Saccharomyces cerevisiae

17 known processes

APM2 (YHL019C)

Apm2p

APM2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vacuolar transport GO:0007034 145 0.704
golgi vesicle transport GO:0048193 188 0.583
endosomal transport GO:0016197 86 0.416
vesicle mediated transport GO:0016192 335 0.370
retrograde transport endosome to golgi GO:0042147 33 0.325
single organism membrane organization GO:0044802 275 0.240
Human
protein localization to organelle GO:0033365 337 0.226
establishment of protein localization GO:0045184 367 0.221
protein localization to vacuole GO:0072665 92 0.213
membrane organization GO:0061024 276 0.212
Human
signal transduction GO:0007165 208 0.189
regulation of cellular component organization GO:0051128 334 0.182
Human
endocytosis GO:0006897 90 0.182
cell communication GO:0007154 345 0.173
vesicle organization GO:0016050 68 0.168
single organism catabolic process GO:0044712 619 0.168
negative regulation of gene expression GO:0010629 312 0.166
ubiquitin dependent protein catabolic process GO:0006511 181 0.160
organelle fission GO:0048285 272 0.151
carbohydrate derivative biosynthetic process GO:1901137 181 0.141
lipid metabolic process GO:0006629 269 0.129
membrane budding GO:0006900 22 0.125
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.114
oxoacid metabolic process GO:0043436 351 0.104
single organism cellular localization GO:1902580 375 0.101
Human
protein targeting to vacuole GO:0006623 91 0.099
regulation of signal transduction GO:0009966 114 0.098
organelle fusion GO:0048284 85 0.097
carbohydrate derivative metabolic process GO:1901135 549 0.097
golgi to vacuole transport GO:0006896 23 0.092
proteolysis GO:0006508 268 0.086
anatomical structure formation involved in morphogenesis GO:0048646 136 0.082
regulation of response to stimulus GO:0048583 157 0.080
carboxylic acid transport GO:0046942 74 0.077
nuclear division GO:0000280 263 0.076
carboxylic acid metabolic process GO:0019752 338 0.075
modification dependent macromolecule catabolic process GO:0043632 203 0.075
phospholipid metabolic process GO:0006644 125 0.075
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.074
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.073
regulation of growth GO:0040008 50 0.073
endomembrane system organization GO:0010256 74 0.071
Human
microautophagy GO:0016237 43 0.070
negative regulation of rna metabolic process GO:0051253 262 0.069
regulation of receptor mediated endocytosis GO:0048259 4 0.068
negative regulation of cellular metabolic process GO:0031324 407 0.067
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.067
cell differentiation GO:0030154 161 0.067
establishment of protein localization to vacuole GO:0072666 91 0.066
intracellular signal transduction GO:0035556 112 0.064
cellular protein catabolic process GO:0044257 213 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.063
negative regulation of macromolecule metabolic process GO:0010605 375 0.063
regulation of cellular localization GO:0060341 50 0.062
Human
reproduction of a single celled organism GO:0032505 191 0.062
negative regulation of transcription dna templated GO:0045892 258 0.062
late endosome to vacuole transport GO:0045324 42 0.061
negative regulation of rna biosynthetic process GO:1902679 260 0.061
regulation of vesicle mediated transport GO:0060627 39 0.058
membrane invagination GO:0010324 43 0.058
cellular response to starvation GO:0009267 90 0.055
purine nucleoside catabolic process GO:0006152 330 0.054
positive regulation of macromolecule metabolic process GO:0010604 394 0.054
single organism signaling GO:0044700 208 0.054
organophosphate metabolic process GO:0019637 597 0.054
single organism membrane fusion GO:0044801 71 0.053
negative regulation of proteolysis GO:0045861 33 0.053
chemical homeostasis GO:0048878 137 0.053
carboxylic acid biosynthetic process GO:0046394 152 0.053
regulation of biological quality GO:0065008 391 0.053
regulation of protein localization GO:0032880 62 0.052
Human
establishment of protein localization to organelle GO:0072594 278 0.052
nucleophagy GO:0044804 34 0.052
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.051
regulation of signaling GO:0023051 119 0.050
glycerophospholipid metabolic process GO:0006650 98 0.050
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.049
