|  | negative regulation of cellular metabolic process | GO:0031324 | 407 | 0.081 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.066 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of macromolecule metabolic process | GO:0010605 | 375 | 0.065 |  | 
                        
                        
                        
                        
                        
                            |  | macromolecule catabolic process | GO:0009057 | 383 | 0.061 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.061 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.061 |  | 
                        
                        
                        
                        
                        
                            |  | oxoacid metabolic process | GO:0043436 | 351 | 0.059 |  | 
                        
                        
                        
                        
                        
                            |  | sulfur compound metabolic process | GO:0006790 | 95 | 0.056 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of transcription dna templated | GO:0045892 | 258 | 0.054 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of cellular biosynthetic process | GO:0031327 | 312 | 0.053 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of protein metabolic process | GO:0051246 | 237 | 0.053 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of biosynthetic process | GO:0009890 | 312 | 0.052 |  | 
                        
                        
                        
                        
                        
                            |  | single organism catabolic process | GO:0044712 | 619 | 0.052 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.050 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of nitrogen compound metabolic process | GO:0051172 | 300 | 0.048 |  | 
                        
                        
                        
                        
                        
                            |  | cell communication | GO:0007154 | 345 | 0.046 |  | 
                        
                        
                        
                        
                        
                            |  | organic acid metabolic process | GO:0006082 | 352 | 0.045 |  | 
                        
                        
                        
                        
                        
                            |  | response to chemical | GO:0042221 | 390 | 0.045 |  | 
                        
                        
                        
                        
                        
                            |  | cellular amino acid metabolic process | GO:0006520 | 225 | 0.044 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.041 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of rna biosynthetic process | GO:1902679 | 260 | 0.040 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of gene expression | GO:0010628 | 321 | 0.040 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.040 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of gene expression | GO:0010629 | 312 | 0.040 |  | 
                        
                        
                        
                        
                        
                            |  | rrna metabolic process | GO:0016072 | 244 | 0.040 |  | 
                        
                        
                        
                        
                        
                            |  | carboxylic acid metabolic process | GO:0019752 | 338 | 0.039 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of biosynthetic process | GO:0009891 | 336 | 0.038 |  | 
                        
                        
                        
                        
                        
                            |  | small molecule biosynthetic process | GO:0044283 | 258 | 0.037 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cellular carbohydrate metabolic process | GO:0010675 | 41 | 0.036 |  | 
                        
                        
                        
                        
                        
                            |  | organonitrogen compound biosynthetic process | GO:1901566 | 314 | 0.036 |  | 
                        
                        
                        
                        
                        
                            |  | ascospore wall assembly | GO:0030476 | 52 | 0.035 |  | 
                        
                        
                        
                        
                        
                            |  | protein complex biogenesis | GO:0070271 | 314 | 0.034 |  | 
                        
                        
                        
                        
                        
                        
                        
                            |  | positive regulation of transcription dna templated | GO:0045893 | 286 | 0.034 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of rna metabolic process | GO:0051254 | 294 | 0.032 |  | 
                        
                        
                        
                        
                        
                            |  | establishment of protein localization to organelle | GO:0072594 | 278 | 0.032 |  | 
                        
                        
                        
                        
                        
                            |  | organophosphate metabolic process | GO:0019637 | 597 | 0.032 |  | 
                        
                        
                        
                        
                        
                            |  | ribosome biogenesis | GO:0042254 | 335 | 0.031 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of nucleic acid templated transcription | GO:1903507 | 260 | 0.031 |  | 
                        
                        
                        
                        
                        
                            |  | heterocycle catabolic process | GO:0046700 | 494 | 0.030 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cellular ketone metabolic process | GO:0010565 | 42 | 0.030 |  | 
                        
                        
                        
                        
                        
                            |  | dna repair | GO:0006281 | 236 | 0.029 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of biological quality | GO:0065008 | 391 | 0.029 |  | 
                        
                        
                        
                        
                        
                            |  | single organism signaling | GO:0044700 | 208 | 0.029 |  | 
                        
                        
                        
                        
                        
                            |  | chromatin silencing | GO:0006342 | 147 | 0.029 |  | 
                        
                        
                        
                        
                        
                            |  | cellular response to dna damage stimulus | GO:0006974 | 287 | 0.028 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of carbohydrate metabolic process | GO:0006109 | 43 | 0.028 |  | 
                        
                        
                        
                        
                        
                            |  | cellular response to chemical stimulus | GO:0070887 | 315 | 0.027 |  | 
                        
                        
                        
