Saccharomyces cerevisiae

38 known processes

MDN1 (YLR106C)

Mdn1p

(Aliases: REA1)

MDN1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribosomal large subunit biogenesis GO:0042273 98 0.820
protein dna complex subunit organization GO:0071824 153 0.540
ribosome biogenesis GO:0042254 335 0.506
nuclear dna replication GO:0033260 27 0.465
proteolysis GO:0006508 268 0.463
dna replication initiation GO:0006270 48 0.430
organelle localization GO:0051640 128 0.425
dna dependent dna replication GO:0006261 115 0.413
rrna processing GO:0006364 227 0.404
regulation of dna metabolic process GO:0051052 100 0.378
regulation of dna dependent dna replication initiation GO:0030174 21 0.353
cell cycle dna replication GO:0044786 36 0.263
pre replicative complex assembly GO:0036388 20 0.252
pre replicative complex assembly involved in nuclear cell cycle dna replication GO:0006267 20 0.237
nuclear export GO:0051168 124 0.231
ribosome localization GO:0033750 46 0.226
ribosomal large subunit export from nucleus GO:0000055 27 0.224
regulation of dna dependent dna replication GO:0090329 37 0.220
ribosomal large subunit assembly GO:0000027 35 0.215
ribonucleoprotein complex localization GO:0071166 46 0.182
dna conformation change GO:0071103 98 0.177
establishment of organelle localization GO:0051656 96 0.174
pre replicative complex assembly involved in cell cycle dna replication GO:1902299 20 0.162
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 33 0.160
rrna metabolic process GO:0016072 244 0.158
negative regulation of cellular metabolic process GO:0031324 407 0.154
organelle assembly GO:0070925 118 0.153
chromatin silencing GO:0006342 147 0.151
ribonucleoprotein complex assembly GO:0022618 143 0.150
nucleocytoplasmic transport GO:0006913 163 0.150
lipid metabolic process GO:0006629 269 0.149
ribonucleoprotein complex subunit organization GO:0071826 152 0.141
regulation of biological quality GO:0065008 391 0.139
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.133
protein localization to organelle GO:0033365 337 0.132
vesicle mediated transport GO:0016192 335 0.131
establishment of protein localization GO:0045184 367 0.130
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.127
glycosyl compound biosynthetic process GO:1901659 42 0.124
mitotic cell cycle GO:0000278 306 0.123
negative regulation of nucleic acid templated transcription GO:1903507 260 0.121
regulation of dna replication GO:0006275 51 0.121
carboxylic acid metabolic process GO:0019752 338 0.120
protein ubiquitination GO:0016567 118 0.118
single organism cellular localization GO:1902580 375 0.117
ribosomal subunit export from nucleus GO:0000054 46 0.116
response to chemical GO:0042221 390 0.112
chromatin assembly or disassembly GO:0006333 60 0.111
protein catabolic process GO:0030163 221 0.108
pyrimidine containing compound metabolic process GO:0072527 37 0.107
dna packaging GO:0006323 55 0.105
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.104
negative regulation of rna biosynthetic process GO:1902679 260 0.103
maturation of lsu rrna GO:0000470 39 0.101
dna recombination GO:0006310 172 0.098
nucleotide biosynthetic process GO:0009165 79 0.098
ribonucleoprotein complex export from nucleus GO:0071426 46 0.097
histone modification GO:0016570 119 0.094
chromatin silencing at silent mating type cassette GO:0030466 53 0.093
regulation of gene expression epigenetic GO:0040029 147 0.089
protein import GO:0017038 122 0.089
protein modification by small protein conjugation GO:0032446 144 0.089
nucleobase containing small molecule metabolic process GO:0055086 491 0.086
actin filament based process GO:0030029 104 0.085
organophosphate metabolic process GO:0019637 597 0.085
dna replication GO:0006260 147 0.083
nucleus organization GO:0006997 62 0.083
secretion by cell GO:0032940 50 0.082
