Saccharomyces cerevisiae

86 known processes

ITC1 (YGL133W)

Itc1p

ITC1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.892
negative regulation of cellular biosynthetic process GO:0031327 312 0.735
chromatin organization GO:0006325 242 0.707
chromatin remodeling GO:0006338 80 0.689
transcription from rna polymerase i promoter GO:0006360 63 0.651
chromatin modification GO:0016568 200 0.639
negative regulation of rna metabolic process GO:0051253 262 0.636
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.631
negative regulation of biosynthetic process GO:0009890 312 0.627
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.607
chromatin silencing GO:0006342 147 0.524
positive regulation of transcription dna templated GO:0045893 286 0.517
cellular response to pheromone GO:0071444 88 0.505
nucleoside triphosphate metabolic process GO:0009141 364 0.505
positive regulation of nucleic acid templated transcription GO:1903508 286 0.500
cellular nitrogen compound catabolic process GO:0044270 494 0.489
positive regulation of filamentous growth of a population of unicellular organisms GO:1900430 18 0.454
negative regulation of gene expression epigenetic GO:0045814 147 0.422
negative regulation of cellular metabolic process GO:0031324 407 0.417
cell communication GO:0007154 345 0.403
organonitrogen compound catabolic process GO:1901565 404 0.401
negative regulation of transcription dna templated GO:0045892 258 0.401
negative regulation of nucleic acid templated transcription GO:1903507 260 0.396
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.377
growth GO:0040007 157 0.376
nucleobase containing compound catabolic process GO:0034655 479 0.363
chromatin assembly GO:0031497 35 0.352
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.347
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.347
negative regulation of rna biosynthetic process GO:1902679 260 0.335
purine ribonucleotide metabolic process GO:0009150 372 0.330
purine nucleotide catabolic process GO:0006195 328 0.310
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.310
carbohydrate derivative metabolic process GO:1901135 549 0.302
ribonucleoside metabolic process GO:0009119 389 0.298
positive regulation of cellular biosynthetic process GO:0031328 336 0.298
heterocycle catabolic process GO:0046700 494 0.296
glycosyl compound metabolic process GO:1901657 398 0.289
ribonucleotide catabolic process GO:0009261 327 0.278
cellular response to chemical stimulus GO:0070887 315 0.277
positive regulation of gene expression GO:0010628 321 0.274
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.271
regulation of gene expression epigenetic GO:0040029 147 0.258
nucleobase containing small molecule metabolic process GO:0055086 491 0.256
regulation of transcription by chromatin organization GO:0034401 19 0.256
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.254
protein dna complex subunit organization GO:0071824 153 0.254
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.253
positive regulation of biosynthetic process GO:0009891 336 0.253
response to external stimulus GO:0009605 158 0.233
ribonucleoside catabolic process GO:0042454 332 0.231
filamentous growth of a population of unicellular organisms GO:0044182 109 0.220
gene silencing GO:0016458 151 0.210
purine nucleoside metabolic process GO:0042278 380 0.209
negative regulation of macromolecule metabolic process GO:0010605 375 0.200
single organism catabolic process GO:0044712 619 0.195
nucleotide metabolic process GO:0009117 453 0.193
carboxylic acid metabolic process GO:0019752 338 0.193
single organism signaling GO:0044700 208 0.191
positive regulation of rna metabolic process GO:0051254 294 0.188
oxoacid metabolic process GO:0043436 351 0.184
organophosphate metabolic process GO:0019637 597 0.177
regulation of protein complex assembly GO:0043254 77 0.176
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.173
nucleoside phosphate metabolic process GO:0006753 458 0.173
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.172
nucleoside triphosphate catabolic process GO:0009143 329 0.170
signal transduction GO:0007165 208 0.169
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.168
negative regulation of gene expression GO:0010629 312 0.161
small molecule biosynthetic process GO:0044283 258 0.160
dna conformation change GO:0071103 98 0.158
purine nucleoside triphosphate metabolic process GO:0009144 356 0.154
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.154
dna dependent dna replication GO:0006261 115 0.153
lipid metabolic process GO:0006629 269 0.149
nucleoside phosphate catabolic process GO:1901292 331 0.147
organophosphate catabolic process GO:0046434 338 0.147
