Saccharomyces cerevisiae

51 known processes

APA1 (YCL050C)

Apa1p

(Aliases: DTP1)

APA1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 352 0.446
monocarboxylic acid metabolic process GO:0032787 122 0.272
generation of precursor metabolites and energy GO:0006091 147 0.151
translation GO:0006412 230 0.144
oxoacid metabolic process GO:0043436 351 0.138
negative regulation of cellular biosynthetic process GO:0031327 312 0.136
negative regulation of transcription dna templated GO:0045892 258 0.134
anatomical structure formation involved in morphogenesis GO:0048646 136 0.130
response to chemical GO:0042221 390 0.125
carboxylic acid metabolic process GO:0019752 338 0.120
cellular developmental process GO:0048869 191 0.118
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.110
regulation of carbohydrate metabolic process GO:0006109 43 0.102
glycolytic process GO:0006096 21 0.098
negative regulation of nucleic acid templated transcription GO:1903507 260 0.093
ribosome biogenesis GO:0042254 335 0.091
single organism catabolic process GO:0044712 619 0.087
developmental process involved in reproduction GO:0003006 159 0.086
cell differentiation GO:0030154 161 0.086
positive regulation of cellular biosynthetic process GO:0031328 336 0.085
cellular carbohydrate metabolic process GO:0044262 135 0.082
anatomical structure morphogenesis GO:0009653 160 0.079
single organism carbohydrate catabolic process GO:0044724 73 0.078
membrane organization GO:0061024 276 0.073
negative regulation of rna metabolic process GO:0051253 262 0.073
anatomical structure development GO:0048856 160 0.073
meiotic cell cycle process GO:1903046 229 0.072
negative regulation of biosynthetic process GO:0009890 312 0.069
oxidoreduction coenzyme metabolic process GO:0006733 58 0.066
negative regulation of macromolecule metabolic process GO:0010605 375 0.064
positive regulation of macromolecule metabolic process GO:0010604 394 0.064
protein transport GO:0015031 345 0.063
reproductive process GO:0022414 248 0.063
developmental process GO:0032502 261 0.062
purine nucleoside metabolic process GO:0042278 380 0.059
monosaccharide biosynthetic process GO:0046364 31 0.059
regulation of generation of precursor metabolites and energy GO:0043467 23 0.058
regulation of phosphorus metabolic process GO:0051174 230 0.058
sexual sporulation GO:0034293 113 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.057
establishment of protein localization GO:0045184 367 0.057
single organism reproductive process GO:0044702 159 0.057
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.054
alcohol biosynthetic process GO:0046165 75 0.054
carboxylic acid biosynthetic process GO:0046394 152 0.052
single organism developmental process GO:0044767 258 0.052
negative regulation of rna biosynthetic process GO:1902679 260 0.051
intracellular protein transport GO:0006886 319 0.050
protein targeting to membrane GO:0006612 52 0.050
cellular amino acid metabolic process GO:0006520 225 0.050
lipid transport GO:0006869 58 0.050
ribonucleotide metabolic process GO:0009259 377 0.050
establishment of protein localization to membrane GO:0090150 99 0.049
cellular response to nutrient levels GO:0031669 144 0.048
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.048
ubiquitin dependent protein catabolic process GO:0006511 181 0.047
multi organism process GO:0051704 233 0.046
single organism membrane organization GO:0044802 275 0.046
regulation of catabolic process GO:0009894 199 0.046
chromatin silencing GO:0006342 147 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.045
dephosphorylation GO:0016311 127 0.044
negative regulation of gene expression epigenetic GO:0045814 147 0.043
regulation of cellular catabolic process GO:0031329 195 0.042
response to nutrient levels GO:0031667 150 0.042
regulation of gene expression epigenetic GO:0040029 147 0.042
negative regulation of gene expression GO:0010629 312 0.042
multi organism reproductive process GO:0044703 216 0.041
protein targeting GO:0006605 272 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.041
energy reserve metabolic process GO:0006112 32 0.040
pyridine containing compound metabolic process GO:0072524 53 0.040
organophosphate catabolic process GO:0046434 338 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.039
purine ribonucleotide catabolic process GO:0009154 327 0.039
lipid biosynthetic process GO:0008610 170 0.039
pyruvate metabolic process GO:0006090 37 0.039
carbohydrate biosynthetic process GO:0016051 82 0.038
cellular modified amino acid metabolic process GO:0006575 51 0.038
organophosphate metabolic process GO:0019637 597 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.038
nucleoside phosphate metabolic process GO:0006753 458 0.038
