Saccharomyces cerevisiae

105 known processes

HSP78 (YDR258C)

Hsp78p

HSP78 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of biosynthetic process GO:0009891 336 0.823
positive regulation of cellular biosynthetic process GO:0031328 336 0.811
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.729
positive regulation of gene expression GO:0010628 321 0.589
protein complex biogenesis GO:0070271 314 0.570
protein refolding GO:0042026 16 0.563
positive regulation of transcription dna templated GO:0045893 286 0.538
positive regulation of macromolecule metabolic process GO:0010604 394 0.474
positive regulation of rna metabolic process GO:0051254 294 0.408
protein folding GO:0006457 94 0.373
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.352
gene silencing GO:0016458 151 0.332
positive regulation of rna biosynthetic process GO:1902680 286 0.301
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.296
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.289
positive regulation of nucleic acid templated transcription GO:1903508 286 0.244
negative regulation of cellular metabolic process GO:0031324 407 0.243
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.219
cellular protein complex assembly GO:0043623 209 0.204
negative regulation of nucleic acid templated transcription GO:1903507 260 0.204
response to heat GO:0009408 69 0.203
negative regulation of gene expression GO:0010629 312 0.197
protein complex assembly GO:0006461 302 0.195
cellular response to chemical stimulus GO:0070887 315 0.186
regulation of gene expression epigenetic GO:0040029 147 0.179
negative regulation of transcription dna templated GO:0045892 258 0.179
response to chemical GO:0042221 390 0.176
mrna metabolic process GO:0016071 269 0.160
cellular nitrogen compound catabolic process GO:0044270 494 0.159
macromolecule catabolic process GO:0009057 383 0.158
proteolysis GO:0006508 268 0.155
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.153
negative regulation of macromolecule metabolic process GO:0010605 375 0.151
regulation of cellular component organization GO:0051128 334 0.148
negative regulation of rna metabolic process GO:0051253 262 0.139
negative regulation of biosynthetic process GO:0009890 312 0.134
response to abiotic stimulus GO:0009628 159 0.125
chromatin silencing GO:0006342 147 0.118
cell communication GO:0007154 345 0.110
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.106
signal transduction GO:0007165 208 0.106
nucleobase containing compound catabolic process GO:0034655 479 0.105
response to temperature stimulus GO:0009266 74 0.103
cellular response to dna damage stimulus GO:0006974 287 0.098
cellular lipid metabolic process GO:0044255 229 0.097
replicative cell aging GO:0001302 46 0.095
organic cyclic compound catabolic process GO:1901361 499 0.091
cellular response to external stimulus GO:0071496 150 0.090
single organism signaling GO:0044700 208 0.087
negative regulation of cellular component organization GO:0051129 109 0.085
signaling GO:0023052 208 0.080
purine ribonucleoside catabolic process GO:0046130 330 0.079
regulation of biological quality GO:0065008 391 0.077
regulation of growth GO:0040008 50 0.076
cellular macromolecule catabolic process GO:0044265 363 0.075
regulation of cellular catabolic process GO:0031329 195 0.072
glycerolipid metabolic process GO:0046486 108 0.069
dna repair GO:0006281 236 0.068
regulation of signaling GO:0023051 119 0.067
negative regulation of rna biosynthetic process GO:1902679 260 0.065
regulation of cellular ketone metabolic process GO:0010565 42 0.065
cellular response to starvation GO:0009267 90 0.061
purine nucleoside triphosphate metabolic process GO:0009144 356 0.061
heterocycle catabolic process GO:0046700 494 0.059
negative regulation of molecular function GO:0044092 68 0.059
ribonucleotide catabolic process GO:0009261 327 0.059
cellular response to extracellular stimulus GO:0031668 150 0.057
aromatic compound catabolic process GO:0019439 491 0.057
ribonucleoside catabolic process GO:0042454 332 0.056