protein complex assembly GO:0006461 302 0.145
aromatic compound catabolic process GO:0019439 491 0.145
cellular response to organic substance GO:0071310 159 0.145
positive regulation of rna biosynthetic process GO:1902680 286 0.143
dna templated transcription elongation GO:0006354 91 0.142
organic acid biosynthetic process GO:0016053 152 0.140
dna repair GO:0006281 236 0.137
cellular amino acid metabolic process GO:0006520 225 0.136
histone modification GO:0016570 119 0.135
organic hydroxy compound metabolic process GO:1901615 125 0.132
response to extracellular stimulus GO:0009991 156 0.131
purine nucleoside catabolic process GO:0006152 330 0.128
lipid biosynthetic process GO:0008610 170 0.128
multi organism process GO:0051704 233 0.120
single organism developmental process GO:0044767 258 0.118
phytosteroid metabolic process GO:0016128 31 0.118
response to oxidative stress GO:0006979 99 0.113
organic cyclic compound catabolic process GO:1901361 499 0.111
regulation of response to stress GO:0080134 57 0.109
sterol metabolic process GO:0016125 47 0.107
purine nucleoside triphosphate catabolic process GO:0009146 329 0.107
nucleosome organization GO:0034728 63 0.104
cellular alcohol metabolic process GO:0044107 34 0.102
glycosyl compound catabolic process GO:1901658 335 0.100
protein complex biogenesis GO:0070271 314 0.100
cellular response to oxidative stress GO:0034599 94 0.099
positive regulation of macromolecule metabolic process GO:0010604 394 0.099
signaling GO:0023052 208 0.098
response to nutrient levels GO:0031667 150 0.097
carbohydrate derivative catabolic process GO:1901136 339 0.097
negative regulation of chromosome organization GO:2001251 39 0.096
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 33 0.094
filamentous growth GO:0030447 124 0.092
cellular lipid metabolic process GO:0044255 229 0.088
dna packaging GO:0006323 55 0.083
nucleoside metabolic process GO:0009116 394 0.082
steroid metabolic process GO:0008202 47 0.081
response to chemical GO:0042221 390 0.081
dna replication GO:0006260 147 0.081
nucleosome mobilization GO:0042766 11 0.079
regulation of cellular catabolic process GO:0031329 195 0.076
covalent chromatin modification GO:0016569 119 0.073
regulation of chromatin organization GO:1902275 23 0.073
regulation of response to stimulus GO:0048583 157 0.071
nucleosome positioning GO:0016584 10 0.070
negative regulation of chromatin modification GO:1903309 9 0.070
regulation of transcription by pheromones GO:0009373 14 0.068
regulation of biological quality GO:0065008 391 0.068
nucleoside catabolic process GO:0009164 335 0.067
positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436 4 0.067
response to abiotic stimulus GO:0009628 159 0.066
developmental process GO:0032502 261 0.066
regulation of cellular component biogenesis GO:0044087 112 0.065
regulation of chromatin modification GO:1903308 23 0.064
ergosterol metabolic process GO:0008204 31 0.063
nucleotide catabolic process GO:0009166 330 0.063
dna templated transcription termination GO:0006353 42 0.063
positive regulation of cellular catabolic process GO:0031331 128 0.062
negative regulation of organelle organization GO:0010639 103 0.061
organic acid metabolic process GO:0006082 352 0.059
invasive filamentous growth GO:0036267 65 0.058
regulation of dna templated transcription in response to stress GO:0043620 51 0.058
negative regulation of response to salt stress GO:1901001 2 0.058
positive regulation of transcription from rna polymerase ii promoter by oleic acid GO:0061429 4 0.058
carboxylic acid catabolic process GO:0046395 71 0.054
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 22 0.054
response to pheromone GO:0019236 92 0.053
cellular response to extracellular stimulus GO:0031668 150 0.053
small molecule catabolic process GO:0044282 88 0.053
regulation of response to nutrient levels GO:0032107 20 0.051
positive regulation of filamentous growth GO:0090033 18 0.051
developmental process involved in reproduction GO:0003006 159 0.050
cellular response to external stimulus GO:0071496 150 0.049
cellular response to nutrient GO:0031670 50 0.048
cellular ketone metabolic process GO:0042180 63 0.046
purine containing compound catabolic process GO:0072523 332 0.045
ribonucleotide metabolic process GO:0009259 377 0.045
cellular response to nutrient levels GO:0031669 144 0.045
aging GO:0007568 71 0.045
response to starvation GO:0042594 96 0.044
ribonucleoside triphosphate catabolic process GO:0009203 327 0.043
alcohol metabolic process GO:0006066 112 0.043
reproductive process GO:0022414 248 0.042
cellular developmental process GO:0048869 191 0.041
cellular response to heat GO:0034605 53 0.041
