Saccharomyces cerevisiae

60 known processes

HRB1 (YNL004W)

Hrb1p

(Aliases: TOM34)

HRB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.216
Yeast
oxoacid metabolic process GO:0043436 351 0.200
nuclear transport GO:0051169 165 0.183
small molecule biosynthetic process GO:0044283 258 0.183
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.163
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.159
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.149
Yeast
trna metabolic process GO:0006399 151 0.149
anatomical structure homeostasis GO:0060249 74 0.144
ncrna processing GO:0034470 330 0.141
regulation of biological quality GO:0065008 391 0.132
organic acid metabolic process GO:0006082 352 0.131
lipid biosynthetic process GO:0008610 170 0.131
carboxylic acid biosynthetic process GO:0046394 152 0.128
nucleic acid transport GO:0050657 94 0.127
transcription from rna polymerase i promoter GO:0006360 63 0.120
ribonucleoprotein complex assembly GO:0022618 143 0.120
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.119
Yeast
positive regulation of macromolecule metabolic process GO:0010604 394 0.119
Yeast
positive regulation of gene expression GO:0010628 321 0.104
Yeast
positive regulation of rna biosynthetic process GO:1902680 286 0.100
Yeast
establishment of rna localization GO:0051236 92 0.099
organophosphate metabolic process GO:0019637 597 0.099
phosphorylation GO:0016310 291 0.096
carboxylic acid metabolic process GO:0019752 338 0.092
cellular amino acid metabolic process GO:0006520 225 0.090
peptidyl amino acid modification GO:0018193 116 0.083
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.081
Yeast
rna localization GO:0006403 112 0.078
nucleobase containing compound transport GO:0015931 124 0.078
rna transport GO:0050658 92 0.077
positive regulation of nucleic acid templated transcription GO:1903508 286 0.076
Yeast
cation homeostasis GO:0055080 105 0.076
mrna metabolic process GO:0016071 269 0.075
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.073
Human Yeast
carbohydrate derivative metabolic process GO:1901135 549 0.072
protein phosphorylation GO:0006468 197 0.072
homeostatic process GO:0042592 227 0.070
mrna processing GO:0006397 185 0.069
Human Yeast
nucleoside phosphate metabolic process GO:0006753 458 0.067
nuclear export GO:0051168 124 0.066
lipid metabolic process GO:0006629 269 0.065
alpha amino acid metabolic process GO:1901605 124 0.065
rrna processing GO:0006364 227 0.063
cellular cation homeostasis GO:0030003 100 0.063
telomere organization GO:0032200 75 0.062
positive regulation of biosynthetic process GO:0009891 336 0.061
Yeast
positive regulation of rna metabolic process GO:0051254 294 0.061
Yeast
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.060
translation GO:0006412 230 0.060
Yeast
cellular chemical homeostasis GO:0055082 123 0.060
organonitrogen compound biosynthetic process GO:1901566 314 0.058
positive regulation of cellular biosynthetic process GO:0031328 336 0.058
Yeast
chemical homeostasis GO:0048878 137 0.058
cellular protein complex assembly GO:0043623 209 0.057
dna templated transcription elongation GO:0006354 91 0.057
Yeast
regulation of cellular component organization GO:0051128 334 0.056
Yeast
negative regulation of cellular metabolic process GO:0031324 407 0.054
Human Yeast
glycosyl compound metabolic process GO:1901657 398 0.053
nuclear mrna surveillance GO:0071028 22 0.051
positive regulation of transcription from rna polymerase i promoter GO:0045943 19 0.051
mitotic cell cycle GO:0000278 306 0.050
Fly
mrna splicing via spliceosome GO:0000398 108 0.050
Human Yeast
cellular homeostasis GO:0019725 138 0.050
nucleobase containing compound catabolic process GO:0034655 479 0.049
sterol transport GO:0015918 24 0.048
organic cyclic compound catabolic process GO:1901361 499 0.048
monocarboxylic acid metabolic process GO:0032787 122 0.047
single organism catabolic process GO:0044712 619 0.047
cellular amino acid biosynthetic process GO:0008652 118 0.046
transcription elongation from rna polymerase i promoter GO:0006362 10 0.046
aromatic compound catabolic process GO:0019439 491 0.045
trna processing GO:0008033 101 0.044
dna templated transcription initiation GO:0006352 71 0.044
response to chemical GO:0042221 390 0.044
transcription from rna polymerase iii promoter GO:0006383 40 0.044