nucleoside metabolic process GO:0009116 394 0.055
mrna processing GO:0006397 185 0.054
organophosphate catabolic process GO:0046434 338 0.054
protein targeting to mitochondrion GO:0006626 56 0.053
negative regulation of cellular biosynthetic process GO:0031327 312 0.053
regulation of catabolic process GO:0009894 199 0.053
sexual reproduction GO:0019953 216 0.052
purine nucleoside catabolic process GO:0006152 330 0.051
purine containing compound catabolic process GO:0072523 332 0.049
organophosphate metabolic process GO:0019637 597 0.049
ribonucleoside metabolic process GO:0009119 389 0.049
phosphorylation GO:0016310 291 0.049
disaccharide metabolic process GO:0005984 25 0.048
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.047
protein localization to organelle GO:0033365 337 0.047
reproductive process GO:0022414 248 0.046
regulation of protein metabolic process GO:0051246 237 0.046
purine ribonucleotide catabolic process GO:0009154 327 0.044
cellular response to nutrient levels GO:0031669 144 0.043
nucleoside phosphate catabolic process GO:1901292 331 0.043
carbohydrate biosynthetic process GO:0016051 82 0.043
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.041
positive regulation of cellular component organization GO:0051130 116 0.040
cellular ketone metabolic process GO:0042180 63 0.040
membrane organization GO:0061024 276 0.040
protein localization to mitochondrion GO:0070585 63 0.039
lipid biosynthetic process GO:0008610 170 0.039
negative regulation of cellular protein metabolic process GO:0032269 85 0.038
chromatin modification GO:0016568 200 0.038
single organism carbohydrate metabolic process GO:0044723 237 0.037
carbohydrate derivative metabolic process GO:1901135 549 0.037
ribonucleoside triphosphate catabolic process GO:0009203 327 0.037
positive regulation of nucleotide catabolic process GO:0030813 97 0.037
positive regulation of molecular function GO:0044093 185 0.036
nucleotide catabolic process GO:0009166 330 0.036
purine nucleotide catabolic process GO:0006195 328 0.035
regulation of cellular protein metabolic process GO:0032268 232 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.035
monosaccharide biosynthetic process GO:0046364 31 0.035
lipid metabolic process GO:0006629 269 0.035
ribonucleoprotein complex subunit organization GO:0071826 152 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.034
regulation of response to stimulus GO:0048583 157 0.034
positive regulation of apoptotic process GO:0043065 3 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.033
protein ubiquitination GO:0016567 118 0.033
multi organism reproductive process GO:0044703 216 0.032
protein maturation GO:0051604 76 0.032
peptidyl amino acid modification GO:0018193 116 0.032
regulation of hydrolase activity GO:0051336 133 0.032
trehalose metabolic process GO:0005991 11 0.032
protein modification by small protein conjugation or removal GO:0070647 172 0.031
cellular response to heat GO:0034605 53 0.030
nuclear transport GO:0051169 165 0.030
posttranscriptional regulation of gene expression GO:0010608 115 0.030
regulation of phosphorus metabolic process GO:0051174 230 0.030
negative regulation of protein modification process GO:0031400 37 0.030
cellular amine metabolic process GO:0044106 51 0.030
protein catabolic process GO:0030163 221 0.030
mrna splicing via spliceosome GO:0000398 108 0.029
cellular carbohydrate metabolic process GO:0044262 135 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.029
purine nucleoside monophosphate catabolic process GO:0009128 224 0.028
oxidation reduction process GO:0055114 353 0.028
negative regulation of response to stimulus GO:0048585 40 0.028
vesicle mediated transport GO:0016192 335 0.028
regulation of cell communication GO:0010646 124 0.027
purine containing compound metabolic process GO:0072521 400 0.027
regulation of cellular component biogenesis GO:0044087 112 0.027
cell growth GO:0016049 89 0.027
chromatin organization GO:0006325 242 0.026
oxoacid metabolic process GO:0043436 351 0.026