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.041
regulation of invasive growth in response to glucose limitation GO:2000217 19 0.040
positive regulation of catalytic activity GO:0043085 178 0.039
cytoskeleton organization GO:0007010 230 0.038
regulation of cellular response to stress GO:0080135 50 0.038
regulation of cellular component organization GO:0051128 334 0.037
nucleoside monophosphate metabolic process GO:0009123 267 0.037
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter GO:1900464 2 0.037
regulation of cellular hyperosmotic salinity response GO:1900069 2 0.037
atp catabolic process GO:0006200 224 0.037
positive regulation of transcription from rna polymerase ii promoter in response to ethanol GO:0061410 3 0.036
purine ribonucleoside catabolic process GO:0046130 330 0.036
response to nutrient GO:0007584 52 0.035
regulation of phosphorus metabolic process GO:0051174 230 0.035
heterochromatin organization GO:0070828 11 0.035
purine ribonucleoside metabolic process GO:0046128 380 0.035
ribonucleoside monophosphate metabolic process GO:0009161 265 0.034
multi organism cellular process GO:0044764 120 0.034
regulation of ethanol catabolic process GO:1900065 1 0.034
purine nucleoside monophosphate metabolic process GO:0009126 262 0.034
positive regulation of molecular function GO:0044093 185 0.034
cell division GO:0051301 205 0.033
positive regulation of growth GO:0045927 19 0.033
atp metabolic process GO:0046034 251 0.033
positive regulation of transcription from rna polymerase ii promoter in response to salt stress GO:0036251 4 0.033
positive regulation of transcription from rna polymerase ii promoter in response to calcium ion GO:0061400 1 0.033
carbon catabolite activation of transcription GO:0045991 26 0.032
mitotic cytokinesis GO:0000281 58 0.032
positive regulation of response to stimulus GO:0048584 37 0.032
establishment of cell polarity GO:0030010 64 0.032
ncrna processing GO:0034470 330 0.032
regulation of molecular function GO:0065009 320 0.031
carboxylic acid biosynthetic process GO:0046394 152 0.031
regulation of potassium ion concentration by positive regulation of transcription from rna polymerase ii promoter GO:0097301 1 0.031
regulation of growth GO:0040008 50 0.031
monocarboxylic acid metabolic process GO:0032787 122 0.031
positive regulation of transcription during mitosis GO:0045897 1 0.031
response to organic substance GO:0010033 182 0.030
cell cycle g1 s phase transition GO:0044843 64 0.030
regulation of transcription from rna polymerase ii promoter by pheromones GO:0046019 14 0.030
multi organism reproductive process GO:0044703 216 0.030
alcohol biosynthetic process GO:0046165 75 0.029
regulation of phosphate metabolic process GO:0019220 230 0.029
single organism reproductive process GO:0044702 159 0.029
mitotic cytokinetic process GO:1902410 45 0.029
regulation of histone exchange GO:1900049 4 0.029
positive regulation of sodium ion transport by positive regulation of transcription from rna polymerase ii promoter GO:0061423 1 0.028
regulation of lipid biosynthetic process GO:0046890 32 0.028
positive regulation of transcription from rna polymerase ii promoter in response to hydrogen peroxide GO:0061407 2 0.028
positive regulation of transcription from rna polymerase ii promoter in response to heat stress GO:0061408 12 0.027
cellular response to starvation GO:0009267 90 0.027
termination of rna polymerase ii transcription GO:0006369 26 0.027
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.027
regulation of dna metabolic process GO:0051052 100 0.027
response to heat GO:0009408 69 0.027
anatomical structure development GO:0048856 160 0.026
ribose phosphate metabolic process GO:0019693 384 0.026
regulation of dna templated transcription initiation GO:2000142 19 0.026
peptidyl lysine acetylation GO:0018394 52 0.026
pseudohyphal growth GO:0007124 75 0.026
protein dna complex assembly GO:0065004 105 0.026
filamentous growth of a population of unicellular organisms in response to starvation GO:0036170 5 0.025
regulation of catabolic process GO:0009894 199 0.025
positive regulation of catabolic process GO:0009896 135 0.025
regulation of cellular protein metabolic process GO:0032268 232 0.025
response to organic cyclic compound GO:0014070 1 0.024
cell aging GO:0007569 70 0.024
regulation of filamentous growth GO:0010570 38 0.024
negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from rna polymerase ii promoter GO:1900460 3 0.024
regulation of organelle organization GO:0033043 243 0.024
ribonucleoside monophosphate catabolic process GO:0009158 224 0.024
cellular response to anoxia GO:0071454 3 0.024
