010948 86 0.702
rdna condensation GO:0070550 9 0.681
regulation of metaphase anaphase transition of cell cycle GO:1902099 27 0.669
mitotic sister chromatid separation GO:0051306 26 0.668
dna packaging GO:0006323 55 0.627
regulation of mitotic sister chromatid segregation GO:0033047 30 0.597
single organism cellular localization GO:1902580 375 0.567
regulation of mitotic metaphase anaphase transition GO:0030071 27 0.557
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 23 0.536
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.522
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.511
mitotic spindle assembly checkpoint GO:0007094 23 0.507
dna unwinding involved in dna replication GO:0006268 13 0.472
synapsis GO:0007129 19 0.466
negative regulation of mitotic metaphase anaphase transition GO:0045841 23 0.409
negative regulation of macromolecule metabolic process GO:0010605 375 0.402
negative regulation of mitotic sister chromatid separation GO:2000816 23 0.391
negative regulation of mitotic sister chromatid segregation GO:0033048 24 0.366
mitotic sister chromatid cohesion GO:0007064 38 0.343
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.306
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.301
chromosome organization involved in meiosis GO:0070192 32 0.279
negative regulation of biosynthetic process GO:0009890 312 0.273
meiosis i GO:0007127 92 0.270
regulation of cellular component organization GO:0051128 334 0.268
regulation of organelle organization GO:0033043 243 0.251
negative regulation of cellular metabolic process GO:0031324 407 0.240
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.236
dna dependent dna replication GO:0006261 115 0.227
cell division GO:0051301 205 0.227
negative regulation of transcription dna templated GO:0045892 258 0.222
negative regulation of nuclear division GO:0051784 62 0.214
synaptonemal complex assembly GO:0007130 12 0.207
regulation of cell division GO:0051302 113 0.191
regulation of cell cycle process GO:0010564 150 0.188
regulation of cell cycle GO:0051726 195 0.183
regulation of nuclear division GO:0051783 103 0.182
negative regulation of cellular component organization GO:0051129 109 0.182
cellular macromolecule catabolic process GO:0044265 363 0.174
regulation of sister chromatid segregation GO:0033045 30 0.174
meiotic chromosome segregation GO:0045132 31 0.173
mitotic cell cycle checkpoint GO:0007093 56 0.170
regulation of cell cycle phase transition GO:1901987 70 0.170
negative regulation of gene expression GO:0010629 312 0.169
protein localization to organelle GO:0033365 337 0.168
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.168
negative regulation of chromosome segregation GO:0051985 25 0.161
negative regulation of rna metabolic process GO:0051253 262 0.161
regulation of chromosome segregation GO:0051983 44 0.159
negative regulation of nucleic acid templated transcription GO:1903507 260 0.158
double strand break repair GO:0006302 105 0.146
regulation of mitotic cell cycle phase transition GO:1901990 68 0.139
negative regulation of mitotic cell cycle GO:0045930 63 0.130
dna replication GO:0006260 147 0.128
cell cycle phase transition GO:0044770 144 0.125
regulation of meiosis GO:0040020 42 0.124
dna duplex unwinding GO:0032508 42 0.115
macromolecule catabolic process GO:0009057 383 0.111
regulation of catabolic process GO:0009894 199 0.110
negative regulation of cellular biosynthetic process GO:0031327 312 0.108
negative regulation of cell cycle phase transition GO:1901988 59 0.105
gene silencing GO:0016458 151 0.104
meiotic cell cycle GO:0051321 272 0.100
proteasomal protein catabolic process GO:0010498 141 0.095
negative regulation of rna biosynthetic process GO:1902679 260 0.094
mitotic metaphase plate congression GO:0007080 8 0.094
dna geometric change GO:0032392 43 0.093
synaptonemal complex organization GO:0070193 16 0.093
negative regulation of gene expression epigenetic GO:0045814 147 0.092
regulation of mitotic cell cycle GO:0007346 107 0.092
meiotic dna double strand break formation GO:0042138 12 0.091
regulation of meiotic cell cycle GO:0051445 43 0.083
establishment of protein localization GO:0045184 367 0.083
sister chromatid cohesion GO:0007062 49 0.082
negative regulation of sister chromatid segregation GO:0033046 24 0.081
negative regulation of meiosis GO:0045835 23 0.079
homeostatic process GO:0042592 227 0.078
regulation of chromosome organization GO:0033044 66 0.076
negative regulation of cell division GO:0051782 66 0.075
meiotic nuclear division GO:0007126 163 0.073
microtubule cytoskeleton organization GO:0000226 109 0.069
cell cycle checkpoint GO:0000075 82 0.068
