Saccharomyces cerevisiae

137 known processes

MRC1 (YCL061C)

Mrc1p

(Aliases: YCL060C)

MRC1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dna dependent dna replication GO:0006261 115 0.997
dna replication GO:0006260 147 0.987
double strand break repair GO:0006302 105 0.964
dna repair GO:0006281 236 0.955
cellular response to dna damage stimulus GO:0006974 287 0.940
double strand break repair via homologous recombination GO:0000724 54 0.938
recombinational repair GO:0000725 64 0.910
mitotic cell cycle GO:0000278 306 0.884
sister chromatid cohesion GO:0007062 49 0.874
mitotic cell cycle process GO:1903047 294 0.873
dna replication initiation GO:0006270 48 0.857
double strand break repair via break induced replication GO:0000727 25 0.840
mitotic sister chromatid cohesion GO:0007064 38 0.830
negative regulation of cellular biosynthetic process GO:0031327 312 0.782
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.764
negative regulation of biosynthetic process GO:0009890 312 0.762
dna dependent dna replication maintenance of fidelity GO:0045005 14 0.721
negative regulation of macromolecule metabolic process GO:0010605 375 0.717
negative regulation of cellular metabolic process GO:0031324 407 0.698
mitotic sister chromatid segregation GO:0000070 85 0.694
dna strand elongation involved in dna replication GO:0006271 26 0.681
negative regulation of dna metabolic process GO:0051053 36 0.585
cell cycle checkpoint GO:0000075 82 0.495
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.488
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.426
dna integrity checkpoint GO:0031570 41 0.396
organelle fission GO:0048285 272 0.394
regulation of dna metabolic process GO:0051052 100 0.386
chromosome segregation GO:0007059 159 0.379
single organism developmental process GO:0044767 258 0.358
replication fork protection GO:0048478 6 0.356
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.348
sister chromatid segregation GO:0000819 93 0.321
nuclear division GO:0000280 263 0.318
mitotic nuclear division GO:0007067 131 0.311
regulation of dna replication GO:0006275 51 0.291
dna recombination GO:0006310 172 0.276
negative regulation of mitotic cell cycle GO:0045930 63 0.275
negative regulation of cell cycle process GO:0010948 86 0.249
phosphorylation GO:0016310 291 0.245
negative regulation of dna replication GO:0008156 15 0.242
regulation of cell cycle GO:0051726 195 0.222
regulation of catalytic activity GO:0050790 307 0.201
developmental process GO:0032502 261 0.195
negative regulation of dna dependent dna replication GO:2000104 8 0.189
regulation of cell cycle process GO:0010564 150 0.187
lagging strand elongation GO:0006273 10 0.184
organic cyclic compound catabolic process GO:1901361 499 0.183
dna damage checkpoint GO:0000077 29 0.183
regulation of cellular component organization GO:0051128 334 0.171
dna conformation change GO:0071103 98 0.158
aromatic compound catabolic process GO:0019439 491 0.157
regulation of mitotic cell cycle GO:0007346 107 0.154
negative regulation of cell cycle GO:0045786 91 0.151
dna strand elongation GO:0022616 29 0.149
cell cycle phase transition GO:0044770 144 0.149
reproductive process GO:0022414 248 0.143
negative regulation of gene expression GO:0010629 312 0.136
nucleobase containing small molecule metabolic process GO:0055086 491 0.135
cell differentiation GO:0030154 161 0.131
cell cycle dna replication GO:0044786 36 0.129
organophosphate biosynthetic process GO:0090407 182 0.126
cellular developmental process GO:0048869 191 0.123
negative regulation of rna metabolic process GO:0051253 262 0.120
nucleobase containing compound catabolic process GO:0034655 479 0.120
regulation of protein metabolic process GO:0051246 237 0.117
maintenance of dna repeat elements GO:0043570 20 0.115
nucleotide metabolic process GO:0009117 453 0.114
cellular nitrogen compound catabolic process GO:0044270 494 0.112
mitotic cell cycle phase transition GO:0044772 141 0.111
regulation of phosphorus metabolic process GO:0051174 230 0.111
heterocycle catabolic process GO:0046700 494 0.109
dna catabolic process GO:0006308 42 0.107
mitotic cell cycle checkpoint GO:0007093 56 0.106
fungal type cell wall organization GO:0031505 145 0.106
nucleoside phosphate metabolic process GO:0006753 458 0.104
purine nucleoside triphosphate catabolic process GO:0009146 329 0.104
