Saccharomyces cerevisiae

28 known processes

PEP1 (YBL017C)

Pep1p

(Aliases: VPT1,VPS10)

PEP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein localization to organelle GO:0033365 337 0.939
endosomal transport GO:0016197 86 0.716
protein targeting to vacuole GO:0006623 91 0.679
establishment of protein localization GO:0045184 367 0.603
single organism cellular localization GO:1902580 375 0.523
vesicle mediated transport GO:0016192 335 0.441
vacuolar transport GO:0007034 145 0.422
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.386
establishment of protein localization to vacuole GO:0072666 91 0.382
intracellular protein transport GO:0006886 319 0.359
establishment of protein localization to organelle GO:0072594 278 0.341
organelle fission GO:0048285 272 0.339
protein localization to vacuole GO:0072665 92 0.315
post golgi vesicle mediated transport GO:0006892 72 0.303
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.300
protein targeting GO:0006605 272 0.259
nuclear division GO:0000280 263 0.257
regulation of biological quality GO:0065008 391 0.239
Mouse
golgi vesicle transport GO:0048193 188 0.212
transmembrane transport GO:0055085 349 0.196
protein transport GO:0015031 345 0.183
retrograde transport endosome to golgi GO:0042147 33 0.176
late endosome to vacuole transport GO:0045324 42 0.170
meiotic cell cycle GO:0051321 272 0.166
modification dependent macromolecule catabolic process GO:0043632 203 0.143
single organism membrane organization GO:0044802 275 0.129
organelle assembly GO:0070925 118 0.123
membrane organization GO:0061024 276 0.121
single organism catabolic process GO:0044712 619 0.119
regulation of organelle organization GO:0033043 243 0.114
negative regulation of signaling GO:0023057 30 0.100
Mouse
filamentous growth GO:0030447 124 0.096
ion transmembrane transport GO:0034220 200 0.096
lipid metabolic process GO:0006629 269 0.094
macromolecule catabolic process GO:0009057 383 0.080
organophosphate metabolic process GO:0019637 597 0.080
maintenance of protein location in cell GO:0032507 50 0.079
Mouse
translation GO:0006412 230 0.079
response to external stimulus GO:0009605 158 0.073
maintenance of protein location GO:0045185 53 0.069
Mouse
mitotic cell cycle process GO:1903047 294 0.069
ion transport GO:0006811 274 0.069
single organism signaling GO:0044700 208 0.068
Mouse
proteolysis GO:0006508 268 0.068
Mouse
small molecule catabolic process GO:0044282 88 0.067
negative regulation of cellular component organization GO:0051129 109 0.066
Mouse
protein localization to golgi apparatus GO:0034067 13 0.066
Mouse
glycerophospholipid metabolic process GO:0006650 98 0.066
response to nutrient levels GO:0031667 150 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.064
ribosome biogenesis GO:0042254 335 0.062
golgi to endosome transport GO:0006895 17 0.062
mitotic cell cycle GO:0000278 306 0.061
ncrna processing GO:0034470 330 0.061
negative regulation of cellular metabolic process GO:0031324 407 0.059
Mouse
membrane fusion GO:0061025 73 0.059
filamentous growth of a population of unicellular organisms GO:0044182 109 0.058
vacuole organization GO:0007033 75 0.058
cellular protein catabolic process GO:0044257 213 0.057
glycosyl compound metabolic process GO:1901657 398 0.057
negative regulation of cellular biosynthetic process GO:0031327 312 0.056
organic hydroxy compound metabolic process GO:1901615 125 0.055
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.055
cell communication GO:0007154 345 0.055
Mouse
positive regulation of cellular component organization GO:0051130 116 0.055
developmental process GO:0032502 261 0.054
Mouse
purine ribonucleotide catabolic process GO:0009154 327 0.053
ribonucleoside monophosphate metabolic process GO:0009161 265 0.052
cation transmembrane transport GO:0098655 135 0.051
ubiquitin dependent protein catabolic process GO:0006511 181 0.051
nucleobase containing compound catabolic process GO:0034655 479 0.051