alpha amino acid biosynthetic process GO:1901607 91 0.043
coenzyme metabolic process GO:0006732 104 0.043
organic acid biosynthetic process GO:0016053 152 0.042
chromatin modification GO:0016568 200 0.042
positive regulation of transcription dna templated GO:0045893 286 0.042
Yeast
methylation GO:0032259 101 0.040
cellular metal ion homeostasis GO:0006875 78 0.040
macromolecular complex disassembly GO:0032984 80 0.040
Yeast
filamentous growth GO:0030447 124 0.040
nucleobase containing small molecule metabolic process GO:0055086 491 0.038
ion homeostasis GO:0050801 118 0.037
negative regulation of biosynthetic process GO:0009890 312 0.037
Yeast
signal transduction GO:0007165 208 0.037
rna export from nucleus GO:0006405 88 0.035
nucleus organization GO:0006997 62 0.035
protein catabolic process GO:0030163 221 0.035
mrna transport GO:0051028 60 0.035
ribonucleoside metabolic process GO:0009119 389 0.034
phosphorylation of rna polymerase ii c terminal domain GO:0070816 20 0.034
reproduction of a single celled organism GO:0032505 191 0.034
invasive growth in response to glucose limitation GO:0001403 61 0.034
ribosome biogenesis GO:0042254 335 0.034
purine nucleoside triphosphate metabolic process GO:0009144 356 0.033
phospholipid metabolic process GO:0006644 125 0.033
nitrogen compound transport GO:0071705 212 0.033
regulation of catabolic process GO:0009894 199 0.033
ncrna 3 end processing GO:0043628 44 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.033
rna surveillance GO:0071025 30 0.033
intracellular signal transduction GO:0035556 112 0.032
nucleoside metabolic process GO:0009116 394 0.032
rrna metabolic process GO:0016072 244 0.031
macromolecule methylation GO:0043414 85 0.031
developmental process involved in reproduction GO:0003006 159 0.031
multi organism cellular process GO:0044764 120 0.031
ribonucleoprotein complex subunit organization GO:0071826 152 0.031
Human
purine containing compound metabolic process GO:0072521 400 0.031
regulation of response to stress GO:0080134 57 0.031
nucleotide metabolic process GO:0009117 453 0.030
mrna export from nucleus GO:0006406 60 0.030
negative regulation of dna metabolic process GO:0051053 36 0.029
amine metabolic process GO:0009308 51 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.029
Yeast
negative regulation of rna biosynthetic process GO:1902679 260 0.029
Yeast
negative regulation of transcription dna templated GO:0045892 258 0.029
Yeast
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.028
Yeast
cellular response to dna damage stimulus GO:0006974 287 0.028
Fly
carbohydrate derivative catabolic process GO:1901136 339 0.028
cellular ion homeostasis GO:0006873 112 0.028
phospholipid biosynthetic process GO:0008654 89 0.027
lipid localization GO:0010876 60 0.027
cellular response to chemical stimulus GO:0070887 315 0.027
snorna metabolic process GO:0016074 40 0.027
ribosomal large subunit biogenesis GO:0042273 98 0.027
regulation of mitotic cell cycle GO:0007346 107 0.026
Fly
regulation of localization GO:0032879 127 0.026
negative regulation of macromolecule metabolic process GO:0010605 375 0.026
Human Yeast
transcription coupled nucleotide excision repair GO:0006283 16 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.026
Human Yeast
negative regulation of cellular biosynthetic process GO:0031327 312 0.026
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.026
Human Yeast
lipid transport GO:0006869 58 0.025
regulation of cellular component size GO:0032535 50 0.025
regulation of protein metabolic process GO:0051246 237 0.025
Yeast
dna repair GO:0006281 236 0.025
histone h3 k4 methylation GO:0051568 18 0.025
regulation of cell cycle GO:0051726 195 0.025
Fly
regulation of response to dna damage stimulus GO:2001020 17 0.025
ion transport GO:0006811 274 0.025
purine ribonucleoside metabolic process GO:0046128 380 0.024
invasive filamentous growth GO:0036267 65 0.024
response to temperature stimulus GO:0009266 74 0.024
protein modification by small protein conjugation GO:0032446 144 0.024
dna recombination GO:0006310 172 0.024
gtp metabolic process GO:0046039 107 0.024
gtp catabolic process GO:0006184 107 0.024
glycosyl compound catabolic process GO:1901658 335 0.024
nucleoside triphosphate catabolic process GO:0009143 329 0.024