regulation of phosphate metabolic process GO:0019220 230 0.037
cytoplasmic translation GO:0002181 65 0.037
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 137 0.037
pyridine nucleotide metabolic process GO:0019362 45 0.037
protein localization to organelle GO:0033365 337 0.037
single organism cellular localization GO:1902580 375 0.037
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 109 0.036
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.036
nucleotide metabolic process GO:0009117 453 0.036
nucleotide catabolic process GO:0009166 330 0.036
purine nucleotide metabolic process GO:0006163 376 0.036
protein targeting to er GO:0045047 39 0.036
organic hydroxy compound metabolic process GO:1901615 125 0.036
nucleoside triphosphate catabolic process GO:0009143 329 0.035
gene silencing GO:0016458 151 0.035
cell communication GO:0007154 345 0.035
rrna processing GO:0006364 227 0.034
cellular response to chemical stimulus GO:0070887 315 0.033
purine nucleoside triphosphate metabolic process GO:0009144 356 0.033
nucleoside phosphate catabolic process GO:1901292 331 0.033
regulation of cellular protein metabolic process GO:0032268 232 0.032
sporulation resulting in formation of a cellular spore GO:0030435 129 0.032
cellular response to external stimulus GO:0071496 150 0.032
ribonucleotide catabolic process GO:0009261 327 0.031
monosaccharide metabolic process GO:0005996 83 0.031
ribonucleoprotein complex export from nucleus GO:0071426 46 0.031
golgi vesicle transport GO:0048193 188 0.031
nucleobase containing small molecule metabolic process GO:0055086 491 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.031
protein folding GO:0006457 94 0.031
regulation of localization GO:0032879 127 0.030
cellular polysaccharide metabolic process GO:0044264 55 0.030
modification dependent macromolecule catabolic process GO:0043632 203 0.030
ribonucleoside metabolic process GO:0009119 389 0.030
alcohol metabolic process GO:0006066 112 0.030
vesicle mediated transport GO:0016192 335 0.029
reproductive process in single celled organism GO:0022413 145 0.029
phospholipid transport GO:0015914 23 0.029
coenzyme metabolic process GO:0006732 104 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.029
negative regulation of cellular metabolic process GO:0031324 407 0.029
rrna metabolic process GO:0016072 244 0.029
single organism carbohydrate metabolic process GO:0044723 237 0.029
hexose biosynthetic process GO:0019319 30 0.028
posttranscriptional regulation of gene expression GO:0010608 115 0.028
organic hydroxy compound biosynthetic process GO:1901617 81 0.028
multi organism cellular process GO:0044764 120 0.027
purine containing compound metabolic process GO:0072521 400 0.027
positive regulation of phosphorus metabolic process GO:0010562 147 0.027
carbohydrate derivative catabolic process GO:1901136 339 0.027
regulation of cellular component organization GO:0051128 334 0.027
regulation of organelle organization GO:0033043 243 0.027
glucan metabolic process GO:0044042 44 0.026
cellular homeostasis GO:0019725 138 0.026
cellular macromolecule catabolic process GO:0044265 363 0.026
mitotic nuclear division GO:0007067 131 0.026
purine ribonucleotide metabolic process GO:0009150 372 0.026
nucleoside metabolic process GO:0009116 394 0.025
macromolecule catabolic process GO:0009057 383 0.025
regulation of molecular function GO:0065009 320 0.025
cellular glucan metabolic process GO:0006073 44 0.025
positive regulation of biosynthetic process GO:0009891 336 0.024
ribonucleoside triphosphate catabolic process GO:0009203 327 0.024
response to organic substance GO:0010033 182 0.024
glycosyl compound metabolic process GO:1901657 398 0.024
mitotic cell cycle GO:0000278 306 0.024
positive regulation of cellular catabolic process GO:0031331 128 0.023
nucleobase containing compound catabolic process GO:0034655 479 0.023
protein localization to nucleus GO:0034504 74 0.023
positive regulation of catabolic process GO:0009896 135 0.023
response to temperature stimulus GO:0009266 74 0.023
organic acid biosynthetic process GO:0016053 152 0.023
organelle fission GO:0048285 272 0.023
response to abiotic stimulus GO:0009628 159 0.023
ion transport GO:0006811 274 0.022
positive regulation of phosphate metabolic process GO:0045937 147 0.022
response to heat GO:0009408 69 0.022
retrograde vesicle mediated transport golgi to er GO:0006890 28 0.022
mrna processing GO:0006397 185 0.022
ribonucleoside catabolic process GO:0042454 332 0.022
glycerophospholipid metabolic process GO:0006650 98 0.022
cellular metal ion homeostasis GO:0006875 78 0.022
establishment of ribosome localization GO:0033753 46 0.021
cellular response to nutrient GO:0031670 50 0.021