chromatin silencing at telomere GO:0006348 84 0.081
endocytosis GO:0006897 90 0.081
protein dna complex assembly GO:0065004 105 0.081
ncrna processing GO:0034470 330 0.080
negative regulation of transcription dna templated GO:0045892 258 0.079
negative regulation of gene expression epigenetic GO:0045814 147 0.078
telomere organization GO:0032200 75 0.076
nuclear transport GO:0051169 165 0.073
ribosome assembly GO:0042255 57 0.073
protein modification by small protein conjugation or removal GO:0070647 172 0.072
single organism nuclear import GO:1902593 56 0.070
sexual sporulation GO:0034293 113 0.070
nucleoside phosphate metabolic process GO:0006753 458 0.070
organic acid metabolic process GO:0006082 352 0.069
establishment of ribosome localization GO:0033753 46 0.065
chromatin assembly GO:0031497 35 0.065
lipid localization GO:0010876 60 0.065
cofactor metabolic process GO:0051186 126 0.063
negative regulation of biosynthetic process GO:0009890 312 0.062
gene silencing GO:0016458 151 0.061
phosphatidylinositol metabolic process GO:0046488 62 0.059
anatomical structure development GO:0048856 160 0.059
nucleosome organization GO:0034728 63 0.058
protein import into nucleus GO:0006606 55 0.056
organophosphate catabolic process GO:0046434 338 0.055
negative regulation of macromolecule metabolic process GO:0010605 375 0.054
developmental process GO:0032502 261 0.054
nucleosome assembly GO:0006334 16 0.052
g1 s transition of mitotic cell cycle GO:0000082 64 0.052
exit from mitosis GO:0010458 37 0.052
regulation of protein metabolic process GO:0051246 237 0.049
regulation of protein maturation GO:1903317 34 0.049
covalent chromatin modification GO:0016569 119 0.049
secretion GO:0046903 50 0.048
regulation of protein ubiquitination GO:0031396 20 0.048
negative regulation of rna metabolic process GO:0051253 262 0.048
negative regulation of gene expression GO:0010629 312 0.047
signaling GO:0023052 208 0.047
cytoskeleton organization GO:0007010 230 0.047
cell cycle g1 s phase transition GO:0044843 64 0.047
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 46 0.046
amino acid activation GO:0043038 35 0.046
mitochondrion organization GO:0007005 261 0.046
cellular response to chemical stimulus GO:0070887 315 0.044
nucleotide metabolic process GO:0009117 453 0.044
regulation of proteolysis GO:0030162 44 0.043
cellular macromolecule catabolic process GO:0044265 363 0.043
purine ribonucleoside catabolic process GO:0046130 330 0.043
anatomical structure morphogenesis GO:0009653 160 0.042
golgi vesicle transport GO:0048193 188 0.042
trna aminoacylation for protein translation GO:0006418 32 0.041
trna aminoacylation GO:0043039 35 0.040
organic hydroxy compound metabolic process GO:1901615 125 0.040
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 80 0.040
maturation of 5 8s rrna GO:0000460 80 0.040
regulation of transcription by chromatin organization GO:0034401 19 0.039
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 19 0.039
gene silencing by rna GO:0031047 3 0.039
reproductive process in single celled organism GO:0022413 145 0.039
oxoacid metabolic process GO:0043436 351 0.038
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.038
small molecule biosynthetic process GO:0044283 258 0.038
transcription of nuclear large rrna transcript from rna polymerase i promoter GO:0042790 19 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.037
regulation of catalytic activity GO:0050790 307 0.037
telomere maintenance GO:0000723 74 0.036
glycosyl compound metabolic process GO:1901657 398 0.036
sporulation resulting in formation of a cellular spore GO:0030435 129 0.036
mrna polyadenylation GO:0006378 20 0.036
carbohydrate derivative biosynthetic process GO:1901137 181 0.036
cellular lipid metabolic process GO:0044255 229 0.036