                        
                        
                            |  | reproductive process | GO:0022414 | 248 | 0.026 |  | 
                        
                        
                        
                        
                        
                            |  | cellular ketone metabolic process | GO:0042180 | 63 | 0.026 |  | 
                        
                        
                        
                        
                        
                            |  | establishment of organelle localization | GO:0051656 | 96 | 0.026 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cellular protein metabolic process | GO:0032268 | 232 | 0.025 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 252 | 0.025 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of catabolic process | GO:0009894 | 199 | 0.025 |  | 
                        
                        
                        
                        
                        
                            |  | rrna processing | GO:0006364 | 227 | 0.024 |  | 
                        
                        
                        
                        
                        
                            |  | establishment of protein localization | GO:0045184 | 367 | 0.023 |  | 
                        
                        
                        
                        
                        
                            |  | developmental process | GO:0032502 | 261 | 0.023 |  | 
                        
                        
                        
                        
                        
                            |  | single organism cellular localization | GO:1902580 | 375 | 0.023 |  | 
                        
                        
                        
                        
                        
                            |  | signaling | GO:0023052 | 208 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 289 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | macromolecule methylation | GO:0043414 | 85 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | cellular protein complex assembly | GO:0043623 | 209 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of macromolecule biosynthetic process | GO:0010558 | 291 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | carboxylic acid biosynthetic process | GO:0046394 | 152 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | methylation | GO:0032259 | 101 | 0.022 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of molecular function | GO:0065009 | 320 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | organelle localization | GO:0051640 | 128 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | cellular macromolecule catabolic process | GO:0044265 | 363 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of gene expression epigenetic | GO:0045814 | 147 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | mitotic cell cycle | GO:0000278 | 306 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | small molecule catabolic process | GO:0044282 | 88 | 0.021 |  | 
                        
                        
                        
                        
                        
                            |  | cellular lipid metabolic process | GO:0044255 | 229 | 0.020 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of rna metabolic process | GO:0051253 | 262 | 0.020 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of protein modification process | GO:0031399 | 110 | 0.020 |  | 
                        
                        
                        
                        
                        
                            |  | intracellular protein transport | GO:0006886 | 319 | 0.020 |  | 
                        
                        
                        
                        
                        
                            |  | aromatic compound catabolic process | GO:0019439 | 491 | 0.020 |  | 
                        
                        
                        
                        
                        
                            |  | membrane organization | GO:0061024 | 276 | 0.020 |  | 
                        
                        
                        
                        
                        
                            |  | fungal type cell wall organization | GO:0031505 | 145 | 0.019 |  | 
                        
                        
                        
                        
                        
                            |  | phosphorylation | GO:0016310 | 291 | 0.019 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 295 | 0.019 |  | 
                        
                        
                        
                        
                        
                            |  | intracellular signal transduction | GO:0035556 | 112 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | protein import | GO:0017038 | 122 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of gluconeogenesis | GO:0006111 | 16 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | cellular carbohydrate metabolic process | GO:0044262 | 135 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of signaling | GO:0023051 | 119 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of catalytic activity | GO:0050790 | 307 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | multi organism reproductive process | GO:0044703 | 216 | 0.018 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of phosphate metabolic process | GO:0019220 | 230 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | protein modification by small protein conjugation or removal | GO:0070647 | 172 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | intracellular protein transmembrane transport | GO:0065002 | 80 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | signal transduction | GO:0007165 | 208 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of protein metabolic process | GO:0051248 | 85 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | sexual sporulation resulting in formation of a cellular spore | GO:0043935 | 113 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | ncrna processing | GO:0034470 | 330 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | protein localization to organelle | GO:0033365 | 337 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | mitochondrial transport | GO:0006839 | 76 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | protein targeting | GO:0006605 | 272 | 0.017 |  | 
                        
                        
                        
                        
                        
                        
                        
                            |  | establishment of protein localization to membrane | GO:0090150 | 99 | 0.017 |  | 
                        
                        
                        
                        
                        
                            |  | protein complex assembly | GO:0006461 | 302 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cellular component organization | GO:0051128 | 334 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | ascospore wall biogenesis | GO:0070591 | 52 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | gene silencing | GO:0016458 | 151 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | organonitrogen compound catabolic process | GO:1901565 | 404 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of signal transduction | GO:0009966 | 114 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | cellular response to extracellular stimulus | GO:0031668 | 150 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | fungal type cell wall organization or biogenesis | GO:0071852 | 169 | 0.016 |  | 
                        