positive regulation of transcription dna templated GO:0045893 286 0.049
positive regulation of nucleic acid templated transcription GO:1903508 286 0.049
ras protein signal transduction GO:0007265 29 0.049
glycosyl compound metabolic process GO:1901657 398 0.048
nucleoside phosphate catabolic process GO:1901292 331 0.048
cellular response to dna damage stimulus GO:0006974 287 0.048
organic acid transport GO:0015849 77 0.047
response to external stimulus GO:0009605 158 0.047
single organism developmental process GO:0044767 258 0.047
intracellular protein transport GO:0006886 319 0.046
cellular cation homeostasis GO:0030003 100 0.046
organonitrogen compound catabolic process GO:1901565 404 0.046
regulation of endocytosis GO:0030100 17 0.046
small gtpase mediated signal transduction GO:0007264 36 0.046
signaling GO:0023052 208 0.045
organic cyclic compound catabolic process GO:1901361 499 0.045
anatomical structure morphogenesis GO:0009653 160 0.045
peroxisome organization GO:0007031 68 0.044
filamentous growth of a population of unicellular organisms GO:0044182 109 0.043
cellular protein complex assembly GO:0043623 209 0.043
protein localization to membrane GO:0072657 102 0.042
Human
glycerolipid metabolic process GO:0046486 108 0.042
positive regulation of cellular biosynthetic process GO:0031328 336 0.042
positive regulation of rna metabolic process GO:0051254 294 0.042
post golgi vesicle mediated transport GO:0006892 72 0.042
cellular ion homeostasis GO:0006873 112 0.041
vacuole fusion GO:0097576 40 0.041
homeostatic process GO:0042592 227 0.041
purine nucleotide metabolic process GO:0006163 376 0.040
organelle assembly GO:0070925 118 0.040
protein transport GO:0015031 345 0.040
protein processing GO:0016485 64 0.039
ion homeostasis GO:0050801 118 0.039
cation transport GO:0006812 166 0.039
regulation of localization GO:0032879 127 0.039
Human
regulation of cell communication GO:0010646 124 0.039
membrane fusion GO:0061025 73 0.039
heterocycle catabolic process GO:0046700 494 0.038
protein modification by small protein conjugation or removal GO:0070647 172 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.037
golgi to endosome transport GO:0006895 17 0.037
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.037
negative regulation of nucleic acid templated transcription GO:1903507 260 0.037
organophosphate catabolic process GO:0046434 338 0.037
modification dependent protein catabolic process GO:0019941 181 0.036
nucleoside triphosphate catabolic process GO:0009143 329 0.036
cellular nitrogen compound catabolic process GO:0044270 494 0.036
protein catabolic process GO:0030163 221 0.035
cellular lipid metabolic process GO:0044255 229 0.035
maintenance of protein location in cell GO:0032507 50 0.035
actin filament based process GO:0030029 104 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.034
nucleoside catabolic process GO:0009164 335 0.034
aromatic compound catabolic process GO:0019439 491 0.033
organic acid metabolic process GO:0006082 352 0.033
nucleotide catabolic process GO:0009166 330 0.033
purine ribonucleoside metabolic process GO:0046128 380 0.033
regulation of cellular protein metabolic process GO:0032268 232 0.032
protein complex assembly GO:0006461 302 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.032
regulation of cellular catabolic process GO:0031329 195 0.032
cellular developmental process GO:0048869 191 0.032
ribonucleoprotein complex subunit organization GO:0071826 152 0.031
single organism membrane invagination GO:1902534 43 0.031
purine ribonucleotide metabolic process GO:0009150 372 0.031
ribose phosphate metabolic process GO:0019693 384 0.031
single organism carbohydrate metabolic process GO:0044723 237 0.031
cellular macromolecule catabolic process GO:0044265 363 0.030
phosphatidylinositol metabolic process GO:0046488 62 0.030
filamentous growth GO:0030447 124 0.030
positive regulation of catabolic process GO:0009896 135 0.030
negative regulation of protein maturation GO:1903318 33 0.030
cvt pathway GO:0032258 37 0.029
actin cytoskeleton organization GO:0030036 100 0.029
negative regulation of cell communication GO:0010648 33 0.029
purine containing compound catabolic process GO:0072523 332 0.029
positive regulation of cellular component organization GO:0051130 116 0.029