cellular ketone metabolic process GO:0042180 63 0.024
regulation of cellular amino acid metabolic process GO:0006521 16 0.024
heterocycle catabolic process GO:0046700 494 0.024
cellular protein catabolic process GO:0044257 213 0.023
nucleocytoplasmic transport GO:0006913 163 0.023
purine ribonucleotide metabolic process GO:0009150 372 0.023
regulation of response to stimulus GO:0048583 157 0.023
cellular lipid metabolic process GO:0044255 229 0.023
cytoplasmic translation GO:0002181 65 0.023
regulation of dna metabolic process GO:0051052 100 0.023
ribonucleotide catabolic process GO:0009261 327 0.023
phosphatidylinositol metabolic process GO:0046488 62 0.022
organic hydroxy compound transport GO:0015850 41 0.022
reproductive process in single celled organism GO:0022413 145 0.022
cellular response to organic substance GO:0071310 159 0.022
purine ribonucleotide catabolic process GO:0009154 327 0.022
nucleoside triphosphate metabolic process GO:0009141 364 0.022
rna splicing via transesterification reactions GO:0000375 118 0.022
Human Yeast
regulation of multi organism process GO:0043900 20 0.022
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.022
Yeast
purine containing compound catabolic process GO:0072523 332 0.022
organophosphate biosynthetic process GO:0090407 182 0.021
positive regulation of cytoplasmic transport GO:1903651 4 0.021
regulation of mitosis GO:0007088 65 0.021
protein localization to organelle GO:0033365 337 0.020
single organism reproductive process GO:0044702 159 0.020
carbohydrate biosynthetic process GO:0016051 82 0.020
covalent chromatin modification GO:0016569 119 0.020
purine nucleoside catabolic process GO:0006152 330 0.020
regulation of transcription coupled nucleotide excision repair GO:0090262 7 0.019
positive regulation of intracellular protein transport GO:0090316 3 0.019
cellular nitrogen compound catabolic process GO:0044270 494 0.019
organelle fission GO:0048285 272 0.019
protein modification by small protein conjugation or removal GO:0070647 172 0.019
positive regulation of apoptotic process GO:0043065 3 0.019
transmembrane transport GO:0055085 349 0.019
regulation of phosphate metabolic process GO:0019220 230 0.019
cellular modified amino acid metabolic process GO:0006575 51 0.019
single organism carbohydrate metabolic process GO:0044723 237 0.019
multi organism process GO:0051704 233 0.018
organophosphate ester transport GO:0015748 45 0.018
filamentous growth of a population of unicellular organisms GO:0044182 109 0.018
nucleotide catabolic process GO:0009166 330 0.018
mitochondrial transport GO:0006839 76 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.018
protein complex biogenesis GO:0070271 314 0.018
cofactor metabolic process GO:0051186 126 0.018
regulation of protein localization GO:0032880 62 0.018
positive regulation of cellular component organization GO:0051130 116 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.018
Yeast
regulation of cellular catabolic process GO:0031329 195 0.018
establishment of protein localization to organelle GO:0072594 278 0.018
organophosphate catabolic process GO:0046434 338 0.018
protein import GO:0017038 122 0.018
purine nucleoside metabolic process GO:0042278 380 0.018
cellular amine metabolic process GO:0044106 51 0.017
mitotic recombination GO:0006312 55 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.017
trna wobble base modification GO:0002097 27 0.017
single organism membrane organization GO:0044802 275 0.017
protein localization to membrane GO:0072657 102 0.017
regulation of cellular ketone metabolic process GO:0010565 42 0.017
response to organic cyclic compound GO:0014070 1 0.017
cell fate commitment GO:0045165 32 0.017
regulation of cellular amine metabolic process GO:0033238 21 0.017
positive regulation of organelle organization GO:0010638 85 0.017
pseudohyphal growth GO:0007124 75 0.017
positive regulation of transport GO:0051050 32 0.017
response to organic substance GO:0010033 182 0.017
protein complex disassembly GO:0043241 70 0.017
Yeast
developmental process GO:0032502 261 0.017
Mouse Fly
regulation of ras gtpase activity GO:0032318 41 0.017
cellular amide metabolic process GO:0043603 59 0.017
cellular macromolecule catabolic process GO:0044265 363 0.016
positive regulation of phosphorus metabolic process GO:0010562 147 0.016