carbohydrate metabolic process GO:0005975 252 0.050
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.048
mitotic nuclear division GO:0007067 131 0.047
inorganic cation transmembrane transport GO:0098662 98 0.046
regulation of cellular component organization GO:0051128 334 0.046
Mouse
vesicle organization GO:0016050 68 0.045
negative regulation of cell communication GO:0010648 33 0.045
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.044
Mouse
ribonucleotide metabolic process GO:0009259 377 0.042
negative regulation of transcription dna templated GO:0045892 258 0.042
cellular response to nutrient GO:0031670 50 0.041
cellular lipid metabolic process GO:0044255 229 0.041
nucleobase containing compound transport GO:0015931 124 0.040
generation of precursor metabolites and energy GO:0006091 147 0.040
protein processing GO:0016485 64 0.040
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.040
carbohydrate derivative metabolic process GO:1901135 549 0.040
carbohydrate derivative catabolic process GO:1901136 339 0.039
golgi to vacuole transport GO:0006896 23 0.038
cellular response to extracellular stimulus GO:0031668 150 0.038
cellular respiration GO:0045333 82 0.037
single organism developmental process GO:0044767 258 0.037
Mouse
negative regulation of gene expression GO:0010629 312 0.037
Mouse
transition metal ion transport GO:0000041 45 0.037
response to osmotic stress GO:0006970 83 0.037
single organism carbohydrate metabolic process GO:0044723 237 0.037
phospholipid metabolic process GO:0006644 125 0.036
modification dependent protein catabolic process GO:0019941 181 0.034
organonitrogen compound catabolic process GO:1901565 404 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.034
organic cyclic compound catabolic process GO:1901361 499 0.033
purine nucleotide catabolic process GO:0006195 328 0.033
maintenance of location in cell GO:0051651 58 0.033
Mouse
purine nucleoside metabolic process GO:0042278 380 0.033
cell division GO:0051301 205 0.032
positive regulation of exocytosis GO:0045921 2 0.032
alpha amino acid catabolic process GO:1901606 28 0.032
glycerolipid metabolic process GO:0046486 108 0.031
negative regulation of biosynthetic process GO:0009890 312 0.031
organic acid transport GO:0015849 77 0.031
protein maturation GO:0051604 76 0.030
Mouse
nucleoside phosphate metabolic process GO:0006753 458 0.030
establishment of organelle localization GO:0051656 96 0.029
sporulation resulting in formation of a cellular spore GO:0030435 129 0.029
nucleotide metabolic process GO:0009117 453 0.028
iron ion transport GO:0006826 18 0.028
nucleoside triphosphate metabolic process GO:0009141 364 0.028
purine nucleoside monophosphate metabolic process GO:0009126 262 0.028
response to extracellular stimulus GO:0009991 156 0.028
rrna processing GO:0006364 227 0.027
regulation of protein complex assembly GO:0043254 77 0.027
carbohydrate derivative biosynthetic process GO:1901137 181 0.027
signaling GO:0023052 208 0.027
Mouse
negative regulation of rna metabolic process GO:0051253 262 0.026
rrna metabolic process GO:0016072 244 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.026
gtp metabolic process GO:0046039 107 0.026
lipid modification GO:0030258 37 0.026
regulation of cell division GO:0051302 113 0.026
positive regulation of organelle organization GO:0010638 85 0.026
glycosylation GO:0070085 66 0.026
cellular nitrogen compound catabolic process GO:0044270 494 0.025
cellular response to nutrient levels GO:0031669 144 0.025
organic acid catabolic process GO:0016054 71 0.025
response to chemical GO:0042221 390 0.025
purine nucleotide metabolic process GO:0006163 376 0.025
single organism membrane fusion GO:0044801 71 0.025
ribonucleoside triphosphate catabolic process GO:0009203 327 0.025
negative regulation of macromolecule metabolic process GO:0010605 375 0.025
Mouse
cellular amino acid catabolic process GO:0009063 48 0.025