ribonucleoside triphosphate metabolic process GO:0009199 356 0.029
regulation of catabolic process GO:0009894 199 0.028
purine ribonucleoside catabolic process GO:0046130 330 0.028
phospholipid biosynthetic process GO:0008654 89 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.028
organonitrogen compound biosynthetic process GO:1901566 314 0.027
establishment of protein localization to membrane GO:0090150 99 0.027
ascospore wall assembly GO:0030476 52 0.027
ion transport GO:0006811 274 0.027
regulation of transport GO:0051049 85 0.027
purine containing compound metabolic process GO:0072521 400 0.027
macromolecule catabolic process GO:0009057 383 0.027
ribonucleotide catabolic process GO:0009261 327 0.026
negative regulation of cellular component organization GO:0051129 109 0.026
Human
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 34 0.026
cellular homeostasis GO:0019725 138 0.026
secretion by cell GO:0032940 50 0.026
growth GO:0040007 157 0.026
cellular component morphogenesis GO:0032989 97 0.026
secretion GO:0046903 50 0.025
carbohydrate metabolic process GO:0005975 252 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.025
purine nucleoside triphosphate catabolic process GO:0009146 329 0.025
nucleotide excision repair GO:0006289 50 0.025
polysaccharide metabolic process GO:0005976 60 0.025
nucleobase containing compound catabolic process GO:0034655 479 0.025
nucleoside phosphate metabolic process GO:0006753 458 0.025
response to organic substance GO:0010033 182 0.024
piecemeal microautophagy of nucleus GO:0034727 33 0.024
carbohydrate derivative catabolic process GO:1901136 339 0.024
ribonucleoside metabolic process GO:0009119 389 0.024
positive regulation of biosynthetic process GO:0009891 336 0.024
small molecule catabolic process GO:0044282 88 0.024
developmental process GO:0032502 261 0.024
regulation of anatomical structure size GO:0090066 50 0.024
reproductive process GO:0022414 248 0.023
regulation of intracellular signal transduction GO:1902531 78 0.023
anatomical structure development GO:0048856 160 0.023
dna replication GO:0006260 147 0.023
lipid biosynthetic process GO:0008610 170 0.023
regulation of protein complex assembly GO:0043254 77 0.023
cellular response to extracellular stimulus GO:0031668 150 0.022
carboxylic acid catabolic process GO:0046395 71 0.022
positive regulation of gtp catabolic process GO:0033126 80 0.022
cellular amino acid catabolic process GO:0009063 48 0.022
protein maturation GO:0051604 76 0.021
purine nucleotide catabolic process GO:0006195 328 0.021
nucleobase containing small molecule metabolic process GO:0055086 491 0.021
cell growth GO:0016049 89 0.021
regulation of cellular component size GO:0032535 50 0.021
protein targeting to membrane GO:0006612 52 0.021
nucleotide metabolic process GO:0009117 453 0.021
positive regulation of endocytosis GO:0045807 12 0.021
posttranscriptional regulation of gene expression GO:0010608 115 0.021
regulation of intracellular transport GO:0032386 26 0.021
cell division GO:0051301 205 0.021
gtp metabolic process GO:0046039 107 0.021
cellular response to external stimulus GO:0071496 150 0.020
cell cycle g2 m phase transition GO:0044839 39 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.020
regulation of protein metabolic process GO:0051246 237 0.020
metal ion transport GO:0030001 75 0.020
negative regulation of cellular biosynthetic process GO:0031327 312 0.019
single organism carbohydrate catabolic process GO:0044724 73 0.019
organelle localization GO:0051640 128 0.019
nucleoside triphosphate metabolic process GO:0009141 364 0.019
nucleoside metabolic process GO:0009116 394 0.019
vacuole organization GO:0007033 75 0.019
protein complex localization GO:0031503 32 0.019
polysaccharide biosynthetic process GO:0000271 39 0.019
purine ribonucleotide catabolic process GO:0009154 327 0.019
purine nucleoside monophosphate metabolic process GO:0009126 262 0.019
positive regulation of cellular catabolic process GO:0031331 128 0.019
rrna processing GO:0006364 227 0.018
vacuole fusion non autophagic GO:0042144 40 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.018
maintenance of location in cell GO:0051651 58 0.018
ascospore wall biogenesis GO:0070591 52 0.018
guanosine containing compound metabolic process GO:1901068 111 0.018