protein dna complex subunit organization GO:0071824 153 0.100
regulation of molecular function GO:0065009 320 0.096
negative regulation of cell cycle phase transition GO:1901988 59 0.092
reproduction of a single celled organism GO:0032505 191 0.088
ribonucleoside triphosphate catabolic process GO:0009203 327 0.084
mitotic dna integrity checkpoint GO:0044774 18 0.084
protein complex biogenesis GO:0070271 314 0.084
nucleoside phosphate biosynthetic process GO:1901293 80 0.083
regulation of dna dependent dna replication GO:0090329 37 0.083
non recombinational repair GO:0000726 33 0.082
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.077
negative regulation of nucleic acid templated transcription GO:1903507 260 0.077
ribonucleotide catabolic process GO:0009261 327 0.077
regulation of cell cycle phase transition GO:1901987 70 0.077
negative regulation of gene expression epigenetic GO:0045814 147 0.076
anatomical structure morphogenesis GO:0009653 160 0.076
reproductive process in single celled organism GO:0022413 145 0.075
regulation of cellular catabolic process GO:0031329 195 0.075
protein phosphorylation GO:0006468 197 0.073
peptidyl amino acid modification GO:0018193 116 0.072
protein complex assembly GO:0006461 302 0.068
growth GO:0040007 157 0.068
negative regulation of transcription dna templated GO:0045892 258 0.067
dna duplex unwinding GO:0032508 42 0.066
carbohydrate derivative catabolic process GO:1901136 339 0.066
negative regulation of mitotic cell cycle phase transition GO:1901991 57 0.064
organophosphate metabolic process GO:0019637 597 0.061
negative regulation of rna biosynthetic process GO:1902679 260 0.060
dna unwinding involved in dna replication GO:0006268 13 0.059
regulation of meiotic cell cycle GO:0051445 43 0.058
glycosyl compound catabolic process GO:1901658 335 0.058
regulation of purine nucleotide catabolic process GO:0033121 106 0.056
regulation of mitotic cell cycle phase transition GO:1901990 68 0.054
cell wall organization GO:0071555 146 0.054
establishment of mitotic sister chromatid cohesion GO:0034087 15 0.052
response to chemical GO:0042221 390 0.052
organophosphate catabolic process GO:0046434 338 0.052
establishment of protein localization to organelle GO:0072594 278 0.051
nucleoside triphosphate catabolic process GO:0009143 329 0.051
purine nucleoside monophosphate metabolic process GO:0009126 262 0.050
multi organism reproductive process GO:0044703 216 0.050
carbohydrate derivative metabolic process GO:1901135 549 0.049
regulation of cellular protein metabolic process GO:0032268 232 0.049
multi organism process GO:0051704 233 0.049
purine nucleoside catabolic process GO:0006152 330 0.049
regulation of catabolic process GO:0009894 199 0.048
purine ribonucleotide catabolic process GO:0009154 327 0.048
purine nucleotide catabolic process GO:0006195 328 0.048
positive regulation of molecular function GO:0044093 185 0.048
positive regulation of cellular protein metabolic process GO:0032270 89 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.047
rna dependent dna replication GO:0006278 25 0.047
chromatin silencing at telomere GO:0006348 84 0.046
nucleotide catabolic process GO:0009166 330 0.045
nucleoside triphosphate metabolic process GO:0009141 364 0.044
purine ribonucleoside metabolic process GO:0046128 380 0.044
regulation of mitosis GO:0007088 65 0.043
regulation of protein kinase activity GO:0045859 67 0.043
positive regulation of protein metabolic process GO:0051247 93 0.043
conjugation with cellular fusion GO:0000747 106 0.042
base excision repair GO:0006284 14 0.042
regulation of protein phosphorylation GO:0001932 75 0.042
negative regulation of phosphate metabolic process GO:0045936 49 0.042
regulation of phosphate metabolic process GO:0019220 230 0.042
purine ribonucleoside catabolic process GO:0046130 330 0.041
chromatin assembly or disassembly GO:0006333 60 0.041
negative regulation of cell cycle g2 m phase transition GO:1902750 5 0.039
mitochondrial genome maintenance GO:0000002 40 0.039
chromatin silencing at silent mating type cassette GO:0030466 53 0.039
regulation of dna dependent dna replication initiation GO:0030174 21 0.039
nucleotide excision repair GO:0006289 50 0.038
meiotic chromosome segregation GO:0045132 31 0.038