response to extracellular stimulus GO:0009991 156 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.034
establishment of protein localization to organelle GO:0072594 278 0.033
ribonucleotide catabolic process GO:0009261 327 0.033
cellular developmental process GO:0048869 191 0.033
meiotic cell cycle process GO:1903046 229 0.032
double strand break repair GO:0006302 105 0.032
regulation of cellular protein metabolic process GO:0032268 232 0.032
cellular protein catabolic process GO:0044257 213 0.032
ubiquitin dependent protein catabolic process GO:0006511 181 0.031
protein acylation GO:0043543 66 0.031
cell differentiation GO:0030154 161 0.031
histone acetylation GO:0016573 51 0.030
protein transport GO:0015031 345 0.030
developmental growth GO:0048589 3 0.030
chromatin organization GO:0006325 242 0.029
trna metabolic process GO:0006399 151 0.029
cellular response to endogenous stimulus GO:0071495 22 0.029
glycerolipid metabolic process GO:0046486 108 0.029
sporulation GO:0043934 132 0.029
single organism catabolic process GO:0044712 619 0.029
regulation of exit from mitosis GO:0007096 29 0.029
negative regulation of molecular function GO:0044092 68 0.029
mitotic cell cycle process GO:1903047 294 0.028
histone lysine methylation GO:0034968 26 0.028
purine nucleotide metabolic process GO:0006163 376 0.028
response to abiotic stimulus GO:0009628 159 0.027
negative regulation of cellular biosynthetic process GO:0031327 312 0.027
heterocycle catabolic process GO:0046700 494 0.027
regulation of cell cycle GO:0051726 195 0.027
protein maturation GO:0051604 76 0.027
cofactor biosynthetic process GO:0051188 80 0.027
invasive filamentous growth GO:0036267 65 0.027
glycosyl compound catabolic process GO:1901658 335 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.026
exocytosis GO:0006887 42 0.026
intracellular protein transport GO:0006886 319 0.026
purine nucleotide catabolic process GO:0006195 328 0.026
response to organic cyclic compound GO:0014070 1 0.026
response to nutrient levels GO:0031667 150 0.026
organonitrogen compound catabolic process GO:1901565 404 0.026
ascospore formation GO:0030437 107 0.026
carbohydrate derivative metabolic process GO:1901135 549 0.025
guanosine containing compound metabolic process GO:1901068 111 0.025
purine nucleoside triphosphate catabolic process GO:0009146 329 0.025
internal peptidyl lysine acetylation GO:0018393 52 0.025
nuclear import GO:0051170 57 0.025
protein deubiquitination GO:0016579 17 0.025
pseudouridine synthesis GO:0001522 13 0.024
ribonucleotide metabolic process GO:0009259 377 0.024
ribonucleoside metabolic process GO:0009119 389 0.024
single organism developmental process GO:0044767 258 0.024
dna templated transcription initiation GO:0006352 71 0.024
ribonucleoside monophosphate catabolic process GO:0009158 224 0.024
membrane docking GO:0022406 22 0.024
regulation of lipid metabolic process GO:0019216 45 0.024
positive regulation of cell cycle process GO:0090068 31 0.024
regulation of catabolic process GO:0009894 199 0.023
invasive growth in response to glucose limitation GO:0001403 61 0.023
modification dependent protein catabolic process GO:0019941 181 0.023
macromolecule methylation GO:0043414 85 0.023
nucleoside metabolic process GO:0009116 394 0.023
regulation of localization GO:0032879 127 0.022
localization within membrane GO:0051668 29 0.022
regulation of molecular function GO:0065009 320 0.022
nucleoside phosphate biosynthetic process GO:1901293 80 0.022
protein targeting to nucleus GO:0044744 57 0.022
regulation of protein kinase activity GO:0045859 67 0.022
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.022
vesicle organization GO:0016050 68 0.022
regulation of vesicle mediated transport GO:0060627 39 0.022
reproduction of a single celled organism GO:0032505 191 0.022