glycosyl compound catabolic process GO:1901658 335 0.021
purine nucleoside monophosphate metabolic process GO:0009126 262 0.021
ribonucleoside triphosphate metabolic process GO:0009199 356 0.021
purine ribonucleoside catabolic process GO:0046130 330 0.021
purine nucleoside catabolic process GO:0006152 330 0.020
ribose phosphate metabolic process GO:0019693 384 0.020
cellular amide metabolic process GO:0043603 59 0.020
protein modification by small protein conjugation or removal GO:0070647 172 0.020
hexose catabolic process GO:0019320 24 0.020
purine ribonucleoside metabolic process GO:0046128 380 0.020
trna metabolic process GO:0006399 151 0.020
glycogen metabolic process GO:0005977 30 0.020
establishment of protein localization to organelle GO:0072594 278 0.020
atp metabolic process GO:0046034 251 0.020
organonitrogen compound catabolic process GO:1901565 404 0.019
cellular response to extracellular stimulus GO:0031668 150 0.019
regulation of lipid metabolic process GO:0019216 45 0.019
regulation of nucleotide metabolic process GO:0006140 110 0.019
ribonucleoside monophosphate metabolic process GO:0009161 265 0.019
sexual reproduction GO:0019953 216 0.019
phospholipid biosynthetic process GO:0008654 89 0.019
mrna metabolic process GO:0016071 269 0.019
cellular carbohydrate biosynthetic process GO:0034637 49 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 394 0.019
purine containing compound catabolic process GO:0072523 332 0.018
carbohydrate derivative metabolic process GO:1901135 549 0.018
lipid metabolic process GO:0006629 269 0.018
homeostatic process GO:0042592 227 0.018
filamentous growth GO:0030447 124 0.018
reproduction of a single celled organism GO:0032505 191 0.018
protein localization to membrane GO:0072657 102 0.018
positive regulation of catalytic activity GO:0043085 178 0.018
vitamin metabolic process GO:0006766 41 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.018
cation homeostasis GO:0055080 105 0.017
nucleoside catabolic process GO:0009164 335 0.017
regulation of mitotic cell cycle GO:0007346 107 0.017
purine nucleoside triphosphate catabolic process GO:0009146 329 0.017
protein catabolic process GO:0030163 221 0.017
negative regulation of organelle organization GO:0010639 103 0.017
organonitrogen compound biosynthetic process GO:1901566 314 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.017
vacuolar transport GO:0007034 145 0.017
sporulation GO:0043934 132 0.017
nucleoside monophosphate metabolic process GO:0009123 267 0.017
proteasomal protein catabolic process GO:0010498 141 0.017
cellular lipid metabolic process GO:0044255 229 0.017
positive regulation of transcription dna templated GO:0045893 286 0.017
cellular amine metabolic process GO:0044106 51 0.017
regulation of cellular ketone metabolic process GO:0010565 42 0.017
response to nutrient GO:0007584 52 0.016
phosphorylation GO:0016310 291 0.016
signaling GO:0023052 208 0.016
positive regulation of nucleotide metabolic process GO:0045981 101 0.016
mitochondrion organization GO:0007005 261 0.016
phospholipid metabolic process GO:0006644 125 0.016
regulation of protein localization GO:0032880 62 0.016
regulation of transport GO:0051049 85 0.016
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.016
regulation of nucleotide catabolic process GO:0030811 106 0.016
cellular ketone metabolic process GO:0042180 63 0.016
small molecule biosynthetic process GO:0044283 258 0.016
cellular component disassembly GO:0022411 86 0.016
nucleocytoplasmic transport GO:0006913 163 0.015
transmembrane transport GO:0055085 349 0.015
purine nucleotide catabolic process GO:0006195 328 0.015
glycerolipid biosynthetic process GO:0045017 71 0.015
positive regulation of molecular function GO:0044093 185 0.015
regulation of transcription by glucose GO:0046015 13 0.015
organic cyclic compound catabolic process GO:1901361 499 0.015
positive regulation of gene expression GO:0010628 321 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.015
carbohydrate metabolic process GO:0005975 252 0.015
regulation of catalytic activity GO:0050790 307 0.015
meiotic cell cycle GO:0051321 272 0.015
translational initiation GO:0006413 56 0.015
regulation of carbohydrate biosynthetic process GO:0043255 31 0.014
ribonucleoprotein complex subunit organization GO:0071826 152 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.014
response to topologically incorrect protein GO:0035966 38 0.014
nuclear transport GO:0051169 165 0.014
posttranslational protein targeting to membrane GO:0006620 17 0.014
ribonucleoprotein complex localization GO:0071166 46 0.014
cellular nitrogen compound catabolic process GO:0044270 494 0.014
sphingolipid metabolic process GO:0006665 41 0.014
gtp metabolic process GO:0046039 107 0.014