positive regulation of macromolecule metabolic process GO:0010604 394 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.038
double strand break repair via nonhomologous end joining GO:0006303 27 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.038
chromatin silencing GO:0006342 147 0.037
dna replication removal of rna primer GO:0043137 5 0.037
establishment of sister chromatid cohesion GO:0034085 17 0.036
regulation of hydrolase activity GO:0051336 133 0.035
regulation of g2 m transition of mitotic cell cycle GO:0010389 8 0.034
g2 m transition of mitotic cell cycle GO:0000086 38 0.034
dna biosynthetic process GO:0071897 33 0.034
nuclear import GO:0051170 57 0.034
dna geometric change GO:0032392 43 0.034
regulation of nuclear division GO:0051783 103 0.034
regulation of gene expression epigenetic GO:0040029 147 0.033
positive regulation of phosphate metabolic process GO:0045937 147 0.032
protein autophosphorylation GO:0046777 15 0.032
positive regulation of catalytic activity GO:0043085 178 0.032
regulation of cell cycle g2 m phase transition GO:1902749 8 0.031
regulation of transferase activity GO:0051338 83 0.031
meiotic cell cycle GO:0051321 272 0.030
protein transport GO:0015031 345 0.030
chromatin organization GO:0006325 242 0.030
single organism catabolic process GO:0044712 619 0.029
glycosyl compound metabolic process GO:1901657 398 0.029
positive regulation of nucleic acid templated transcription GO:1903508 286 0.029
single organism cellular localization GO:1902580 375 0.028
regulation of meiosis i GO:0060631 14 0.028
filamentous growth of a population of unicellular organisms GO:0044182 109 0.028
meiotic cell cycle process GO:1903046 229 0.028
purine nucleoside monophosphate catabolic process GO:0009128 224 0.027
endocytosis GO:0006897 90 0.027
histone modification GO:0016570 119 0.027
protein acylation GO:0043543 66 0.027
organelle localization GO:0051640 128 0.026
ribonucleoside catabolic process GO:0042454 332 0.026
regulation of purine nucleotide metabolic process GO:1900542 109 0.025
purine containing compound catabolic process GO:0072523 332 0.025
macromolecule catabolic process GO:0009057 383 0.025
purine nucleoside triphosphate metabolic process GO:0009144 356 0.025
conjugation GO:0000746 107 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.024
ribonucleoside triphosphate metabolic process GO:0009199 356 0.024
regulation of nucleoside metabolic process GO:0009118 106 0.024
protein localization to nucleus GO:0034504 74 0.024
negative regulation of nuclear division GO:0051784 62 0.024
cellular protein complex assembly GO:0043623 209 0.024
anatomical structure development GO:0048856 160 0.023
cellular macromolecule catabolic process GO:0044265 363 0.023
nucleoside metabolic process GO:0009116 394 0.023
purine nucleoside metabolic process GO:0042278 380 0.023
vesicle mediated transport GO:0016192 335 0.022
purine containing compound metabolic process GO:0072521 400 0.022
positive regulation of phosphorus metabolic process GO:0010562 147 0.022
regulation of meiosis GO:0040020 42 0.022
mitotic dna damage checkpoint GO:0044773 11 0.022
regulation of gtp catabolic process GO:0033124 84 0.022
cell communication GO:0007154 345 0.021
atp catabolic process GO:0006200 224 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.021
cellular component disassembly GO:0022411 86 0.021
homeostatic process GO:0042592 227 0.021
glucose metabolic process GO:0006006 65 0.021
cell aging GO:0007569 70 0.021
macromolecular complex disassembly GO:0032984 80 0.020
cell division GO:0051301 205 0.020
regulation of protein modification process GO:0031399 110 0.020
regulation of biological quality GO:0065008 391 0.020
meiotic recombination checkpoint GO:0051598 9 0.020
cell growth GO:0016049 89 0.020
carboxylic acid metabolic process GO:0019752 338 0.020
nucleoside catabolic process GO:0009164 335 0.019
cellular protein catabolic process GO:0044257 213 0.019
nucleoside phosphate catabolic process GO:1901292 331 0.019
positive regulation of cellular catabolic process GO:0031331 128 0.019
purine ribonucleotide metabolic process GO:0009150 372 0.019
gene conversion at mating type locus GO:0007534 11 0.018
nucleoside monophosphate catabolic process GO:0009125 224 0.018
meiosis i GO:0007127 92 0.017
regulation of small gtpase mediated signal transduction GO:0051056 47 0.017
asexual reproduction GO:0019954 48 0.017