negative regulation of rna metabolic process GO:0051253 262 0.016
Human Yeast
positive regulation of programmed cell death GO:0043068 3 0.016
nucleoside catabolic process GO:0009164 335 0.016
regulation of translation GO:0006417 89 0.016
Yeast
negative regulation of nucleic acid templated transcription GO:1903507 260 0.016
Yeast
regulation of chromosome organization GO:0033044 66 0.016
guanosine containing compound metabolic process GO:1901068 111 0.016
response to hypoxia GO:0001666 4 0.016
regulation of signaling GO:0023051 119 0.016
ribonucleotide metabolic process GO:0009259 377 0.016
regulation of anatomical structure size GO:0090066 50 0.016
maturation of 5 8s rrna GO:0000460 80 0.016
histone methylation GO:0016571 28 0.016
regulation of protein phosphorylation GO:0001932 75 0.015
regulation of organelle organization GO:0033043 243 0.015
purine nucleoside triphosphate catabolic process GO:0009146 329 0.015
regulation of cellular protein metabolic process GO:0032268 232 0.015
Yeast
response to osmotic stress GO:0006970 83 0.015
regulation of protein complex assembly GO:0043254 77 0.015
establishment or maintenance of cell polarity GO:0007163 96 0.015
organic hydroxy compound biosynthetic process GO:1901617 81 0.015
positive regulation of secretion by cell GO:1903532 2 0.015
histone ubiquitination GO:0016574 17 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.015
regulation of dna templated transcription elongation GO:0032784 44 0.015
Yeast
negative regulation of chromatin silencing GO:0031936 25 0.015
anatomical structure development GO:0048856 160 0.015
Mouse Fly
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.015
ribonucleoside catabolic process GO:0042454 332 0.015
rna 3 end processing GO:0031123 88 0.015
regulation of protein ubiquitination GO:0031396 20 0.015
regulation of cellular response to stress GO:0080135 50 0.015
regulation of cellular component biogenesis GO:0044087 112 0.015
purine nucleotide catabolic process GO:0006195 328 0.015
regulation of transcription by chromatin organization GO:0034401 19 0.014
rna modification GO:0009451 99 0.014
positive regulation of secretion GO:0051047 2 0.014
reproductive process GO:0022414 248 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.014
protein alkylation GO:0008213 48 0.014
cellular component assembly involved in morphogenesis GO:0010927 73 0.014
cellular response to nutrient GO:0031670 50 0.014
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.014
positive regulation of dna templated transcription elongation GO:0032786 42 0.014
Yeast
guanosine containing compound catabolic process GO:1901069 109 0.014
budding cell apical bud growth GO:0007118 19 0.014
cellular response to pheromone GO:0071444 88 0.014
growth GO:0040007 157 0.014
conjugation GO:0000746 107 0.014
regulation of cellular localization GO:0060341 50 0.014
alcohol biosynthetic process GO:0046165 75 0.014
purine nucleotide metabolic process GO:0006163 376 0.014
response to oxidative stress GO:0006979 99 0.013
regulation of dna dependent dna replication GO:0090329 37 0.013
regulation of microtubule based process GO:0032886 32 0.013
purine ribonucleoside catabolic process GO:0046130 330 0.013
rrna modification GO:0000154 19 0.013
cytoskeleton organization GO:0007010 230 0.013
glycolipid metabolic process GO:0006664 31 0.013
cellular response to hypoxia GO:0071456 4 0.013
cellular component disassembly GO:0022411 86 0.013
Yeast
establishment of organelle localization GO:0051656 96 0.013
regulation of cell communication GO:0010646 124 0.013
ribonucleoside triphosphate catabolic process GO:0009203 327 0.013
organonitrogen compound catabolic process GO:1901565 404 0.013
cellular carbohydrate metabolic process GO:0044262 135 0.013
multi organism reproductive process GO:0044703 216 0.013
glycerolipid metabolic process GO:0046486 108 0.013
regulation of histone methylation GO:0031060 8 0.013
sterol biosynthetic process GO:0016126 35 0.013
regulation of transport GO:0051049 85 0.013
snorna processing GO:0043144 34 0.013
rna splicing GO:0008380 131 0.013
Human Yeast Mouse
regulation of histone ubiquitination GO:0033182 7 0.013
regulation of phosphorus metabolic process GO:0051174 230 0.013
nuclear division GO:0000280 263 0.013
steroid biosynthetic process GO:0006694 35 0.012