purine ribonucleotide metabolic process GO:0009150 372 0.022
ribonucleoside triphosphate metabolic process GO:0009199 356 0.022
organophosphate biosynthetic process GO:0090407 182 0.022
amine metabolic process GO:0009308 51 0.022
endomembrane system organization GO:0010256 74 0.022
negative regulation of catalytic activity GO:0043086 60 0.021
cellular response to starvation GO:0009267 90 0.021
sexual reproduction GO:0019953 216 0.021
regulation of cellular component organization GO:0051128 334 0.021
pyrimidine containing compound biosynthetic process GO:0072528 33 0.021
macromolecular complex disassembly GO:0032984 80 0.021
purine ribonucleoside metabolic process GO:0046128 380 0.021
protein processing GO:0016485 64 0.021
homeostatic process GO:0042592 227 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.021
regulation of cellular catabolic process GO:0031329 195 0.021
plasma membrane organization GO:0007009 21 0.020
positive regulation of secretion by cell GO:1903532 2 0.020
cellular amino acid metabolic process GO:0006520 225 0.020
rna splicing via transesterification reactions GO:0000375 118 0.020
phospholipid metabolic process GO:0006644 125 0.020
mitochondrial rna metabolic process GO:0000959 24 0.020
non recombinational repair GO:0000726 33 0.020
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.020
cellular component morphogenesis GO:0032989 97 0.019
negative regulation of protein processing GO:0010955 33 0.019
rna phosphodiester bond hydrolysis GO:0090501 112 0.019
cellular response to nutrient levels GO:0031669 144 0.019
coenzyme biosynthetic process GO:0009108 66 0.019
golgi to plasma membrane transport GO:0006893 33 0.019
recombinational repair GO:0000725 64 0.019
nucleotide catabolic process GO:0009166 330 0.019
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 79 0.019
exonucleolytic trimming involved in rrna processing GO:0000459 19 0.019
response to nutrient GO:0007584 52 0.018
protein complex disassembly GO:0043241 70 0.018
positive regulation of intracellular protein transport GO:0090316 3 0.018
macromolecule catabolic process GO:0009057 383 0.018
maintenance of location GO:0051235 66 0.018
regulation of protein modification process GO:0031399 110 0.018
regulation of mitotic cell cycle GO:0007346 107 0.018
response to uv GO:0009411 4 0.018
regulation of protein processing GO:0070613 34 0.018
establishment of mitotic spindle orientation GO:0000132 10 0.017
regulation of response to extracellular stimulus GO:0032104 20 0.017
protein acetylation GO:0006473 59 0.017
purine nucleoside triphosphate metabolic process GO:0009144 356 0.017
gtp catabolic process GO:0006184 107 0.017
regulation of mrna splicing via spliceosome GO:0048024 3 0.017
trna export from nucleus GO:0006409 16 0.017
nucleoside monophosphate catabolic process GO:0009125 224 0.017
positive regulation of cellular component biogenesis GO:0044089 45 0.017
organic cyclic compound catabolic process GO:1901361 499 0.017
establishment of cell polarity GO:0030010 64 0.017
regulation of translational elongation GO:0006448 25 0.016
cellular response to nitrogen compound GO:1901699 14 0.016
response to hypoxia GO:0001666 4 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.016
negative regulation of signaling GO:0023057 30 0.016
purine nucleoside catabolic process GO:0006152 330 0.016
translation GO:0006412 230 0.016
chromatin modification GO:0016568 200 0.016
rna polyadenylation GO:0043631 26 0.016
meiotic recombination checkpoint GO:0051598 9 0.016
histone methylation GO:0016571 28 0.016
cellular response to organic substance GO:0071310 159 0.016
response to external stimulus GO:0009605 158 0.016
negative regulation of proteolysis GO:0045861 33 0.016
cellular response to extracellular stimulus GO:0031668 150 0.016