negative regulation of cellular component organization GO:0051129 109 0.024
regulation of developmental process GO:0050793 30 0.024
reproductive process in single celled organism GO:0022413 145 0.024
g1 s transition of mitotic cell cycle GO:0000082 64 0.024
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter GO:0072366 10 0.023
chromatin silencing at rdna GO:0000183 32 0.023
chromatin silencing at telomere GO:0006348 84 0.023
purine containing compound metabolic process GO:0072521 400 0.023
response to osmotic stress GO:0006970 83 0.023
positive regulation of transcription from rna polymerase ii promoter in response to zinc ion starvation GO:0097236 3 0.022
positive regulation of transcription from rna polymerase ii promoter in response to cold GO:0061411 2 0.022
regulation of chromosome organization GO:0033044 66 0.022
sexual reproduction GO:0019953 216 0.022
response to temperature stimulus GO:0009266 74 0.022
positive regulation of transcription from rna polymerase ii promoter in response to acidic ph GO:0061402 4 0.022
regulation of cell cycle GO:0051726 195 0.022
cellular response to oxygen containing compound GO:1901701 43 0.021
peptidyl amino acid modification GO:0018193 116 0.021
protein modification by small protein conjugation or removal GO:0070647 172 0.021
regulation of protein modification process GO:0031399 110 0.021
vesicle mediated transport GO:0016192 335 0.021
ribonucleoside triphosphate metabolic process GO:0009199 356 0.021
positive regulation of transcription on exit from mitosis GO:0007072 1 0.020
surface biofilm formation GO:0090604 3 0.020
atp dependent chromatin remodeling GO:0043044 36 0.020
regulation of cellular ketone metabolic process GO:0010565 42 0.020
carbon catabolite regulation of transcription GO:0045990 39 0.020
mitotic cell cycle phase transition GO:0044772 141 0.020
regulation of response to extracellular stimulus GO:0032104 20 0.020
fungal type cell wall organization or biogenesis GO:0071852 169 0.019
positive regulation of transcription from rna polymerase ii promoter in response to glucose starvation GO:0061406 2 0.019
regulation of cell cycle process GO:0010564 150 0.019
invasive growth in response to glucose limitation GO:0001403 61 0.019
positive regulation of cellular response to drug GO:2001040 3 0.019
positive regulation of sodium ion transport GO:0010765 1 0.019
regulation of metal ion transport GO:0010959 2 0.019
response to nitrosative stress GO:0051409 3 0.018
positive regulation of response to drug GO:2001025 3 0.018
cellular response to zinc ion starvation GO:0034224 3 0.018
cellular amine metabolic process GO:0044106 51 0.018
conjugation GO:0000746 107 0.018
positive regulation of sulfite transport by positive regulation of transcription from rna polymerase ii promoter GO:0061426 1 0.018
single organism carbohydrate catabolic process GO:0044724 73 0.018
regulation of purine nucleotide catabolic process GO:0033121 106 0.017
sporulation GO:0043934 132 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.017
organic hydroxy compound biosynthetic process GO:1901617 81 0.017
positive regulation of nucleotide metabolic process GO:0045981 101 0.017
purine nucleotide metabolic process GO:0006163 376 0.017
reproduction of a single celled organism GO:0032505 191 0.017
regulation of response to external stimulus GO:0032101 20 0.017
nucleoside monophosphate catabolic process GO:0009125 224 0.017
response to calcium ion GO:0051592 1 0.016
dna templated transcriptional start site selection GO:0001173 7 0.016
single species surface biofilm formation GO:0090606 3 0.016
cellular lipid catabolic process GO:0044242 33 0.016
protein catabolic process GO:0030163 221 0.016
peptidyl lysine modification GO:0018205 77 0.016
anatomical structure morphogenesis GO:0009653 160 0.016
cellular response to osmotic stress GO:0071470 50 0.015
regulation of nucleotide catabolic process GO:0030811 106 0.015
cellular response to abiotic stimulus GO:0071214 62 0.015
sex determination GO:0007530 32 0.015
cellular ion homeostasis GO:0006873 112 0.015
negative regulation of cell cycle GO:0045786 91 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.015
cellular alcohol biosynthetic process GO:0044108 29 0.015
negative regulation of growth of unicellular organism as a thread of attached cells GO:0070785 11 0.015
regulation of transcription from rna polymerase ii promoter in response to zinc ion starvation GO:0034225 3 0.015
fungal type cell wall organization GO:0031505 145 0.015
positive regulation of transcription from rna polymerase ii promoter in response to alkaline ph GO:0061422 3 0.014
cellular hypotonic response GO:0071476 2 0.014
negative regulation of steroid biosynthetic process GO:0010894 1 0.014