cofactor metabolic process GO:0051186 126 0.014
polysaccharide metabolic process GO:0005976 60 0.014
atp catabolic process GO:0006200 224 0.014
regulation of purine nucleotide metabolic process GO:1900542 109 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.014
mitotic cell cycle process GO:1903047 294 0.014
regulation of cellular amine metabolic process GO:0033238 21 0.013
cellular polysaccharide biosynthetic process GO:0033692 38 0.013
nucleoside triphosphate metabolic process GO:0009141 364 0.013
anion transport GO:0006820 145 0.013
response to organic cyclic compound GO:0014070 1 0.013
cellular response to organic substance GO:0071310 159 0.013
positive regulation of nucleoside metabolic process GO:0045979 97 0.013
regulation of metal ion transport GO:0010959 2 0.013
proteolysis GO:0006508 268 0.013
telomere maintenance GO:0000723 74 0.013
monovalent inorganic cation transport GO:0015672 78 0.013
sphingolipid biosynthetic process GO:0030148 29 0.013
regulation of protein metabolic process GO:0051246 237 0.013
endomembrane system organization GO:0010256 74 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 198 0.013
protein modification by small protein conjugation GO:0032446 144 0.013
conjugation GO:0000746 107 0.013
energy derivation by oxidation of organic compounds GO:0015980 125 0.013
regulation of mitosis GO:0007088 65 0.013
er to golgi vesicle mediated transport GO:0006888 86 0.013
mitotic recombination GO:0006312 55 0.012
mitotic spindle organization GO:0007052 30 0.012
organic anion transport GO:0015711 114 0.012
protein ubiquitination GO:0016567 118 0.012
response to pheromone GO:0019236 92 0.012
regulation of translation GO:0006417 89 0.012
nuclear export GO:0051168 124 0.012
nad metabolic process GO:0019674 25 0.012
glycerophospholipid biosynthetic process GO:0046474 68 0.012
regulation of purine nucleotide catabolic process GO:0033121 106 0.012
protein maturation GO:0051604 76 0.012
signal transduction involved in conjugation with cellular fusion GO:0032005 31 0.012
mitotic cell cycle phase transition GO:0044772 141 0.012
guanosine containing compound metabolic process GO:1901068 111 0.012
cellular transition metal ion homeostasis GO:0046916 59 0.012
positive regulation of nucleic acid templated transcription GO:1903508 286 0.012
asexual reproduction GO:0019954 48 0.012
ncrna processing GO:0034470 330 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
cellular chemical homeostasis GO:0055082 123 0.012
protein processing GO:0016485 64 0.012
lipid localization GO:0010876 60 0.012
ribosomal large subunit export from nucleus GO:0000055 27 0.012
fatty acid metabolic process GO:0006631 51 0.012
cellular response to topologically incorrect protein GO:0035967 32 0.012
ethanolamine containing compound metabolic process GO:0042439 21 0.012
cellular cation homeostasis GO:0030003 100 0.012
chromatin remodeling GO:0006338 80 0.012
protein sumoylation GO:0016925 17 0.011
positive regulation of rna metabolic process GO:0051254 294 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
cellular amino acid catabolic process GO:0009063 48 0.011
cellular ion homeostasis GO:0006873 112 0.011
peptidyl amino acid modification GO:0018193 116 0.011
regulation of biological quality GO:0065008 391 0.011
oxidation reduction process GO:0055114 353 0.011
positive regulation of rna biosynthetic process GO:1902680 286 0.011
cation transport GO:0006812 166 0.011
response to oxidative stress GO:0006979 99 0.011
positive regulation of hydrolase activity GO:0051345 112 0.011
regulation of cellular localization GO:0060341 50 0.011
regulation of carbohydrate catabolic process GO:0043470 12 0.011
cellular protein catabolic process GO:0044257 213 0.011
endoplasmic reticulum organization GO:0007029 30 0.011
protein complex disassembly GO:0043241 70 0.011
maintenance of location GO:0051235 66 0.011
heterocycle catabolic process GO:0046700 494 0.011
chromatin modification GO:0016568 200 0.011
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.011
ribonucleoside monophosphate catabolic process GO:0009158 224 0.011
response to uv GO:0009411 4 0.011
cell wall macromolecule biosynthetic process GO:0044038 24 0.010
aromatic compound catabolic process GO:0019439 491 0.010
ascospore formation GO:0030437 107 0.010
nuclear import GO:0051170 57 0.010
ribosome localization GO:0033750 46 0.010
nucleoside monophosphate catabolic process GO:0009125 224 0.010
nitrogen compound transport GO:0071705 212 0.010
golgi to plasma membrane transport GO:0006893 33 0.010
cellular response to oxidative stress GO:0034599 94 0.010
protein folding in endoplasmic reticulum GO:0034975 13 0.010

APA1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.011