nucleoside catabolic process GO:0009164 335 0.016
response to calcium ion GO:0051592 1 0.016
regulation of cellular component biogenesis GO:0044087 112 0.016
ribonucleoside triphosphate catabolic process GO:0009203 327 0.016
nucleobase containing compound catabolic process GO:0034655 479 0.016
ncrna 5 end processing GO:0034471 32 0.016
cell development GO:0048468 107 0.015
protein complex biogenesis GO:0070271 314 0.015
carbohydrate derivative catabolic process GO:1901136 339 0.015
positive regulation of ras protein signal transduction GO:0046579 3 0.015
establishment or maintenance of cell polarity GO:0007163 96 0.015
purine containing compound biosynthetic process GO:0072522 53 0.015
anatomical structure formation involved in morphogenesis GO:0048646 136 0.015
nucleoside triphosphate metabolic process GO:0009141 364 0.015
regulation of cellular amine metabolic process GO:0033238 21 0.015
nucleoside phosphate catabolic process GO:1901292 331 0.015
cellular nitrogen compound catabolic process GO:0044270 494 0.015
chromosome organization involved in meiosis GO:0070192 32 0.015
multi organism process GO:0051704 233 0.015
regulation of chromatin modification GO:1903308 23 0.015
regulation of filamentous growth GO:0010570 38 0.015
double strand break repair via nonhomologous end joining GO:0006303 27 0.015
cell morphogenesis GO:0000902 30 0.014
oxidation reduction process GO:0055114 353 0.014
positive regulation of cytoplasmic transport GO:1903651 4 0.014
regulation of transport GO:0051049 85 0.014
mitotic sister chromatid cohesion GO:0007064 38 0.014
regulation of protein phosphorylation GO:0001932 75 0.014
rna dependent dna replication GO:0006278 25 0.014
mating type switching GO:0007533 28 0.014
purine containing compound metabolic process GO:0072521 400 0.014
peptidyl lysine acetylation GO:0018394 52 0.014
protein complex localization GO:0031503 32 0.014
membrane invagination GO:0010324 43 0.014
positive regulation of intracellular transport GO:0032388 4 0.014
actin filament organization GO:0007015 56 0.014
cellular component disassembly GO:0022411 86 0.014
cellular response to oxygen containing compound GO:1901701 43 0.014
regulation of translation GO:0006417 89 0.014
reciprocal meiotic recombination GO:0007131 54 0.014
alcohol biosynthetic process GO:0046165 75 0.014
developmental process involved in reproduction GO:0003006 159 0.014
establishment of mitotic spindle localization GO:0040001 12 0.014
trna transport GO:0051031 19 0.014
intronic snorna processing GO:0031070 9 0.014
ribonucleoside biosynthetic process GO:0042455 37 0.013
translational elongation GO:0006414 32 0.013
positive regulation of mitotic cell cycle GO:0045931 16 0.013
nucleoside triphosphate catabolic process GO:0009143 329 0.013
glutamine family amino acid metabolic process GO:0009064 31 0.013
single organism reproductive process GO:0044702 159 0.013
rna splicing via transesterification reactions with guanosine as nucleophile GO:0000376 10 0.013
regulation of chromatin organization GO:1902275 23 0.013
carboxylic acid catabolic process GO:0046395 71 0.013
positive regulation of secretion GO:0051047 2 0.013
ribonucleoside catabolic process GO:0042454 332 0.013
multi organism cellular process GO:0044764 120 0.013
vacuolar transport GO:0007034 145 0.013
cellular amine metabolic process GO:0044106 51 0.013
positive regulation of nucleocytoplasmic transport GO:0046824 4 0.013
heterochromatin organization GO:0070828 11 0.013
purine nucleoside monophosphate catabolic process GO:0009128 224 0.013
response to starvation GO:0042594 96 0.013
negative regulation of response to stimulus GO:0048585 40 0.013
cell cycle phase transition GO:0044770 144 0.013
cellular response to hypoxia GO:0071456 4 0.012
response to osmotic stress GO:0006970 83 0.012