                        
                        
                        
                        
                            |  | carbohydrate derivative metabolic process | GO:1901135 | 549 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | cellular amino acid biosynthetic process | GO:0008652 | 118 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of phosphorus metabolic process | GO:0051174 | 230 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | establishment or maintenance of cell polarity | GO:0007163 | 96 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | oxidation reduction process | GO:0055114 | 353 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of protein metabolic process | GO:0051247 | 93 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | protein transmembrane transport | GO:0071806 | 82 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | glycerophospholipid metabolic process | GO:0006650 | 98 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | organic cyclic compound catabolic process | GO:1901361 | 499 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | protein folding | GO:0006457 | 94 | 0.015 |  | 
                        
                        
                        
                        
                        
                            |  | peptide metabolic process | GO:0006518 | 28 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | cellular nitrogen compound catabolic process | GO:0044270 | 494 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of cellular protein metabolic process | GO:0032270 | 89 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | cellular developmental process | GO:0048869 | 191 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | response to organic cyclic compound | GO:0014070 | 1 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | cellular modified amino acid metabolic process | GO:0006575 | 51 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | homeostatic process | GO:0042592 | 227 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | cellular amide metabolic process | GO:0043603 | 59 | 0.014 |  | 
                        
                        
                        
                        
                        
                            |  | organic acid biosynthetic process | GO:0016053 | 152 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | cell differentiation | GO:0030154 | 161 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | energy derivation by oxidation of organic compounds | GO:0015980 | 125 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | protein phosphorylation | GO:0006468 | 197 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | carboxylic acid transport | GO:0046942 | 74 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cellular catabolic process | GO:0031329 | 195 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | monocarboxylic acid metabolic process | GO:0032787 | 122 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | nucleocytoplasmic transport | GO:0006913 | 163 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of gene expression epigenetic | GO:0040029 | 147 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | secretion by cell | GO:0032940 | 50 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | cellular amine metabolic process | GO:0044106 | 51 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | cellular response to oxidative stress | GO:0034599 | 94 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of cellular component organization | GO:0051130 | 116 | 0.013 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of cell communication | GO:0010647 | 28 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of protein phosphorylation | GO:0001932 | 75 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | reproductive process in single celled organism | GO:0022413 | 145 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | protein transport | GO:0015031 | 345 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | dna recombination | GO:0006310 | 172 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | anatomical structure development | GO:0048856 | 160 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | alpha amino acid biosynthetic process | GO:1901607 | 91 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | amine metabolic process | GO:0009308 | 51 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | cell wall organization or biogenesis | GO:0071554 | 190 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | vesicle mediated transport | GO:0016192 | 335 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of cellular catabolic process | GO:0031331 | 128 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | phospholipid metabolic process | GO:0006644 | 125 | 0.012 |  | 
                        
                        
                        
                        
                        
                            |  | response to oxidative stress | GO:0006979 | 99 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of organelle organization | GO:0033043 | 243 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | mitotic cell cycle process | GO:1903047 | 294 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | cytoskeleton organization | GO:0007010 | 230 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 194 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | translation | GO:0006412 | 230 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of protein localization | GO:0032880 | 62 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of localization | GO:0032879 | 127 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | spore wall assembly | GO:0042244 | 52 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | nuclear export | GO:0051168 | 124 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | single organism developmental process | GO:0044767 | 258 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cellular amino acid metabolic process | GO:0006521 | 16 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | lipid modification | GO:0030258 | 37 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | protein modification by small protein conjugation | GO:0032446 | 144 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | negative regulation of phosphorus metabolic process | GO:0010563 | 49 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of cell communication | GO:0010646 | 124 | 0.011 |  | 
                        
                        
                        
                        
                        
                            |  | regulation of intracellular signal transduction | GO:1902531 | 78 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of intracellular transport | GO:0032388 | 4 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | water soluble vitamin metabolic process | GO:0006767 | 41 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | meiotic cell cycle | GO:0051321 | 272 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of organelle organization | GO:0010638 | 85 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | cell wall organization | GO:0071555 | 146 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | cellular response to external stimulus | GO:0071496 | 150 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | cell development | GO:0048468 | 107 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of cell death | GO:0010942 | 3 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of programmed cell death | GO:0043068 | 3 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | positive regulation of molecular function | GO:0044093 | 185 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | response to abiotic stimulus | GO:0009628 | 159 | 0.010 |  | 
                        
                        
                        
                        
                        
                            |  | dephosphorylation | GO:0016311 | 127 | 0.010 |  |