Saccharomyces cerevisiae

239 known processes

PAF1 (YBR279W)

Paf1p

PAF1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription elongation from rna polymerase ii promoter GO:0006368 81 0.974
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.918
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.903
chromatin organization GO:0006325 242 0.894
positive regulation of rna biosynthetic process GO:1902680 286 0.861
transcription from rna polymerase i promoter GO:0006360 63 0.814
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 38 0.809
positive regulation of transcription from rna polymerase i promoter GO:0045943 19 0.701
regulation of transcription from rna polymerase i promoter GO:0006356 36 0.671
negative regulation of macromolecule metabolic process GO:0010605 375 0.630
regulation of response to stress GO:0080134 57 0.614
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 40 0.601
histone h2b conserved c terminal lysine ubiquitination GO:0071894 6 0.598
positive regulation of macromolecule metabolic process GO:0010604 394 0.596
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.563
positive regulation of dna templated transcription elongation GO:0032786 42 0.548
positive regulation of gene expression GO:0010628 321 0.543
protein modification by small protein conjugation GO:0032446 144 0.520
regulation of cellular protein metabolic process GO:0032268 232 0.506
methylation GO:0032259 101 0.490
protein alkylation GO:0008213 48 0.487
dna templated transcription initiation GO:0006352 71 0.485
single organism cellular localization GO:1902580 375 0.483
regulation of dna templated transcription elongation GO:0032784 44 0.447
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.447
regulation of chromatin modification GO:1903308 23 0.444
macromolecule methylation GO:0043414 85 0.430
regulation of response to dna damage stimulus GO:2001020 17 0.429
phosphorylation of rna polymerase ii c terminal domain GO:0070816 20 0.412
protein ubiquitination GO:0016567 118 0.410
dna templated transcription elongation GO:0006354 91 0.359
regulation of organelle organization GO:0033043 243 0.355
signal transduction GO:0007165 208 0.345
regulation of cellular component biogenesis GO:0044087 112 0.338
histone h3 k4 methylation GO:0051568 18 0.321
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.309
positive regulation of transcription dna templated GO:0045893 286 0.305
regulation of histone ubiquitination GO:0033182 7 0.301
regulation of cellular response to stress GO:0080135 50 0.288
negative regulation of cellular metabolic process GO:0031324 407 0.279
negative regulation of gene expression GO:0010629 312 0.272
protein modification by small protein conjugation or removal GO:0070647 172 0.268
single organism membrane organization GO:0044802 275 0.265
regulation of protein phosphorylation GO:0001932 75 0.262
ncrna processing GO:0034470 330 0.257
regulation of protein metabolic process GO:0051246 237 0.255
cellular amino acid metabolic process GO:0006520 225 0.248
response to organic substance GO:0010033 182 0.238
intracellular signal transduction GO:0035556 112 0.232
histone ubiquitination GO:0016574 17 0.226
protein complex biogenesis GO:0070271 314 0.226
regulation of protein complex assembly GO:0043254 77 0.221
regulation of cellular component organization GO:0051128 334 0.216
negative regulation of biosynthetic process GO:0009890 312 0.212
regulation of chromatin organization GO:1902275 23 0.209
positive regulation of protein metabolic process GO:0051247 93 0.208
negative regulation of nucleic acid templated transcription GO:1903507 260 0.206
mitotic cell cycle GO:0000278 306 0.198
protein phosphorylation GO:0006468 197 0.197
transcription elongation from rna polymerase i promoter GO:0006362 10 0.197
regulation of response to stimulus GO:0048583 157 0.195
transcription coupled nucleotide excision repair GO:0006283 16 0.194
nucleotide excision repair GO:0006289 50 0.194
negative regulation of cellular biosynthetic process GO:0031327 312 0.192
single organism signaling GO:0044700 208 0.188
positive regulation of rna metabolic process GO:0051254 294 0.183
positive regulation of nucleic acid templated transcription GO:1903508 286 0.174
regulation of protein ubiquitination GO:0031396 20 0.172
protein complex assembly GO:0006461 302 0.171
regulation of histone modification GO:0031056 18 0.171
regulation of phosphorylation GO:0042325 86 0.170
protein methylation GO:0006479 48 0.165
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.162
regulation of phosphorus metabolic process GO:0051174 230 0.160