developmental process involved in reproduction GO:0003006 159 0.018
cellular amino acid metabolic process GO:0006520 225 0.018
establishment of organelle localization GO:0051656 96 0.018
cell cycle checkpoint GO:0000075 82 0.018
protein modification by small protein conjugation GO:0032446 144 0.018
maintenance of protein location GO:0045185 53 0.017
ribonucleoprotein complex assembly GO:0022618 143 0.017
purine nucleoside metabolic process GO:0042278 380 0.017
response to starvation GO:0042594 96 0.017
regulation of organelle organization GO:0033043 243 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.017
regulation of ras protein signal transduction GO:0046578 47 0.017
regulation of dna templated transcription in response to stress GO:0043620 51 0.017
mitotic cell cycle phase transition GO:0044772 141 0.017
regulation of hydrolase activity GO:0051336 133 0.017
negative regulation of response to stimulus GO:0048585 40 0.017
regulation of polysaccharide metabolic process GO:0032881 15 0.017
positive regulation of protein metabolic process GO:0051247 93 0.017
positive regulation of cytoplasmic transport GO:1903651 4 0.017
negative regulation of signal transduction GO:0009968 30 0.017
response to nutrient GO:0007584 52 0.017
organic anion transport GO:0015711 114 0.017
ribonucleotide metabolic process GO:0009259 377 0.017
regulation of homeostatic process GO:0032844 19 0.016
multi organism process GO:0051704 233 0.016
macromolecular complex disassembly GO:0032984 80 0.016
regulation of protein maturation GO:1903317 34 0.016
negative regulation of biosynthetic process GO:0009890 312 0.016
carbohydrate catabolic process GO:0016052 77 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.016
regulation of gtpase activity GO:0043087 84 0.016
ribonucleoside triphosphate catabolic process GO:0009203 327 0.016
glycosyl compound catabolic process GO:1901658 335 0.016
single organism membrane budding GO:1902591 21 0.016
sexual reproduction GO:0019953 216 0.016
spindle checkpoint GO:0031577 35 0.016
cell development GO:0048468 107 0.016
cell budding GO:0007114 48 0.016
proteasomal protein catabolic process GO:0010498 141 0.015
positive regulation of intracellular transport GO:0032388 4 0.015
mitotic nuclear division GO:0007067 131 0.015
positive regulation of gtpase activity GO:0043547 80 0.015
er to golgi vesicle mediated transport GO:0006888 86 0.015
dna repair GO:0006281 236 0.015
early endosome to golgi transport GO:0034498 11 0.015
alpha amino acid biosynthetic process GO:1901607 91 0.015
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.015
protein targeting GO:0006605 272 0.015
response to chemical GO:0042221 390 0.015
mitotic cell cycle GO:0000278 306 0.015
negative regulation of protein catabolic process GO:0042177 27 0.015
cell cycle phase transition GO:0044770 144 0.015
cellular protein complex disassembly GO:0043624 42 0.015
protein complex biogenesis GO:0070271 314 0.015
regulation of nucleotide metabolic process GO:0006140 110 0.015
phosphorylation GO:0016310 291 0.014
glycerolipid biosynthetic process GO:0045017 71 0.014
regulation of phosphate metabolic process GO:0019220 230 0.014
mitotic cell cycle process GO:1903047 294 0.014
ascospore formation GO:0030437 107 0.014
cellular response to organic substance GO:0071310 159 0.014
sporulation GO:0043934 132 0.014
ribonucleoside catabolic process GO:0042454 332 0.014
regulation of metal ion transport GO:0010959 2 0.014
protein phosphorylation GO:0006468 197 0.014
cytoskeleton organization GO:0007010 230 0.014
lipid modification GO:0030258 37 0.014
early endosome to late endosome transport GO:0045022 1 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.013
negative regulation of organelle organization GO:0010639 103 0.013
negative regulation of cellular protein catabolic process GO:1903363 27 0.013
response to uv GO:0009411 4 0.013
regulation of ras gtpase activity GO:0032318 41 0.013
chromatin silencing GO:0006342 147 0.013
cellular ketone metabolic process GO:0042180 63 0.013
cellular response to nutrient levels GO:0031669 144 0.013
mitotic cytokinetic process GO:1902410 45 0.013
ribonucleoside monophosphate metabolic process GO:0009161 265 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 36 0.013
cellular component assembly involved in morphogenesis GO:0010927 73 0.013