regulation of organelle organization GO:0033043 243 0.026
ion homeostasis GO:0050801 118 0.026
negative regulation of protein metabolic process GO:0051248 85 0.026
ribonucleoprotein complex disassembly GO:0032988 11 0.025
chaperone mediated protein folding GO:0061077 3 0.025
single organism catabolic process GO:0044712 619 0.025
positive regulation of programmed cell death GO:0043068 3 0.025
nucleoside triphosphate catabolic process GO:0009143 329 0.025
ribonucleotide metabolic process GO:0009259 377 0.025
carbohydrate derivative catabolic process GO:1901136 339 0.024
purine nucleoside monophosphate metabolic process GO:0009126 262 0.024
ribonucleoside triphosphate metabolic process GO:0009199 356 0.023
intracellular protein transmembrane transport GO:0065002 80 0.023
purine nucleoside triphosphate catabolic process GO:0009146 329 0.023
organic hydroxy compound metabolic process GO:1901615 125 0.023
purine ribonucleoside metabolic process GO:0046128 380 0.023
macromolecular complex disassembly GO:0032984 80 0.022
positive regulation of cell death GO:0010942 3 0.022
regulation of cell growth GO:0001558 29 0.022
nucleoside catabolic process GO:0009164 335 0.022
cation homeostasis GO:0055080 105 0.022
cellular component disassembly GO:0022411 86 0.022
regulation of protein complex assembly GO:0043254 77 0.022
organonitrogen compound catabolic process GO:1901565 404 0.022
translation GO:0006412 230 0.021
nucleoside monophosphate catabolic process GO:0009125 224 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.021
protein processing GO:0016485 64 0.021
nucleotide metabolic process GO:0009117 453 0.021
regulation of transport GO:0051049 85 0.020
regulation of dna metabolic process GO:0051052 100 0.020
glycosyl compound metabolic process GO:1901657 398 0.020
positive regulation of catabolic process GO:0009896 135 0.020
single organism membrane organization GO:0044802 275 0.020
purine nucleotide metabolic process GO:0006163 376 0.020
ribose phosphate metabolic process GO:0019693 384 0.020
nucleocytoplasmic transport GO:0006913 163 0.020
protein phosphorylation GO:0006468 197 0.019
cellular metal ion homeostasis GO:0006875 78 0.019
positive regulation of secretion GO:0051047 2 0.019
monovalent inorganic cation homeostasis GO:0055067 32 0.019
single organism developmental process GO:0044767 258 0.019
regulation of protein processing GO:0070613 34 0.019
regulation of signal transduction GO:0009966 114 0.018
atp catabolic process GO:0006200 224 0.018
apoptotic process GO:0006915 30 0.017
response to unfolded protein GO:0006986 29 0.017
ethanol catabolic process GO:0006068 1 0.017
ribonucleoprotein complex assembly GO:0022618 143 0.017
regulation of intracellular signal transduction GO:1902531 78 0.017
cellular cation homeostasis GO:0030003 100 0.017
regulation of protein modification process GO:0031399 110 0.017
nucleic acid phosphodiester bond hydrolysis GO:0090305 194 0.017
nuclear export GO:0051168 124 0.016
regulation of cellular amine metabolic process GO:0033238 21 0.016
negative regulation of mrna processing GO:0050686 2 0.016
g1 s transition of mitotic cell cycle GO:0000082 64 0.016
nucleoside monophosphate metabolic process GO:0009123 267 0.016
negative regulation of organelle organization GO:0010639 103 0.016
dna recombination GO:0006310 172 0.016
positive regulation of cellular protein metabolic process GO:0032270 89 0.016
positive regulation of transcription from rna polymerase ii promoter in response to increased salt GO:0061404 4 0.016
single organism reproductive process GO:0044702 159 0.016
phosphatidylinositol metabolic process GO:0046488 62 0.015
ribonucleoside monophosphate catabolic process GO:0009158 224 0.015
nucleobase containing small molecule metabolic process GO:0055086 491 0.015
aging GO:0007568 71 0.015
cellular homeostasis GO:0019725 138 0.015
protein transport GO:0015031 345 0.015
regulation of molecular function GO:0065009 320 0.015
regulation of translation GO:0006417 89 0.015
programmed cell death GO:0012501 30 0.015