telomere maintenance via telomerase GO:0007004 21 0.017
dephosphorylation GO:0016311 127 0.017
negative regulation of cellular component organization GO:0051129 109 0.017
protein targeting to nucleus GO:0044744 57 0.017
positive regulation of catabolic process GO:0009896 135 0.016
meiotic cell cycle checkpoint GO:0033313 10 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.016
regulation of histone acetylation GO:0035065 7 0.016
fungal type cell wall organization or biogenesis GO:0071852 169 0.016
positive regulation of protein kinase activity GO:0045860 22 0.016
organonitrogen compound catabolic process GO:1901565 404 0.015
response to organic cyclic compound GO:0014070 1 0.015
positive regulation of protein modification process GO:0031401 49 0.015
error prone translesion synthesis GO:0042276 11 0.015
cellular homeostasis GO:0019725 138 0.015
regulation of cell communication GO:0010646 124 0.015
establishment of protein localization GO:0045184 367 0.015
positive regulation of gtp catabolic process GO:0033126 80 0.014
response to organic substance GO:0010033 182 0.014
rdna condensation GO:0070550 9 0.014
single organism signaling GO:0044700 208 0.014
negative regulation of meiotic cell cycle GO:0051447 24 0.014
chromatin silencing at rdna GO:0000183 32 0.014
developmental process involved in reproduction GO:0003006 159 0.014
dna replication checkpoint GO:0000076 9 0.014
nitrogen compound transport GO:0071705 212 0.014
protein import GO:0017038 122 0.014
g1 s transition of mitotic cell cycle GO:0000082 64 0.014
cell wall organization or biogenesis GO:0071554 190 0.014
negative regulation of molecular function GO:0044092 68 0.013
positive regulation of biosynthetic process GO:0009891 336 0.013
negative regulation of cell communication GO:0010648 33 0.013
regulation of ras gtpase activity GO:0032318 41 0.013
chromatin modification GO:0016568 200 0.013
dna replication okazaki fragment processing GO:0033567 7 0.013
replicative cell aging GO:0001302 46 0.013
negative regulation of organelle organization GO:0010639 103 0.013
ribonucleoside metabolic process GO:0009119 389 0.012
ribonucleoside monophosphate metabolic process GO:0009161 265 0.012
pre replicative complex assembly involved in nuclear cell cycle dna replication GO:0006267 20 0.012
dna templated transcription elongation GO:0006354 91 0.012
positive regulation of cytoplasmic transport GO:1903651 4 0.012
positive regulation of kinase activity GO:0033674 24 0.012
ribose phosphate metabolic process GO:0019693 384 0.012
budding cell bud growth GO:0007117 29 0.012
rna phosphodiester bond hydrolysis GO:0090501 112 0.012
regulation of cellular response to stress GO:0080135 50 0.012
regulation of transposition rna mediated GO:0010525 15 0.012
regulation of gtpase activity GO:0043087 84 0.012
protein dna complex assembly GO:0065004 105 0.012
positive regulation of phosphorylation GO:0042327 33 0.012
cell budding GO:0007114 48 0.012
lipid metabolic process GO:0006629 269 0.011
cell fate commitment GO:0045165 32 0.011
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 5 0.011
maintenance of dna trinucleotide repeats GO:0035753 8 0.011
nucleocytoplasmic transport GO:0006913 163 0.011
ras protein signal transduction GO:0007265 29 0.011
positive regulation of cell cycle process GO:0090068 31 0.011
nucleosome organization GO:0034728 63 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.011
signaling GO:0023052 208 0.011
chromosome condensation GO:0030261 19 0.011
regulation of nucleotide catabolic process GO:0030811 106 0.011
organonitrogen compound biosynthetic process GO:1901566 314 0.011
negative regulation of phosphorus metabolic process GO:0010563 49 0.011
protein import into nucleus GO:0006606 55 0.011
hexose metabolic process GO:0019318 78 0.010
purine nucleotide metabolic process GO:0006163 376 0.010
nuclear transport GO:0051169 165 0.010
gene silencing GO:0016458 151 0.010
ribonucleoside monophosphate catabolic process GO:0009158 224 0.010
cell cycle g2 m phase transition GO:0044839 39 0.010
pre replicative complex assembly GO:0036388 20 0.010
dna double strand break processing GO:0000729 8 0.010
positive regulation of intracellular transport GO:0032388 4 0.010
meiotic dna double strand break formation GO:0042138 12 0.010

MRC1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011