snrna pseudouridine synthesis GO:0031120 6 0.012
protein localization to chromosome GO:0034502 28 0.012
establishment of spindle orientation GO:0051294 10 0.012
trna transcription GO:0009304 19 0.012
multi organism reproductive process GO:0044703 216 0.012
negative regulation of mitotic cell cycle GO:0045930 63 0.012
regulation of chromosome organization GO:0033044 66 0.012
er to golgi vesicle mediated transport GO:0006888 86 0.012
positive regulation of cell cycle GO:0045787 32 0.012
regulation of phosphate metabolic process GO:0019220 230 0.012
positive regulation of apoptotic process GO:0043065 3 0.012
lipid biosynthetic process GO:0008610 170 0.012
posttranscriptional regulation of gene expression GO:0010608 115 0.012
mrna cleavage GO:0006379 26 0.012
protein modification by small protein removal GO:0070646 29 0.012
cytokinesis GO:0000910 92 0.012
oxidoreduction coenzyme metabolic process GO:0006733 58 0.012
regulation of response to stimulus GO:0048583 157 0.012
dicarboxylic acid metabolic process GO:0043648 20 0.012
regulation of hormone levels GO:0010817 1 0.012
ribonucleoside monophosphate metabolic process GO:0009161 265 0.012
trna methylation GO:0030488 21 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 13 0.011
positive regulation of rna metabolic process GO:0051254 294 0.011
aromatic compound catabolic process GO:0019439 491 0.011
dna integrity checkpoint GO:0031570 41 0.011
positive regulation of catabolic process GO:0009896 135 0.011
mitotic nuclear division GO:0007067 131 0.011
negative regulation of catabolic process GO:0009895 43 0.011
lysine biosynthetic process GO:0009085 7 0.011
peptidyl lysine modification GO:0018205 77 0.011
amine biosynthetic process GO:0009309 9 0.011
regulation of cellular amino acid metabolic process GO:0006521 16 0.011
atp catabolic process GO:0006200 224 0.011
pyrimidine nucleobase biosynthetic process GO:0019856 9 0.011
regulation of cellular localization GO:0060341 50 0.011
regulation of mitotic cell cycle phase transition GO:1901990 68 0.011
regulation of hydrolase activity GO:0051336 133 0.011
protein phosphorylation GO:0006468 197 0.011
negative regulation of chromatin modification GO:1903309 9 0.011
regulation of macroautophagy GO:0016241 15 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.011
nucleoside biosynthetic process GO:0009163 38 0.011
regulation of cellular ketone metabolic process GO:0010565 42 0.011
negative regulation of gene silencing GO:0060969 27 0.011
cellular response to heat GO:0034605 53 0.011
spindle pole body duplication GO:0030474 17 0.011
detection of chemical stimulus GO:0009593 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 73 0.011
sulfur compound biosynthetic process GO:0044272 53 0.011
phospholipid biosynthetic process GO:0008654 89 0.011
regulation of histone acetylation GO:0035065 7 0.010
response to metal ion GO:0010038 24 0.010
organic hydroxy compound biosynthetic process GO:1901617 81 0.010
sulfur amino acid metabolic process GO:0000096 34 0.010
negative regulation of protein maturation GO:1903318 33 0.010
atp metabolic process GO:0046034 251 0.010
regulation of rna splicing GO:0043484 3 0.010
translational initiation GO:0006413 56 0.010
mrna transport GO:0051028 60 0.010
pyridine nucleotide metabolic process GO:0019362 45 0.010
regulation of dna templated transcription elongation GO:0032784 44 0.010
protein folding GO:0006457 94 0.010
nucleobase biosynthetic process GO:0046112 17 0.010
response to temperature stimulus GO:0009266 74 0.010
reproductive process GO:0022414 248 0.010
cell surface receptor signaling pathway GO:0007166 38 0.010
alcohol metabolic process GO:0006066 112 0.010
response to oxidative stress GO:0006979 99 0.010
spindle organization GO:0007051 37 0.010

MDN1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019