cell surface receptor signaling pathway GO:0007166 38 0.015
positive regulation of cellular catabolic process GO:0031331 128 0.015
developmental process GO:0032502 261 0.015
response to topologically incorrect protein GO:0035966 38 0.014
carboxylic acid metabolic process GO:0019752 338 0.014
positive regulation of secretion by cell GO:1903532 2 0.014
response to oxidative stress GO:0006979 99 0.014
regulation of ethanol catabolic process GO:1900065 1 0.014
energy derivation by oxidation of organic compounds GO:0015980 125 0.014
purine ribonucleotide metabolic process GO:0009150 372 0.014
intracellular protein transport GO:0006886 319 0.014
protein modification by small protein conjugation GO:0032446 144 0.014
positive regulation of hydrolase activity GO:0051345 112 0.014
intracellular signal transduction GO:0035556 112 0.014
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter GO:1900464 2 0.014
negative regulation of gene expression epigenetic GO:0045814 147 0.014
response to uv GO:0009411 4 0.014
regulation of catalytic activity GO:0050790 307 0.013
regulation of nucleotide metabolic process GO:0006140 110 0.013
phospholipid biosynthetic process GO:0008654 89 0.013
regulation of purine nucleotide metabolic process GO:1900542 109 0.013
glycosyl compound catabolic process GO:1901658 335 0.013
nuclear transcribed mrna catabolic process GO:0000956 89 0.013
atp metabolic process GO:0046034 251 0.013
positive regulation of organelle organization GO:0010638 85 0.013
negative regulation of signal transduction GO:0009968 30 0.013
nucleoside triphosphate metabolic process GO:0009141 364 0.013
carbohydrate derivative biosynthetic process GO:1901137 181 0.013
protein transmembrane transport GO:0071806 82 0.013
regulation of chromatin silencing GO:0031935 39 0.013
cellular response to endogenous stimulus GO:0071495 22 0.013
alcohol metabolic process GO:0006066 112 0.012
regulation of sodium ion transport GO:0002028 1 0.012
carbohydrate metabolic process GO:0005975 252 0.012
cellular ion homeostasis GO:0006873 112 0.012
homeostatic process GO:0042592 227 0.012
response to inorganic substance GO:0010035 47 0.012
positive regulation of protein metabolic process GO:0051247 93 0.012
cellular response to oxidative stress GO:0034599 94 0.012
death GO:0016265 30 0.012
protein import GO:0017038 122 0.012
mitochondrion organization GO:0007005 261 0.012
cell aging GO:0007569 70 0.012
regulation of phosphate metabolic process GO:0019220 230 0.012
regulation of purine nucleotide catabolic process GO:0033121 106 0.012
mrna catabolic process GO:0006402 93 0.012
response to extracellular stimulus GO:0009991 156 0.012
nucleoside phosphate metabolic process GO:0006753 458 0.012
regulation of proteolysis GO:0030162 44 0.011
cellular response to oxygen containing compound GO:1901701 43 0.011
primary alcohol catabolic process GO:0034310 1 0.011
cellular response to anoxia GO:0071454 3 0.011
negative regulation of catalytic activity GO:0043086 60 0.011
ubiquitin dependent protein catabolic process GO:0006511 181 0.011
ribonucleoside monophosphate metabolic process GO:0009161 265 0.011
protein localization to nucleus GO:0034504 74 0.011
positive regulation of transcription from rna polymerase ii promoter in response to ethanol GO:0061410 3 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.011
positive regulation of peroxisome organization GO:1900064 1 0.011
steroid metabolic process GO:0008202 47 0.011
response to external stimulus GO:0009605 158 0.011
double strand break repair GO:0006302 105 0.011
positive regulation of fatty acid beta oxidation GO:0032000 3 0.011
negative regulation of protein processing GO:0010955 33 0.010
cellular response to nutrient GO:0031670 50 0.010
multi organism process GO:0051704 233 0.010
monocarboxylic acid metabolic process GO:0032787 122 0.010
amine metabolic process GO:0009308 51 0.010
regulation of lipid metabolic process GO:0019216 45 0.010
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.010

HSP78 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org