establishment of protein localization to membrane GO:0090150 99 0.012
negative regulation of gene expression GO:0010629 312 0.012
Human Yeast
microtubule based process GO:0007017 117 0.012
cellular component morphogenesis GO:0032989 97 0.012
hexose metabolic process GO:0019318 78 0.012
regulation of filamentous growth of a population of unicellular organisms GO:1900428 36 0.012
apoptotic process GO:0006915 30 0.012
single organism signaling GO:0044700 208 0.012
sterol metabolic process GO:0016125 47 0.012
negative regulation of mitotic cell cycle GO:0045930 63 0.012
Fly
positive regulation of cell death GO:0010942 3 0.012
glycerophospholipid metabolic process GO:0006650 98 0.012
ergosterol metabolic process GO:0008204 31 0.012
trna wobble uridine modification GO:0002098 26 0.012
positive regulation of ras gtpase activity GO:0032320 41 0.012
regulation of filamentous growth GO:0010570 38 0.012
response to extracellular stimulus GO:0009991 156 0.012
mitotic nuclear division GO:0007067 131 0.012
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.012
protein depolymerization GO:0051261 21 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.012
Yeast
cellular response to extracellular stimulus GO:0031668 150 0.011
cellular developmental process GO:0048869 191 0.011
Fly
regulation of transcription elongation from rna polymerase i promoter GO:2001207 7 0.011
mrna splice site selection GO:0006376 8 0.011
Human
exit from mitosis GO:0010458 37 0.011
monosaccharide metabolic process GO:0005996 83 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 40 0.011
trna modification GO:0006400 75 0.011
positive regulation of gtpase activity GO:0043547 80 0.011
cell growth GO:0016049 89 0.011
ribonucleoside triphosphate metabolic process GO:0009199 356 0.011
regulation of dna templated transcription in response to stress GO:0043620 51 0.011
purine nucleoside biosynthetic process GO:0042451 31 0.011
regulation of protein modification process GO:0031399 110 0.011
posttranscriptional regulation of gene expression GO:0010608 115 0.011
Yeast
histone lysine methylation GO:0034968 26 0.011
protein methylation GO:0006479 48 0.011
positive regulation of cellular protein metabolic process GO:0032270 89 0.011
cell death GO:0008219 30 0.011
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.011
regulation of nucleotide metabolic process GO:0006140 110 0.011
regulation of dna replication GO:0006275 51 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.011
phosphatidylinositol biosynthetic process GO:0006661 39 0.011
regulation of gtp catabolic process GO:0033124 84 0.011
nucleotide excision repair GO:0006289 50 0.011
mitochondrial translation GO:0032543 52 0.011
positive regulation of nucleoside metabolic process GO:0045979 97 0.011
peptidyl lysine modification GO:0018205 77 0.011
cell aging GO:0007569 70 0.011
proteasome assembly GO:0043248 31 0.011
death GO:0016265 30 0.011
cell differentiation GO:0030154 161 0.011
Fly
positive regulation of intracellular transport GO:0032388 4 0.011
cell development GO:0048468 107 0.011
regulation of dna repair GO:0006282 14 0.011
nuclear transcribed mrna catabolic process GO:0000956 89 0.011
replicative cell aging GO:0001302 46 0.011
nucleoside phosphate catabolic process GO:1901292 331 0.011
alcohol metabolic process GO:0006066 112 0.011
regulation of intracellular transport GO:0032386 26 0.011
positive regulation of cellular catabolic process GO:0031331 128 0.010
ribose phosphate metabolic process GO:0019693 384 0.010
positive regulation of phosphate metabolic process GO:0045937 147 0.010
response to heat GO:0009408 69 0.010
cell communication GO:0007154 345 0.010
mrna catabolic process GO:0006402 93 0.010
regulation of purine nucleotide metabolic process GO:1900542 109 0.010
organic hydroxy compound metabolic process GO:1901615 125 0.010
negative regulation of gene expression epigenetic GO:0045814 147 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.010
cell surface receptor signaling pathway GO:0007166 38 0.010
metal ion homeostasis GO:0055065 79 0.010
monovalent inorganic cation transport GO:0015672 78 0.010
recombinational repair GO:0000725 64 0.010
positive regulation of nucleotide metabolic process GO:0045981 101 0.010
signaling GO:0023052 208 0.010

HRB1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011