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.160
vacuole organization GO:0007033 75 0.158
regulation of histone h2b ubiquitination GO:2001166 6 0.156
dna templated transcription termination GO:0006353 42 0.154
multi organism process GO:0051704 233 0.149
negative regulation of transcription dna templated GO:0045892 258 0.148
mrna processing GO:0006397 185 0.147
vesicle mediated transport GO:0016192 335 0.142
regulation of gene expression epigenetic GO:0040029 147 0.137
positive regulation of cellular protein metabolic process GO:0032270 89 0.134
cellular component disassembly GO:0022411 86 0.124
histone lysine methylation GO:0034968 26 0.120
histone modification GO:0016570 119 0.120
membrane organization GO:0061024 276 0.118
single organism catabolic process GO:0044712 619 0.117
positive regulation of protein modification process GO:0031401 49 0.109
positive regulation of transcription elongation from rna polymerase i promoter GO:2001209 7 0.105
cell surface receptor signaling pathway GO:0007166 38 0.104
regulation of dna repair GO:0006282 14 0.097
regulation of chromosome organization GO:0033044 66 0.094
organic acid metabolic process GO:0006082 352 0.093
peptidyl lysine methylation GO:0018022 24 0.091
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 40 0.088
positive regulation of cellular biosynthetic process GO:0031328 336 0.086
oxoacid metabolic process GO:0043436 351 0.085
negative regulation of rna biosynthetic process GO:1902679 260 0.084
positive regulation of biosynthetic process GO:0009891 336 0.082
protein dna complex subunit organization GO:0071824 153 0.081
regulation of transcription coupled nucleotide excision repair GO:0090262 7 0.078
signaling GO:0023052 208 0.078
cell communication GO:0007154 345 0.077
regulation of transcription elongation from rna polymerase i promoter GO:2001207 7 0.075
cellular response to dna damage stimulus GO:0006974 287 0.072
peptidyl amino acid modification GO:0018193 116 0.068
ribonucleoprotein complex subunit organization GO:0071826 152 0.068
phosphorylation GO:0016310 291 0.067
anatomical structure formation involved in morphogenesis GO:0048646 136 0.065
regulation of phosphate metabolic process GO:0019220 230 0.064
mitotic cell cycle process GO:1903047 294 0.064
aromatic compound catabolic process GO:0019439 491 0.063
regulation of cell communication GO:0010646 124 0.063
single organism developmental process GO:0044767 258 0.062
dna replication GO:0006260 147 0.062
dna repair GO:0006281 236 0.061
transcription initiation from rna polymerase ii promoter GO:0006367 55 0.061
regulation of histone methylation GO:0031060 8 0.059
phosphorylation of rna polymerase ii c terminal domain serine 2 residues GO:0071619 4 0.059
positive regulation of phosphorus metabolic process GO:0010562 147 0.059
protein monoubiquitination GO:0006513 13 0.058
ncrna 3 end processing GO:0043628 44 0.057
regulation of protein modification process GO:0031399 110 0.057
positive regulation of phosphate metabolic process GO:0045937 147 0.055
macromolecule catabolic process GO:0009057 383 0.054
posttranscriptional regulation of gene expression GO:0010608 115 0.051
regulation of mitotic cell cycle GO:0007346 107 0.051
regulation of cell cycle GO:0051726 195 0.050
regulation of histone h3 k4 methylation GO:0051569 5 0.050
regulation of cellular ketone metabolic process GO:0010565 42 0.049
regulation of histone h2b conserved c terminal lysine ubiquitination GO:2001173 5 0.048
peptidyl lysine modification GO:0018205 77 0.048
ribonucleoprotein complex assembly GO:0022618 143 0.047
cellular ketone metabolic process GO:0042180 63 0.047
regulation of nucleotide excision repair GO:2000819 7 0.046
regulation of biological quality GO:0065008 391 0.046
response to external stimulus GO:0009605 158 0.046
carboxylic acid metabolic process GO:0019752 338 0.045
histone methylation GO:0016571 28 0.045
response to chemical GO:0042221 390 0.045
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.045
macromolecular complex disassembly GO:0032984 80 0.044
organelle localization GO:0051640 128 0.043
cellular response to chemical stimulus GO:0070887 315 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.041
negative regulation of rna metabolic process GO:0051253 262 0.041
regulation of protein modification by small protein conjugation or removal GO:1903320 29 0.040
regulation of catalytic activity GO:0050790 307 0.039
regulation of dna metabolic process GO:0051052 100 0.038
establishment of protein localization GO:0045184 367 0.037
positive regulation of organelle organization GO:0010638 85 0.037
regulation of signal transduction GO:0009966 114 0.037