negative regulation of meiotic cell cycle GO:0051447 24 0.067
dna repair GO:0006281 236 0.064
telomere maintenance GO:0000723 74 0.064
chromatin silencing GO:0006342 147 0.064
protein transport GO:0015031 345 0.061
cellular nitrogen compound catabolic process GO:0044270 494 0.060
peptidyl amino acid modification GO:0018193 116 0.058
single organism catabolic process GO:0044712 619 0.058
negative regulation of organelle organization GO:0010639 103 0.058
telomere maintenance via recombination GO:0000722 32 0.057
sister chromatid biorientation GO:0031134 8 0.057
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.056
regulation of protein catabolic process GO:0042176 40 0.052
regulation of gene expression epigenetic GO:0040029 147 0.052
cellular protein catabolic process GO:0044257 213 0.051
protein processing GO:0016485 64 0.050
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 35 0.050
microtubule cytoskeleton organization involved in mitosis GO:1902850 13 0.050
protein targeting GO:0006605 272 0.049
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.048
protein maturation GO:0051604 76 0.048
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.047
cytoskeleton organization GO:0007010 230 0.047
regulation of meiosis i GO:0060631 14 0.047
negative regulation of chromosome organization GO:2001251 39 0.046
negative regulation of cellular protein catabolic process GO:1903363 27 0.042
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 24 0.042
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.040
aromatic compound catabolic process GO:0019439 491 0.039
response to chemical GO:0042221 390 0.039
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.039
regulation of biological quality GO:0065008 391 0.038
spindle assembly checkpoint GO:0071173 23 0.038
positive regulation of chromosome segregation GO:0051984 15 0.038
establishment of protein localization to organelle GO:0072594 278 0.037
anatomical structure homeostasis GO:0060249 74 0.035
regulation of cellular protein metabolic process GO:0032268 232 0.034
nuclear transport GO:0051169 165 0.033
response to external stimulus GO:0009605 158 0.033
regulation of mitosis GO:0007088 65 0.032
mitotic cell cycle phase transition GO:0044772 141 0.031
establishment of mitotic sister chromatid cohesion GO:0034087 15 0.031
protein catabolic process GO:0030163 221 0.030
intracellular protein transport GO:0006886 319 0.030
modification dependent macromolecule catabolic process GO:0043632 203 0.030
cellular response to external stimulus GO:0071496 150 0.029
proteolysis GO:0006508 268 0.029
negative regulation of protein metabolic process GO:0051248 85 0.029
cellular amino acid metabolic process GO:0006520 225 0.028
cellular response to chemical stimulus GO:0070887 315 0.028
single organism carbohydrate metabolic process GO:0044723 237 0.027
regulation of cellular protein catabolic process GO:1903362 36 0.027
protein dna complex subunit organization GO:0071824 153 0.027
attachment of mitotic spindle microtubules to kinetochore GO:0051315 9 0.027
reproduction of a single celled organism GO:0032505 191 0.026
telomere organization GO:0032200 75 0.026
protein dna complex assembly GO:0065004 105 0.026
reciprocal meiotic recombination GO:0007131 54 0.025
heterocycle catabolic process GO:0046700 494 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.025
negative regulation of proteasomal protein catabolic process GO:1901799 25 0.025
signal transduction GO:0007165 208 0.025
mitotic spindle organization GO:0007052 30 0.024
nucleobase containing compound catabolic process GO:0034655 479 0.024
meiotic chromosome condensation GO:0010032 2 0.024
protein localization to chromosome GO:0034502 28 0.024
modification dependent protein catabolic process GO:0019941 181 0.024
positive regulation of rna biosynthetic process GO:1902680 286 0.024
negative regulation of mitosis GO:0045839 39 0.023
nucleus organization GO:0006997 62 0.023
nuclear rna surveillance GO:0071027 30 0.023
cellular amine metabolic process GO:0044106 51 0.023
negative regulation of protein catabolic process GO:0042177 27 0.023
maintenance of location GO:0051235 66 0.023
response to oxidative stress GO:0006979 99 0.022
regulation of protein metabolic process GO:0051246 237 0.022
cellular response to oxidative stress GO:0034599 94 0.022
mitotic recombination GO:0006312 55 0.022
response to uv GO:0009411 4 0.022
cell development GO:0048468 107 0.022
negative regulation of transferase activity GO:0051348 31 0.021
response to abiotic stimulus GO:0009628 159 0.021
reproductive process in single celled organism GO:0022413 145 0.021
negative regulation of protein processing GO:0010955 33 0.021