regulation of dna metabolic process GO:0051052 100 0.013
regulation of chromosome organization GO:0033044 66 0.013
ribonucleoside monophosphate catabolic process GO:0009158 224 0.013
nucleoside monophosphate metabolic process GO:0009123 267 0.013
positive regulation of programmed cell death GO:0043068 3 0.013
dephosphorylation GO:0016311 127 0.013
dna dependent dna replication GO:0006261 115 0.013
atp metabolic process GO:0046034 251 0.013
negative regulation of protein processing GO:0010955 33 0.013
exocytosis GO:0006887 42 0.013
atp catabolic process GO:0006200 224 0.013
regulation of dna replication GO:0006275 51 0.013
cellular component disassembly GO:0022411 86 0.013
actin filament organization GO:0007015 56 0.013
positive regulation of cellular protein metabolic process GO:0032270 89 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.013
regulation of dna dependent dna replication GO:0090329 37 0.012
meiotic nuclear division GO:0007126 163 0.012
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.012
regulation of purine nucleotide catabolic process GO:0033121 106 0.012
pseudohyphal growth GO:0007124 75 0.012
positive regulation of intracellular protein transport GO:0090316 3 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.012
alpha amino acid metabolic process GO:1901605 124 0.012
regulation of cell cycle GO:0051726 195 0.012
protein modification by small protein removal GO:0070646 29 0.012
negative regulation of signaling GO:0023057 30 0.012
regulation of cellular ketone metabolic process GO:0010565 42 0.012
protein localization to plasma membrane GO:0072659 18 0.012
Human
reproductive process in single celled organism GO:0022413 145 0.012
fungal type cell wall organization or biogenesis GO:0071852 169 0.012
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.012
protein localization to golgi apparatus GO:0034067 13 0.012
cellular response to oxidative stress GO:0034599 94 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
negative regulation of cell cycle GO:0045786 91 0.012
phospholipid dephosphorylation GO:0046839 15 0.012
regulation of molecular function GO:0065009 320 0.012
regulation of nucleoside metabolic process GO:0009118 106 0.012
methylation GO:0032259 101 0.012
trna aminoacylation for protein translation GO:0006418 32 0.012
cellular amine metabolic process GO:0044106 51 0.012
maintenance of location GO:0051235 66 0.011
regulation of purine nucleotide metabolic process GO:1900542 109 0.011
regulation of establishment of protein localization GO:0070201 17 0.011
translation GO:0006412 230 0.011
mrna catabolic process GO:0006402 93 0.011
chromatin remodeling GO:0006338 80 0.011
response to oxygen containing compound GO:1901700 61 0.011
regulation of phosphorus metabolic process GO:0051174 230 0.011
cation homeostasis GO:0055080 105 0.011
regulation of nucleotide catabolic process GO:0030811 106 0.011
regulation of mitosis GO:0007088 65 0.011
monocarboxylic acid catabolic process GO:0072329 26 0.011
protein polyubiquitination GO:0000209 20 0.011
mitochondrion organization GO:0007005 261 0.011
positive regulation of catalytic activity GO:0043085 178 0.011
protein complex disassembly GO:0043241 70 0.011
amine metabolic process GO:0009308 51 0.011
negative regulation of cellular catabolic process GO:0031330 43 0.011
cell wall biogenesis GO:0042546 93 0.011
phosphatidylinositol biosynthetic process GO:0006661 39 0.011
cellular response to chemical stimulus GO:0070887 315 0.011
fungal type cell wall assembly GO:0071940 53 0.011
regulation of ph GO:0006885 21 0.011
cell surface receptor signaling pathway GO:0007166 38 0.011
metal ion homeostasis GO:0055065 79 0.011
mitochondrial genome maintenance GO:0000002 40 0.011
glucan metabolic process GO:0044042 44 0.011
organic acid catabolic process GO:0016054 71 0.011
cellular metal ion homeostasis GO:0006875 78 0.010
response to organic cyclic compound GO:0014070 1 0.010
positive regulation of cell death GO:0010942 3 0.010
plasma membrane organization GO:0007009 21 0.010
Human
regulation of lipid catabolic process GO:0050994 4 0.010
positive regulation of gene expression GO:0010628 321 0.010
intralumenal vesicle formation GO:0070676 7 0.010
macroautophagy GO:0016236 55 0.010

APM2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
disease of anatomical entity DOID:7 0 0.011