organophosphate catabolic process GO:0046434 338 0.024
dna replication GO:0006260 147 0.024
carboxylic acid transport GO:0046942 74 0.024
protein modification by small protein conjugation or removal GO:0070647 172 0.024
nucleoside monophosphate metabolic process GO:0009123 267 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.024
nucleic acid transport GO:0050657 94 0.024
cellular amine metabolic process GO:0044106 51 0.023
negative regulation of intracellular signal transduction GO:1902532 27 0.023
Mouse
nitrogen compound transport GO:0071705 212 0.023
cellular response to external stimulus GO:0071496 150 0.023
purine nucleoside triphosphate metabolic process GO:0009144 356 0.023
endomembrane system organization GO:0010256 74 0.023
inorganic ion transmembrane transport GO:0098660 109 0.023
negative regulation of rna biosynthetic process GO:1902679 260 0.023
actin cytoskeleton organization GO:0030036 100 0.022
cytokinetic process GO:0032506 78 0.022
rna localization GO:0006403 112 0.022
regulation of molecular function GO:0065009 320 0.022
Mouse
heterocycle catabolic process GO:0046700 494 0.022
ribonucleotide catabolic process GO:0009261 327 0.022
disaccharide metabolic process GO:0005984 25 0.021
regulation of filamentous growth GO:0010570 38 0.021
establishment or maintenance of cell polarity GO:0007163 96 0.021
nucleoside phosphate catabolic process GO:1901292 331 0.021
positive regulation of gtpase activity GO:0043547 80 0.021
establishment of cell polarity GO:0030010 64 0.021
nucleoside monophosphate catabolic process GO:0009125 224 0.021
ribonucleoside monophosphate catabolic process GO:0009158 224 0.021
purine nucleoside monophosphate catabolic process GO:0009128 224 0.021
regulation of translation GO:0006417 89 0.021
organelle fusion GO:0048284 85 0.020
regulation of cellular component size GO:0032535 50 0.020
purine nucleoside catabolic process GO:0006152 330 0.020
purine ribonucleoside catabolic process GO:0046130 330 0.020
monocarboxylic acid metabolic process GO:0032787 122 0.020
plasma membrane organization GO:0007009 21 0.020
gtp catabolic process GO:0006184 107 0.020
glycosyl compound catabolic process GO:1901658 335 0.020
cellular glucan metabolic process GO:0006073 44 0.019
regulation of cellular protein metabolic process GO:0032268 232 0.019
Mouse
cytoskeleton organization GO:0007010 230 0.019
alpha amino acid metabolic process GO:1901605 124 0.019
oxidation reduction process GO:0055114 353 0.019
nucleoside triphosphate catabolic process GO:0009143 329 0.019
mitotic cytokinesis GO:0000281 58 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.019
cellular carbohydrate metabolic process GO:0044262 135 0.019
microtubule cytoskeleton organization GO:0000226 109 0.019
positive regulation of phosphorus metabolic process GO:0010562 147 0.019
energy derivation by oxidation of organic compounds GO:0015980 125 0.018
guanosine containing compound metabolic process GO:1901068 111 0.018
protein catabolic process GO:0030163 221 0.018
regulation of cellular amine metabolic process GO:0033238 21 0.018
nucleobase containing small molecule metabolic process GO:0055086 491 0.018
microtubule based process GO:0007017 117 0.018
regulation of localization GO:0032879 127 0.018
purine nucleoside triphosphate catabolic process GO:0009146 329 0.018
ribonucleoside catabolic process GO:0042454 332 0.018
negative regulation of catabolic process GO:0009895 43 0.018
negative regulation of nucleic acid templated transcription GO:1903507 260 0.018
anatomical structure development GO:0048856 160 0.018
Mouse
regulation of nuclear division GO:0051783 103 0.018
carbon catabolite regulation of transcription GO:0045990 39 0.018
maintenance of location GO:0051235 66 0.018
Mouse
detection of chemical stimulus GO:0009593 3 0.017
purine ribonucleoside metabolic process GO:0046128 380 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.017
positive regulation of cell death GO:0010942 3 0.017