death GO:0016265 30 0.014
dna templated transcription initiation GO:0006352 71 0.014
positive regulation of response to nutrient levels GO:0032109 12 0.014
positive regulation of transcription from rna polymerase ii promoter in response to nitrosative stress GO:0061403 2 0.014
regulation of replicative cell aging by regulation of transcription from rna polymerase ii promoter in response to caloric restriction GO:0061434 2 0.014
sexual sporulation GO:0034293 113 0.014
cytoskeleton dependent cytokinesis GO:0061640 65 0.014
protein acylation GO:0043543 66 0.014
positive regulation of phosphate metabolic process GO:0045937 147 0.014
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 12 0.013
negative regulation of steroid metabolic process GO:0045939 1 0.013
regulation of catalytic activity GO:0050790 307 0.013
ribonucleoprotein complex subunit organization GO:0071826 152 0.013
sporulation resulting in formation of a cellular spore GO:0030435 129 0.013
establishment or maintenance of cell polarity GO:0007163 96 0.013
response to blue light GO:0009637 2 0.013
regulation of response to salt stress GO:1901000 2 0.013
homeostatic process GO:0042592 227 0.013
negative regulation of transcription by chromatin organization GO:0097549 1 0.013
rrna metabolic process GO:0016072 244 0.013
positive regulation of transcription from rna polymerase ii promoter in response to amino acid starvation GO:0061412 5 0.013
regulation of cell division GO:0051302 113 0.013
rna export from nucleus GO:0006405 88 0.013
sulfite transport GO:0000316 2 0.013
negative regulation of cellular response to alkaline ph by negative regulation of transcription from rna polymerase ii promoter GO:1900463 1 0.013
regulation of cytokinetic cell separation GO:0010590 1 0.013
regulation of intracellular signal transduction GO:1902531 78 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.012
purine ribonucleotide catabolic process GO:0009154 327 0.012
mating type switching GO:0007533 28 0.012
positive regulation of peroxisome organization GO:1900064 1 0.012
negative regulation of filamentous growth of a population of unicellular organisms GO:1900429 12 0.012
positive regulation of transcription from rna polymerase ii promoter by calcium mediated signaling GO:1900622 1 0.012
posttranscriptional regulation of gene expression GO:0010608 115 0.012
positive regulation of transcription by oleic acid GO:0061421 4 0.012
phospholipid biosynthetic process GO:0008654 89 0.012
nucleosome assembly GO:0006334 16 0.012
mitotic cell cycle GO:0000278 306 0.012
cellular response to dna damage stimulus GO:0006974 287 0.012
cation homeostasis GO:0055080 105 0.012
regulation of lipid catabolic process GO:0050994 4 0.012
cell morphogenesis GO:0000902 30 0.012
positive regulation of fatty acid oxidation GO:0046321 3 0.011
chronological cell aging GO:0001300 28 0.011
regulation of response to drug GO:2001023 3 0.011
exit from mitosis GO:0010458 37 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.011
regulation of lipid metabolic process GO:0019216 45 0.011
cellular response to nitrosative stress GO:0071500 2 0.011
negative regulation of transcription from rna polymerase ii promoter by pheromones GO:0046020 10 0.011
ascospore formation GO:0030437 107 0.011
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.011
regulation of peroxisome organization GO:1900063 1 0.011
positive regulation of fatty acid beta oxidation by positive regulation of transcription from rna polymerase ii promoter GO:0097235 1 0.011
transcriptional start site selection at rna polymerase ii promoter GO:0001174 7 0.011
transfer rna gene mediated silencing GO:0061587 14 0.011
response to oxygen containing compound GO:1901700 61 0.011
chromatin assembly or disassembly GO:0006333 60 0.011
response to inorganic substance GO:0010035 47 0.011
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 26 0.011
cellular protein complex assembly GO:0043623 209 0.011
protein deacylation GO:0035601 27 0.010
cellular response to caloric restriction GO:0061433 2 0.010
regulation of localization GO:0032879 127 0.010
translation GO:0006412 230 0.010
regulation of cellular response to drug GO:2001038 3 0.010
mitotic nuclear division GO:0007067 131 0.010
regulation of transcription from rna polymerase ii promoter in response to osmotic stress GO:0061392 9 0.010
response to hydrostatic pressure GO:0051599 2 0.010
positive regulation of nucleoside metabolic process GO:0045979 97 0.010
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage GO:0010767 1 0.010
sterol biosynthetic process GO:0016126 35 0.010

ITC1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org