regulation of transcription by chromatin organization GO:0034401 19 0.021
sexual reproduction GO:0019953 216 0.021
aging GO:0007568 71 0.021
dna catabolic process GO:0006308 42 0.021
nucleoside metabolic process GO:0009116 394 0.020
dna replication initiation GO:0006270 48 0.020
protein sumoylation GO:0016925 17 0.020
positive regulation of biosynthetic process GO:0009891 336 0.020
positive regulation of organelle organization GO:0010638 85 0.020
microtubule based process GO:0007017 117 0.020
nucleobase containing small molecule metabolic process GO:0055086 491 0.020
fungal type cell wall organization or biogenesis GO:0071852 169 0.019
organic hydroxy compound metabolic process GO:1901615 125 0.019
protein ubiquitination GO:0016567 118 0.019
dna recombination GO:0006310 172 0.019
response to nutrient levels GO:0031667 150 0.019
negative regulation of cellular catabolic process GO:0031330 43 0.019
organophosphate metabolic process GO:0019637 597 0.019
nuclear import GO:0051170 57 0.019
cellular response to dna damage stimulus GO:0006974 287 0.018
glycosyl compound metabolic process GO:1901657 398 0.018
dna templated transcription initiation GO:0006352 71 0.018
amine metabolic process GO:0009308 51 0.018
establishment of spindle localization GO:0051293 14 0.018
regulation of cellular catabolic process GO:0031329 195 0.018
carboxylic acid metabolic process GO:0019752 338 0.018
purine nucleoside metabolic process GO:0042278 380 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.018
organic cyclic compound catabolic process GO:1901361 499 0.018
regulation of cellular amino acid metabolic process GO:0006521 16 0.018
dna integrity checkpoint GO:0031570 41 0.018
response to organic cyclic compound GO:0014070 1 0.018
regulation of proteasomal protein catabolic process GO:0061136 34 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
cleavage involved in rrna processing GO:0000469 69 0.017
mrna transport GO:0051028 60 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.017
regulation of cell cycle g2 m phase transition GO:1902749 8 0.017
organophosphate biosynthetic process GO:0090407 182 0.016
regulation of chromatin organization GO:1902275 23 0.016
organelle inheritance GO:0048308 51 0.016
regulation of dna replication GO:0006275 51 0.016
response to osmotic stress GO:0006970 83 0.016
recombinational repair GO:0000725 64 0.016
cellular lipid metabolic process GO:0044255 229 0.016
atp catabolic process GO:0006200 224 0.016
purine nucleotide catabolic process GO:0006195 328 0.016
carbohydrate derivative metabolic process GO:1901135 549 0.016
single organism carbohydrate catabolic process GO:0044724 73 0.016
mrna processing GO:0006397 185 0.016
endomembrane system organization GO:0010256 74 0.016
mitotic dna integrity checkpoint GO:0044774 18 0.016
nucleoside monophosphate catabolic process GO:0009125 224 0.016
protein complex assembly GO:0006461 302 0.016
protein complex localization GO:0031503 32 0.016
endoplasmic reticulum organization GO:0007029 30 0.015
double strand break repair via homologous recombination GO:0000724 54 0.015
establishment of organelle localization GO:0051656 96 0.015
cellular protein complex localization GO:0034629 28 0.015
cell wall organization or biogenesis GO:0071554 190 0.015
positive regulation of transcription dna templated GO:0045893 286 0.015
regulation of dna dependent dna replication GO:0090329 37 0.015
ubiquitin dependent protein catabolic process GO:0006511 181 0.015
posttranscriptional regulation of gene expression GO:0010608 115 0.015
chromatin silencing at telomere GO:0006348 84 0.015
nucleotide metabolic process GO:0009117 453 0.015
positive regulation of molecular function GO:0044093 185 0.015
chromosome localization GO:0050000 20 0.015
detection of stimulus GO:0051606 4 0.015
rna export from nucleus GO:0006405 88 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
maintenance of location in cell GO:0051651 58 0.014
negative regulation of catabolic process GO:0009895 43 0.014
purine nucleoside monophosphate metabolic process GO:0009126 262 0.014
positive regulation of macromolecule metabolic process GO:0010604 394 0.014
developmental process involved in reproduction GO:0003006 159 0.014
organic acid metabolic process GO:0006082 352 0.014
protein homotetramerization GO:0051289 1 0.014
regulation of g2 m transition of mitotic cell cycle GO:0010389 8 0.014
heterochromatin organization GO:0070828 11 0.014
rna dependent dna replication GO:0006278 25 0.014
protein localization to nucleus GO:0034504 74 0.014
filamentous growth GO:0030447 124 0.014
negative regulation of molecular function GO:0044092 68 0.014