peptidyl amino acid modification GO:0018193 116 0.017
cell cycle g2 m phase transition GO:0044839 39 0.017
posttranscriptional regulation of gene expression GO:0010608 115 0.017
response to salt stress GO:0009651 34 0.017
nucleotide catabolic process GO:0009166 330 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.016
regulation of anatomical structure size GO:0090066 50 0.016
organelle localization GO:0051640 128 0.016
positive regulation of cellular component biogenesis GO:0044089 45 0.016
trna metabolic process GO:0006399 151 0.016
cellular macromolecule catabolic process GO:0044265 363 0.016
positive regulation of cytoskeleton organization GO:0051495 39 0.016
protein acylation GO:0043543 66 0.016
chromosome segregation GO:0007059 159 0.016
atp catabolic process GO:0006200 224 0.016
ribose phosphate metabolic process GO:0019693 384 0.015
metal ion transport GO:0030001 75 0.015
negative regulation of phosphate metabolic process GO:0045936 49 0.015
Mouse
ribosome assembly GO:0042255 57 0.015
exocytosis GO:0006887 42 0.015
amine metabolic process GO:0009308 51 0.015
regulation of meiotic cell cycle GO:0051445 43 0.015
peroxisome degradation GO:0030242 22 0.015
glucan metabolic process GO:0044042 44 0.015
intra golgi vesicle mediated transport GO:0006891 22 0.015
purine ribonucleotide metabolic process GO:0009150 372 0.015
meiotic nuclear division GO:0007126 163 0.015
sexual reproduction GO:0019953 216 0.015
positive regulation of protein polymerization GO:0032273 22 0.014
cellular component disassembly GO:0022411 86 0.014
regulation of protein modification process GO:0031399 110 0.014
Mouse
aromatic compound catabolic process GO:0019439 491 0.014
ion homeostasis GO:0050801 118 0.014
spindle localization GO:0051653 14 0.014
positive regulation of protein complex assembly GO:0031334 39 0.014
vesicle fusion GO:0006906 33 0.014
positive regulation of transport GO:0051050 32 0.014
negative regulation of nuclear division GO:0051784 62 0.014
regulation of mitosis GO:0007088 65 0.014
positive regulation of rna biosynthetic process GO:1902680 286 0.014
phosphatidylinositol metabolic process GO:0046488 62 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.014
nucleoside catabolic process GO:0009164 335 0.014
actin filament bundle organization GO:0061572 19 0.014
cellular response to abiotic stimulus GO:0071214 62 0.014
regulation of catabolic process GO:0009894 199 0.014
trna processing GO:0008033 101 0.014
invasive filamentous growth GO:0036267 65 0.014
regulation of phosphorus metabolic process GO:0051174 230 0.014
Mouse
g2 m transition of mitotic cell cycle GO:0000086 38 0.014
positive regulation of ras protein signal transduction GO:0046579 3 0.013
negative regulation of mitotic cell cycle GO:0045930 63 0.013
ribonucleoprotein complex subunit organization GO:0071826 152 0.013
purine containing compound catabolic process GO:0072523 332 0.013
regulation of chromosome organization GO:0033044 66 0.013
rna transport GO:0050658 92 0.013
macromolecular complex disassembly GO:0032984 80 0.013
spore wall biogenesis GO:0070590 52 0.013
macroautophagy GO:0016236 55 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
positive regulation of intracellular transport GO:0032388 4 0.013
ascospore type prospore assembly GO:0031321 15 0.013
spore wall assembly GO:0042244 52 0.013
macromolecule glycosylation GO:0043413 57 0.013
cellular modified amino acid metabolic process GO:0006575 51 0.013
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.013
oligosaccharide metabolic process GO:0009311 35 0.013
regulation of transmembrane transporter activity GO:0022898 1 0.013
negative regulation of transcription from rna polymerase ii promoter by pheromones GO:0046020 10 0.012
response to inorganic substance GO:0010035 47 0.012
response to calcium ion GO:0051592 1 0.012
beta glucan biosynthetic process GO:0051274 12 0.012
nucleoside metabolic process GO:0009116 394 0.012