chromatin modification GO:0016568 200 0.036
positive regulation of cellular component organization GO:0051130 116 0.033
localization within membrane GO:0051668 29 0.033
g1 s transition of mitotic cell cycle GO:0000082 64 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.031
autophagy GO:0006914 106 0.030
response to osmotic stress GO:0006970 83 0.030
regulation of localization GO:0032879 127 0.029
positive regulation of protein phosphorylation GO:0001934 28 0.028
dna templated transcriptional preinitiation complex assembly GO:0070897 51 0.028
gene silencing GO:0016458 151 0.028
protein localization to organelle GO:0033365 337 0.026
protein targeting GO:0006605 272 0.026
regulation of cellular amino acid metabolic process GO:0006521 16 0.026
positive regulation of cell communication GO:0010647 28 0.025
protein transport GO:0015031 345 0.025
cellular nitrogen compound catabolic process GO:0044270 494 0.024
regulation of signaling GO:0023051 119 0.023
positive regulation of phosphorylation GO:0042327 33 0.021
cell cycle phase transition GO:0044770 144 0.020
homeostatic process GO:0042592 227 0.020
response to organic cyclic compound GO:0014070 1 0.020
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 51 0.019
conjugation with cellular fusion GO:0000747 106 0.019
response to extracellular stimulus GO:0009991 156 0.018
cellular modified amino acid metabolic process GO:0006575 51 0.018
mrna metabolic process GO:0016071 269 0.018
heterocycle catabolic process GO:0046700 494 0.018
ion transport GO:0006811 274 0.018
reproductive process GO:0022414 248 0.018
endomembrane system organization GO:0010256 74 0.017
amine metabolic process GO:0009308 51 0.017
cellular response to oxygen containing compound GO:1901701 43 0.017
positive regulation of phosphorylation of rna polymerase ii c terminal domain GO:1901409 4 0.017
ribonucleotide catabolic process GO:0009261 327 0.017
protein targeting to vacuole GO:0006623 91 0.017
developmental process GO:0032502 261 0.017
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 19 0.016
single organism membrane budding GO:1902591 21 0.015
regulation of dna templated transcription in response to stress GO:0043620 51 0.015
lipid metabolic process GO:0006629 269 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 7 0.015
single organism membrane fusion GO:0044801 71 0.015
regulation of cellular catabolic process GO:0031329 195 0.014
gene silencing by rna GO:0031047 3 0.014
histone h3 k4 trimethylation GO:0080182 3 0.014
organic cyclic compound catabolic process GO:1901361 499 0.014
cellular response to organic substance GO:0071310 159 0.014
establishment of organelle localization GO:0051656 96 0.014
positive regulation of secretion by cell GO:1903532 2 0.014
regulation of cellular amine metabolic process GO:0033238 21 0.013
cell cycle g1 s phase transition GO:0044843 64 0.013
chromatin silencing GO:0006342 147 0.013
regulation of vesicle mediated transport GO:0060627 39 0.013
purine nucleoside triphosphate catabolic process GO:0009146 329 0.013
double strand break repair via nonhomologous end joining GO:0006303 27 0.013
ribonucleoside triphosphate metabolic process GO:0009199 356 0.013
response to abiotic stimulus GO:0009628 159 0.013
late endosome to vacuole transport GO:0045324 42 0.013
response to topologically incorrect protein GO:0035966 38 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
cellular developmental process GO:0048869 191 0.012
positive regulation of chromatin modification GO:1903310 13 0.012
purine containing compound metabolic process GO:0072521 400 0.012
regulation of catabolic process GO:0009894 199 0.012
nucleoside triphosphate catabolic process GO:0009143 329 0.012
cellular response to heat GO:0034605 53 0.012
modification dependent macromolecule catabolic process GO:0043632 203 0.012
purine nucleoside catabolic process GO:0006152 330 0.011
purine ribonucleotide catabolic process GO:0009154 327 0.011
ribonucleoside metabolic process GO:0009119 389 0.011
positive regulation of histone modification GO:0031058 12 0.011
regulation of translation GO:0006417 89 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
mitotic cell cycle phase transition GO:0044772 141 0.011
regulation of multi organism process GO:0043900 20 0.011
purine nucleotide catabolic process GO:0006195 328 0.011
sporulation GO:0043934 132 0.011
protein complex disassembly GO:0043241 70 0.010
sexual sporulation GO:0034293 113 0.010
regulation of molecular function GO:0065009 320 0.010
covalent chromatin modification GO:0016569 119 0.010

PAF1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org