single organism reproductive process GO:0044702 159 0.014
purine containing compound metabolic process GO:0072521 400 0.013
telomere maintenance via telomerase GO:0007004 21 0.013
conjugation with cellular fusion GO:0000747 106 0.013
negative regulation of catalytic activity GO:0043086 60 0.013
mitotic spindle checkpoint GO:0071174 34 0.013
nucleic acid transport GO:0050657 94 0.013
ribosome biogenesis GO:0042254 335 0.013
positive regulation of intracellular transport GO:0032388 4 0.013
ribonucleoside catabolic process GO:0042454 332 0.013
negative regulation of dna metabolic process GO:0051053 36 0.013
atp metabolic process GO:0046034 251 0.013
mitochondrion organization GO:0007005 261 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.013
regulation of cellular ketone metabolic process GO:0010565 42 0.013
meiotic sister chromatid segregation GO:0045144 14 0.013
response to starvation GO:0042594 96 0.013
response to cell cycle checkpoint signaling GO:0072396 8 0.013
nucleoside catabolic process GO:0009164 335 0.012
positive regulation of cell cycle process GO:0090068 31 0.012
external encapsulating structure organization GO:0045229 146 0.012
nuclear retention of pre mrna at the site of transcription GO:0071033 9 0.012
positive regulation of cell cycle GO:0045787 32 0.012
purine nucleoside triphosphate catabolic process GO:0009146 329 0.012
purine nucleoside monophosphate catabolic process GO:0009128 224 0.012
detection of chemical stimulus GO:0009593 3 0.012
organelle localization GO:0051640 128 0.012
regulation of purine nucleotide metabolic process GO:1900542 109 0.012
cell aging GO:0007569 70 0.012
attachment of spindle microtubules to kinetochore GO:0008608 25 0.012
purine nucleotide metabolic process GO:0006163 376 0.012
rrna processing GO:0006364 227 0.012
cellular ketone metabolic process GO:0042180 63 0.012
internal peptidyl lysine acetylation GO:0018393 52 0.012
gene silencing by rna GO:0031047 3 0.012
spindle checkpoint GO:0031577 35 0.012
multi organism process GO:0051704 233 0.012
maintenance of rdna GO:0043007 9 0.012
anatomical structure formation involved in morphogenesis GO:0048646 136 0.012
maintenance of protein location in cell GO:0032507 50 0.012
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.011
response to extracellular stimulus GO:0009991 156 0.011
carbohydrate derivative biosynthetic process GO:1901137 181 0.011
cell communication GO:0007154 345 0.011
reciprocal dna recombination GO:0035825 54 0.011
regulation of gene silencing GO:0060968 41 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.011
macroautophagy GO:0016236 55 0.011
organonitrogen compound catabolic process GO:1901565 404 0.011
positive regulation of cellular component organization GO:0051130 116 0.011
positive regulation of nucleic acid templated transcription GO:1903508 286 0.011
positive regulation of chromosome organization GO:2001252 20 0.011
nucleoside phosphate metabolic process GO:0006753 458 0.011
nucleoside triphosphate biosynthetic process GO:0009142 22 0.011
positive regulation of mitotic metaphase anaphase transition GO:0045842 3 0.011
error prone translesion synthesis GO:0042276 11 0.011
protein monoubiquitination GO:0006513 13 0.011
ion homeostasis GO:0050801 118 0.011
cellular modified amino acid metabolic process GO:0006575 51 0.011
negative regulation of proteolysis GO:0045861 33 0.011
transition metal ion homeostasis GO:0055076 59 0.011
peptidyl lysine modification GO:0018205 77 0.011
gtp metabolic process GO:0046039 107 0.011
regulation of dna templated transcription initiation GO:2000142 19 0.011
regulation of response to drug GO:2001023 3 0.010
developmental growth GO:0048589 3 0.010
cofactor metabolic process GO:0051186 126 0.010
nucleoside triphosphate metabolic process GO:0009141 364 0.010
coenzyme biosynthetic process GO:0009108 66 0.010
regulation of cellular localization GO:0060341 50 0.010
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.010
mating type switching GO:0007533 28 0.010
regulation of proteolysis GO:0030162 44 0.010
single organism developmental process GO:0044767 258 0.010
purine ribonucleoside metabolic process GO:0046128 380 0.010
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.010
pre replicative complex assembly involved in nuclear cell cycle dna replication GO:0006267 20 0.010
regulation of metal ion transport GO:0010959 2 0.010
response to hypoxia GO:0001666 4 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.010
cellular response to extracellular stimulus GO:0031668 150 0.010
poly a mrna export from nucleus GO:0016973 24 0.010

SMC4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org