positive regulation of programmed cell death GO:0043068 3 0.012
regulation of protein processing GO:0070613 34 0.012
Mouse
cellular carbohydrate biosynthetic process GO:0034637 49 0.012
positive regulation of cytoplasmic transport GO:1903651 4 0.012
regulation of ras protein signal transduction GO:0046578 47 0.012
response to abiotic stimulus GO:0009628 159 0.012
protein alkylation GO:0008213 48 0.012
response to organic cyclic compound GO:0014070 1 0.012
positive regulation of nucleic acid templated transcription GO:1903508 286 0.012
methylation GO:0032259 101 0.012
divalent metal ion transport GO:0070838 17 0.012
alpha amino acid biosynthetic process GO:1901607 91 0.012
cellular response to pheromone GO:0071444 88 0.012
positive regulation of transcription dna templated GO:0045893 286 0.012
endoplasmic reticulum organization GO:0007029 30 0.012
positive regulation of cellular biosynthetic process GO:0031328 336 0.012
protein glycosylation GO:0006486 57 0.012
cellular response to osmotic stress GO:0071470 50 0.012
regulation of cellular ketone metabolic process GO:0010565 42 0.012
response to starvation GO:0042594 96 0.012
regulation of small gtpase mediated signal transduction GO:0051056 47 0.012
regulation of actin cytoskeleton organization GO:0032956 31 0.012
response to metal ion GO:0010038 24 0.012
regulation of protein metabolic process GO:0051246 237 0.012
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.012
ascospore wall assembly GO:0030476 52 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.012
establishment of rna localization GO:0051236 92 0.012
mitotic cytokinesis site selection GO:1902408 35 0.011
regulation of cellular component biogenesis GO:0044087 112 0.011
Mouse
cellular response to chemical stimulus GO:0070887 315 0.011
double strand break repair via nonhomologous end joining GO:0006303 27 0.011
positive regulation of endocytosis GO:0045807 12 0.011
regulation of cytoskeleton organization GO:0051493 63 0.011
cellular ketone metabolic process GO:0042180 63 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.011
protein complex disassembly GO:0043241 70 0.011
cytokinesis site selection GO:0007105 40 0.011
proton transport GO:0015992 61 0.011
negative regulation of molecular function GO:0044092 68 0.011
Mouse
cellular response to starvation GO:0009267 90 0.011
anion transmembrane transport GO:0098656 79 0.011
positive regulation of receptor mediated endocytosis GO:0048260 4 0.011
glutamine family amino acid catabolic process GO:0009065 13 0.011
positive regulation of nucleoside metabolic process GO:0045979 97 0.011
ribonucleoside triphosphate metabolic process GO:0009199 356 0.011
positive regulation of rna metabolic process GO:0051254 294 0.011
protein acetylation GO:0006473 59 0.011
dna integrity checkpoint GO:0031570 41 0.011
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.011
macromolecule methylation GO:0043414 85 0.011
reactive oxygen species metabolic process GO:0072593 10 0.011
cell cell adhesion GO:0098609 4 0.011
rna modification GO:0009451 99 0.011
chromatin silencing at telomere GO:0006348 84 0.011
regulation of dna templated transcription elongation GO:0032784 44 0.010
actin filament bundle assembly GO:0051017 19 0.010
positive regulation of intracellular protein transport GO:0090316 3 0.010
protein modification by small protein conjugation GO:0032446 144 0.010
response to toxic substance GO:0009636 9 0.010
phosphorylation GO:0016310 291 0.010
Mouse
regulation of catalytic activity GO:0050790 307 0.010
Mouse
ribonucleoprotein complex assembly GO:0022618 143 0.010
response to hypoxia GO:0001666 4 0.010
membrane budding GO:0006900 22 0.010
reproductive process in single celled organism GO:0022413 145 0.010
cation transport GO:0006812 166 0.010
regulation of chromatin organization GO:1902275 23 0.010
vacuole fusion GO:0097576 40 0.010

PEP1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.010